Amino acid dipepetide frequency for Yerba mate-associated circular DNA virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.367AlaAla: 4.367 ± 2.142
0.0AlaCys: 0.0 ± 0.0
2.62AlaAsp: 2.62 ± 1.307
6.987AlaGlu: 6.987 ± 2.83
4.367AlaPhe: 4.367 ± 2.36
4.367AlaGly: 4.367 ± 1.024
0.0AlaHis: 0.0 ± 0.0
0.0AlaIle: 0.0 ± 0.0
6.987AlaLys: 6.987 ± 2.892
5.24AlaLeu: 5.24 ± 3.623
0.0AlaMet: 0.0 ± 0.0
2.62AlaAsn: 2.62 ± 1.169
5.24AlaPro: 5.24 ± 1.683
3.493AlaGln: 3.493 ± 1.376
3.493AlaArg: 3.493 ± 1.691
1.747AlaSer: 1.747 ± 0.779
7.86AlaThr: 7.86 ± 2.046
3.493AlaVal: 3.493 ± 1.485
2.62AlaTrp: 2.62 ± 2.658
2.62AlaTyr: 2.62 ± 1.363
0.0AlaXaa: 0.0 ± 0.0
Cys
2.62CysAla: 2.62 ± 1.093
0.0CysCys: 0.0 ± 0.0
0.873CysAsp: 0.873 ± 1.229
0.873CysGlu: 0.873 ± 0.718
0.873CysPhe: 0.873 ± 1.229
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.873CysLeu: 0.873 ± 0.633
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
2.62CysSer: 2.62 ± 1.409
0.873CysThr: 0.873 ± 0.746
0.873CysVal: 0.873 ± 0.746
0.873CysTrp: 0.873 ± 0.746
0.873CysTyr: 0.873 ± 0.746
0.0CysXaa: 0.0 ± 0.0
Asp
2.62AspAla: 2.62 ± 0.604
0.0AspCys: 0.0 ± 0.0
2.62AspAsp: 2.62 ± 0.604
4.367AspGlu: 4.367 ± 1.024
0.873AspPhe: 0.873 ± 0.718
2.62AspGly: 2.62 ± 1.307
2.62AspHis: 2.62 ± 1.159
4.367AspIle: 4.367 ± 1.724
0.873AspLys: 0.873 ± 0.746
7.86AspLeu: 7.86 ± 2.744
0.0AspMet: 0.0 ± 0.59
0.0AspAsn: 0.0 ± 0.0
0.873AspPro: 0.873 ± 0.718
0.873AspGln: 0.873 ± 0.633
5.24AspArg: 5.24 ± 2.061
3.493AspSer: 3.493 ± 1.468
4.367AspThr: 4.367 ± 1.833
1.747AspVal: 1.747 ± 1.244
3.493AspTrp: 3.493 ± 1.558
1.747AspTyr: 1.747 ± 0.734
0.0AspXaa: 0.0 ± 0.0
Glu
1.747GluAla: 1.747 ± 1.183
0.0GluCys: 0.0 ± 0.0
0.873GluAsp: 0.873 ± 1.068
4.367GluGlu: 4.367 ± 2.645
3.493GluPhe: 3.493 ± 2.014
1.747GluGly: 1.747 ± 1.363
0.873GluHis: 0.873 ± 1.068
2.62GluIle: 2.62 ± 1.536
0.873GluLys: 0.873 ± 0.633
6.114GluLeu: 6.114 ± 2.015
1.747GluMet: 1.747 ± 1.183
0.873GluAsn: 0.873 ± 0.718
3.493GluPro: 3.493 ± 1.994
2.62GluGln: 2.62 ± 1.307
4.367GluArg: 4.367 ± 1.655
2.62GluSer: 2.62 ± 1.574
4.367GluThr: 4.367 ± 1.4
0.873GluVal: 0.873 ± 0.633
0.873GluTrp: 0.873 ± 1.229
0.873GluTyr: 0.873 ± 0.633
0.0GluXaa: 0.0 ± 0.0
Phe
3.493PheAla: 3.493 ± 2.488
0.873PheCys: 0.873 ± 1.229
4.367PheAsp: 4.367 ± 1.119
0.0PheGlu: 0.0 ± 0.0
0.0PhePhe: 0.0 ± 0.0
3.493PheGly: 3.493 ± 1.558
0.873PheHis: 0.873 ± 0.633
3.493PheIle: 3.493 ± 1.074
0.873PheLys: 0.873 ± 0.746
3.493PheLeu: 3.493 ± 2.367
0.0PheMet: 0.0 ± 0.0
2.62PheAsn: 2.62 ± 1.363
1.747PhePro: 1.747 ± 1.244
1.747PheGln: 1.747 ± 1.267
0.873PheArg: 0.873 ± 0.718
3.493PheSer: 3.493 ± 0.901
2.62PheThr: 2.62 ± 1.307
4.367PheVal: 4.367 ± 1.706
0.0PheTrp: 0.0 ± 0.0
0.873PheTyr: 0.873 ± 0.718
0.0PheXaa: 0.0 ± 0.0
Gly
6.114GlyAla: 6.114 ± 1.372
0.0GlyCys: 0.0 ± 0.0
3.493GlyAsp: 3.493 ± 1.434
1.747GlyGlu: 1.747 ± 1.111
0.0GlyPhe: 0.0 ± 0.0
6.987GlyGly: 6.987 ± 1.651
0.873GlyHis: 0.873 ± 0.633
1.747GlyIle: 1.747 ± 1.492
4.367GlyLys: 4.367 ± 1.724
5.24GlyLeu: 5.24 ± 1.811
0.873GlyMet: 0.873 ± 0.746
1.747GlyAsn: 1.747 ± 1.492
0.873GlyPro: 0.873 ± 0.718
2.62GlyGln: 2.62 ± 2.058
5.24GlyArg: 5.24 ± 2.776
6.114GlySer: 6.114 ± 2.157
4.367GlyThr: 4.367 ± 1.024
2.62GlyVal: 2.62 ± 1.637
0.0GlyTrp: 0.0 ± 0.0
1.747GlyTyr: 1.747 ± 0.832
0.0GlyXaa: 0.0 ± 0.0
His
0.873HisAla: 0.873 ± 1.068
1.747HisCys: 1.747 ± 1.435
0.873HisAsp: 0.873 ± 0.718
0.873HisGlu: 0.873 ± 0.746
0.0HisPhe: 0.0 ± 0.0
2.62HisGly: 2.62 ± 1.169
2.62HisHis: 2.62 ± 1.569
3.493HisIle: 3.493 ± 1.976
0.0HisLys: 0.0 ± 0.0
4.367HisLeu: 4.367 ± 1.007
0.0HisMet: 0.0 ± 0.0
1.747HisAsn: 1.747 ± 0.832
3.493HisPro: 3.493 ± 1.731
0.0HisGln: 0.0 ± 0.0
0.873HisArg: 0.873 ± 1.068
4.367HisSer: 4.367 ± 1.889
1.747HisThr: 1.747 ± 0.734
1.747HisVal: 1.747 ± 0.734
0.873HisTrp: 0.873 ± 0.746
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.747IleAla: 1.747 ± 1.267
0.0IleCys: 0.0 ± 0.0
3.493IleAsp: 3.493 ± 1.074
0.873IleGlu: 0.873 ± 0.718
4.367IlePhe: 4.367 ± 0.954
0.873IleGly: 0.873 ± 0.718
4.367IleHis: 4.367 ± 1.724
5.24IleIle: 5.24 ± 1.385
3.493IleLys: 3.493 ± 2.014
2.62IleLeu: 2.62 ± 1.057
2.62IleMet: 2.62 ± 1.208
2.62IleAsn: 2.62 ± 1.072
1.747IlePro: 1.747 ± 1.435
5.24IleGln: 5.24 ± 2.337
4.367IleArg: 4.367 ± 1.478
2.62IleSer: 2.62 ± 1.536
0.873IleThr: 0.873 ± 0.633
0.0IleVal: 0.0 ± 0.0
3.493IleTrp: 3.493 ± 2.014
0.873IleTyr: 0.873 ± 0.633
0.0IleXaa: 0.0 ± 0.0
Lys
0.873LysAla: 0.873 ± 0.746
0.0LysCys: 0.0 ± 0.0
3.493LysAsp: 3.493 ± 1.074
2.62LysGlu: 2.62 ± 1.057
1.747LysPhe: 1.747 ± 0.779
0.0LysGly: 0.0 ± 0.0
0.0LysHis: 0.0 ± 0.0
1.747LysIle: 1.747 ± 0.734
0.873LysLys: 0.873 ± 0.746
4.367LysLeu: 4.367 ± 1.119
1.747LysMet: 1.747 ± 0.991
0.873LysAsn: 0.873 ± 0.718
0.0LysPro: 0.0 ± 0.0
2.62LysGln: 2.62 ± 1.388
2.62LysArg: 2.62 ± 1.409
5.24LysSer: 5.24 ± 1.209
0.873LysThr: 0.873 ± 0.718
0.0LysVal: 0.0 ± 0.0
0.0LysTrp: 0.0 ± 0.0
5.24LysTyr: 5.24 ± 3.458
0.0LysXaa: 0.0 ± 0.0
Leu
6.987LeuAla: 6.987 ± 2.909
0.873LeuCys: 0.873 ± 0.746
4.367LeuAsp: 4.367 ± 1.473
4.367LeuGlu: 4.367 ± 1.423
0.873LeuPhe: 0.873 ± 0.633
1.747LeuGly: 1.747 ± 1.198
3.493LeuHis: 3.493 ± 1.468
5.24LeuIle: 5.24 ± 1.535
0.873LeuLys: 0.873 ± 0.746
6.987LeuLeu: 6.987 ± 3.234
2.62LeuMet: 2.62 ± 1.169
3.493LeuAsn: 3.493 ± 1.558
6.114LeuPro: 6.114 ± 2.945
1.747LeuGln: 1.747 ± 0.779
5.24LeuArg: 5.24 ± 2.09
11.354LeuSer: 11.354 ± 2.818
7.86LeuThr: 7.86 ± 1.663
8.734LeuVal: 8.734 ± 2.512
0.873LeuTrp: 0.873 ± 0.633
2.62LeuTyr: 2.62 ± 1.231
0.0LeuXaa: 0.0 ± 0.0
Met
0.873MetAla: 0.873 ± 0.746
0.873MetCys: 0.873 ± 0.746
0.0MetAsp: 0.0 ± 0.0
1.747MetGlu: 1.747 ± 2.457
0.0MetPhe: 0.0 ± 0.0
1.747MetGly: 1.747 ± 0.832
0.873MetHis: 0.873 ± 0.633
0.873MetIle: 0.873 ± 0.633
0.0MetLys: 0.0 ± 0.0
0.873MetLeu: 0.873 ± 0.746
0.0MetMet: 0.0 ± 0.0
1.747MetAsn: 1.747 ± 0.779
1.747MetPro: 1.747 ± 0.832
2.62MetGln: 2.62 ± 1.569
0.873MetArg: 0.873 ± 0.746
1.747MetSer: 1.747 ± 1.183
1.747MetThr: 1.747 ± 1.267
0.873MetVal: 0.873 ± 0.746
0.873MetTrp: 0.873 ± 0.633
0.873MetTyr: 0.873 ± 0.746
0.0MetXaa: 0.0 ± 0.0
Asn
2.62AsnAla: 2.62 ± 1.363
0.873AsnCys: 0.873 ± 0.633
1.747AsnAsp: 1.747 ± 0.832
1.747AsnGlu: 1.747 ± 1.111
0.0AsnPhe: 0.0 ± 0.0
3.493AsnGly: 3.493 ± 0.825
0.873AsnHis: 0.873 ± 0.633
0.873AsnIle: 0.873 ± 0.633
1.747AsnLys: 1.747 ± 0.779
1.747AsnLeu: 1.747 ± 0.779
1.747AsnMet: 1.747 ± 1.37
3.493AsnAsn: 3.493 ± 1.074
2.62AsnPro: 2.62 ± 1.307
0.873AsnGln: 0.873 ± 0.746
1.747AsnArg: 1.747 ± 1.238
3.493AsnSer: 3.493 ± 2.08
3.493AsnThr: 3.493 ± 1.143
2.62AsnVal: 2.62 ± 1.388
0.873AsnTrp: 0.873 ± 0.718
1.747AsnTyr: 1.747 ± 0.734
0.0AsnXaa: 0.0 ± 0.0
Pro
1.747ProAla: 1.747 ± 1.238
0.0ProCys: 0.0 ± 0.0
2.62ProAsp: 2.62 ± 1.363
1.747ProGlu: 1.747 ± 0.734
2.62ProPhe: 2.62 ± 1.307
0.873ProGly: 0.873 ± 0.746
3.493ProHis: 3.493 ± 1.365
3.493ProIle: 3.493 ± 1.365
0.873ProLys: 0.873 ± 0.718
5.24ProLeu: 5.24 ± 1.002
0.873ProMet: 0.873 ± 0.633
0.873ProAsn: 0.873 ± 0.633
4.367ProPro: 4.367 ± 1.9
3.493ProGln: 3.493 ± 1.282
1.747ProArg: 1.747 ± 1.435
7.86ProSer: 7.86 ± 2.312
3.493ProThr: 3.493 ± 0.917
2.62ProVal: 2.62 ± 1.388
2.62ProTrp: 2.62 ± 1.363
1.747ProTyr: 1.747 ± 0.734
0.0ProXaa: 0.0 ± 0.0
Gln
3.493GlnAla: 3.493 ± 1.365
0.873GlnCys: 0.873 ± 0.746
0.873GlnAsp: 0.873 ± 0.633
0.873GlnGlu: 0.873 ± 0.633
1.747GlnPhe: 1.747 ± 1.267
2.62GlnGly: 2.62 ± 1.072
1.747GlnHis: 1.747 ± 1.435
2.62GlnIle: 2.62 ± 0.604
0.0GlnLys: 0.0 ± 0.0
9.607GlnLeu: 9.607 ± 2.624
0.0GlnMet: 0.0 ± 0.0
1.747GlnAsn: 1.747 ± 1.183
1.747GlnPro: 1.747 ± 0.832
3.493GlnGln: 3.493 ± 1.468
6.114GlnArg: 6.114 ± 1.715
2.62GlnSer: 2.62 ± 1.9
5.24GlnThr: 5.24 ± 1.467
1.747GlnVal: 1.747 ± 1.198
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
7.86ArgAla: 7.86 ± 3.088
0.0ArgCys: 0.0 ± 0.0
4.367ArgAsp: 4.367 ± 1.31
3.493ArgGlu: 3.493 ± 1.691
2.62ArgPhe: 2.62 ± 1.822
5.24ArgGly: 5.24 ± 0.981
2.62ArgHis: 2.62 ± 1.363
0.873ArgIle: 0.873 ± 0.718
3.493ArgLys: 3.493 ± 1.485
6.987ArgLeu: 6.987 ± 2.684
1.747ArgMet: 1.747 ± 1.492
0.873ArgAsn: 0.873 ± 0.718
1.747ArgPro: 1.747 ± 0.832
1.747ArgGln: 1.747 ± 0.734
10.48ArgArg: 10.48 ± 4.533
6.114ArgSer: 6.114 ± 1.767
5.24ArgThr: 5.24 ± 0.981
3.493ArgVal: 3.493 ± 1.625
1.747ArgTrp: 1.747 ± 0.832
1.747ArgTyr: 1.747 ± 1.244
0.0ArgXaa: 0.0 ± 0.0
Ser
6.987SerAla: 6.987 ± 1.197
0.873SerCys: 0.873 ± 0.746
2.62SerAsp: 2.62 ± 1.569
2.62SerGlu: 2.62 ± 1.569
6.114SerPhe: 6.114 ± 1.685
6.114SerGly: 6.114 ± 2.904
2.62SerHis: 2.62 ± 1.057
6.114SerIle: 6.114 ± 1.372
3.493SerLys: 3.493 ± 1.365
3.493SerLeu: 3.493 ± 2.339
2.62SerMet: 2.62 ± 1.119
7.86SerAsn: 7.86 ± 2.794
6.987SerPro: 6.987 ± 2.572
6.114SerGln: 6.114 ± 2.322
7.86SerArg: 7.86 ± 2.393
15.721SerSer: 15.721 ± 3.415
7.86SerThr: 7.86 ± 2.134
1.747SerVal: 1.747 ± 0.779
0.873SerTrp: 0.873 ± 0.633
3.493SerTyr: 3.493 ± 2.08
0.0SerXaa: 0.0 ± 0.0
Thr
6.987ThrAla: 6.987 ± 1.834
0.873ThrCys: 0.873 ± 0.746
6.114ThrAsp: 6.114 ± 0.976
1.747ThrGlu: 1.747 ± 1.238
3.493ThrPhe: 3.493 ± 0.917
4.367ThrGly: 4.367 ± 1.833
2.62ThrHis: 2.62 ± 1.208
5.24ThrIle: 5.24 ± 1.385
1.747ThrLys: 1.747 ± 1.435
2.62ThrLeu: 2.62 ± 1.057
1.747ThrMet: 1.747 ± 0.779
1.747ThrAsn: 1.747 ± 0.734
4.367ThrPro: 4.367 ± 1.119
0.873ThrGln: 0.873 ± 0.633
5.24ThrArg: 5.24 ± 2.522
10.48ThrSer: 10.48 ± 2.817
4.367ThrThr: 4.367 ± 1.024
7.86ThrVal: 7.86 ± 3.123
1.747ThrTrp: 1.747 ± 0.779
2.62ThrTyr: 2.62 ± 2.485
0.0ThrXaa: 0.0 ± 0.0
Val
3.493ValAla: 3.493 ± 1.476
1.747ValCys: 1.747 ± 0.779
1.747ValAsp: 1.747 ± 1.492
3.493ValGlu: 3.493 ± 0.901
3.493ValPhe: 3.493 ± 1.376
2.62ValGly: 2.62 ± 1.687
0.873ValHis: 0.873 ± 0.633
1.747ValIle: 1.747 ± 0.734
0.0ValLys: 0.0 ± 0.0
4.367ValLeu: 4.367 ± 1.242
1.747ValMet: 1.747 ± 1.217
2.62ValAsn: 2.62 ± 1.409
2.62ValPro: 2.62 ± 1.822
2.62ValGln: 2.62 ± 0.604
3.493ValArg: 3.493 ± 1.778
4.367ValSer: 4.367 ± 2.19
3.493ValThr: 3.493 ± 0.901
5.24ValVal: 5.24 ± 2.497
0.873ValTrp: 0.873 ± 0.633
2.62ValTyr: 2.62 ± 1.822
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.873TrpCys: 0.873 ± 1.229
0.873TrpAsp: 0.873 ± 0.718
0.0TrpGlu: 0.0 ± 0.0
1.747TrpPhe: 1.747 ± 0.734
2.62TrpGly: 2.62 ± 1.169
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.747TrpLys: 1.747 ± 1.492
2.62TrpLeu: 2.62 ± 1.237
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
1.747TrpPro: 1.747 ± 0.832
2.62TrpGln: 2.62 ± 2.153
2.62TrpArg: 2.62 ± 1.388
1.747TrpSer: 1.747 ± 1.183
2.62TrpThr: 2.62 ± 1.388
0.873TrpVal: 0.873 ± 1.229
1.747TrpTrp: 1.747 ± 1.238
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.62TyrAla: 2.62 ± 2.384
1.747TyrCys: 1.747 ± 1.244
3.493TyrAsp: 3.493 ± 1.485
0.873TyrGlu: 0.873 ± 1.229
0.873TyrPhe: 0.873 ± 0.746
2.62TyrGly: 2.62 ± 1.388
0.873TyrHis: 0.873 ± 0.746
1.747TyrIle: 1.747 ± 1.435
2.62TyrLys: 2.62 ± 1.822
1.747TyrLeu: 1.747 ± 0.779
0.0TyrMet: 0.0 ± 0.0
0.873TyrAsn: 0.873 ± 0.633
0.873TyrPro: 0.873 ± 0.718
1.747TyrGln: 1.747 ± 1.363
0.0TyrArg: 0.0 ± 0.0
4.367TyrSer: 4.367 ± 1.9
3.493TyrThr: 3.493 ± 2.08
1.747TyrVal: 1.747 ± 1.435
0.0TyrTrp: 0.0 ± 0.0
1.747TyrTyr: 1.747 ± 1.244
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1146 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski