Amino acid dipepetide frequency for Changjiang crawfish virus 5

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.33AlaAla: 2.33 ± 2.011
0.999AlaCys: 0.999 ± 0.131
3.329AlaAsp: 3.329 ± 1.503
2.996AlaGlu: 2.996 ± 1.033
0.999AlaPhe: 0.999 ± 0.77
2.663AlaGly: 2.663 ± 0.715
1.332AlaHis: 1.332 ± 0.601
3.995AlaIle: 3.995 ± 2.443
3.329AlaLys: 3.329 ± 0.864
5.659AlaLeu: 5.659 ± 0.96
0.999AlaMet: 0.999 ± 0.77
2.996AlaAsn: 2.996 ± 1.033
3.329AlaPro: 3.329 ± 0.225
0.999AlaGln: 0.999 ± 0.508
3.995AlaArg: 3.995 ± 0.114
4.993AlaSer: 4.993 ± 1.935
4.993AlaThr: 4.993 ± 1.935
3.329AlaVal: 3.329 ± 0.225
0.666AlaTrp: 0.666 ± 0.338
3.329AlaTyr: 3.329 ± 0.414
0.0AlaXaa: 0.0 ± 0.0
Cys
0.999CysAla: 0.999 ± 0.131
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.332CysGlu: 1.332 ± 0.038
0.666CysPhe: 0.666 ± 0.338
1.997CysGly: 1.997 ± 0.263
0.0CysHis: 0.0 ± 0.0
1.332CysIle: 1.332 ± 0.677
0.999CysLys: 0.999 ± 0.508
1.997CysLeu: 1.997 ± 0.376
0.333CysMet: 0.333 ± 0.169
0.666CysAsn: 0.666 ± 0.94
0.333CysPro: 0.333 ± 0.169
0.333CysGln: 0.333 ± 0.169
0.666CysArg: 0.666 ± 0.338
0.999CysSer: 0.999 ± 0.131
1.332CysThr: 1.332 ± 0.038
1.332CysVal: 1.332 ± 0.677
0.333CysTrp: 0.333 ± 0.169
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.995AspAla: 3.995 ± 2.443
1.997AspCys: 1.997 ± 1.015
5.659AspAsp: 5.659 ± 0.96
3.329AspGlu: 3.329 ± 1.692
2.996AspPhe: 2.996 ± 0.884
1.664AspGly: 1.664 ± 0.432
1.332AspHis: 1.332 ± 0.038
4.328AspIle: 4.328 ± 0.922
2.996AspLys: 2.996 ± 1.523
7.989AspLeu: 7.989 ± 0.227
2.996AspMet: 2.996 ± 0.884
1.664AspAsn: 1.664 ± 0.846
1.332AspPro: 1.332 ± 0.601
0.999AspGln: 0.999 ± 0.131
1.997AspArg: 1.997 ± 1.015
3.329AspSer: 3.329 ± 1.053
3.329AspThr: 3.329 ± 2.781
2.996AspVal: 2.996 ± 0.245
0.999AspTrp: 0.999 ± 0.131
0.999AspTyr: 0.999 ± 0.508
0.0AspXaa: 0.0 ± 0.0
Glu
1.664GluAla: 1.664 ± 0.207
0.666GluCys: 0.666 ± 0.301
2.996GluAsp: 2.996 ± 1.523
3.662GluGlu: 3.662 ± 1.862
2.33GluPhe: 2.33 ± 0.733
3.329GluGly: 3.329 ± 0.414
2.33GluHis: 2.33 ± 0.094
2.663GluIle: 2.663 ± 0.076
3.662GluLys: 3.662 ± 1.223
3.662GluLeu: 3.662 ± 1.862
2.33GluMet: 2.33 ± 0.094
2.996GluAsn: 2.996 ± 0.394
2.663GluPro: 2.663 ± 0.715
1.664GluGln: 1.664 ± 0.207
3.662GluArg: 3.662 ± 0.583
3.662GluSer: 3.662 ± 1.862
4.993GluThr: 4.993 ± 1.296
3.329GluVal: 3.329 ± 1.692
0.999GluTrp: 0.999 ± 0.508
2.663GluTyr: 2.663 ± 0.076
0.0GluXaa: 0.0 ± 0.0
Phe
3.662PheAla: 3.662 ± 1.334
0.333PheCys: 0.333 ± 0.47
1.997PheAsp: 1.997 ± 1.015
2.996PheGlu: 2.996 ± 0.884
1.997PhePhe: 1.997 ± 1.015
1.332PheGly: 1.332 ± 0.677
1.664PheHis: 1.664 ± 0.432
1.997PheIle: 1.997 ± 0.902
3.662PheLys: 3.662 ± 0.583
3.329PheLeu: 3.329 ± 0.864
2.663PheMet: 2.663 ± 0.076
2.33PheAsn: 2.33 ± 0.546
0.666PhePro: 0.666 ± 0.338
4.328PheGln: 4.328 ± 0.922
1.997PheArg: 1.997 ± 1.015
3.329PheSer: 3.329 ± 2.142
3.329PheThr: 3.329 ± 0.414
4.993PheVal: 4.993 ± 1.26
1.332PheTrp: 1.332 ± 0.677
2.33PheTyr: 2.33 ± 1.372
0.0PheXaa: 0.0 ± 0.0
Gly
2.996GlyAla: 2.996 ± 1.672
1.332GlyCys: 1.332 ± 0.677
3.329GlyAsp: 3.329 ± 1.053
1.664GlyGlu: 1.664 ± 0.207
2.33GlyPhe: 2.33 ± 0.094
3.329GlyGly: 3.329 ± 0.225
0.999GlyHis: 0.999 ± 0.77
3.329GlyIle: 3.329 ± 0.414
2.33GlyLys: 2.33 ± 1.185
3.995GlyLeu: 3.995 ± 1.165
0.999GlyMet: 0.999 ± 0.508
2.33GlyAsn: 2.33 ± 0.546
1.997GlyPro: 1.997 ± 0.263
0.333GlyGln: 0.333 ± 0.169
3.329GlyArg: 3.329 ± 0.225
3.995GlySer: 3.995 ± 0.114
3.995GlyThr: 3.995 ± 1.804
2.996GlyVal: 2.996 ± 0.884
0.666GlyTrp: 0.666 ± 0.301
1.997GlyTyr: 1.997 ± 0.263
0.0GlyXaa: 0.0 ± 0.0
His
1.664HisAla: 1.664 ± 0.846
0.333HisCys: 0.333 ± 0.169
1.332HisAsp: 1.332 ± 0.038
1.664HisGlu: 1.664 ± 0.207
0.999HisPhe: 0.999 ± 0.131
1.664HisGly: 1.664 ± 0.846
1.332HisHis: 1.332 ± 0.038
1.664HisIle: 1.664 ± 0.432
1.664HisLys: 1.664 ± 0.846
1.997HisLeu: 1.997 ± 0.902
0.999HisMet: 0.999 ± 0.131
2.33HisAsn: 2.33 ± 0.094
0.0HisPro: 0.0 ± 0.0
0.666HisGln: 0.666 ± 0.301
0.666HisArg: 0.666 ± 0.301
3.995HisSer: 3.995 ± 0.525
1.664HisThr: 1.664 ± 0.207
1.332HisVal: 1.332 ± 0.601
0.666HisTrp: 0.666 ± 0.301
0.666HisTyr: 0.666 ± 0.338
0.0HisXaa: 0.0 ± 0.0
Ile
4.328IleAla: 4.328 ± 0.922
0.999IleCys: 0.999 ± 0.508
2.663IleAsp: 2.663 ± 0.076
2.996IleGlu: 2.996 ± 0.245
2.663IlePhe: 2.663 ± 0.563
1.997IleGly: 1.997 ± 0.902
3.329IleHis: 3.329 ± 1.053
2.663IleIle: 2.663 ± 0.715
4.328IleLys: 4.328 ± 0.283
4.328IleLeu: 4.328 ± 1.561
1.332IleMet: 1.332 ± 0.677
4.66IleAsn: 4.66 ± 0.826
3.329IlePro: 3.329 ± 0.864
1.664IleGln: 1.664 ± 0.207
3.329IleArg: 3.329 ± 0.225
5.326IleSer: 5.326 ± 1.766
6.658IleThr: 6.658 ± 1.089
4.328IleVal: 4.328 ± 0.283
0.999IleTrp: 0.999 ± 0.131
2.663IleTyr: 2.663 ± 0.563
0.0IleXaa: 0.0 ± 0.0
Lys
3.329LysAla: 3.329 ± 0.414
1.332LysCys: 1.332 ± 0.038
2.663LysAsp: 2.663 ± 1.354
5.326LysGlu: 5.326 ± 1.43
4.328LysPhe: 4.328 ± 0.283
2.663LysGly: 2.663 ± 1.354
1.664LysHis: 1.664 ± 0.846
4.993LysIle: 4.993 ± 0.621
2.996LysLys: 2.996 ± 0.884
5.326LysLeu: 5.326 ± 2.069
2.663LysMet: 2.663 ± 0.076
2.33LysAsn: 2.33 ± 1.185
3.662LysPro: 3.662 ± 0.583
2.663LysGln: 2.663 ± 0.715
2.33LysArg: 2.33 ± 0.546
5.992LysSer: 5.992 ± 1.768
0.999LysThr: 0.999 ± 0.508
2.663LysVal: 2.663 ± 0.715
0.999LysTrp: 0.999 ± 0.508
3.995LysTyr: 3.995 ± 0.753
0.0LysXaa: 0.0 ± 0.0
Leu
2.663LeuAla: 2.663 ± 0.563
1.997LeuCys: 1.997 ± 0.376
7.324LeuAsp: 7.324 ± 0.528
3.329LeuGlu: 3.329 ± 0.225
4.993LeuPhe: 4.993 ± 1.26
2.663LeuGly: 2.663 ± 0.076
1.664LeuHis: 1.664 ± 0.846
6.658LeuIle: 6.658 ± 0.828
6.658LeuLys: 6.658 ± 2.107
8.988LeuLeu: 8.988 ± 0.096
2.33LeuMet: 2.33 ± 0.546
5.992LeuAsn: 5.992 ± 0.49
5.992LeuPro: 5.992 ± 1.427
2.33LeuGln: 2.33 ± 0.546
3.329LeuArg: 3.329 ± 0.864
6.991LeuSer: 6.991 ± 3.476
5.659LeuThr: 5.659 ± 0.96
6.991LeuVal: 6.991 ± 0.998
1.332LeuTrp: 1.332 ± 0.601
2.33LeuTyr: 2.33 ± 1.185
0.0LeuXaa: 0.0 ± 0.0
Met
1.332MetAla: 1.332 ± 0.038
0.0MetCys: 0.0 ± 0.0
2.33MetAsp: 2.33 ± 0.094
3.662MetGlu: 3.662 ± 0.583
1.332MetPhe: 1.332 ± 0.677
1.332MetGly: 1.332 ± 0.601
1.332MetHis: 1.332 ± 0.038
1.664MetIle: 1.664 ± 0.846
2.33MetLys: 2.33 ± 0.546
3.329MetLeu: 3.329 ± 0.225
0.666MetMet: 0.666 ± 0.94
1.997MetAsn: 1.997 ± 0.263
1.332MetPro: 1.332 ± 0.677
0.333MetGln: 0.333 ± 0.47
2.33MetArg: 2.33 ± 0.546
2.33MetSer: 2.33 ± 0.546
0.999MetThr: 0.999 ± 0.77
1.664MetVal: 1.664 ± 0.846
0.333MetTrp: 0.333 ± 0.47
0.999MetTyr: 0.999 ± 0.77
0.0MetXaa: 0.0 ± 0.0
Asn
3.662AsnAla: 3.662 ± 1.973
0.999AsnCys: 0.999 ± 0.508
3.329AsnAsp: 3.329 ± 1.053
1.997AsnGlu: 1.997 ± 0.902
3.329AsnPhe: 3.329 ± 0.414
2.663AsnGly: 2.663 ± 0.563
2.663AsnHis: 2.663 ± 0.563
2.996AsnIle: 2.996 ± 0.394
3.329AsnLys: 3.329 ± 1.053
3.995AsnLeu: 3.995 ± 1.392
1.664AsnMet: 1.664 ± 0.232
2.33AsnAsn: 2.33 ± 0.094
1.997AsnPro: 1.997 ± 0.376
1.664AsnGln: 1.664 ± 0.432
1.997AsnArg: 1.997 ± 1.015
2.663AsnSer: 2.663 ± 0.563
1.997AsnThr: 1.997 ± 0.902
4.66AsnVal: 4.66 ± 0.187
0.666AsnTrp: 0.666 ± 0.301
3.662AsnTyr: 3.662 ± 0.695
0.0AsnXaa: 0.0 ± 0.0
Pro
1.664ProAla: 1.664 ± 0.846
0.333ProCys: 0.333 ± 0.47
1.997ProAsp: 1.997 ± 1.541
2.33ProGlu: 2.33 ± 1.185
3.995ProPhe: 3.995 ± 0.525
2.33ProGly: 2.33 ± 0.546
0.666ProHis: 0.666 ± 0.338
3.329ProIle: 3.329 ± 1.503
2.33ProLys: 2.33 ± 0.733
4.66ProLeu: 4.66 ± 0.452
1.664ProMet: 1.664 ± 0.846
2.663ProAsn: 2.663 ± 0.076
1.332ProPro: 1.332 ± 0.601
0.666ProGln: 0.666 ± 0.338
1.997ProArg: 1.997 ± 0.902
3.662ProSer: 3.662 ± 0.056
1.997ProThr: 1.997 ± 2.18
5.992ProVal: 5.992 ± 2.066
0.666ProTrp: 0.666 ± 0.301
3.662ProTyr: 3.662 ± 1.334
0.0ProXaa: 0.0 ± 0.0
Gln
1.664GlnAla: 1.664 ± 0.432
0.0GlnCys: 0.0 ± 0.0
0.333GlnAsp: 0.333 ± 0.169
1.332GlnGlu: 1.332 ± 0.677
0.999GlnPhe: 0.999 ± 0.131
2.33GlnGly: 2.33 ± 0.546
0.333GlnHis: 0.333 ± 0.47
1.332GlnIle: 1.332 ± 0.038
1.664GlnLys: 1.664 ± 0.846
3.662GlnLeu: 3.662 ± 1.334
1.332GlnMet: 1.332 ± 0.172
1.664GlnAsn: 1.664 ± 0.207
2.996GlnPro: 2.996 ± 0.245
0.999GlnGln: 0.999 ± 0.508
0.666GlnArg: 0.666 ± 0.338
1.997GlnSer: 1.997 ± 0.376
2.33GlnThr: 2.33 ± 0.546
1.332GlnVal: 1.332 ± 0.677
0.333GlnTrp: 0.333 ± 0.169
0.999GlnTyr: 0.999 ± 0.508
0.0GlnXaa: 0.0 ± 0.0
Arg
2.663ArgAla: 2.663 ± 0.563
0.0ArgCys: 0.0 ± 0.0
3.662ArgAsp: 3.662 ± 1.223
1.332ArgGlu: 1.332 ± 0.677
2.996ArgPhe: 2.996 ± 0.394
1.997ArgGly: 1.997 ± 0.263
0.666ArgHis: 0.666 ± 0.338
4.993ArgIle: 4.993 ± 0.621
4.66ArgLys: 4.66 ± 1.73
3.995ArgLeu: 3.995 ± 0.753
1.997ArgMet: 1.997 ± 0.263
1.997ArgAsn: 1.997 ± 1.015
1.664ArgPro: 1.664 ± 1.071
0.999ArgGln: 0.999 ± 0.131
3.329ArgArg: 3.329 ± 1.692
2.996ArgSer: 2.996 ± 0.394
1.664ArgThr: 1.664 ± 0.846
3.329ArgVal: 3.329 ± 0.864
0.333ArgTrp: 0.333 ± 0.169
1.332ArgTyr: 1.332 ± 0.601
0.0ArgXaa: 0.0 ± 0.0
Ser
6.325SerAla: 6.325 ± 1.897
0.999SerCys: 0.999 ± 0.131
4.328SerAsp: 4.328 ± 0.995
4.66SerGlu: 4.66 ± 1.73
3.329SerPhe: 3.329 ± 0.225
4.993SerGly: 4.993 ± 0.657
1.997SerHis: 1.997 ± 0.263
3.662SerIle: 3.662 ± 0.695
4.66SerLys: 4.66 ± 1.091
7.324SerLeu: 7.324 ± 1.389
2.33SerMet: 2.33 ± 0.546
2.996SerAsn: 2.996 ± 0.245
4.328SerPro: 4.328 ± 1.634
2.996SerGln: 2.996 ± 0.884
2.996SerArg: 2.996 ± 1.033
4.66SerSer: 4.66 ± 0.826
4.328SerThr: 4.328 ± 2.273
5.326SerVal: 5.326 ± 2.405
1.332SerTrp: 1.332 ± 0.038
2.33SerTyr: 2.33 ± 0.094
0.0SerXaa: 0.0 ± 0.0
Thr
4.66ThrAla: 4.66 ± 2.104
1.332ThrCys: 1.332 ± 0.677
4.328ThrAsp: 4.328 ± 0.356
5.659ThrGlu: 5.659 ± 0.321
3.329ThrPhe: 3.329 ± 0.864
1.997ThrGly: 1.997 ± 0.902
2.996ThrHis: 2.996 ± 1.033
2.996ThrIle: 2.996 ± 1.033
2.663ThrLys: 2.663 ± 1.354
6.325ThrLeu: 6.325 ± 1.258
0.999ThrMet: 0.999 ± 0.77
4.328ThrAsn: 4.328 ± 2.913
3.329ThrPro: 3.329 ± 2.142
1.664ThrGln: 1.664 ± 0.432
2.33ThrArg: 2.33 ± 1.185
5.326ThrSer: 5.326 ± 1.766
7.324ThrThr: 7.324 ± 3.307
1.664ThrVal: 1.664 ± 0.207
0.333ThrTrp: 0.333 ± 0.169
1.997ThrTyr: 1.997 ± 0.902
0.0ThrXaa: 0.0 ± 0.0
Val
3.995ValAla: 3.995 ± 0.753
1.664ValCys: 1.664 ± 0.432
1.664ValAsp: 1.664 ± 0.846
2.663ValGlu: 2.663 ± 1.354
2.996ValPhe: 2.996 ± 0.245
4.993ValGly: 4.993 ± 0.018
0.333ValHis: 0.333 ± 0.169
3.995ValIle: 3.995 ± 0.114
5.326ValLys: 5.326 ± 2.069
4.66ValLeu: 4.66 ± 0.187
1.664ValMet: 1.664 ± 0.207
3.329ValAsn: 3.329 ± 0.864
6.325ValPro: 6.325 ± 2.536
1.332ValGln: 1.332 ± 0.038
2.33ValArg: 2.33 ± 0.733
5.992ValSer: 5.992 ± 0.49
4.993ValThr: 4.993 ± 0.018
5.326ValVal: 5.326 ± 0.488
0.999ValTrp: 0.999 ± 0.131
3.329ValTyr: 3.329 ± 1.053
0.0ValXaa: 0.0 ± 0.0
Trp
0.666TrpAla: 0.666 ± 0.338
0.0TrpCys: 0.0 ± 0.0
0.666TrpAsp: 0.666 ± 0.338
1.332TrpGlu: 1.332 ± 0.038
0.999TrpPhe: 0.999 ± 0.131
0.333TrpGly: 0.333 ± 0.47
0.0TrpHis: 0.0 ± 0.0
1.997TrpIle: 1.997 ± 0.376
0.666TrpLys: 0.666 ± 0.301
1.664TrpLeu: 1.664 ± 0.207
0.0TrpMet: 0.0 ± 0.0
0.666TrpAsn: 0.666 ± 0.301
0.666TrpPro: 0.666 ± 0.338
0.666TrpGln: 0.666 ± 0.338
1.664TrpArg: 1.664 ± 0.207
0.666TrpSer: 0.666 ± 0.301
0.333TrpThr: 0.333 ± 0.169
0.666TrpVal: 0.666 ± 0.94
0.0TrpTrp: 0.0 ± 0.0
0.333TrpTyr: 0.333 ± 0.169
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.996TyrAla: 2.996 ± 1.672
0.333TyrCys: 0.333 ± 0.169
2.996TyrAsp: 2.996 ± 0.394
1.664TyrGlu: 1.664 ± 1.071
2.663TyrPhe: 2.663 ± 1.354
1.997TyrGly: 1.997 ± 0.902
0.666TyrHis: 0.666 ± 0.338
3.995TyrIle: 3.995 ± 0.753
2.663TyrLys: 2.663 ± 0.715
3.329TyrLeu: 3.329 ± 1.053
1.332TyrMet: 1.332 ± 0.601
1.997TyrAsn: 1.997 ± 0.376
0.666TyrPro: 0.666 ± 0.338
1.332TyrGln: 1.332 ± 0.038
1.664TyrArg: 1.664 ± 0.207
2.996TyrSer: 2.996 ± 2.311
2.663TyrThr: 2.663 ± 1.202
3.662TyrVal: 3.662 ± 1.223
0.0TyrTrp: 0.0 ± 0.0
0.999TyrTyr: 0.999 ± 0.508
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (3005 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski