Amino acid dipepetide frequency for Ganoderma sinense ZZ0214-1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.225AlaAla: 10.225 ± 0.055	1.183AlaCys: 1.183 ± 0.014	4.714AlaAsp: 4.714 ± 0.028	5.121AlaGlu: 5.121 ± 0.035	3.573AlaPhe: 3.573 ± 0.022	5.929AlaGly: 5.929 ± 0.035	2.421AlaHis: 2.421 ± 0.022	4.071AlaIle: 4.071 ± 0.027	3.631AlaLys: 3.631 ± 0.028	9.159AlaLeu: 9.159 ± 0.044	2.038AlaMet: 2.038 ± 0.019	2.764AlaAsn: 2.764 ± 0.02	6.193AlaPro: 6.193 ± 0.043	3.454AlaGln: 3.454 ± 0.025	6.113AlaArg: 6.113 ± 0.037	8.075AlaSer: 8.075 ± 0.044	5.64AlaThr: 5.64 ± 0.033	6.016AlaVal: 6.016 ± 0.035	1.335AlaTrp: 1.335 ± 0.015	2.271AlaTyr: 2.271 ± 0.019	0.0AlaXaa: 0.0 ± 0.0
Cys	1.139CysAla: 1.139 ± 0.015	0.272CysCys: 0.272 ± 0.008	0.704CysAsp: 0.704 ± 0.012	0.612CysGlu: 0.612 ± 0.011	0.49CysPhe: 0.49 ± 0.008	0.991CysGly: 0.991 ± 0.013	0.329CysHis: 0.329 ± 0.007	0.614CysIle: 0.614 ± 0.009	0.474CysLys: 0.474 ± 0.008	1.158CysLeu: 1.158 ± 0.015	0.271CysMet: 0.271 ± 0.006	0.377CysAsn: 0.377 ± 0.008	0.892CysPro: 0.892 ± 0.014	0.407CysGln: 0.407 ± 0.008	0.85CysArg: 0.85 ± 0.011	0.927CysSer: 0.927 ± 0.013	0.761CysThr: 0.761 ± 0.012	0.838CysVal: 0.838 ± 0.012	0.19CysTrp: 0.19 ± 0.006	0.34CysTyr: 0.34 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	5.524AspAla: 5.524 ± 0.034	0.638AspCys: 0.638 ± 0.009	4.397AspAsp: 4.397 ± 0.038	4.323AspGlu: 4.323 ± 0.036	2.093AspPhe: 2.093 ± 0.018	4.406AspGly: 4.406 ± 0.028	1.284AspHis: 1.284 ± 0.015	2.778AspIle: 2.778 ± 0.022	2.022AspLys: 2.022 ± 0.02	5.061AspLeu: 5.061 ± 0.028	1.22AspMet: 1.22 ± 0.015	1.561AspAsn: 1.561 ± 0.017	3.812AspPro: 3.812 ± 0.022	1.536AspGln: 1.536 ± 0.016	3.127AspArg: 3.127 ± 0.028	4.055AspSer: 4.055 ± 0.026	2.946AspThr: 2.946 ± 0.022	4.369AspVal: 4.369 ± 0.026	0.931AspTrp: 0.931 ± 0.014	1.437AspTyr: 1.437 ± 0.015	0.0AspXaa: 0.0 ± 0.0
Glu	5.03GluAla: 5.03 ± 0.033	0.672GluCys: 0.672 ± 0.011	4.361GluAsp: 4.361 ± 0.036	5.154GluGlu: 5.154 ± 0.051	1.867GluPhe: 1.867 ± 0.018	3.812GluGly: 3.812 ± 0.024	1.518GluHis: 1.518 ± 0.015	2.418GluIle: 2.418 ± 0.022	2.707GluLys: 2.707 ± 0.026	5.37GluLeu: 5.37 ± 0.035	1.282GluMet: 1.282 ± 0.014	1.645GluAsn: 1.645 ± 0.016	2.895GluPro: 2.895 ± 0.024	2.078GluGln: 2.078 ± 0.02	4.199GluArg: 4.199 ± 0.034	3.762GluSer: 3.762 ± 0.025	2.905GluThr: 2.905 ± 0.021	3.715GluVal: 3.715 ± 0.027	0.964GluTrp: 0.964 ± 0.012	1.523GluTyr: 1.523 ± 0.015	0.0GluXaa: 0.0 ± 0.0
Phe	3.486PheAla: 3.486 ± 0.025	0.528PheCys: 0.528 ± 0.009	2.292PheAsp: 2.292 ± 0.019	1.95PheGlu: 1.95 ± 0.02	1.529PhePhe: 1.529 ± 0.017	2.632PheGly: 2.632 ± 0.024	0.945PheHis: 0.945 ± 0.012	1.576PheIle: 1.576 ± 0.017	1.373PheLys: 1.373 ± 0.016	3.471PheLeu: 3.471 ± 0.027	0.756PheMet: 0.756 ± 0.011	1.224PheAsn: 1.224 ± 0.014	2.282PhePro: 2.282 ± 0.022	1.193PheGln: 1.193 ± 0.014	2.123PheArg: 2.123 ± 0.02	3.015PheSer: 3.015 ± 0.025	2.134PheThr: 2.134 ± 0.018	2.672PheVal: 2.672 ± 0.024	0.599PheTrp: 0.599 ± 0.01	0.997PheTyr: 0.997 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	5.757GlyAla: 5.757 ± 0.034	0.893GlyCys: 0.893 ± 0.012	3.648GlyAsp: 3.648 ± 0.024	3.663GlyGlu: 3.663 ± 0.025	2.535GlyPhe: 2.535 ± 0.021	5.542GlyGly: 5.542 ± 0.047	1.75GlyHis: 1.75 ± 0.019	2.958GlyIle: 2.958 ± 0.02	3.039GlyLys: 3.039 ± 0.022	5.671GlyLeu: 5.671 ± 0.032	1.507GlyMet: 1.507 ± 0.019	2.029GlyAsn: 2.029 ± 0.018	3.846GlyPro: 3.846 ± 0.029	2.296GlyGln: 2.296 ± 0.022	4.384GlyArg: 4.384 ± 0.029	5.684GlySer: 5.684 ± 0.035	4.181GlyThr: 4.181 ± 0.028	4.427GlyVal: 4.427 ± 0.03	1.155GlyTrp: 1.155 ± 0.016	1.84GlyTyr: 1.84 ± 0.018	0.0GlyXaa: 0.0 ± 0.0
His	2.425HisAla: 2.425 ± 0.022	0.361HisCys: 0.361 ± 0.009	1.414HisAsp: 1.414 ± 0.016	1.285HisGlu: 1.285 ± 0.014	0.981HisPhe: 0.981 ± 0.012	1.793HisGly: 1.793 ± 0.018	0.879HisHis: 0.879 ± 0.014	1.272HisIle: 1.272 ± 0.016	0.889HisLys: 0.889 ± 0.013	2.691HisLeu: 2.691 ± 0.022	0.489HisMet: 0.489 ± 0.008	0.758HisAsn: 0.758 ± 0.01	2.137HisPro: 2.137 ± 0.018	0.865HisGln: 0.865 ± 0.013	1.744HisArg: 1.744 ± 0.019	2.045HisSer: 2.045 ± 0.024	1.488HisThr: 1.488 ± 0.015	1.783HisVal: 1.783 ± 0.017	0.386HisTrp: 0.386 ± 0.007	0.688HisTyr: 0.688 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	4.039IleAla: 4.039 ± 0.026	0.606IleCys: 0.606 ± 0.008	2.516IleAsp: 2.516 ± 0.019	2.308IleGlu: 2.308 ± 0.019	1.677IlePhe: 1.677 ± 0.017	2.668IleGly: 2.668 ± 0.025	1.129IleHis: 1.129 ± 0.014	1.946IleIle: 1.946 ± 0.023	1.595IleLys: 1.595 ± 0.017	4.047IleLeu: 4.047 ± 0.029	0.841IleMet: 0.841 ± 0.012	1.317IleAsn: 1.317 ± 0.014	3.189IlePro: 3.189 ± 0.022	1.535IleGln: 1.535 ± 0.015	2.655IleArg: 2.655 ± 0.02	3.233IleSer: 3.233 ± 0.024	2.454IleThr: 2.454 ± 0.022	3.085IleVal: 3.085 ± 0.025	0.643IleTrp: 0.643 ± 0.011	1.169IleTyr: 1.169 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	3.866LysAla: 3.866 ± 0.033	0.451LysCys: 0.451 ± 0.008	2.327LysAsp: 2.327 ± 0.02	2.666LysGlu: 2.666 ± 0.029	1.247LysPhe: 1.247 ± 0.015	2.634LysGly: 2.634 ± 0.023	1.047LysHis: 1.047 ± 0.014	1.611LysIle: 1.611 ± 0.018	2.508LysLys: 2.508 ± 0.032	3.617LysLeu: 3.617 ± 0.027	0.775LysMet: 0.775 ± 0.01	1.225LysAsn: 1.225 ± 0.013	2.407LysPro: 2.407 ± 0.02	1.388LysGln: 1.388 ± 0.017	3.093LysArg: 3.093 ± 0.028	2.587LysSer: 2.587 ± 0.024	2.326LysThr: 2.326 ± 0.018	2.463LysVal: 2.463 ± 0.02	0.584LysTrp: 0.584 ± 0.01	1.116LysTyr: 1.116 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	8.82LeuAla: 8.82 ± 0.042	1.257LeuCys: 1.257 ± 0.015	5.345LeuAsp: 5.345 ± 0.033	5.397LeuGlu: 5.397 ± 0.037	3.403LeuPhe: 3.403 ± 0.027	5.732LeuGly: 5.732 ± 0.033	2.663LeuHis: 2.663 ± 0.022	3.409LeuIle: 3.409 ± 0.027	3.597LeuLys: 3.597 ± 0.028	8.661LeuLeu: 8.661 ± 0.05	1.619LeuMet: 1.619 ± 0.019	2.8LeuAsn: 2.8 ± 0.023	6.77LeuPro: 6.77 ± 0.04	3.54LeuGln: 3.54 ± 0.024	6.66LeuArg: 6.66 ± 0.035	7.844LeuSer: 7.844 ± 0.042	5.252LeuThr: 5.252 ± 0.031	6.18LeuVal: 6.18 ± 0.032	1.263LeuTrp: 1.263 ± 0.015	2.298LeuTyr: 2.298 ± 0.019	0.0LeuXaa: 0.0 ± 0.0
Met	1.907MetAla: 1.907 ± 0.018	0.248MetCys: 0.248 ± 0.006	1.203MetAsp: 1.203 ± 0.015	1.086MetGlu: 1.086 ± 0.013	0.763MetPhe: 0.763 ± 0.01	1.244MetGly: 1.244 ± 0.018	0.544MetHis: 0.544 ± 0.009	0.766MetIle: 0.766 ± 0.012	0.793MetLys: 0.793 ± 0.011	1.862MetLeu: 1.862 ± 0.016	0.454MetMet: 0.454 ± 0.01	0.668MetAsn: 0.668 ± 0.011	1.384MetPro: 1.384 ± 0.015	0.763MetGln: 0.763 ± 0.012	1.321MetArg: 1.321 ± 0.014	1.934MetSer: 1.934 ± 0.019	1.142MetThr: 1.142 ± 0.014	1.22MetVal: 1.22 ± 0.015	0.274MetTrp: 0.274 ± 0.007	0.542MetTyr: 0.542 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.058AsnAla: 3.058 ± 0.022	0.372AsnCys: 0.372 ± 0.008	1.595AsnAsp: 1.595 ± 0.018	1.461AsnGlu: 1.461 ± 0.016	1.14AsnPhe: 1.14 ± 0.013	2.49AsnGly: 2.49 ± 0.023	0.721AsnHis: 0.721 ± 0.011	1.538AsnIle: 1.538 ± 0.017	1.096AsnLys: 1.096 ± 0.014	2.861AsnLeu: 2.861 ± 0.021	0.655AsnMet: 0.655 ± 0.012	1.023AsnAsn: 1.023 ± 0.014	2.189AsnPro: 2.189 ± 0.02	0.939AsnGln: 0.939 ± 0.013	1.587AsnArg: 1.587 ± 0.014	2.119AsnSer: 2.119 ± 0.019	1.795AsnThr: 1.795 ± 0.02	2.308AsnVal: 2.308 ± 0.019	0.456AsnTrp: 0.456 ± 0.009	0.8AsnTyr: 0.8 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	6.6ProAla: 6.6 ± 0.041	0.623ProCys: 0.623 ± 0.012	3.646ProAsp: 3.646 ± 0.028	3.968ProGlu: 3.968 ± 0.027	2.307ProPhe: 2.307 ± 0.019	4.293ProGly: 4.293 ± 0.034	1.869ProHis: 1.869 ± 0.019	2.633ProIle: 2.633 ± 0.02	2.375ProLys: 2.375 ± 0.021	5.696ProLeu: 5.696 ± 0.033	1.123ProMet: 1.123 ± 0.012	2.078ProAsn: 2.078 ± 0.019	7.483ProPro: 7.483 ± 0.07	2.577ProGln: 2.577 ± 0.029	4.272ProArg: 4.272 ± 0.034	7.718ProSer: 7.718 ± 0.059	4.684ProThr: 4.684 ± 0.036	4.271ProVal: 4.271 ± 0.03	0.784ProTrp: 0.784 ± 0.01	1.612ProTyr: 1.612 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	3.326GlnAla: 3.326 ± 0.027	0.454GlnCys: 0.454 ± 0.009	1.887GlnAsp: 1.887 ± 0.02	2.019GlnGlu: 2.019 ± 0.02	1.229GlnPhe: 1.229 ± 0.014	2.1GlnGly: 2.1 ± 0.019	1.052GlnHis: 1.052 ± 0.015	1.4GlnIle: 1.4 ± 0.015	1.404GlnLys: 1.404 ± 0.019	3.24GlnLeu: 3.24 ± 0.024	0.739GlnMet: 0.739 ± 0.01	1.114GlnAsn: 1.114 ± 0.015	2.533GlnPro: 2.533 ± 0.023	1.758GlnGln: 1.758 ± 0.03	2.459GlnArg: 2.459 ± 0.021	2.739GlnSer: 2.739 ± 0.026	2.036GlnThr: 2.036 ± 0.019	2.095GlnVal: 2.095 ± 0.015	0.569GlnTrp: 0.569 ± 0.01	1.048GlnTyr: 1.048 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	6.089ArgAla: 6.089 ± 0.035	0.856ArgCys: 0.856 ± 0.012	3.588ArgAsp: 3.588 ± 0.031	4.043ArgGlu: 4.043 ± 0.033	2.261ArgPhe: 2.261 ± 0.018	4.015ArgGly: 4.015 ± 0.028	1.738ArgHis: 1.738 ± 0.019	2.824ArgIle: 2.824 ± 0.022	3.115ArgLys: 3.115 ± 0.024	6.107ArgLeu: 6.107 ± 0.035	1.434ArgMet: 1.434 ± 0.014	1.895ArgAsn: 1.895 ± 0.016	4.192ArgPro: 4.192 ± 0.031	2.252ArgGln: 2.252 ± 0.02	5.764ArgArg: 5.764 ± 0.044	5.156ArgSer: 5.156 ± 0.039	3.853ArgThr: 3.853 ± 0.028	4.037ArgVal: 4.037 ± 0.027	1.091ArgTrp: 1.091 ± 0.011	1.702ArgTyr: 1.702 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	7.55SerAla: 7.55 ± 0.043	0.92SerCys: 0.92 ± 0.015	4.441SerAsp: 4.441 ± 0.031	3.979SerGlu: 3.979 ± 0.03	2.979SerPhe: 2.979 ± 0.024	5.676SerGly: 5.676 ± 0.035	2.059SerHis: 2.059 ± 0.021	3.43SerIle: 3.43 ± 0.025	2.966SerLys: 2.966 ± 0.021	7.582SerLeu: 7.582 ± 0.037	1.635SerMet: 1.635 ± 0.015	2.426SerAsn: 2.426 ± 0.022	6.64SerPro: 6.64 ± 0.056	2.933SerGln: 2.933 ± 0.024	5.258SerArg: 5.258 ± 0.036	9.659SerSer: 9.659 ± 0.07	5.847SerThr: 5.847 ± 0.04	5.065SerVal: 5.065 ± 0.033	1.088SerTrp: 1.088 ± 0.013	1.824SerTyr: 1.824 ± 0.016	0.0SerXaa: 0.0 ± 0.0
Thr	5.517ThrAla: 5.517 ± 0.035	0.78ThrCys: 0.78 ± 0.012	2.819ThrAsp: 2.819 ± 0.023	2.609ThrGlu: 2.609 ± 0.022	2.45ThrPhe: 2.45 ± 0.02	3.951ThrGly: 3.951 ± 0.026	1.531ThrHis: 1.531 ± 0.017	2.788ThrIle: 2.788 ± 0.024	2.057ThrLys: 2.057 ± 0.017	5.931ThrLeu: 5.931 ± 0.032	1.113ThrMet: 1.113 ± 0.012	1.807ThrAsn: 1.807 ± 0.018	4.758ThrPro: 4.758 ± 0.037	1.886ThrGln: 1.886 ± 0.017	3.501ThrArg: 3.501 ± 0.025	5.536ThrSer: 5.536 ± 0.043	4.255ThrThr: 4.255 ± 0.037	4.115ThrVal: 4.115 ± 0.025	0.818ThrTrp: 0.818 ± 0.011	1.547ThrTyr: 1.547 ± 0.014	0.0ThrXaa: 0.0 ± 0.0
Val	6.057ValAla: 6.057 ± 0.032	0.939ValCys: 0.939 ± 0.013	4.063ValAsp: 4.063 ± 0.025	4.014ValGlu: 4.014 ± 0.029	2.645ValPhe: 2.645 ± 0.023	4.084ValGly: 4.084 ± 0.029	1.775ValHis: 1.775 ± 0.018	2.75ValIle: 2.75 ± 0.021	2.62ValLys: 2.62 ± 0.022	6.488ValLeu: 6.488 ± 0.037	1.248ValMet: 1.248 ± 0.014	2.016ValAsn: 2.016 ± 0.019	4.643ValPro: 4.643 ± 0.03	2.407ValGln: 2.407 ± 0.021	4.175ValArg: 4.175 ± 0.026	4.98ValSer: 4.98 ± 0.029	3.601ValThr: 3.601 ± 0.023	5.018ValVal: 5.018 ± 0.04	1.043ValTrp: 1.043 ± 0.012	1.825ValTyr: 1.825 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	1.208TrpAla: 1.208 ± 0.013	0.2TrpCys: 0.2 ± 0.006	0.936TrpAsp: 0.936 ± 0.014	0.891TrpGlu: 0.891 ± 0.012	0.566TrpPhe: 0.566 ± 0.01	0.905TrpGly: 0.905 ± 0.012	0.392TrpHis: 0.392 ± 0.008	0.677TrpIle: 0.677 ± 0.009	0.741TrpLys: 0.741 ± 0.01	1.299TrpLeu: 1.299 ± 0.016	0.385TrpMet: 0.385 ± 0.007	0.572TrpAsn: 0.572 ± 0.01	0.749TrpPro: 0.749 ± 0.011	0.521TrpGln: 0.521 ± 0.009	1.152TrpArg: 1.152 ± 0.015	1.075TrpSer: 1.075 ± 0.012	0.947TrpThr: 0.947 ± 0.012	0.922TrpVal: 0.922 ± 0.013	0.296TrpTrp: 0.296 ± 0.007	0.437TrpTyr: 0.437 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.303TyrAla: 2.303 ± 0.018	0.385TyrCys: 0.385 ± 0.008	1.623TyrAsp: 1.623 ± 0.017	1.328TyrGlu: 1.328 ± 0.016	1.04TyrPhe: 1.04 ± 0.013	1.908TyrGly: 1.908 ± 0.02	0.726TyrHis: 0.726 ± 0.01	1.193TyrIle: 1.193 ± 0.014	0.94TyrLys: 0.94 ± 0.012	2.539TyrLeu: 2.539 ± 0.021	0.532TyrMet: 0.532 ± 0.008	0.906TyrAsn: 0.906 ± 0.014	1.615TyrPro: 1.615 ± 0.018	0.873TyrGln: 0.873 ± 0.011	1.577TyrArg: 1.577 ± 0.017	1.814TyrSer: 1.814 ± 0.017	1.523TyrThr: 1.523 ± 0.016	1.791TyrVal: 1.791 ± 0.017	0.401TyrTrp: 0.401 ± 0.008	0.82TyrTyr: 0.82 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.015XaaXaa: 0.015 ± 0.007

Statistics based on 15394 proteins (6730433 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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