Cyclovirus TN18

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Arfiviricetes; Cirlivirales; Circoviridae; Cyclovirus; Human associated cyclovirus 4

Average proteome isoelectric point is 8.61

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 2 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|D4N3R5|D4N3R5_9CIRC Capsid protein OS=Cyclovirus TN18 OX=742925 GN=cap PE=4 SV=1
MM1 pKa = 7.61AGSSSKK7 pKa = 8.08QTNSTLRR14 pKa = 11.84RR15 pKa = 11.84FCWTLNNYY23 pKa = 7.61TEE25 pKa = 4.37EE26 pKa = 5.04DD27 pKa = 3.87VTTLQKK33 pKa = 10.99DD34 pKa = 3.35LAEE37 pKa = 4.3LCKK40 pKa = 10.04FAIFGRR46 pKa = 11.84EE47 pKa = 3.79TCPNTGTKK55 pKa = 9.83HH56 pKa = 5.86LQGFCNLQRR65 pKa = 11.84PKK67 pKa = 10.38RR68 pKa = 11.84FSSIRR73 pKa = 11.84KK74 pKa = 8.26LFKK77 pKa = 10.37EE78 pKa = 3.8RR79 pKa = 11.84AHH81 pKa = 6.43IEE83 pKa = 3.96KK84 pKa = 10.77AKK86 pKa = 11.0GSDD89 pKa = 3.81LDD91 pKa = 3.76NKK93 pKa = 8.82TYY95 pKa = 10.26CSKK98 pKa = 10.93SGEE101 pKa = 4.13VWMHH105 pKa = 6.59GEE107 pKa = 4.11PCSQGARR114 pKa = 11.84NDD116 pKa = 3.59LQEE119 pKa = 4.17VVSVIEE125 pKa = 4.21GGEE128 pKa = 4.01RR129 pKa = 11.84NIKK132 pKa = 9.99AVALQFPTTYY142 pKa = 9.86IKK144 pKa = 10.48YY145 pKa = 10.24FKK147 pKa = 10.71GIEE150 pKa = 3.74QYY152 pKa = 10.81IRR154 pKa = 11.84ICHH157 pKa = 5.98SSAEE161 pKa = 4.27RR162 pKa = 11.84DD163 pKa = 3.29FATQVSFFWGPTGSGKK179 pKa = 8.81SRR181 pKa = 11.84RR182 pKa = 11.84AYY184 pKa = 10.1EE185 pKa = 3.79EE186 pKa = 3.89AKK188 pKa = 10.04ATGEE192 pKa = 4.01PIYY195 pKa = 10.23YY196 pKa = 9.93KK197 pKa = 10.49PRR199 pKa = 11.84GEE201 pKa = 3.89WWDD204 pKa = 4.58GYY206 pKa = 10.5CGHH209 pKa = 7.34ANVIIDD215 pKa = 5.69DD216 pKa = 4.49FYY218 pKa = 11.78GWLKK222 pKa = 10.72YY223 pKa = 10.67DD224 pKa = 4.31EE225 pKa = 4.82LLKK228 pKa = 10.7ICDD231 pKa = 3.7RR232 pKa = 11.84YY233 pKa = 10.06PYY235 pKa = 9.86RR236 pKa = 11.84VPVKK240 pKa = 10.11GGYY243 pKa = 9.57EE244 pKa = 3.82NFVTKK249 pKa = 10.4RR250 pKa = 11.84IWITSEE256 pKa = 3.85KK257 pKa = 9.9PLEE260 pKa = 3.98QIYY263 pKa = 10.37RR264 pKa = 11.84FIGYY268 pKa = 8.81DD269 pKa = 3.11CSSIRR274 pKa = 11.84RR275 pKa = 11.84RR276 pKa = 11.84LNTEE280 pKa = 4.07LYY282 pKa = 9.96IGYY285 pKa = 8.96QQ286 pKa = 3.15

Molecular weight: 33.2 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|D4N3R5|D4N3R5_9CIRC Capsid protein OS=Cyclovirus TN18 OX=742925 GN=cap PE=4 SV=1
MM1 pKa = 7.67AFRR4 pKa = 11.84RR5 pKa = 11.84RR6 pKa = 11.84VGRR9 pKa = 11.84SRR11 pKa = 11.84APIRR15 pKa = 11.84RR16 pKa = 11.84KK17 pKa = 9.68LPRR20 pKa = 11.84RR21 pKa = 11.84RR22 pKa = 11.84VARR25 pKa = 11.84RR26 pKa = 11.84RR27 pKa = 11.84RR28 pKa = 11.84FRR30 pKa = 11.84RR31 pKa = 11.84SRR33 pKa = 11.84RR34 pKa = 11.84LRR36 pKa = 11.84GNFTVLAKK44 pKa = 9.39RR45 pKa = 11.84TQVVVIQGDD54 pKa = 3.39EE55 pKa = 4.3GGTVTIAPSLNDD67 pKa = 3.49FTEE70 pKa = 4.49LAPLVPNFEE79 pKa = 4.5GFRR82 pKa = 11.84IWSVSCKK89 pKa = 9.6IRR91 pKa = 11.84PLFNVASDD99 pKa = 3.42VGPVPRR105 pKa = 11.84YY106 pKa = 9.65YY107 pKa = 10.33VAPWHH112 pKa = 6.69KK113 pKa = 8.47PTPTTVDD120 pKa = 3.37SNGVLSIDD128 pKa = 3.84RR129 pKa = 11.84SKK131 pKa = 11.25SYY133 pKa = 11.13NGTSGAFRR141 pKa = 11.84RR142 pKa = 11.84FVPALLSAVGYY153 pKa = 10.4SGIAGNQYY161 pKa = 10.94GKK163 pKa = 9.99IEE165 pKa = 3.73WRR167 pKa = 11.84PRR169 pKa = 11.84VEE171 pKa = 4.79LNSNTQSLQHH181 pKa = 5.61YY182 pKa = 8.88CGVVHH187 pKa = 6.96WSKK190 pKa = 11.26DD191 pKa = 3.51QLPGAGAPSRR201 pKa = 11.84RR202 pKa = 11.84QYY204 pKa = 10.68EE205 pKa = 3.74IEE207 pKa = 4.86LIAKK211 pKa = 7.61ITLYY215 pKa = 8.74NQKK218 pKa = 10.26YY219 pKa = 10.06FIGG222 pKa = 3.96

Molecular weight: 25.23 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

2

0

2

508

222

286

254.0

29.22

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.709 ± 0.675

2.362 ± 0.941

3.543 ± 0.541

5.709 ± 1.646

4.724 ± 0.142

8.071 ± 0.024

1.575 ± 0.144

6.102 ± 0.449

6.102 ± 1.319

6.299 ± 0.295

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

0.591 ± 0.09

4.134 ± 0.239

4.921 ± 1.182

3.74 ± 0.088

10.039 ± 2.238

7.087 ± 0.368

5.709 ± 0.485

6.102 ± 1.872

2.165 ± 0.234

5.315 ± 0.812
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski