Amino acid dipepetide frequency for Luteibacter sp. UNCMF366Tsu5.1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.678AlaAla: 16.678 ± 0.178	1.148AlaCys: 1.148 ± 0.036	7.124AlaAsp: 7.124 ± 0.078	6.628AlaGlu: 6.628 ± 0.094	4.445AlaPhe: 4.445 ± 0.061	10.111AlaGly: 10.111 ± 0.133	2.764AlaHis: 2.764 ± 0.047	5.672AlaIle: 5.672 ± 0.078	3.886AlaLys: 3.886 ± 0.087	13.919AlaLeu: 13.919 ± 0.13	3.481AlaMet: 3.481 ± 0.064	3.148AlaAsn: 3.148 ± 0.057	6.09AlaPro: 6.09 ± 0.086	4.426AlaGln: 4.426 ± 0.063	8.888AlaArg: 8.888 ± 0.11	7.45AlaSer: 7.45 ± 0.099	6.953AlaThr: 6.953 ± 0.095	8.954AlaVal: 8.954 ± 0.114	2.072AlaTrp: 2.072 ± 0.044	2.692AlaTyr: 2.692 ± 0.053	0.0AlaXaa: 0.0 ± 0.0
Cys	0.926CysAla: 0.926 ± 0.028	0.084CysCys: 0.084 ± 0.008	0.452CysAsp: 0.452 ± 0.02	0.392CysGlu: 0.392 ± 0.017	0.281CysPhe: 0.281 ± 0.016	0.782CysGly: 0.782 ± 0.027	0.224CysHis: 0.224 ± 0.015	0.311CysIle: 0.311 ± 0.017	0.178CysLys: 0.178 ± 0.013	0.788CysLeu: 0.788 ± 0.028	0.165CysMet: 0.165 ± 0.01	0.167CysAsn: 0.167 ± 0.011	0.34CysPro: 0.34 ± 0.019	0.202CysGln: 0.202 ± 0.011	0.523CysArg: 0.523 ± 0.021	0.403CysSer: 0.403 ± 0.019	0.406CysThr: 0.406 ± 0.018	0.677CysVal: 0.677 ± 0.027	0.101CysTrp: 0.101 ± 0.01	0.22CysTyr: 0.22 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	8.65AspAla: 8.65 ± 0.105	0.372AspCys: 0.372 ± 0.02	4.027AspAsp: 4.027 ± 0.071	3.625AspGlu: 3.625 ± 0.067	2.128AspPhe: 2.128 ± 0.051	5.909AspGly: 5.909 ± 0.093	1.331AspHis: 1.331 ± 0.029	2.721AspIle: 2.721 ± 0.047	1.605AspLys: 1.605 ± 0.046	5.83AspLeu: 5.83 ± 0.067	1.252AspMet: 1.252 ± 0.03	1.372AspAsn: 1.372 ± 0.037	3.436AspPro: 3.436 ± 0.055	1.654AspGln: 1.654 ± 0.041	4.193AspArg: 4.193 ± 0.066	2.43AspSer: 2.43 ± 0.046	3.255AspThr: 3.255 ± 0.051	4.956AspVal: 4.956 ± 0.065	0.993AspTrp: 0.993 ± 0.032	1.616AspTyr: 1.616 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	6.84GluAla: 6.84 ± 0.091	0.352GluCys: 0.352 ± 0.018	2.496GluAsp: 2.496 ± 0.048	2.393GluGlu: 2.393 ± 0.055	1.58GluPhe: 1.58 ± 0.041	4.234GluGly: 4.234 ± 0.065	1.52GluHis: 1.52 ± 0.035	2.243GluIle: 2.243 ± 0.048	1.731GluLys: 1.731 ± 0.042	5.41GluLeu: 5.41 ± 0.087	1.0GluMet: 1.0 ± 0.031	1.334GluAsn: 1.334 ± 0.036	2.508GluPro: 2.508 ± 0.053	2.121GluGln: 2.121 ± 0.047	5.215GluArg: 5.215 ± 0.087	2.478GluSer: 2.478 ± 0.046	2.729GluThr: 2.729 ± 0.044	3.68GluVal: 3.68 ± 0.07	0.698GluTrp: 0.698 ± 0.026	1.082GluTyr: 1.082 ± 0.03	0.0GluXaa: 0.0 ± 0.0
Phe	4.516PheAla: 4.516 ± 0.076	0.306PheCys: 0.306 ± 0.015	2.79PheAsp: 2.79 ± 0.043	1.886PheGlu: 1.886 ± 0.039	1.303PhePhe: 1.303 ± 0.042	3.405PheGly: 3.405 ± 0.059	0.802PheHis: 0.802 ± 0.029	1.325PheIle: 1.325 ± 0.033	0.869PheLys: 0.869 ± 0.03	2.987PheLeu: 2.987 ± 0.054	0.684PheMet: 0.684 ± 0.024	1.054PheAsn: 1.054 ± 0.035	1.547PhePro: 1.547 ± 0.035	0.983PheGln: 0.983 ± 0.025	2.3PheArg: 2.3 ± 0.05	1.969PheSer: 1.969 ± 0.037	1.905PheThr: 1.905 ± 0.043	2.916PheVal: 2.916 ± 0.05	0.481PheTrp: 0.481 ± 0.021	0.852PheTyr: 0.852 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	9.07GlyAla: 9.07 ± 0.133	0.77GlyCys: 0.77 ± 0.026	5.018GlyAsp: 5.018 ± 0.07	4.52GlyGlu: 4.52 ± 0.07	3.302GlyPhe: 3.302 ± 0.05	7.266GlyGly: 7.266 ± 0.14	2.13GlyHis: 2.13 ± 0.042	4.149GlyIle: 4.149 ± 0.065	3.339GlyLys: 3.339 ± 0.059	8.024GlyLeu: 8.024 ± 0.101	2.354GlyMet: 2.354 ± 0.046	2.567GlyAsn: 2.567 ± 0.074	3.153GlyPro: 3.153 ± 0.052	2.882GlyGln: 2.882 ± 0.05	5.885GlyArg: 5.885 ± 0.073	4.94GlySer: 4.94 ± 0.086	4.989GlyThr: 4.989 ± 0.104	6.622GlyVal: 6.622 ± 0.09	1.525GlyTrp: 1.525 ± 0.037	2.6GlyTyr: 2.6 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	3.239HisAla: 3.239 ± 0.053	0.198HisCys: 0.198 ± 0.013	1.54HisAsp: 1.54 ± 0.043	1.203HisGlu: 1.203 ± 0.037	0.915HisPhe: 0.915 ± 0.029	2.39HisGly: 2.39 ± 0.05	0.615HisHis: 0.615 ± 0.027	0.876HisIle: 0.876 ± 0.027	0.47HisLys: 0.47 ± 0.02	2.173HisLeu: 2.173 ± 0.041	0.528HisMet: 0.528 ± 0.022	0.468HisAsn: 0.468 ± 0.019	1.566HisPro: 1.566 ± 0.036	0.59HisGln: 0.59 ± 0.02	1.691HisArg: 1.691 ± 0.042	1.031HisSer: 1.031 ± 0.027	1.12HisThr: 1.12 ± 0.032	1.904HisVal: 1.904 ± 0.042	0.434HisTrp: 0.434 ± 0.02	0.684HisTyr: 0.684 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	6.284IleAla: 6.284 ± 0.079	0.342IleCys: 0.342 ± 0.016	3.599IleAsp: 3.599 ± 0.065	2.941IleGlu: 2.941 ± 0.052	1.233IlePhe: 1.233 ± 0.029	4.326IleGly: 4.326 ± 0.064	0.948IleHis: 0.948 ± 0.029	1.285IleIle: 1.285 ± 0.039	1.113IleLys: 1.113 ± 0.031	3.26IleLeu: 3.26 ± 0.058	0.627IleMet: 0.627 ± 0.022	1.205IleAsn: 1.205 ± 0.039	2.042IlePro: 2.042 ± 0.042	1.135IleGln: 1.135 ± 0.035	2.759IleArg: 2.759 ± 0.046	2.091IleSer: 2.091 ± 0.046	2.233IleThr: 2.233 ± 0.051	3.989IleVal: 3.989 ± 0.059	0.453IleTrp: 0.453 ± 0.02	0.945IleTyr: 0.945 ± 0.031	0.0IleXaa: 0.0 ± 0.0
Lys	3.856LysAla: 3.856 ± 0.062	0.123LysCys: 0.123 ± 0.01	1.694LysAsp: 1.694 ± 0.041	1.314LysGlu: 1.314 ± 0.04	0.704LysPhe: 0.704 ± 0.027	2.362LysGly: 2.362 ± 0.046	0.678LysHis: 0.678 ± 0.025	1.213LysIle: 1.213 ± 0.043	1.142LysLys: 1.142 ± 0.046	2.93LysLeu: 2.93 ± 0.057	0.607LysMet: 0.607 ± 0.023	0.808LysAsn: 0.808 ± 0.03	1.983LysPro: 1.983 ± 0.041	1.121LysGln: 1.121 ± 0.036	2.252LysArg: 2.252 ± 0.051	1.572LysSer: 1.572 ± 0.039	1.704LysThr: 1.704 ± 0.036	2.355LysVal: 2.355 ± 0.051	0.297LysTrp: 0.297 ± 0.014	0.635LysTyr: 0.635 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	14.252LeuAla: 14.252 ± 0.137	0.854LeuCys: 0.854 ± 0.031	6.813LeuAsp: 6.813 ± 0.096	4.648LeuGlu: 4.648 ± 0.074	3.309LeuPhe: 3.309 ± 0.062	8.586LeuGly: 8.586 ± 0.086	2.301LeuHis: 2.301 ± 0.051	4.012LeuIle: 4.012 ± 0.062	3.05LeuLys: 3.05 ± 0.062	10.295LeuLeu: 10.295 ± 0.116	2.024LeuMet: 2.024 ± 0.041	2.352LeuAsn: 2.352 ± 0.051	6.227LeuPro: 6.227 ± 0.073	2.752LeuGln: 2.752 ± 0.051	8.03LeuArg: 8.03 ± 0.11	5.878LeuSer: 5.878 ± 0.07	5.335LeuThr: 5.335 ± 0.073	7.75LeuVal: 7.75 ± 0.09	1.278LeuTrp: 1.278 ± 0.036	2.074LeuTyr: 2.074 ± 0.04	0.0LeuXaa: 0.0 ± 0.0
Met	2.792MetAla: 2.792 ± 0.051	0.141MetCys: 0.141 ± 0.012	1.176MetAsp: 1.176 ± 0.033	0.988MetGlu: 0.988 ± 0.031	0.644MetPhe: 0.644 ± 0.025	1.575MetGly: 1.575 ± 0.039	0.595MetHis: 0.595 ± 0.025	0.948MetIle: 0.948 ± 0.024	0.832MetLys: 0.832 ± 0.03	2.425MetLeu: 2.425 ± 0.048	0.418MetMet: 0.418 ± 0.02	0.754MetAsn: 0.754 ± 0.025	1.451MetPro: 1.451 ± 0.039	0.831MetGln: 0.831 ± 0.025	1.895MetArg: 1.895 ± 0.037	1.564MetSer: 1.564 ± 0.033	1.459MetThr: 1.459 ± 0.033	1.522MetVal: 1.522 ± 0.037	0.195MetTrp: 0.195 ± 0.013	0.403MetTyr: 0.403 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.383AsnAla: 3.383 ± 0.06	0.17AsnCys: 0.17 ± 0.011	1.673AsnAsp: 1.673 ± 0.044	1.335AsnGlu: 1.335 ± 0.038	0.86AsnPhe: 0.86 ± 0.025	2.652AsnGly: 2.652 ± 0.067	0.581AsnHis: 0.581 ± 0.022	1.055AsnIle: 1.055 ± 0.031	0.644AsnLys: 0.644 ± 0.025	2.593AsnLeu: 2.593 ± 0.053	0.444AsnMet: 0.444 ± 0.021	0.737AsnAsn: 0.737 ± 0.031	1.649AsnPro: 1.649 ± 0.04	0.795AsnGln: 0.795 ± 0.032	1.671AsnArg: 1.671 ± 0.038	1.073AsnSer: 1.073 ± 0.039	1.413AsnThr: 1.413 ± 0.046	2.196AsnVal: 2.196 ± 0.047	0.372AsnTrp: 0.372 ± 0.016	0.756AsnTyr: 0.756 ± 0.028	0.0AsnXaa: 0.0 ± 0.0
Pro	6.518ProAla: 6.518 ± 0.1	0.317ProCys: 0.317 ± 0.015	3.592ProAsp: 3.592 ± 0.053	3.107ProGlu: 3.107 ± 0.056	1.811ProPhe: 1.811 ± 0.038	4.689ProGly: 4.689 ± 0.063	1.129ProHis: 1.129 ± 0.033	2.05ProIle: 2.05 ± 0.042	1.527ProLys: 1.527 ± 0.039	5.13ProLeu: 5.13 ± 0.07	1.384ProMet: 1.384 ± 0.032	1.32ProAsn: 1.32 ± 0.035	2.884ProPro: 2.884 ± 0.065	1.647ProGln: 1.647 ± 0.04	3.386ProArg: 3.386 ± 0.056	3.264ProSer: 3.264 ± 0.054	2.833ProThr: 2.833 ± 0.05	4.25ProVal: 4.25 ± 0.057	0.89ProTrp: 0.89 ± 0.028	1.239ProTyr: 1.239 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	4.452GlnAla: 4.452 ± 0.064	0.205GlnCys: 0.205 ± 0.014	1.538GlnAsp: 1.538 ± 0.041	1.248GlnGlu: 1.248 ± 0.039	1.063GlnPhe: 1.063 ± 0.037	2.661GlnGly: 2.661 ± 0.047	0.774GlnHis: 0.774 ± 0.025	1.415GlnIle: 1.415 ± 0.037	0.931GlnLys: 0.931 ± 0.031	3.21GlnLeu: 3.21 ± 0.054	0.731GlnMet: 0.731 ± 0.026	0.791GlnAsn: 0.791 ± 0.028	1.868GlnPro: 1.868 ± 0.047	1.453GlnGln: 1.453 ± 0.044	2.977GlnArg: 2.977 ± 0.049	1.664GlnSer: 1.664 ± 0.041	1.598GlnThr: 1.598 ± 0.045	2.641GlnVal: 2.641 ± 0.05	0.533GlnTrp: 0.533 ± 0.022	0.799GlnTyr: 0.799 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	7.923ArgAla: 7.923 ± 0.093	0.506ArgCys: 0.506 ± 0.024	4.577ArgAsp: 4.577 ± 0.073	4.551ArgGlu: 4.551 ± 0.077	3.042ArgPhe: 3.042 ± 0.047	5.123ArgGly: 5.123 ± 0.072	2.076ArgHis: 2.076 ± 0.044	3.632ArgIle: 3.632 ± 0.071	2.045ArgLys: 2.045 ± 0.049	8.278ArgLeu: 8.278 ± 0.111	2.009ArgMet: 2.009 ± 0.039	1.819ArgAsn: 1.819 ± 0.034	3.465ArgPro: 3.465 ± 0.06	2.707ArgGln: 2.707 ± 0.054	6.127ArgArg: 6.127 ± 0.093	3.825ArgSer: 3.825 ± 0.058	3.695ArgThr: 3.695 ± 0.064	5.422ArgVal: 5.422 ± 0.072	1.333ArgTrp: 1.333 ± 0.035	2.193ArgTyr: 2.193 ± 0.051	0.0ArgXaa: 0.0 ± 0.0
Ser	6.515SerAla: 6.515 ± 0.09	0.376SerCys: 0.376 ± 0.017	3.011SerAsp: 3.011 ± 0.053	2.486SerGlu: 2.486 ± 0.042	2.075SerPhe: 2.075 ± 0.047	5.117SerGly: 5.117 ± 0.092	1.244SerHis: 1.244 ± 0.031	2.496SerIle: 2.496 ± 0.052	1.416SerLys: 1.416 ± 0.036	5.822SerLeu: 5.822 ± 0.073	1.33SerMet: 1.33 ± 0.031	1.439SerAsn: 1.439 ± 0.037	3.035SerPro: 3.035 ± 0.049	1.681SerGln: 1.681 ± 0.037	3.894SerArg: 3.894 ± 0.057	3.212SerSer: 3.212 ± 0.072	3.145SerThr: 3.145 ± 0.057	4.039SerVal: 4.039 ± 0.067	0.835SerTrp: 0.835 ± 0.025	1.427SerTyr: 1.427 ± 0.036	0.0SerXaa: 0.0 ± 0.0
Thr	6.189ThrAla: 6.189 ± 0.089	0.41ThrCys: 0.41 ± 0.018	3.029ThrAsp: 3.029 ± 0.057	2.358ThrGlu: 2.358 ± 0.047	2.002ThrPhe: 2.002 ± 0.041	4.845ThrGly: 4.845 ± 0.089	1.299ThrHis: 1.299 ± 0.035	2.406ThrIle: 2.406 ± 0.055	1.356ThrLys: 1.356 ± 0.039	6.386ThrLeu: 6.386 ± 0.096	1.088ThrMet: 1.088 ± 0.031	1.323ThrAsn: 1.323 ± 0.045	3.625ThrPro: 3.625 ± 0.06	1.802ThrGln: 1.802 ± 0.047	3.682ThrArg: 3.682 ± 0.052	3.005ThrSer: 3.005 ± 0.056	3.114ThrThr: 3.114 ± 0.07	4.525ThrVal: 4.525 ± 0.07	0.857ThrTrp: 0.857 ± 0.028	1.427ThrTyr: 1.427 ± 0.044	0.0ThrXaa: 0.0 ± 0.0
Val	10.154ValAla: 10.154 ± 0.107	0.626ValCys: 0.626 ± 0.025	4.888ValAsp: 4.888 ± 0.062	4.255ValGlu: 4.255 ± 0.066	2.687ValPhe: 2.687 ± 0.043	5.935ValGly: 5.935 ± 0.084	1.664ValHis: 1.664 ± 0.038	3.438ValIle: 3.438 ± 0.063	2.056ValLys: 2.056 ± 0.05	7.941ValLeu: 7.941 ± 0.086	1.617ValMet: 1.617 ± 0.035	2.195ValAsn: 2.195 ± 0.054	4.174ValPro: 4.174 ± 0.061	2.263ValGln: 2.263 ± 0.042	5.609ValArg: 5.609 ± 0.072	4.626ValSer: 4.626 ± 0.073	4.63ValThr: 4.63 ± 0.073	6.575ValVal: 6.575 ± 0.096	0.963ValTrp: 0.963 ± 0.026	1.672ValTyr: 1.672 ± 0.035	0.0ValXaa: 0.0 ± 0.0
Trp	1.273TrpAla: 1.273 ± 0.03	0.138TrpCys: 0.138 ± 0.01	0.705TrpAsp: 0.705 ± 0.024	0.557TrpGlu: 0.557 ± 0.027	0.582TrpPhe: 0.582 ± 0.022	0.869TrpGly: 0.869 ± 0.027	0.437TrpHis: 0.437 ± 0.018	0.715TrpIle: 0.715 ± 0.024	0.51TrpLys: 0.51 ± 0.021	1.989TrpLeu: 1.989 ± 0.046	0.43TrpMet: 0.43 ± 0.017	0.552TrpAsn: 0.552 ± 0.019	0.723TrpPro: 0.723 ± 0.023	0.693TrpGln: 0.693 ± 0.025	1.355TrpArg: 1.355 ± 0.033	0.919TrpSer: 0.919 ± 0.03	0.866TrpThr: 0.866 ± 0.025	0.987TrpVal: 0.987 ± 0.027	0.293TrpTrp: 0.293 ± 0.017	0.407TrpTyr: 0.407 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.02TyrAla: 3.02 ± 0.052	0.184TyrCys: 0.184 ± 0.012	1.612TyrAsp: 1.612 ± 0.053	1.209TyrGlu: 1.209 ± 0.03	0.912TyrPhe: 0.912 ± 0.029	2.271TyrGly: 2.271 ± 0.045	0.525TyrHis: 0.525 ± 0.02	0.848TyrIle: 0.848 ± 0.027	0.651TyrLys: 0.651 ± 0.024	2.429TyrLeu: 2.429 ± 0.049	0.436TyrMet: 0.436 ± 0.02	0.647TyrAsn: 0.647 ± 0.029	1.202TyrPro: 1.202 ± 0.032	0.815TyrGln: 0.815 ± 0.027	2.014TyrArg: 2.014 ± 0.045	1.201TyrSer: 1.201 ± 0.034	1.346TyrThr: 1.346 ± 0.04	2.007TyrVal: 2.007 ± 0.036	0.395TyrTrp: 0.395 ± 0.018	0.701TyrTyr: 0.701 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3582 proteins (1261826 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---