Human papillomavirus 172

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Gammapapillomavirus; Gammapapillomavirus 22

Average proteome isoelectric point is 5.93

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|V5W3W0|V5W3W0_9PAPI Major capsid protein L1 OS=Human papillomavirus 172 OX=1434987 GN=L1 PE=3 SV=1
MM1 pKa = 7.9RR2 pKa = 11.84GPAPRR7 pKa = 11.84AGDD10 pKa = 3.21IEE12 pKa = 5.04LEE14 pKa = 4.3LEE16 pKa = 4.62SLVLPQNLLSNEE28 pKa = 4.11SLSPDD33 pKa = 3.34TEE35 pKa = 4.31GQPEE39 pKa = 4.19EE40 pKa = 4.51VEE42 pKa = 4.1QVPYY46 pKa = 10.68KK47 pKa = 10.79VDD49 pKa = 3.49TCCWACGAGVRR60 pKa = 11.84LCVVASRR67 pKa = 11.84LSILTFEE74 pKa = 4.16QLLIGEE80 pKa = 5.21LSLLCPPCSKK90 pKa = 10.15IYY92 pKa = 10.2CRR94 pKa = 11.84NGRR97 pKa = 11.84QQ98 pKa = 3.0

Molecular weight: 10.72 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|V5W3V7|V5W3V7_9PAPI Protein E7 OS=Human papillomavirus 172 OX=1434987 GN=E7 PE=3 SV=1
MM1 pKa = 7.03NQADD5 pKa = 4.02LTSRR9 pKa = 11.84FDD11 pKa = 3.63VLQEE15 pKa = 3.88NLMNLYY21 pKa = 10.44EE22 pKa = 4.88SDD24 pKa = 4.0PKK26 pKa = 11.02TIDD29 pKa = 3.24AQIKK33 pKa = 7.55IWEE36 pKa = 4.74IIRR39 pKa = 11.84KK40 pKa = 9.29QYY42 pKa = 9.64VLYY45 pKa = 10.62YY46 pKa = 9.03YY47 pKa = 10.5GRR49 pKa = 11.84KK50 pKa = 9.34EE51 pKa = 3.74GFRR54 pKa = 11.84NFGLQPLPVTSVSEE68 pKa = 4.27YY69 pKa = 9.68KK70 pKa = 10.68AKK72 pKa = 10.52EE73 pKa = 4.15AIQQVLLLKK82 pKa = 10.25SLKK85 pKa = 10.16DD86 pKa = 3.38SPYY89 pKa = 10.97GSEE92 pKa = 3.75EE93 pKa = 3.61WTLTDD98 pKa = 3.42TSAEE102 pKa = 4.18LTHH105 pKa = 6.15TAPRR109 pKa = 11.84NAFKK113 pKa = 10.67KK114 pKa = 9.12QAYY117 pKa = 5.77TVEE120 pKa = 4.55VYY122 pKa = 10.6FDD124 pKa = 4.51HH125 pKa = 6.88NPKK128 pKa = 10.61NSFPYY133 pKa = 10.29TNWKK137 pKa = 8.2WLYY140 pKa = 10.62LQDD143 pKa = 5.04EE144 pKa = 4.2NDD146 pKa = 3.33MWYY149 pKa = 10.33KK150 pKa = 10.96APGLVDD156 pKa = 3.92VNGLYY161 pKa = 10.64YY162 pKa = 10.25EE163 pKa = 5.18DD164 pKa = 3.48KK165 pKa = 11.11HH166 pKa = 7.93GDD168 pKa = 3.05KK169 pKa = 11.07NYY171 pKa = 10.27FVIFASDD178 pKa = 3.37AYY180 pKa = 9.63TYY182 pKa = 8.41GTTGEE187 pKa = 4.26WTVHH191 pKa = 5.59FNNEE195 pKa = 3.99YY196 pKa = 9.21MSSVPASTSQDD207 pKa = 3.26TFSGSLQGSNKK218 pKa = 9.94GSVSSSKK225 pKa = 10.79DD226 pKa = 3.34AVPVPQTPRR235 pKa = 11.84RR236 pKa = 11.84QKK238 pKa = 10.9GEE240 pKa = 3.87EE241 pKa = 4.23GGASSTTATPPSLRR255 pKa = 11.84RR256 pKa = 11.84RR257 pKa = 11.84RR258 pKa = 11.84RR259 pKa = 11.84RR260 pKa = 11.84AQQGEE265 pKa = 4.35RR266 pKa = 11.84TTTRR270 pKa = 11.84PKK272 pKa = 10.27RR273 pKa = 11.84RR274 pKa = 11.84RR275 pKa = 11.84LEE277 pKa = 3.94EE278 pKa = 4.47DD279 pKa = 3.31VSSTSPGEE287 pKa = 4.36VGSGTHH293 pKa = 5.25LVSRR297 pKa = 11.84RR298 pKa = 11.84GLTRR302 pKa = 11.84LEE304 pKa = 3.93RR305 pKa = 11.84LKK307 pKa = 11.3AEE309 pKa = 4.08ARR311 pKa = 11.84DD312 pKa = 3.81PFVLLVTGASNSLKK326 pKa = 9.21CWRR329 pKa = 11.84YY330 pKa = 9.15RR331 pKa = 11.84VKK333 pKa = 10.53KK334 pKa = 8.84SQASVVCISTVFSWTGLHH352 pKa = 7.18VNDD355 pKa = 4.76CDD357 pKa = 4.63KK358 pKa = 10.96NHH360 pKa = 6.65KK361 pKa = 9.19MLLAFNSANQRR372 pKa = 11.84QHH374 pKa = 6.78FIEE377 pKa = 4.41TVPFPKK383 pKa = 10.38GASYY387 pKa = 9.85TLGNLNALL395 pKa = 4.07

Molecular weight: 44.9 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2448

98

600

349.7

39.61

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.025 ± 0.29

2.819 ± 1.047

6.781 ± 0.681

6.087 ± 0.335

4.779 ± 0.664

5.31 ± 0.555

1.716 ± 0.222

5.882 ± 1.181

5.637 ± 0.911

8.497 ± 1.141

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.389 ± 0.26

5.065 ± 0.301

6.577 ± 1.037

3.922 ± 0.397

5.433 ± 0.493

7.149 ± 0.904

6.944 ± 0.867

5.964 ± 0.862

1.348 ± 0.232

3.676 ± 0.689
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski