Amino acid dipepetide frequency for Frondihabitans australicus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
20.022AlaAla: 20.022 ± 0.207
0.666AlaCys: 0.666 ± 0.026
7.858AlaAsp: 7.858 ± 0.093
6.847AlaGlu: 6.847 ± 0.1
4.027AlaPhe: 4.027 ± 0.065
12.344AlaGly: 12.344 ± 0.115
2.315AlaHis: 2.315 ± 0.045
5.763AlaIle: 5.763 ± 0.075
2.79AlaLys: 2.79 ± 0.058
13.756AlaLeu: 13.756 ± 0.149
2.582AlaMet: 2.582 ± 0.045
2.411AlaAsn: 2.411 ± 0.045
6.803AlaPro: 6.803 ± 0.116
3.753AlaGln: 3.753 ± 0.063
8.561AlaArg: 8.561 ± 0.101
8.706AlaSer: 8.706 ± 0.094
8.69AlaThr: 8.69 ± 0.11
11.334AlaVal: 11.334 ± 0.134
1.789AlaTrp: 1.789 ± 0.044
2.393AlaTyr: 2.393 ± 0.045
0.0AlaXaa: 0.0 ± 0.0
Cys
0.579CysAla: 0.579 ± 0.023
0.043CysCys: 0.043 ± 0.006
0.296CysAsp: 0.296 ± 0.016
0.223CysGlu: 0.223 ± 0.014
0.165CysPhe: 0.165 ± 0.01
0.512CysGly: 0.512 ± 0.023
0.097CysHis: 0.097 ± 0.009
0.184CysIle: 0.184 ± 0.013
0.061CysLys: 0.061 ± 0.007
0.474CysLeu: 0.474 ± 0.018
0.078CysMet: 0.078 ± 0.008
0.1CysAsn: 0.1 ± 0.008
0.236CysPro: 0.236 ± 0.014
0.116CysGln: 0.116 ± 0.011
0.273CysArg: 0.273 ± 0.017
0.361CysSer: 0.361 ± 0.016
0.348CysThr: 0.348 ± 0.019
0.416CysVal: 0.416 ± 0.019
0.065CysTrp: 0.065 ± 0.007
0.101CysTyr: 0.101 ± 0.01
0.0CysXaa: 0.0 ± 0.0
Asp
7.906AspAla: 7.906 ± 0.078
0.211AspCys: 0.211 ± 0.013
4.941AspAsp: 4.941 ± 0.081
4.377AspGlu: 4.377 ± 0.069
1.834AspPhe: 1.834 ± 0.042
5.838AspGly: 5.838 ± 0.079
1.26AspHis: 1.26 ± 0.033
2.205AspIle: 2.205 ± 0.049
0.885AspLys: 0.885 ± 0.031
6.446AspLeu: 6.446 ± 0.088
0.756AspMet: 0.756 ± 0.027
0.932AspAsn: 0.932 ± 0.03
3.994AspPro: 3.994 ± 0.067
1.513AspGln: 1.513 ± 0.034
4.303AspArg: 4.303 ± 0.071
3.153AspSer: 3.153 ± 0.058
3.202AspThr: 3.202 ± 0.055
5.506AspVal: 5.506 ± 0.072
0.932AspTrp: 0.932 ± 0.032
1.293AspTyr: 1.293 ± 0.033
0.0AspXaa: 0.0 ± 0.0
Glu
6.812GluAla: 6.812 ± 0.115
0.185GluCys: 0.185 ± 0.013
1.77GluAsp: 1.77 ± 0.045
2.139GluGlu: 2.139 ± 0.051
1.684GluPhe: 1.684 ± 0.04
3.756GluGly: 3.756 ± 0.062
1.347GluHis: 1.347 ± 0.037
2.525GluIle: 2.525 ± 0.05
1.439GluLys: 1.439 ± 0.036
5.57GluLeu: 5.57 ± 0.087
0.898GluMet: 0.898 ± 0.027
1.113GluAsn: 1.113 ± 0.031
2.817GluPro: 2.817 ± 0.049
1.868GluGln: 1.868 ± 0.045
4.429GluArg: 4.429 ± 0.071
3.152GluSer: 3.152 ± 0.053
3.121GluThr: 3.121 ± 0.056
4.178GluVal: 4.178 ± 0.069
0.827GluTrp: 0.827 ± 0.03
1.016GluTyr: 1.016 ± 0.028
0.0GluXaa: 0.0 ± 0.0
Phe
4.24PheAla: 4.24 ± 0.069
0.198PheCys: 0.198 ± 0.013
2.525PheAsp: 2.525 ± 0.048
1.738PheGlu: 1.738 ± 0.045
1.161PhePhe: 1.161 ± 0.034
3.519PheGly: 3.519 ± 0.054
0.577PheHis: 0.577 ± 0.021
1.101PheIle: 1.101 ± 0.032
0.456PheLys: 0.456 ± 0.023
2.821PheLeu: 2.821 ± 0.053
0.461PheMet: 0.461 ± 0.021
0.622PheAsn: 0.622 ± 0.024
1.393PhePro: 1.393 ± 0.038
0.788PheGln: 0.788 ± 0.023
1.886PheArg: 1.886 ± 0.04
1.949PheSer: 1.949 ± 0.041
2.274PheThr: 2.274 ± 0.048
3.113PheVal: 3.113 ± 0.052
0.48PheTrp: 0.48 ± 0.021
0.692PheTyr: 0.692 ± 0.029
0.0PheXaa: 0.0 ± 0.0
Gly
11.145GlyAla: 11.145 ± 0.103
0.507GlyCys: 0.507 ± 0.022
5.309GlyAsp: 5.309 ± 0.074
4.203GlyGlu: 4.203 ± 0.066
3.391GlyPhe: 3.391 ± 0.054
7.804GlyGly: 7.804 ± 0.098
1.921GlyHis: 1.921 ± 0.039
4.426GlyIle: 4.426 ± 0.071
2.002GlyLys: 2.002 ± 0.04
9.261GlyLeu: 9.261 ± 0.099
1.643GlyMet: 1.643 ± 0.035
1.703GlyAsn: 1.703 ± 0.048
3.84GlyPro: 3.84 ± 0.056
2.543GlyGln: 2.543 ± 0.05
6.407GlyArg: 6.407 ± 0.089
6.52GlySer: 6.52 ± 0.091
6.006GlyThr: 6.006 ± 0.107
8.253GlyVal: 8.253 ± 0.089
1.474GlyTrp: 1.474 ± 0.037
2.252GlyTyr: 2.252 ± 0.046
0.0GlyXaa: 0.0 ± 0.0
His
2.269HisAla: 2.269 ± 0.042
0.096HisCys: 0.096 ± 0.01
1.488HisAsp: 1.488 ± 0.04
1.105HisGlu: 1.105 ± 0.03
0.604HisPhe: 0.604 ± 0.025
1.983HisGly: 1.983 ± 0.05
0.489HisHis: 0.489 ± 0.022
0.652HisIle: 0.652 ± 0.023
0.226HisLys: 0.226 ± 0.014
2.059HisLeu: 2.059 ± 0.047
0.277HisMet: 0.277 ± 0.016
0.338HisAsn: 0.338 ± 0.019
1.395HisPro: 1.395 ± 0.034
0.47HisGln: 0.47 ± 0.02
1.572HisArg: 1.572 ± 0.038
1.054HisSer: 1.054 ± 0.031
1.011HisThr: 1.011 ± 0.032
1.751HisVal: 1.751 ± 0.041
0.269HisTrp: 0.269 ± 0.016
0.44HisTyr: 0.44 ± 0.018
0.0HisXaa: 0.0 ± 0.0
Ile
6.367IleAla: 6.367 ± 0.076
0.22IleCys: 0.22 ± 0.015
3.264IleAsp: 3.264 ± 0.056
2.493IleGlu: 2.493 ± 0.049
1.077IlePhe: 1.077 ± 0.033
4.373IleGly: 4.373 ± 0.069
0.682IleHis: 0.682 ± 0.026
1.533IleIle: 1.533 ± 0.046
0.784IleLys: 0.784 ± 0.025
3.858IleLeu: 3.858 ± 0.06
0.571IleMet: 0.571 ± 0.026
0.881IleAsn: 0.881 ± 0.028
2.142IlePro: 2.142 ± 0.05
0.973IleGln: 0.973 ± 0.032
2.672IleArg: 2.672 ± 0.054
2.424IleSer: 2.424 ± 0.048
2.92IleThr: 2.92 ± 0.049
4.675IleVal: 4.675 ± 0.068
0.46IleTrp: 0.46 ± 0.018
0.66IleTyr: 0.66 ± 0.023
0.0IleXaa: 0.0 ± 0.0
Lys
2.793LysAla: 2.793 ± 0.055
0.072LysCys: 0.072 ± 0.007
0.991LysAsp: 0.991 ± 0.032
0.832LysGlu: 0.832 ± 0.026
0.502LysPhe: 0.502 ± 0.024
1.707LysGly: 1.707 ± 0.045
0.434LysHis: 0.434 ± 0.018
0.926LysIle: 0.926 ± 0.028
0.881LysLys: 0.881 ± 0.035
1.797LysLeu: 1.797 ± 0.041
0.398LysMet: 0.398 ± 0.018
0.669LysAsn: 0.669 ± 0.028
1.262LysPro: 1.262 ± 0.037
0.782LysGln: 0.782 ± 0.028
1.433LysArg: 1.433 ± 0.032
1.366LysSer: 1.366 ± 0.039
1.55LysThr: 1.55 ± 0.038
1.695LysVal: 1.695 ± 0.041
0.258LysTrp: 0.258 ± 0.014
0.514LysTyr: 0.514 ± 0.022
0.0LysXaa: 0.0 ± 0.0
Leu
14.23LeuAla: 14.23 ± 0.128
0.498LeuCys: 0.498 ± 0.021
6.831LeuAsp: 6.831 ± 0.095
4.979LeuGlu: 4.979 ± 0.074
2.898LeuPhe: 2.898 ± 0.058
9.249LeuGly: 9.249 ± 0.097
1.855LeuHis: 1.855 ± 0.041
3.919LeuIle: 3.919 ± 0.064
1.861LeuLys: 1.861 ± 0.044
9.767LeuLeu: 9.767 ± 0.115
1.522LeuMet: 1.522 ± 0.04
1.756LeuAsn: 1.756 ± 0.043
5.607LeuPro: 5.607 ± 0.073
2.431LeuGln: 2.431 ± 0.047
7.113LeuArg: 7.113 ± 0.084
5.889LeuSer: 5.889 ± 0.079
6.335LeuThr: 6.335 ± 0.073
9.665LeuVal: 9.665 ± 0.112
1.269LeuTrp: 1.269 ± 0.038
1.751LeuTyr: 1.751 ± 0.04
0.0LeuXaa: 0.0 ± 0.0
Met
2.091MetAla: 2.091 ± 0.041
0.091MetCys: 0.091 ± 0.008
0.694MetAsp: 0.694 ± 0.023
0.585MetGlu: 0.585 ± 0.023
0.482MetPhe: 0.482 ± 0.02
1.139MetGly: 1.139 ± 0.031
0.325MetHis: 0.325 ± 0.015
0.82MetIle: 0.82 ± 0.028
0.469MetLys: 0.469 ± 0.021
1.645MetLeu: 1.645 ± 0.039
0.287MetMet: 0.287 ± 0.016
0.474MetAsn: 0.474 ± 0.018
1.101MetPro: 1.101 ± 0.029
0.485MetGln: 0.485 ± 0.021
1.175MetArg: 1.175 ± 0.034
1.499MetSer: 1.499 ± 0.038
1.757MetThr: 1.757 ± 0.039
1.229MetVal: 1.229 ± 0.031
0.166MetTrp: 0.166 ± 0.011
0.273MetTyr: 0.273 ± 0.014
0.0MetXaa: 0.0 ± 0.0
Asn
2.45AsnAla: 2.45 ± 0.05
0.102AsnCys: 0.102 ± 0.01
1.196AsnAsp: 1.196 ± 0.037
0.881AsnGlu: 0.881 ± 0.029
0.638AsnPhe: 0.638 ± 0.026
2.071AsnGly: 2.071 ± 0.057
0.372AsnHis: 0.372 ± 0.018
0.805AsnIle: 0.805 ± 0.024
0.395AsnLys: 0.395 ± 0.02
1.928AsnLeu: 1.928 ± 0.045
0.34AsnMet: 0.34 ± 0.02
0.479AsnAsn: 0.479 ± 0.023
1.495AsnPro: 1.495 ± 0.032
0.591AsnGln: 0.591 ± 0.024
1.313AsnArg: 1.313 ± 0.032
1.173AsnSer: 1.173 ± 0.038
1.239AsnThr: 1.239 ± 0.042
1.738AsnVal: 1.738 ± 0.039
0.301AsnTrp: 0.301 ± 0.014
0.532AsnTyr: 0.532 ± 0.025
0.0AsnXaa: 0.0 ± 0.0
Pro
7.72ProAla: 7.72 ± 0.119
0.172ProCys: 0.172 ± 0.013
3.691ProAsp: 3.691 ± 0.06
3.301ProGlu: 3.301 ± 0.06
1.687ProPhe: 1.687 ± 0.037
5.1ProGly: 5.1 ± 0.069
1.086ProHis: 1.086 ± 0.031
2.096ProIle: 2.096 ± 0.041
1.129ProLys: 1.129 ± 0.034
4.834ProLeu: 4.834 ± 0.071
0.816ProMet: 0.816 ± 0.026
1.102ProAsn: 1.102 ± 0.032
2.123ProPro: 2.123 ± 0.058
1.46ProGln: 1.46 ± 0.034
3.316ProArg: 3.316 ± 0.06
3.754ProSer: 3.754 ± 0.054
3.753ProThr: 3.753 ± 0.071
4.767ProVal: 4.767 ± 0.076
0.806ProTrp: 0.806 ± 0.028
1.074ProTyr: 1.074 ± 0.029
0.0ProXaa: 0.0 ± 0.0
Gln
3.579GlnAla: 3.579 ± 0.057
0.112GlnCys: 0.112 ± 0.011
1.224GlnAsp: 1.224 ± 0.03
1.386GlnGlu: 1.386 ± 0.034
0.851GlnPhe: 0.851 ± 0.032
2.253GlnGly: 2.253 ± 0.044
0.59GlnHis: 0.59 ± 0.023
1.391GlnIle: 1.391 ± 0.042
0.792GlnLys: 0.792 ± 0.029
2.811GlnLeu: 2.811 ± 0.051
0.518GlnMet: 0.518 ± 0.024
0.69GlnAsn: 0.69 ± 0.028
1.524GlnPro: 1.524 ± 0.045
1.171GlnGln: 1.171 ± 0.045
2.082GlnArg: 2.082 ± 0.041
1.715GlnSer: 1.715 ± 0.043
1.799GlnThr: 1.799 ± 0.046
2.273GlnVal: 2.273 ± 0.051
0.414GlnTrp: 0.414 ± 0.018
0.667GlnTyr: 0.667 ± 0.025
0.0GlnXaa: 0.0 ± 0.0
Arg
8.546ArgAla: 8.546 ± 0.107
0.233ArgCys: 0.233 ± 0.015
4.303ArgAsp: 4.303 ± 0.07
3.863ArgGlu: 3.863 ± 0.068
2.372ArgPhe: 2.372 ± 0.049
5.256ArgGly: 5.256 ± 0.075
1.542ArgHis: 1.542 ± 0.036
3.473ArgIle: 3.473 ± 0.053
1.215ArgLys: 1.215 ± 0.034
7.35ArgLeu: 7.35 ± 0.089
1.458ArgMet: 1.458 ± 0.037
1.173ArgAsn: 1.173 ± 0.035
3.691ArgPro: 3.691 ± 0.063
2.066ArgGln: 2.066 ± 0.044
6.62ArgArg: 6.62 ± 0.104
4.191ArgSer: 4.191 ± 0.063
3.901ArgThr: 3.901 ± 0.057
5.794ArgVal: 5.794 ± 0.082
1.06ArgTrp: 1.06 ± 0.03
1.522ArgTyr: 1.522 ± 0.034
0.0ArgXaa: 0.0 ± 0.0
Ser
8.067SerAla: 8.067 ± 0.081
0.325SerCys: 0.325 ± 0.018
3.564SerAsp: 3.564 ± 0.062
2.619SerGlu: 2.619 ± 0.051
2.143SerPhe: 2.143 ± 0.047
6.529SerGly: 6.529 ± 0.083
1.26SerHis: 1.26 ± 0.034
2.863SerIle: 2.863 ± 0.051
1.484SerLys: 1.484 ± 0.044
6.139SerLeu: 6.139 ± 0.077
1.217SerMet: 1.217 ± 0.03
1.443SerAsn: 1.443 ± 0.042
3.546SerPro: 3.546 ± 0.056
1.784SerGln: 1.784 ± 0.043
4.349SerArg: 4.349 ± 0.064
4.812SerSer: 4.812 ± 0.109
4.877SerThr: 4.877 ± 0.088
5.191SerVal: 5.191 ± 0.064
1.04SerTrp: 1.04 ± 0.029
1.337SerTyr: 1.337 ± 0.037
0.0SerXaa: 0.0 ± 0.0
Thr
8.468ThrAla: 8.468 ± 0.108
0.323ThrCys: 0.323 ± 0.016
3.512ThrAsp: 3.512 ± 0.059
2.711ThrGlu: 2.711 ± 0.052
2.108ThrPhe: 2.108 ± 0.046
6.612ThrGly: 6.612 ± 0.105
1.175ThrHis: 1.175 ± 0.03
3.002ThrIle: 3.002 ± 0.065
1.442ThrLys: 1.442 ± 0.036
6.509ThrLeu: 6.509 ± 0.083
0.998ThrMet: 0.998 ± 0.026
1.376ThrAsn: 1.376 ± 0.044
4.334ThrPro: 4.334 ± 0.068
1.634ThrGln: 1.634 ± 0.044
3.896ThrArg: 3.896 ± 0.068
4.595ThrSer: 4.595 ± 0.096
5.003ThrThr: 5.003 ± 0.106
6.316ThrVal: 6.316 ± 0.114
1.003ThrTrp: 1.003 ± 0.026
1.419ThrTyr: 1.419 ± 0.04
0.0ThrXaa: 0.0 ± 0.0
Val
12.132ValAla: 12.132 ± 0.134
0.456ValCys: 0.456 ± 0.021
6.009ValAsp: 6.009 ± 0.076
4.714ValGlu: 4.714 ± 0.068
3.055ValPhe: 3.055 ± 0.057
7.437ValGly: 7.437 ± 0.095
1.592ValHis: 1.592 ± 0.038
4.087ValIle: 4.087 ± 0.059
1.814ValLys: 1.814 ± 0.042
8.642ValLeu: 8.642 ± 0.096
1.428ValMet: 1.428 ± 0.034
1.835ValAsn: 1.835 ± 0.042
4.732ValPro: 4.732 ± 0.07
2.237ValGln: 2.237 ± 0.047
5.451ValArg: 5.451 ± 0.083
5.888ValSer: 5.888 ± 0.079
6.411ValThr: 6.411 ± 0.101
9.665ValVal: 9.665 ± 0.118
1.146ValTrp: 1.146 ± 0.033
1.643ValTyr: 1.643 ± 0.037
0.0ValXaa: 0.0 ± 0.0
Trp
1.56TrpAla: 1.56 ± 0.035
0.091TrpCys: 0.091 ± 0.008
0.615TrpAsp: 0.615 ± 0.025
0.56TrpGlu: 0.56 ± 0.023
0.566TrpPhe: 0.566 ± 0.022
1.096TrpGly: 1.096 ± 0.033
0.32TrpHis: 0.32 ± 0.016
0.648TrpIle: 0.648 ± 0.023
0.362TrpLys: 0.362 ± 0.016
1.627TrpLeu: 1.627 ± 0.042
0.294TrpMet: 0.294 ± 0.015
0.436TrpAsn: 0.436 ± 0.021
0.726TrpPro: 0.726 ± 0.025
0.575TrpGln: 0.575 ± 0.026
1.213TrpArg: 1.213 ± 0.037
1.109TrpSer: 1.109 ± 0.033
0.891TrpThr: 0.891 ± 0.026
1.099TrpVal: 1.099 ± 0.031
0.316TrpTrp: 0.316 ± 0.016
0.296TrpTyr: 0.296 ± 0.017
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.436TyrAla: 2.436 ± 0.043
0.128TyrCys: 0.128 ± 0.01
1.409TyrAsp: 1.409 ± 0.038
1.089TyrGlu: 1.089 ± 0.035
0.75TyrPhe: 0.75 ± 0.028
2.031TyrGly: 2.031 ± 0.051
0.309TyrHis: 0.309 ± 0.016
0.61TyrIle: 0.61 ± 0.025
0.377TyrLys: 0.377 ± 0.02
2.13TyrLeu: 2.13 ± 0.038
0.245TyrMet: 0.245 ± 0.015
0.509TyrAsn: 0.509 ± 0.023
1.027TyrPro: 1.027 ± 0.03
0.601TyrGln: 0.601 ± 0.026
1.565TyrArg: 1.565 ± 0.038
1.278TyrSer: 1.278 ± 0.037
1.346TyrThr: 1.346 ± 0.043
1.713TyrVal: 1.713 ± 0.036
0.324TyrTrp: 0.324 ± 0.017
0.5TyrTyr: 0.5 ± 0.023
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3787 proteins (1213946 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski