Amino acid dipepetide frequency for Shahe picorna-like virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.12AlaAla: 3.12 ± 1.004
0.0AlaCys: 0.0 ± 0.0
5.07AlaAsp: 5.07 ± 1.402
3.9AlaGlu: 3.9 ± 1.407
4.29AlaPhe: 4.29 ± 0.837
3.51AlaGly: 3.51 ± 1.852
1.95AlaHis: 1.95 ± 0.214
3.51AlaIle: 3.51 ± 1.205
1.95AlaLys: 1.95 ± 0.398
5.85AlaLeu: 5.85 ± 0.641
1.17AlaMet: 1.17 ± 0.247
3.12AlaAsn: 3.12 ± 0.219
1.95AlaPro: 1.95 ± 0.214
2.34AlaGln: 2.34 ± 1.846
1.95AlaArg: 1.95 ± 0.214
4.29AlaSer: 4.29 ± 1.448
4.29AlaThr: 4.29 ± 2.06
6.24AlaVal: 6.24 ± 0.173
0.78AlaTrp: 0.78 ± 0.208
1.17AlaTyr: 1.17 ± 0.006
0.0AlaXaa: 0.0 ± 0.0
Cys
0.78CysAla: 0.78 ± 0.404
0.78CysCys: 0.78 ± 0.404
0.78CysAsp: 0.78 ± 0.404
0.39CysGlu: 0.39 ± 0.202
0.39CysPhe: 0.39 ± 0.202
1.17CysGly: 1.17 ± 0.606
0.39CysHis: 0.39 ± 0.202
0.78CysIle: 0.78 ± 0.208
0.78CysLys: 0.78 ± 0.208
1.17CysLeu: 1.17 ± 0.006
0.39CysMet: 0.39 ± 0.202
2.34CysAsn: 2.34 ± 0.012
1.17CysPro: 1.17 ± 0.606
0.39CysGln: 0.39 ± 0.41
1.95CysArg: 1.95 ± 1.009
0.78CysSer: 0.78 ± 0.208
0.78CysThr: 0.78 ± 0.404
1.95CysVal: 1.95 ± 1.437
0.39CysTrp: 0.39 ± 0.202
0.39CysTyr: 0.39 ± 0.41
0.0CysXaa: 0.0 ± 0.0
Asp
2.73AspAla: 2.73 ± 0.421
1.17AspCys: 1.17 ± 0.006
5.07AspAsp: 5.07 ± 0.79
4.29AspGlu: 4.29 ± 0.998
3.9AspPhe: 3.9 ± 0.796
2.73AspGly: 2.73 ± 1.413
0.0AspHis: 0.0 ± 0.0
4.29AspIle: 4.29 ± 0.998
1.17AspLys: 1.17 ± 0.006
6.63AspLeu: 6.63 ± 0.848
3.51AspMet: 3.51 ± 0.594
1.95AspAsn: 1.95 ± 0.214
4.29AspPro: 4.29 ± 2.671
0.39AspGln: 0.39 ± 0.41
1.95AspArg: 1.95 ± 0.398
3.12AspSer: 3.12 ± 0.219
5.85AspThr: 5.85 ± 0.029
3.51AspVal: 3.51 ± 0.018
0.78AspTrp: 0.78 ± 0.208
3.51AspTyr: 3.51 ± 0.629
0.0AspXaa: 0.0 ± 0.0
Glu
2.34GluAla: 2.34 ± 0.012
1.17GluCys: 1.17 ± 0.606
3.51GluAsp: 3.51 ± 1.205
4.29GluGlu: 4.29 ± 1.609
1.56GluPhe: 1.56 ± 0.415
0.78GluGly: 0.78 ± 0.404
1.17GluHis: 1.17 ± 0.606
3.51GluIle: 3.51 ± 0.018
3.9GluLys: 3.9 ± 2.019
4.68GluLeu: 4.68 ± 0.023
1.56GluMet: 1.56 ± 0.196
1.56GluAsn: 1.56 ± 0.415
2.34GluPro: 2.34 ± 0.012
4.29GluGln: 4.29 ± 0.998
3.9GluArg: 3.9 ± 0.796
1.95GluSer: 1.95 ± 0.398
4.29GluThr: 4.29 ± 0.837
3.9GluVal: 3.9 ± 1.039
0.78GluTrp: 0.78 ± 0.404
2.34GluTyr: 2.34 ± 0.012
0.0GluXaa: 0.0 ± 0.0
Phe
2.34PheAla: 2.34 ± 0.012
1.95PheCys: 1.95 ± 0.214
1.17PheAsp: 1.17 ± 0.006
1.95PheGlu: 1.95 ± 0.214
1.56PhePhe: 1.56 ± 0.808
3.9PheGly: 3.9 ± 1.65
1.95PheHis: 1.95 ± 0.214
3.51PheIle: 3.51 ± 1.205
2.73PheLys: 2.73 ± 0.802
2.73PheLeu: 2.73 ± 0.19
1.56PheMet: 1.56 ± 0.415
1.95PheAsn: 1.95 ± 0.398
2.73PhePro: 2.73 ± 1.033
1.56PheGln: 1.56 ± 0.415
1.95PheArg: 1.95 ± 0.398
3.51PheSer: 3.51 ± 0.018
3.51PheThr: 3.51 ± 1.241
5.07PheVal: 5.07 ± 1.402
0.0PheTrp: 0.0 ± 0.0
2.73PheTyr: 2.73 ± 0.19
0.0PheXaa: 0.0 ± 0.0
Gly
2.34GlyAla: 2.34 ± 1.846
0.78GlyCys: 0.78 ± 0.819
3.9GlyAsp: 3.9 ± 0.427
1.56GlyGlu: 1.56 ± 1.638
3.9GlyPhe: 3.9 ± 0.796
4.68GlyGly: 4.68 ± 0.635
1.56GlyHis: 1.56 ± 0.808
4.29GlyIle: 4.29 ± 0.998
3.12GlyLys: 3.12 ± 0.219
2.73GlyLeu: 2.73 ± 1.033
1.56GlyMet: 1.56 ± 0.196
3.51GlyAsn: 3.51 ± 0.594
2.73GlyPro: 2.73 ± 0.421
1.17GlyGln: 1.17 ± 0.006
3.51GlyArg: 3.51 ± 0.018
3.12GlySer: 3.12 ± 0.831
3.51GlyThr: 3.51 ± 0.018
5.07GlyVal: 5.07 ± 0.79
1.17GlyTrp: 1.17 ± 0.006
3.12GlyTyr: 3.12 ± 0.392
0.0GlyXaa: 0.0 ± 0.0
His
1.17HisAla: 1.17 ± 0.606
0.0HisCys: 0.0 ± 0.0
0.78HisAsp: 0.78 ± 0.404
0.39HisGlu: 0.39 ± 0.202
1.95HisPhe: 1.95 ± 0.398
1.56HisGly: 1.56 ± 0.196
0.0HisHis: 0.0 ± 0.0
1.95HisIle: 1.95 ± 0.398
1.56HisLys: 1.56 ± 0.196
1.56HisLeu: 1.56 ± 0.196
0.39HisMet: 0.39 ± 0.202
2.73HisAsn: 2.73 ± 0.19
0.78HisPro: 0.78 ± 0.208
0.0HisGln: 0.0 ± 0.0
1.95HisArg: 1.95 ± 1.009
1.17HisSer: 1.17 ± 0.606
1.56HisThr: 1.56 ± 0.415
3.9HisVal: 3.9 ± 0.796
0.39HisTrp: 0.39 ± 0.41
0.39HisTyr: 0.39 ± 0.41
0.0HisXaa: 0.0 ± 0.0
Ile
5.85IleAla: 5.85 ± 0.029
1.56IleCys: 1.56 ± 0.196
4.29IleAsp: 4.29 ± 0.386
3.51IleGlu: 3.51 ± 1.205
1.95IlePhe: 1.95 ± 1.009
4.29IleGly: 4.29 ± 0.225
1.95IleHis: 1.95 ± 0.398
1.95IleIle: 1.95 ± 0.398
3.9IleLys: 3.9 ± 0.796
5.07IleLeu: 5.07 ± 2.013
1.17IleMet: 1.17 ± 0.006
1.56IleAsn: 1.56 ± 0.196
1.56IlePro: 1.56 ± 0.196
2.73IleGln: 2.73 ± 0.19
5.46IleArg: 5.46 ± 0.992
3.12IleSer: 3.12 ± 0.219
5.07IleThr: 5.07 ± 0.179
2.34IleVal: 2.34 ± 0.012
1.95IleTrp: 1.95 ± 1.009
3.12IleTyr: 3.12 ± 1.615
0.0IleXaa: 0.0 ± 0.0
Lys
2.73LysAla: 2.73 ± 0.802
0.78LysCys: 0.78 ± 0.404
3.9LysAsp: 3.9 ± 0.184
2.34LysGlu: 2.34 ± 0.6
1.56LysPhe: 1.56 ± 1.027
2.34LysGly: 2.34 ± 0.012
1.17LysHis: 1.17 ± 0.006
3.12LysIle: 3.12 ± 1.004
3.51LysLys: 3.51 ± 1.205
3.51LysLeu: 3.51 ± 0.629
0.78LysMet: 0.78 ± 0.404
1.95LysAsn: 1.95 ± 0.214
4.29LysPro: 4.29 ± 0.225
2.34LysGln: 2.34 ± 0.6
3.51LysArg: 3.51 ± 0.018
4.29LysSer: 4.29 ± 1.609
2.34LysThr: 2.34 ± 0.6
3.9LysVal: 3.9 ± 0.796
0.0LysTrp: 0.0 ± 0.0
2.73LysTyr: 2.73 ± 0.802
0.0LysXaa: 0.0 ± 0.0
Leu
6.63LeuAla: 6.63 ± 1.46
1.17LeuCys: 1.17 ± 0.606
6.24LeuAsp: 6.24 ± 0.439
4.29LeuGlu: 4.29 ± 0.837
3.12LeuPhe: 3.12 ± 0.392
4.29LeuGly: 4.29 ± 0.386
3.51LeuHis: 3.51 ± 0.018
5.85LeuIle: 5.85 ± 1.805
3.9LeuLys: 3.9 ± 1.039
5.46LeuLeu: 5.46 ± 0.38
1.95LeuMet: 1.95 ± 0.398
3.9LeuAsn: 3.9 ± 0.184
4.29LeuPro: 4.29 ± 0.837
1.56LeuGln: 1.56 ± 0.196
3.12LeuArg: 3.12 ± 0.219
7.41LeuSer: 7.41 ± 1.668
5.07LeuThr: 5.07 ± 0.433
7.41LeuVal: 7.41 ± 0.167
1.56LeuTrp: 1.56 ± 0.415
4.68LeuTyr: 4.68 ± 1.2
0.0LeuXaa: 0.0 ± 0.0
Met
1.17MetAla: 1.17 ± 0.606
0.78MetCys: 0.78 ± 0.404
0.78MetAsp: 0.78 ± 0.819
1.95MetGlu: 1.95 ± 1.009
0.78MetPhe: 0.78 ± 0.208
0.39MetGly: 0.39 ± 0.202
2.34MetHis: 2.34 ± 0.012
1.56MetIle: 1.56 ± 0.808
1.17MetLys: 1.17 ± 0.006
1.56MetLeu: 1.56 ± 0.196
0.78MetMet: 0.78 ± 0.404
1.17MetAsn: 1.17 ± 0.617
1.17MetPro: 1.17 ± 0.606
1.17MetGln: 1.17 ± 0.006
1.56MetArg: 1.56 ± 0.196
3.12MetSer: 3.12 ± 1.004
0.78MetThr: 0.78 ± 0.208
1.56MetVal: 1.56 ± 0.415
0.0MetTrp: 0.0 ± 0.0
1.56MetTyr: 1.56 ± 0.415
0.0MetXaa: 0.0 ± 0.0
Asn
2.34AsnAla: 2.34 ± 0.6
1.17AsnCys: 1.17 ± 0.006
3.9AsnAsp: 3.9 ± 0.796
0.39AsnGlu: 0.39 ± 0.202
5.46AsnPhe: 5.46 ± 0.231
4.68AsnGly: 4.68 ± 1.858
0.78AsnHis: 0.78 ± 0.208
1.95AsnIle: 1.95 ± 0.398
2.34AsnLys: 2.34 ± 0.012
3.12AsnLeu: 3.12 ± 1.004
1.17AsnMet: 1.17 ± 0.006
1.56AsnAsn: 1.56 ± 0.196
2.34AsnPro: 2.34 ± 0.623
1.17AsnGln: 1.17 ± 0.606
1.56AsnArg: 1.56 ± 0.196
3.12AsnSer: 3.12 ± 0.392
2.34AsnThr: 2.34 ± 0.623
2.73AsnVal: 2.73 ± 0.421
1.95AsnTrp: 1.95 ± 0.398
1.56AsnTyr: 1.56 ± 1.027
0.0AsnXaa: 0.0 ± 0.0
Pro
2.73ProAla: 2.73 ± 1.033
0.39ProCys: 0.39 ± 0.41
4.29ProAsp: 4.29 ± 1.448
2.73ProGlu: 2.73 ± 0.19
3.51ProPhe: 3.51 ± 1.241
3.12ProGly: 3.12 ± 0.219
0.0ProHis: 0.0 ± 0.0
2.34ProIle: 2.34 ± 0.623
2.34ProLys: 2.34 ± 0.623
6.63ProLeu: 6.63 ± 2.071
1.56ProMet: 1.56 ± 0.415
1.95ProAsn: 1.95 ± 0.825
2.73ProPro: 2.73 ± 1.033
0.39ProGln: 0.39 ± 0.202
1.17ProArg: 1.17 ± 0.006
1.95ProSer: 1.95 ± 0.214
3.9ProThr: 3.9 ± 1.65
3.51ProVal: 3.51 ± 1.852
0.0ProTrp: 0.0 ± 0.0
3.12ProTyr: 3.12 ± 1.442
0.0ProXaa: 0.0 ± 0.0
Gln
1.95GlnAla: 1.95 ± 1.009
0.39GlnCys: 0.39 ± 0.202
0.39GlnAsp: 0.39 ± 0.41
1.56GlnGlu: 1.56 ± 0.196
0.78GlnPhe: 0.78 ± 0.404
1.56GlnGly: 1.56 ± 0.808
1.56GlnHis: 1.56 ± 0.196
1.17GlnIle: 1.17 ± 0.617
0.78GlnLys: 0.78 ± 0.404
3.51GlnLeu: 3.51 ± 0.629
0.0GlnMet: 0.0 ± 0.0
1.56GlnAsn: 1.56 ± 1.027
1.56GlnPro: 1.56 ± 0.415
1.56GlnGln: 1.56 ± 0.415
2.73GlnArg: 2.73 ± 0.19
2.34GlnSer: 2.34 ± 0.012
2.34GlnThr: 2.34 ± 0.012
0.78GlnVal: 0.78 ± 0.208
0.0GlnTrp: 0.0 ± 0.0
1.95GlnTyr: 1.95 ± 0.398
0.0GlnXaa: 0.0 ± 0.0
Arg
3.12ArgAla: 3.12 ± 0.219
1.17ArgCys: 1.17 ± 0.606
3.12ArgAsp: 3.12 ± 0.392
3.51ArgGlu: 3.51 ± 0.594
2.34ArgPhe: 2.34 ± 0.623
2.73ArgGly: 2.73 ± 0.421
1.17ArgHis: 1.17 ± 0.606
5.07ArgIle: 5.07 ± 0.79
3.12ArgLys: 3.12 ± 1.615
3.9ArgLeu: 3.9 ± 0.796
0.0ArgMet: 0.0 ± 0.0
2.34ArgAsn: 2.34 ± 1.211
0.78ArgPro: 0.78 ± 0.208
2.34ArgGln: 2.34 ± 0.012
3.9ArgArg: 3.9 ± 0.796
4.29ArgSer: 4.29 ± 1.448
2.73ArgThr: 2.73 ± 1.413
2.73ArgVal: 2.73 ± 0.802
1.95ArgTrp: 1.95 ± 0.214
3.9ArgTyr: 3.9 ± 0.427
0.0ArgXaa: 0.0 ± 0.0
Ser
8.19SerAla: 8.19 ± 3.098
0.0SerCys: 0.0 ± 0.0
1.95SerAsp: 1.95 ± 0.214
4.68SerGlu: 4.68 ± 0.635
1.56SerPhe: 1.56 ± 0.196
4.68SerGly: 4.68 ± 1.246
0.78SerHis: 0.78 ± 0.208
6.24SerIle: 6.24 ± 0.784
3.12SerLys: 3.12 ± 0.219
7.8SerLeu: 7.8 ± 0.98
1.17SerMet: 1.17 ± 0.006
3.51SerAsn: 3.51 ± 0.629
3.9SerPro: 3.9 ± 1.65
1.17SerGln: 1.17 ± 0.006
3.12SerArg: 3.12 ± 0.219
2.73SerSer: 2.73 ± 1.644
4.29SerThr: 4.29 ± 0.225
6.24SerVal: 6.24 ± 0.439
1.17SerTrp: 1.17 ± 0.006
2.34SerTyr: 2.34 ± 0.012
0.0SerXaa: 0.0 ± 0.0
Thr
3.12ThrAla: 3.12 ± 0.831
1.56ThrCys: 1.56 ± 0.415
3.12ThrAsp: 3.12 ± 1.442
2.34ThrGlu: 2.34 ± 0.012
3.51ThrPhe: 3.51 ± 2.464
4.29ThrGly: 4.29 ± 0.998
0.0ThrHis: 0.0 ± 0.0
3.51ThrIle: 3.51 ± 1.817
3.12ThrLys: 3.12 ± 0.392
5.85ThrLeu: 5.85 ± 1.252
2.34ThrMet: 2.34 ± 0.713
2.34ThrAsn: 2.34 ± 0.6
4.68ThrPro: 4.68 ± 2.469
0.78ThrGln: 0.78 ± 0.208
2.73ThrArg: 2.73 ± 0.19
5.46ThrSer: 5.46 ± 0.843
6.24ThrThr: 6.24 ± 0.173
7.41ThrVal: 7.41 ± 1.056
1.56ThrTrp: 1.56 ± 0.196
1.56ThrTyr: 1.56 ± 0.808
0.0ThrXaa: 0.0 ± 0.0
Val
2.73ValAla: 2.73 ± 0.421
1.56ValCys: 1.56 ± 0.196
4.68ValAsp: 4.68 ± 1.246
4.29ValGlu: 4.29 ± 0.225
3.51ValPhe: 3.51 ± 1.817
3.12ValGly: 3.12 ± 0.219
1.95ValHis: 1.95 ± 1.009
3.9ValIle: 3.9 ± 1.039
5.85ValLys: 5.85 ± 0.582
7.8ValLeu: 7.8 ± 0.854
1.56ValMet: 1.56 ± 0.196
4.68ValAsn: 4.68 ± 0.588
2.73ValPro: 2.73 ± 1.644
1.95ValGln: 1.95 ± 0.398
5.46ValArg: 5.46 ± 1.603
7.41ValSer: 7.41 ± 4.114
3.12ValThr: 3.12 ± 0.219
7.41ValVal: 7.41 ± 0.778
1.17ValTrp: 1.17 ± 0.617
3.51ValTyr: 3.51 ± 0.594
0.0ValXaa: 0.0 ± 0.0
Trp
1.56TrpAla: 1.56 ± 0.196
0.78TrpCys: 0.78 ± 0.404
1.17TrpAsp: 1.17 ± 0.606
1.56TrpGlu: 1.56 ± 0.196
0.0TrpPhe: 0.0 ± 0.0
0.78TrpGly: 0.78 ± 0.208
1.17TrpHis: 1.17 ± 0.606
1.56TrpIle: 1.56 ± 0.196
0.78TrpLys: 0.78 ± 0.404
0.78TrpLeu: 0.78 ± 0.404
0.39TrpMet: 0.39 ± 0.41
0.39TrpAsn: 0.39 ± 0.41
0.78TrpPro: 0.78 ± 0.819
0.0TrpGln: 0.0 ± 0.0
1.56TrpArg: 1.56 ± 1.027
1.17TrpSer: 1.17 ± 0.606
0.78TrpThr: 0.78 ± 0.208
0.39TrpVal: 0.39 ± 0.41
0.78TrpTrp: 0.78 ± 0.404
1.17TrpTyr: 1.17 ± 0.006
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.51TyrAla: 3.51 ± 0.018
0.78TyrCys: 0.78 ± 0.208
2.73TyrAsp: 2.73 ± 0.19
3.9TyrGlu: 3.9 ± 1.407
2.73TyrPhe: 2.73 ± 0.19
2.73TyrGly: 2.73 ± 0.19
0.78TyrHis: 0.78 ± 0.404
2.34TyrIle: 2.34 ± 0.012
1.95TyrLys: 1.95 ± 0.398
5.07TyrLeu: 5.07 ± 0.179
1.95TyrMet: 1.95 ± 0.398
1.56TyrAsn: 1.56 ± 0.196
1.56TyrPro: 1.56 ± 1.638
1.17TyrGln: 1.17 ± 0.606
1.17TyrArg: 1.17 ± 0.006
4.29TyrSer: 4.29 ± 0.225
3.12TyrThr: 3.12 ± 0.392
2.34TyrVal: 2.34 ± 1.235
1.17TyrTrp: 1.17 ± 0.006
1.17TyrTyr: 1.17 ± 0.006
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2565 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski