Amino acid dipepetide frequency for Schaalia cardiffensis F0333

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
13.549AlaAla: 13.549 ± 0.214
1.101AlaCys: 1.101 ± 0.042
6.263AlaAsp: 6.263 ± 0.1
7.414AlaGlu: 7.414 ± 0.111
3.614AlaPhe: 3.614 ± 0.091
9.23AlaGly: 9.23 ± 0.135
2.7AlaHis: 2.7 ± 0.071
5.422AlaIle: 5.422 ± 0.096
3.908AlaLys: 3.908 ± 0.1
13.865AlaLeu: 13.865 ± 0.172
2.693AlaMet: 2.693 ± 0.064
2.5AlaAsn: 2.5 ± 0.076
6.012AlaPro: 6.012 ± 0.136
4.629AlaGln: 4.629 ± 0.106
8.428AlaArg: 8.428 ± 0.125
8.086AlaSer: 8.086 ± 0.142
5.671AlaThr: 5.671 ± 0.1
7.836AlaVal: 7.836 ± 0.126
1.725AlaTrp: 1.725 ± 0.059
2.093AlaTyr: 2.093 ± 0.06
0.0AlaXaa: 0.0 ± 0.0
Cys
1.104CysAla: 1.104 ± 0.042
0.083CysCys: 0.083 ± 0.013
0.434CysAsp: 0.434 ± 0.028
0.678CysGlu: 0.678 ± 0.035
0.259CysPhe: 0.259 ± 0.023
0.858CysGly: 0.858 ± 0.045
0.199CysHis: 0.199 ± 0.017
0.267CysIle: 0.267 ± 0.02
0.115CysLys: 0.115 ± 0.013
0.707CysLeu: 0.707 ± 0.036
0.134CysMet: 0.134 ± 0.012
0.135CysAsn: 0.135 ± 0.017
0.49CysPro: 0.49 ± 0.031
0.239CysGln: 0.239 ± 0.02
0.493CysArg: 0.493 ± 0.027
0.603CysSer: 0.603 ± 0.034
0.501CysThr: 0.501 ± 0.028
0.659CysVal: 0.659 ± 0.029
0.089CysTrp: 0.089 ± 0.012
0.202CysTyr: 0.202 ± 0.019
0.0CysXaa: 0.0 ± 0.0
Asp
6.766AspAla: 6.766 ± 0.118
0.407AspCys: 0.407 ± 0.022
2.734AspAsp: 2.734 ± 0.071
4.779AspGlu: 4.779 ± 0.1
1.916AspPhe: 1.916 ± 0.05
4.289AspGly: 4.289 ± 0.114
1.2AspHis: 1.2 ± 0.053
2.533AspIle: 2.533 ± 0.079
1.396AspLys: 1.396 ± 0.058
6.103AspLeu: 6.103 ± 0.108
1.187AspMet: 1.187 ± 0.042
0.969AspAsn: 0.969 ± 0.042
3.997AspPro: 3.997 ± 0.084
1.617AspGln: 1.617 ± 0.048
3.348AspArg: 3.348 ± 0.086
3.91AspSer: 3.91 ± 0.077
2.713AspThr: 2.713 ± 0.058
4.209AspVal: 4.209 ± 0.088
0.734AspTrp: 0.734 ± 0.034
1.324AspTyr: 1.324 ± 0.059
0.0AspXaa: 0.0 ± 0.0
Glu
8.523GluAla: 8.523 ± 0.133
0.509GluCys: 0.509 ± 0.033
4.282GluAsp: 4.282 ± 0.091
5.571GluGlu: 5.571 ± 0.113
1.766GluPhe: 1.766 ± 0.056
5.96GluGly: 5.96 ± 0.116
1.618GluHis: 1.618 ± 0.057
3.318GluIle: 3.318 ± 0.081
2.28GluLys: 2.28 ± 0.075
6.933GluLeu: 6.933 ± 0.102
1.44GluMet: 1.44 ± 0.046
1.626GluAsn: 1.626 ± 0.05
2.758GluPro: 2.758 ± 0.066
2.357GluGln: 2.357 ± 0.066
5.07GluArg: 5.07 ± 0.111
3.609GluSer: 3.609 ± 0.082
3.046GluThr: 3.046 ± 0.075
5.229GluVal: 5.229 ± 0.078
0.944GluTrp: 0.944 ± 0.044
1.265GluTyr: 1.265 ± 0.049
0.0GluXaa: 0.0 ± 0.0
Phe
3.671PheAla: 3.671 ± 0.081
0.259PheCys: 0.259 ± 0.021
2.196PheAsp: 2.196 ± 0.063
2.061PheGlu: 2.061 ± 0.056
1.241PhePhe: 1.241 ± 0.057
2.864PheGly: 2.864 ± 0.076
0.702PheHis: 0.702 ± 0.037
1.493PheIle: 1.493 ± 0.054
0.738PheLys: 0.738 ± 0.041
3.047PheLeu: 3.047 ± 0.079
0.6PheMet: 0.6 ± 0.038
0.764PheAsn: 0.764 ± 0.035
1.442PhePro: 1.442 ± 0.047
0.71PheGln: 0.71 ± 0.034
1.515PheArg: 1.515 ± 0.054
2.229PheSer: 2.229 ± 0.062
2.28PheThr: 2.28 ± 0.057
2.309PheVal: 2.309 ± 0.064
0.401PheTrp: 0.401 ± 0.026
0.598PheTyr: 0.598 ± 0.035
0.0PheXaa: 0.0 ± 0.0
Gly
9.903GlyAla: 9.903 ± 0.131
0.711GlyCys: 0.711 ± 0.038
4.133GlyAsp: 4.133 ± 0.09
5.632GlyGlu: 5.632 ± 0.106
2.882GlyPhe: 2.882 ± 0.082
6.442GlyGly: 6.442 ± 0.137
1.779GlyHis: 1.779 ± 0.055
4.599GlyIle: 4.599 ± 0.085
2.751GlyLys: 2.751 ± 0.073
8.132GlyLeu: 8.132 ± 0.121
2.054GlyMet: 2.054 ± 0.066
1.682GlyAsn: 1.682 ± 0.057
3.471GlyPro: 3.471 ± 0.08
2.552GlyGln: 2.552 ± 0.088
5.918GlyArg: 5.918 ± 0.115
5.337GlySer: 5.337 ± 0.115
5.062GlyThr: 5.062 ± 0.112
7.067GlyVal: 7.067 ± 0.123
1.443GlyTrp: 1.443 ± 0.057
1.895GlyTyr: 1.895 ± 0.063
0.0GlyXaa: 0.0 ± 0.0
His
2.237HisAla: 2.237 ± 0.073
0.212HisCys: 0.212 ± 0.02
1.19HisAsp: 1.19 ± 0.048
1.513HisGlu: 1.513 ± 0.052
0.616HisPhe: 0.616 ± 0.033
1.744HisGly: 1.744 ± 0.057
0.562HisHis: 0.562 ± 0.031
0.878HisIle: 0.878 ± 0.033
0.473HisLys: 0.473 ± 0.03
2.142HisLeu: 2.142 ± 0.062
0.466HisMet: 0.466 ± 0.027
0.547HisAsn: 0.547 ± 0.029
1.556HisPro: 1.556 ± 0.051
0.551HisGln: 0.551 ± 0.032
1.641HisArg: 1.641 ± 0.062
1.552HisSer: 1.552 ± 0.053
1.222HisThr: 1.222 ± 0.045
1.588HisVal: 1.588 ± 0.052
0.32HisTrp: 0.32 ± 0.023
0.455HisTyr: 0.455 ± 0.029
0.0HisXaa: 0.0 ± 0.0
Ile
6.65IleAla: 6.65 ± 0.112
0.46IleCys: 0.46 ± 0.027
3.751IleAsp: 3.751 ± 0.083
3.59IleGlu: 3.59 ± 0.083
1.259IlePhe: 1.259 ± 0.057
4.798IleGly: 4.798 ± 0.095
1.057IleHis: 1.057 ± 0.04
2.541IleIle: 2.541 ± 0.074
0.979IleLys: 0.979 ± 0.041
4.946IleLeu: 4.946 ± 0.119
0.925IleMet: 0.925 ± 0.044
1.053IleAsn: 1.053 ± 0.047
2.944IlePro: 2.944 ± 0.067
1.152IleGln: 1.152 ± 0.042
3.164IleArg: 3.164 ± 0.065
2.915IleSer: 2.915 ± 0.07
3.076IleThr: 3.076 ± 0.073
4.303IleVal: 4.303 ± 0.092
0.508IleTrp: 0.508 ± 0.032
0.729IleTyr: 0.729 ± 0.033
0.0IleXaa: 0.0 ± 0.0
Lys
3.74LysAla: 3.74 ± 0.091
0.146LysCys: 0.146 ± 0.015
1.883LysAsp: 1.883 ± 0.061
2.171LysGlu: 2.171 ± 0.06
0.59LysPhe: 0.59 ± 0.034
2.778LysGly: 2.778 ± 0.067
0.493LysHis: 0.493 ± 0.03
1.486LysIle: 1.486 ± 0.054
1.448LysLys: 1.448 ± 0.057
2.179LysLeu: 2.179 ± 0.06
0.676LysMet: 0.676 ± 0.033
0.979LysAsn: 0.979 ± 0.039
1.396LysPro: 1.396 ± 0.049
0.81LysGln: 0.81 ± 0.033
2.412LysArg: 2.412 ± 0.069
1.833LysSer: 1.833 ± 0.055
2.058LysThr: 2.058 ± 0.074
2.279LysVal: 2.279 ± 0.086
0.454LysTrp: 0.454 ± 0.029
0.539LysTyr: 0.539 ± 0.029
0.0LysXaa: 0.0 ± 0.0
Leu
12.965LeuAla: 12.965 ± 0.162
0.759LeuCys: 0.759 ± 0.035
6.338LeuAsp: 6.338 ± 0.133
6.731LeuGlu: 6.731 ± 0.114
2.974LeuPhe: 2.974 ± 0.073
8.652LeuGly: 8.652 ± 0.118
2.112LeuHis: 2.112 ± 0.058
5.153LeuIle: 5.153 ± 0.108
2.993LeuLys: 2.993 ± 0.072
10.221LeuLeu: 10.221 ± 0.163
2.016LeuMet: 2.016 ± 0.068
2.229LeuAsn: 2.229 ± 0.057
5.302LeuPro: 5.302 ± 0.098
2.109LeuGln: 2.109 ± 0.06
6.865LeuArg: 6.865 ± 0.136
7.113LeuSer: 7.113 ± 0.108
5.484LeuThr: 5.484 ± 0.094
8.91LeuVal: 8.91 ± 0.145
1.106LeuTrp: 1.106 ± 0.044
1.547LeuTyr: 1.547 ± 0.05
0.0LeuXaa: 0.0 ± 0.0
Met
2.225MetAla: 2.225 ± 0.064
0.165MetCys: 0.165 ± 0.017
1.122MetAsp: 1.122 ± 0.039
1.122MetGlu: 1.122 ± 0.045
0.6MetPhe: 0.6 ± 0.036
1.822MetGly: 1.822 ± 0.059
0.419MetHis: 0.419 ± 0.024
1.106MetIle: 1.106 ± 0.044
0.813MetLys: 0.813 ± 0.035
2.136MetLeu: 2.136 ± 0.062
0.514MetMet: 0.514 ± 0.028
0.778MetAsn: 0.778 ± 0.04
1.329MetPro: 1.329 ± 0.046
0.489MetGln: 0.489 ± 0.025
1.835MetArg: 1.835 ± 0.053
1.884MetSer: 1.884 ± 0.055
1.784MetThr: 1.784 ± 0.048
1.56MetVal: 1.56 ± 0.049
0.283MetTrp: 0.283 ± 0.021
0.334MetTyr: 0.334 ± 0.025
0.0MetXaa: 0.0 ± 0.0
Asn
2.852AsnAla: 2.852 ± 0.07
0.177AsnCys: 0.177 ± 0.018
1.211AsnAsp: 1.211 ± 0.053
1.524AsnGlu: 1.524 ± 0.059
0.629AsnPhe: 0.629 ± 0.036
2.037AsnGly: 2.037 ± 0.067
0.444AsnHis: 0.444 ± 0.025
1.061AsnIle: 1.061 ± 0.043
0.547AsnLys: 0.547 ± 0.034
2.241AsnLeu: 2.241 ± 0.07
0.471AsnMet: 0.471 ± 0.028
0.509AsnAsn: 0.509 ± 0.031
1.672AsnPro: 1.672 ± 0.06
0.672AsnGln: 0.672 ± 0.036
1.458AsnArg: 1.458 ± 0.051
1.439AsnSer: 1.439 ± 0.056
1.447AsnThr: 1.447 ± 0.046
1.622AsnVal: 1.622 ± 0.056
0.345AsnTrp: 0.345 ± 0.021
0.552AsnTyr: 0.552 ± 0.029
0.0AsnXaa: 0.0 ± 0.0
Pro
5.77ProAla: 5.77 ± 0.122
0.368ProCys: 0.368 ± 0.025
2.877ProAsp: 2.877 ± 0.065
4.349ProGlu: 4.349 ± 0.078
1.591ProPhe: 1.591 ± 0.057
4.551ProGly: 4.551 ± 0.098
1.128ProHis: 1.128 ± 0.049
2.503ProIle: 2.503 ± 0.06
1.77ProLys: 1.77 ± 0.054
5.267ProLeu: 5.267 ± 0.104
1.057ProMet: 1.057 ± 0.04
1.271ProAsn: 1.271 ± 0.053
1.945ProPro: 1.945 ± 0.069
1.913ProGln: 1.913 ± 0.074
3.149ProArg: 3.149 ± 0.086
4.077ProSer: 4.077 ± 0.099
3.03ProThr: 3.03 ± 0.078
3.975ProVal: 3.975 ± 0.086
0.81ProTrp: 0.81 ± 0.043
1.03ProTyr: 1.03 ± 0.04
0.0ProXaa: 0.0 ± 0.0
Gln
3.937GlnAla: 3.937 ± 0.1
0.213GlnCys: 0.213 ± 0.019
1.424GlnAsp: 1.424 ± 0.049
1.736GlnGlu: 1.736 ± 0.056
0.753GlnPhe: 0.753 ± 0.032
2.541GlnGly: 2.541 ± 0.083
0.606GlnHis: 0.606 ± 0.031
1.957GlnIle: 1.957 ± 0.061
0.87GlnLys: 0.87 ± 0.035
2.675GlnLeu: 2.675 ± 0.061
0.896GlnMet: 0.896 ± 0.039
0.662GlnAsn: 0.662 ± 0.033
1.286GlnPro: 1.286 ± 0.061
0.968GlnGln: 0.968 ± 0.067
2.347GlnArg: 2.347 ± 0.074
1.868GlnSer: 1.868 ± 0.062
1.582GlnThr: 1.582 ± 0.053
2.517GlnVal: 2.517 ± 0.056
0.535GlnTrp: 0.535 ± 0.034
0.544GlnTyr: 0.544 ± 0.026
0.0GlnXaa: 0.0 ± 0.0
Arg
7.868ArgAla: 7.868 ± 0.113
0.571ArgCys: 0.571 ± 0.036
3.308ArgAsp: 3.308 ± 0.087
4.685ArgGlu: 4.685 ± 0.108
2.384ArgPhe: 2.384 ± 0.068
5.097ArgGly: 5.097 ± 0.113
1.48ArgHis: 1.48 ± 0.053
4.289ArgIle: 4.289 ± 0.083
2.07ArgLys: 2.07 ± 0.063
6.894ArgLeu: 6.894 ± 0.123
1.813ArgMet: 1.813 ± 0.053
1.459ArgAsn: 1.459 ± 0.042
3.437ArgPro: 3.437 ± 0.087
2.115ArgGln: 2.115 ± 0.064
5.687ArgArg: 5.687 ± 0.127
4.54ArgSer: 4.54 ± 0.097
3.806ArgThr: 3.806 ± 0.082
5.28ArgVal: 5.28 ± 0.104
0.975ArgTrp: 0.975 ± 0.039
1.34ArgTyr: 1.34 ± 0.048
0.0ArgXaa: 0.0 ± 0.0
Ser
7.764SerAla: 7.764 ± 0.117
0.579SerCys: 0.579 ± 0.033
3.49SerAsp: 3.49 ± 0.079
3.956SerGlu: 3.956 ± 0.085
2.404SerPhe: 2.404 ± 0.069
6.431SerGly: 6.431 ± 0.121
1.356SerHis: 1.356 ± 0.052
3.307SerIle: 3.307 ± 0.078
1.988SerLys: 1.988 ± 0.06
6.505SerLeu: 6.505 ± 0.106
1.623SerMet: 1.623 ± 0.05
1.416SerAsn: 1.416 ± 0.055
3.585SerPro: 3.585 ± 0.093
2.241SerGln: 2.241 ± 0.064
4.249SerArg: 4.249 ± 0.093
5.228SerSer: 5.228 ± 0.156
4.161SerThr: 4.161 ± 0.098
4.842SerVal: 4.842 ± 0.093
1.109SerTrp: 1.109 ± 0.046
1.448SerTyr: 1.448 ± 0.051
0.0SerXaa: 0.0 ± 0.0
Thr
5.667ThrAla: 5.667 ± 0.106
0.516ThrCys: 0.516 ± 0.032
2.67ThrAsp: 2.67 ± 0.069
2.809ThrGlu: 2.809 ± 0.071
1.669ThrPhe: 1.669 ± 0.057
4.981ThrGly: 4.981 ± 0.08
1.33ThrHis: 1.33 ± 0.052
3.242ThrIle: 3.242 ± 0.072
1.633ThrLys: 1.633 ± 0.057
5.96ThrLeu: 5.96 ± 0.106
1.322ThrMet: 1.322 ± 0.047
1.466ThrAsn: 1.466 ± 0.061
4.145ThrPro: 4.145 ± 0.078
1.836ThrGln: 1.836 ± 0.055
4.067ThrArg: 4.067 ± 0.084
3.824ThrSer: 3.824 ± 0.084
3.439ThrThr: 3.439 ± 0.083
4.22ThrVal: 4.22 ± 0.102
0.904ThrTrp: 0.904 ± 0.053
1.173ThrTyr: 1.173 ± 0.051
0.0ThrXaa: 0.0 ± 0.0
Val
7.942ValAla: 7.942 ± 0.129
0.687ValCys: 0.687 ± 0.033
4.984ValAsp: 4.984 ± 0.091
5.6ValGlu: 5.6 ± 0.097
2.755ValPhe: 2.755 ± 0.074
5.625ValGly: 5.625 ± 0.111
1.68ValHis: 1.68 ± 0.053
4.088ValIle: 4.088 ± 0.096
2.634ValLys: 2.634 ± 0.073
8.229ValLeu: 8.229 ± 0.144
1.636ValMet: 1.636 ± 0.051
1.97ValAsn: 1.97 ± 0.059
4.066ValPro: 4.066 ± 0.093
1.948ValGln: 1.948 ± 0.061
5.022ValArg: 5.022 ± 0.104
5.377ValSer: 5.377 ± 0.093
4.453ValThr: 4.453 ± 0.087
6.349ValVal: 6.349 ± 0.141
0.917ValTrp: 0.917 ± 0.036
1.343ValTyr: 1.343 ± 0.049
0.0ValXaa: 0.0 ± 0.0
Trp
1.528TrpAla: 1.528 ± 0.059
0.134TrpCys: 0.134 ± 0.016
0.791TrpAsp: 0.791 ± 0.033
0.82TrpGlu: 0.82 ± 0.04
0.485TrpPhe: 0.485 ± 0.029
1.082TrpGly: 1.082 ± 0.046
0.243TrpHis: 0.243 ± 0.019
0.756TrpIle: 0.756 ± 0.038
0.508TrpLys: 0.508 ± 0.026
1.415TrpLeu: 1.415 ± 0.052
0.412TrpMet: 0.412 ± 0.025
0.481TrpAsn: 0.481 ± 0.031
0.543TrpPro: 0.543 ± 0.031
0.45TrpGln: 0.45 ± 0.029
1.01TrpArg: 1.01 ± 0.043
0.893TrpSer: 0.893 ± 0.043
0.902TrpThr: 0.902 ± 0.039
1.095TrpVal: 1.095 ± 0.045
0.333TrpTrp: 0.333 ± 0.022
0.352TrpTyr: 0.352 ± 0.035
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.078TyrAla: 2.078 ± 0.059
0.193TyrCys: 0.193 ± 0.016
1.049TyrAsp: 1.049 ± 0.04
1.365TyrGlu: 1.365 ± 0.047
0.734TyrPhe: 0.734 ± 0.041
1.665TyrGly: 1.665 ± 0.053
0.356TyrHis: 0.356 ± 0.021
0.799TyrIle: 0.799 ± 0.038
0.436TyrLys: 0.436 ± 0.025
1.984TyrLeu: 1.984 ± 0.075
0.382TyrMet: 0.382 ± 0.026
0.411TyrAsn: 0.411 ± 0.031
1.055TyrPro: 1.055 ± 0.056
0.563TyrGln: 0.563 ± 0.029
1.419TyrArg: 1.419 ± 0.05
1.365TyrSer: 1.365 ± 0.049
1.155TyrThr: 1.155 ± 0.057
1.456TyrVal: 1.456 ± 0.051
0.298TyrTrp: 0.298 ± 0.024
0.485TyrTyr: 0.485 ± 0.041
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1983 proteins (628407 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski