Human papillomavirus type 137

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Gammapapillomavirus; Gammapapillomavirus 16

Average proteome isoelectric point is 6.07

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|I3P6M3|I3P6M3_9PAPI Major capsid protein L1 OS=Human papillomavirus type 137 OX=1070410 GN=L1 PE=3 SV=1
MM1 pKa = 7.07QANKK5 pKa = 9.57RR6 pKa = 11.84RR7 pKa = 11.84KK8 pKa = 8.32RR9 pKa = 11.84AAVEE13 pKa = 4.12DD14 pKa = 4.67IYY16 pKa = 11.66AKK18 pKa = 10.82GCTQPGGYY26 pKa = 9.78CPPDD30 pKa = 3.29VKK32 pKa = 11.21NKK34 pKa = 10.1VEE36 pKa = 4.16GNTWADD42 pKa = 3.41FLLKK46 pKa = 10.8VFGSVVYY53 pKa = 10.04FGGLGIGTGKK63 pKa = 8.78GTGGSTGYY71 pKa = 8.7TPLGGTVGSRR81 pKa = 11.84GTTNTIKK88 pKa = 9.55PTIPLDD94 pKa = 3.65PLGVPDD100 pKa = 5.02IVTVDD105 pKa = 4.64PIAPEE110 pKa = 3.85AASIVPLAEE119 pKa = 4.24GLPEE123 pKa = 4.8PGVIDD128 pKa = 3.71TGTSFPGLAADD139 pKa = 4.09NEE141 pKa = 4.68NIVTVLDD148 pKa = 3.99PLSEE152 pKa = 4.1VTGVGEE158 pKa = 4.44HH159 pKa = 6.8PNIITGGTADD169 pKa = 4.07SPAILDD175 pKa = 4.04VQTSPPPAKK184 pKa = 10.25KK185 pKa = 9.96ILLDD189 pKa = 3.62PSISKK194 pKa = 7.22TTTAVQTHH202 pKa = 6.94ASHH205 pKa = 7.25VDD207 pKa = 2.93ANLNIFVDD215 pKa = 3.91AQSFGTHH222 pKa = 4.75VGYY225 pKa = 9.07TEE227 pKa = 5.89DD228 pKa = 4.59IPLEE232 pKa = 4.37EE233 pKa = 4.25INLRR237 pKa = 11.84SEE239 pKa = 4.62FEE241 pKa = 4.61LEE243 pKa = 3.89DD244 pKa = 4.11SEE246 pKa = 5.25PKK248 pKa = 10.22TSTPFAEE255 pKa = 4.02RR256 pKa = 11.84VLNKK260 pKa = 9.38TKK262 pKa = 10.41QLYY265 pKa = 9.64SKK267 pKa = 10.34YY268 pKa = 8.56VQQVPTRR275 pKa = 11.84PAEE278 pKa = 3.91FALYY282 pKa = 9.08TSRR285 pKa = 11.84FEE287 pKa = 4.4FEE289 pKa = 4.0NPAFEE294 pKa = 4.82EE295 pKa = 4.3DD296 pKa = 3.26VTMEE300 pKa = 4.34FEE302 pKa = 4.21NDD304 pKa = 3.1LAEE307 pKa = 4.96IGEE310 pKa = 4.36ITTPAVSDD318 pKa = 3.51VRR320 pKa = 11.84ILNRR324 pKa = 11.84PIYY327 pKa = 10.62SEE329 pKa = 3.91TADD332 pKa = 3.45RR333 pKa = 11.84TVRR336 pKa = 11.84ISRR339 pKa = 11.84LGQRR343 pKa = 11.84AGMKK347 pKa = 8.71TRR349 pKa = 11.84SGLEE353 pKa = 3.11IGQRR357 pKa = 11.84VHH359 pKa = 7.42FYY361 pKa = 10.99FDD363 pKa = 3.54LSDD366 pKa = 3.56IPRR369 pKa = 11.84EE370 pKa = 4.16SIEE373 pKa = 3.95LNTYY377 pKa = 10.18GNYY380 pKa = 9.35SHH382 pKa = 7.41EE383 pKa = 4.27STIVDD388 pKa = 3.76EE389 pKa = 4.81LLSSTFINPFEE400 pKa = 4.29MPVDD404 pKa = 3.79SEE406 pKa = 4.06IFAEE410 pKa = 4.95NEE412 pKa = 3.7LLDD415 pKa = 4.24PLEE418 pKa = 4.01EE419 pKa = 4.5DD420 pKa = 4.14FRR422 pKa = 11.84DD423 pKa = 3.54SHH425 pKa = 7.84IVVPYY430 pKa = 11.03LEE432 pKa = 5.47DD433 pKa = 3.41EE434 pKa = 4.67QINITPTLPPGLGLKK449 pKa = 10.04VYY451 pKa = 10.74SDD453 pKa = 3.54LSEE456 pKa = 4.77RR457 pKa = 11.84DD458 pKa = 3.62LLIHH462 pKa = 6.37YY463 pKa = 7.43PVQHH467 pKa = 7.02ADD469 pKa = 2.71IMVPDD474 pKa = 4.26TPYY477 pKa = 10.71IPVQPPDD484 pKa = 3.5GVLVDD489 pKa = 4.6DD490 pKa = 4.41NDD492 pKa = 4.27YY493 pKa = 10.95YY494 pKa = 11.45LHH496 pKa = 7.24PGLYY500 pKa = 8.83SRR502 pKa = 11.84KK503 pKa = 8.98RR504 pKa = 11.84KK505 pKa = 9.64RR506 pKa = 11.84RR507 pKa = 11.84VLL509 pKa = 3.52

Molecular weight: 55.82 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|I3P6M1|I3P6M1_9PAPI Uncharacterized protein OS=Human papillomavirus type 137 OX=1070410 GN=E4 PE=4 SV=1
MM1 pKa = 7.14NQTDD5 pKa = 3.99LKK7 pKa = 10.99NRR9 pKa = 11.84LDD11 pKa = 4.04ALQDD15 pKa = 3.59ALMTLYY21 pKa = 10.76EE22 pKa = 4.91KK23 pKa = 11.1DD24 pKa = 3.76PVDD27 pKa = 4.08LSSQIEE33 pKa = 4.61HH34 pKa = 6.43YY35 pKa = 10.88SLLRR39 pKa = 11.84KK40 pKa = 9.21EE41 pKa = 5.61AVLQYY46 pKa = 8.89YY47 pKa = 9.14CRR49 pKa = 11.84KK50 pKa = 9.37EE51 pKa = 4.24GYY53 pKa = 9.2RR54 pKa = 11.84QLGLQILPSLTVSEE68 pKa = 5.01HH69 pKa = 5.28NAKK72 pKa = 10.09EE73 pKa = 4.08AIKK76 pKa = 9.89MVIILKK82 pKa = 10.28SLSKK86 pKa = 10.75SQFAGEE92 pKa = 3.92RR93 pKa = 11.84WTLRR97 pKa = 11.84DD98 pKa = 3.24TSLEE102 pKa = 4.1LFNTAPKK109 pKa = 10.81NCFKK113 pKa = 10.92KK114 pKa = 10.44DD115 pKa = 3.37GYY117 pKa = 10.78EE118 pKa = 3.83VLVWFDD124 pKa = 3.78HH125 pKa = 7.13DD126 pKa = 4.51PNNAYY131 pKa = 9.61PYY133 pKa = 9.04TNWNNIYY140 pKa = 10.07YY141 pKa = 10.46QGDD144 pKa = 3.25NDD146 pKa = 3.51VWYY149 pKa = 8.4KK150 pKa = 9.53TAGKK154 pKa = 10.32VDD156 pKa = 4.44LNGLYY161 pKa = 10.49YY162 pKa = 10.5EE163 pKa = 5.75DD164 pKa = 3.98YY165 pKa = 11.3DD166 pKa = 3.77NVKK169 pKa = 10.35VYY171 pKa = 9.89FVLFQEE177 pKa = 5.08KK178 pKa = 10.5ADD180 pKa = 4.37LYY182 pKa = 10.42SKK184 pKa = 10.53SGEE187 pKa = 3.73WTVNFKK193 pKa = 10.96NEE195 pKa = 4.03QLSSSIASSTRR206 pKa = 11.84RR207 pKa = 11.84PIPLLSHH214 pKa = 5.21EE215 pKa = 4.52TNRR218 pKa = 11.84NGNGASRR225 pKa = 11.84ATTRR229 pKa = 11.84NASPTSTALPISSYY243 pKa = 10.76GGRR246 pKa = 11.84EE247 pKa = 3.68EE248 pKa = 4.62SEE250 pKa = 4.42SEE252 pKa = 4.14EE253 pKa = 4.72GPSSTSRR260 pKa = 11.84SPTGRR265 pKa = 11.84RR266 pKa = 11.84RR267 pKa = 11.84RR268 pKa = 11.84RR269 pKa = 11.84RR270 pKa = 11.84GGEE273 pKa = 3.71QGEE276 pKa = 4.66SAARR280 pKa = 11.84PQKK283 pKa = 10.34RR284 pKa = 11.84KK285 pKa = 10.0RR286 pKa = 11.84GGDD289 pKa = 3.59AVPTAAEE296 pKa = 4.02VGSNHH301 pKa = 5.46RR302 pKa = 11.84TVPSTGLSRR311 pKa = 11.84LTRR314 pKa = 11.84LQAEE318 pKa = 4.16ARR320 pKa = 11.84DD321 pKa = 3.83PQLILINGAANQLKK335 pKa = 9.47CFRR338 pKa = 11.84YY339 pKa = 9.46RR340 pKa = 11.84CYY342 pKa = 11.2AKK344 pKa = 10.57AKK346 pKa = 9.83QNFIAMSTVWHH357 pKa = 6.09WVNNEE362 pKa = 3.84HH363 pKa = 7.1KK364 pKa = 9.89EE365 pKa = 4.22SSSKK369 pKa = 10.96LLVAFDD375 pKa = 3.95SDD377 pKa = 3.49KK378 pKa = 11.14QRR380 pKa = 11.84DD381 pKa = 3.91LFLVTTTLPKK391 pKa = 10.56GCTYY395 pKa = 10.9CFGQLDD401 pKa = 4.23CFF403 pKa = 4.57

Molecular weight: 45.79 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2411

99

610

344.4

38.97

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.558 ± 0.345

2.323 ± 0.857

6.678 ± 0.444

6.512 ± 0.756

4.562 ± 0.519

5.226 ± 0.867

2.074 ± 0.144

4.936 ± 0.541

5.516 ± 0.753

10.079 ± 0.564

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.535 ± 0.35

5.309 ± 0.441

5.973 ± 1.168

4.023 ± 0.347

5.392 ± 0.684

7.507 ± 0.546

6.387 ± 0.458

5.682 ± 0.573

1.12 ± 0.317

3.608 ± 0.467
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski