Trichophyton rubrum (Athlete s foot fungus) (Epidermophyton rubrum)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Fungi; Dikarya; Ascomycota; saccharomyceta; Pezizomycotina; leotiomyceta; Eurotiomycetes; Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton

Average proteome isoelectric point is 6.63

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7033 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A178F474|A0A178F474_TRIRU Branched-chain-amino-acid aminotransferase OS=Trichophyton rubrum OX=5551 GN=A7C99_2345 PE=3 SV=1
MM1 pKa = 7.91RR2 pKa = 11.84FPLPILLASALAAASQVDD20 pKa = 3.87DD21 pKa = 5.77RR22 pKa = 11.84LPPWCSLATNVGGATCEE39 pKa = 3.88AFAHH43 pKa = 5.72YY44 pKa = 10.66NHH46 pKa = 7.22LSLDD50 pKa = 3.67LFEE53 pKa = 5.17EE54 pKa = 4.39LNPDD58 pKa = 3.64VEE60 pKa = 4.8CPDD63 pKa = 3.6LEE65 pKa = 4.21EE66 pKa = 4.58GRR68 pKa = 11.84FYY70 pKa = 11.06CIDD73 pKa = 3.82DD74 pKa = 4.15LYY76 pKa = 11.07EE77 pKa = 4.5PEE79 pKa = 5.16PEE81 pKa = 4.92PDD83 pKa = 4.31NDD85 pKa = 5.85DD86 pKa = 5.31DD87 pKa = 7.12DD88 pKa = 7.1DD89 pKa = 7.12DD90 pKa = 5.08EE91 pKa = 7.38DD92 pKa = 4.29SLSTSMTDD100 pKa = 3.73FATATKK106 pKa = 9.75PPTPAEE112 pKa = 3.88FTTIITGHH120 pKa = 5.72PTANISISTPTANLTSRR137 pKa = 11.84PATTARR143 pKa = 11.84GPTAVTTMTPPAAASSTQTTPNSAPNPEE171 pKa = 4.59ALVQAAAMYY180 pKa = 10.02GWLTMSAFTSYY191 pKa = 10.53HH192 pKa = 5.45LCRR195 pKa = 11.84RR196 pKa = 11.84IMLL199 pKa = 4.22

Molecular weight: 21.39 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A178F3S1|A0A178F3S1_TRIRU SNF2 family helicase/ATPase OS=Trichophyton rubrum OX=5551 GN=A7C99_1698 PE=4 SV=1
MM1 pKa = 8.21DD2 pKa = 5.9AGRR5 pKa = 11.84QAGGQAGQQDD15 pKa = 3.66AANARR20 pKa = 11.84KK21 pKa = 6.73TQRR24 pKa = 11.84YY25 pKa = 8.38CRR27 pKa = 11.84WLDD30 pKa = 3.6AGPKK34 pKa = 9.47GDD36 pKa = 3.66SSSWPPSPPNARR48 pKa = 11.84QQPRR52 pKa = 11.84DD53 pKa = 3.34RR54 pKa = 11.84GSEE57 pKa = 3.87MGHH60 pKa = 6.36LRR62 pKa = 11.84LSPVACLLQLRR73 pKa = 11.84RR74 pKa = 11.84FCLCALTILWRR85 pKa = 11.84AWKK88 pKa = 10.12RR89 pKa = 11.84GVPVPIDD96 pKa = 3.55FEE98 pKa = 4.72PEE100 pKa = 3.39TTAQQRR106 pKa = 11.84SPSSYY111 pKa = 9.93AGSSKK116 pKa = 10.74VSDD119 pKa = 3.87CQAASLARR127 pKa = 11.84SGGRR131 pKa = 11.84EE132 pKa = 3.64HH133 pKa = 7.1PTRR136 pKa = 11.84RR137 pKa = 11.84DD138 pKa = 3.63CLPSRR143 pKa = 11.84LLFALRR149 pKa = 11.84GAYY152 pKa = 9.46RR153 pKa = 11.84GHH155 pKa = 6.75RR156 pKa = 11.84CC157 pKa = 4.02

Molecular weight: 17.32 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7033

0

7033

3906683

66

7871

555.5

61.52

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

8.222 ± 0.024

1.186 ± 0.01

5.635 ± 0.02

6.315 ± 0.028

3.579 ± 0.017

6.621 ± 0.024

2.414 ± 0.012

5.099 ± 0.021

5.143 ± 0.026

8.79 ± 0.029

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.101 ± 0.008

3.831 ± 0.014

6.245 ± 0.033

4.156 ± 0.021

6.17 ± 0.026

8.77 ± 0.028

5.93 ± 0.017

5.804 ± 0.021

1.278 ± 0.009

2.708 ± 0.012
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski