Amino acid dipepetide frequency for Lysobacter concretionis Ko07 = DSM 16239

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.218AlaAla: 17.218 ± 0.231	1.085AlaCys: 1.085 ± 0.044	7.822AlaAsp: 7.822 ± 0.114	7.192AlaGlu: 7.192 ± 0.1	4.104AlaPhe: 4.104 ± 0.075	11.672AlaGly: 11.672 ± 0.138	2.501AlaHis: 2.501 ± 0.069	5.951AlaIle: 5.951 ± 0.105	3.336AlaLys: 3.336 ± 0.089	14.725AlaLeu: 14.725 ± 0.184	3.597AlaMet: 3.597 ± 0.07	2.948AlaAsn: 2.948 ± 0.068	5.903AlaPro: 5.903 ± 0.108	4.897AlaGln: 4.897 ± 0.08	9.56AlaArg: 9.56 ± 0.14	6.229AlaSer: 6.229 ± 0.093	6.498AlaThr: 6.498 ± 0.095	8.719AlaVal: 8.719 ± 0.119	1.761AlaTrp: 1.761 ± 0.058	2.319AlaTyr: 2.319 ± 0.058	0.0AlaXaa: 0.0 ± 0.0
Cys	0.993CysAla: 0.993 ± 0.039	0.088CysCys: 0.088 ± 0.011	0.501CysAsp: 0.501 ± 0.026	0.468CysGlu: 0.468 ± 0.025	0.235CysPhe: 0.235 ± 0.019	0.834CysGly: 0.834 ± 0.035	0.226CysHis: 0.226 ± 0.018	0.366CysIle: 0.366 ± 0.024	0.188CysLys: 0.188 ± 0.018	0.7CysLeu: 0.7 ± 0.032	0.111CysMet: 0.111 ± 0.013	0.215CysAsn: 0.215 ± 0.017	0.396CysPro: 0.396 ± 0.025	0.218CysGln: 0.218 ± 0.017	0.561CysArg: 0.561 ± 0.03	0.447CysSer: 0.447 ± 0.029	0.416CysThr: 0.416 ± 0.025	0.632CysVal: 0.632 ± 0.032	0.105CysTrp: 0.105 ± 0.011	0.185CysTyr: 0.185 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	8.579AspAla: 8.579 ± 0.141	0.436AspCys: 0.436 ± 0.025	3.717AspAsp: 3.717 ± 0.076	3.643AspGlu: 3.643 ± 0.063	2.14AspPhe: 2.14 ± 0.054	6.209AspGly: 6.209 ± 0.108	1.307AspHis: 1.307 ± 0.045	2.59AspIle: 2.59 ± 0.066	1.701AspLys: 1.701 ± 0.055	5.679AspLeu: 5.679 ± 0.089	1.167AspMet: 1.167 ± 0.041	1.435AspAsn: 1.435 ± 0.051	3.671AspPro: 3.671 ± 0.078	1.824AspGln: 1.824 ± 0.046	4.405AspArg: 4.405 ± 0.082	2.732AspSer: 2.732 ± 0.072	2.97AspThr: 2.97 ± 0.057	4.343AspVal: 4.343 ± 0.087	1.105AspTrp: 1.105 ± 0.042	1.712AspTyr: 1.712 ± 0.055	0.0AspXaa: 0.0 ± 0.0
Glu	7.098GluAla: 7.098 ± 0.118	0.357GluCys: 0.357 ± 0.021	2.558GluAsp: 2.558 ± 0.067	2.381GluGlu: 2.381 ± 0.062	1.865GluPhe: 1.865 ± 0.059	3.945GluGly: 3.945 ± 0.071	1.515GluHis: 1.515 ± 0.051	2.636GluIle: 2.636 ± 0.068	1.543GluLys: 1.543 ± 0.053	6.561GluLeu: 6.561 ± 0.104	1.273GluMet: 1.273 ± 0.043	1.262GluAsn: 1.262 ± 0.045	2.779GluPro: 2.779 ± 0.065	2.581GluGln: 2.581 ± 0.068	5.122GluArg: 5.122 ± 0.099	2.686GluSer: 2.686 ± 0.059	2.66GluThr: 2.66 ± 0.066	4.194GluVal: 4.194 ± 0.07	0.693GluTrp: 0.693 ± 0.028	1.194GluTyr: 1.194 ± 0.04	0.0GluXaa: 0.0 ± 0.0
Phe	4.259PheAla: 4.259 ± 0.074	0.35PheCys: 0.35 ± 0.022	2.89PheAsp: 2.89 ± 0.06	2.047PheGlu: 2.047 ± 0.057	1.209PhePhe: 1.209 ± 0.047	3.429PheGly: 3.429 ± 0.076	0.822PheHis: 0.822 ± 0.034	1.377PheIle: 1.377 ± 0.042	0.89PheLys: 0.89 ± 0.037	2.883PheLeu: 2.883 ± 0.072	0.659PheMet: 0.659 ± 0.033	1.03PheAsn: 1.03 ± 0.037	1.415PhePro: 1.415 ± 0.048	0.957PheGln: 0.957 ± 0.042	2.165PheArg: 2.165 ± 0.054	1.915PheSer: 1.915 ± 0.059	1.685PheThr: 1.685 ± 0.048	2.523PheVal: 2.523 ± 0.061	0.503PheTrp: 0.503 ± 0.03	0.784PheTyr: 0.784 ± 0.035	0.0PheXaa: 0.0 ± 0.0
Gly	8.903GlyAla: 8.903 ± 0.133	0.761GlyCys: 0.761 ± 0.032	5.172GlyAsp: 5.172 ± 0.093	5.087GlyGlu: 5.087 ± 0.079	3.524GlyPhe: 3.524 ± 0.077	7.244GlyGly: 7.244 ± 0.129	2.211GlyHis: 2.211 ± 0.053	4.268GlyIle: 4.268 ± 0.08	3.191GlyLys: 3.191 ± 0.076	9.107GlyLeu: 9.107 ± 0.11	2.401GlyMet: 2.401 ± 0.061	2.433GlyAsn: 2.433 ± 0.066	3.251GlyPro: 3.251 ± 0.067	3.189GlyGln: 3.189 ± 0.068	6.19GlyArg: 6.19 ± 0.102	5.006GlySer: 5.006 ± 0.086	4.294GlyThr: 4.294 ± 0.082	6.61GlyVal: 6.61 ± 0.095	1.59GlyTrp: 1.59 ± 0.046	2.338GlyTyr: 2.338 ± 0.058	0.0GlyXaa: 0.0 ± 0.0
His	3.037HisAla: 3.037 ± 0.075	0.289HisCys: 0.289 ± 0.019	1.478HisAsp: 1.478 ± 0.052	1.236HisGlu: 1.236 ± 0.038	0.827HisPhe: 0.827 ± 0.036	2.344HisGly: 2.344 ± 0.065	0.653HisHis: 0.653 ± 0.034	0.832HisIle: 0.832 ± 0.03	0.507HisLys: 0.507 ± 0.03	2.173HisLeu: 2.173 ± 0.054	0.411HisMet: 0.411 ± 0.025	0.485HisAsn: 0.485 ± 0.025	1.562HisPro: 1.562 ± 0.051	0.663HisGln: 0.663 ± 0.029	1.697HisArg: 1.697 ± 0.05	1.008HisSer: 1.008 ± 0.037	1.017HisThr: 1.017 ± 0.042	1.612HisVal: 1.612 ± 0.051	0.408HisTrp: 0.408 ± 0.021	0.658HisTyr: 0.658 ± 0.03	0.0HisXaa: 0.0 ± 0.0
Ile	6.64IleAla: 6.64 ± 0.105	0.362IleCys: 0.362 ± 0.021	3.674IleAsp: 3.674 ± 0.071	3.305IleGlu: 3.305 ± 0.069	1.116IlePhe: 1.116 ± 0.049	4.59IleGly: 4.59 ± 0.09	0.913IleHis: 0.913 ± 0.034	1.427IleIle: 1.427 ± 0.054	1.273IleLys: 1.273 ± 0.045	3.135IleLeu: 3.135 ± 0.066	0.547IleMet: 0.547 ± 0.028	1.315IleAsn: 1.315 ± 0.039	2.159IlePro: 2.159 ± 0.06	1.254IleGln: 1.254 ± 0.041	2.921IleArg: 2.921 ± 0.059	2.312IleSer: 2.312 ± 0.064	2.246IleThr: 2.246 ± 0.062	3.383IleVal: 3.383 ± 0.075	0.45IleTrp: 0.45 ± 0.025	0.835IleTyr: 0.835 ± 0.039	0.0IleXaa: 0.0 ± 0.0
Lys	3.433LysAla: 3.433 ± 0.094	0.134LysCys: 0.134 ± 0.015	1.481LysAsp: 1.481 ± 0.057	1.203LysGlu: 1.203 ± 0.047	0.751LysPhe: 0.751 ± 0.036	2.002LysGly: 2.002 ± 0.066	0.615LysHis: 0.615 ± 0.03	1.263LysIle: 1.263 ± 0.048	0.924LysLys: 0.924 ± 0.049	3.102LysLeu: 3.102 ± 0.071	0.639LysMet: 0.639 ± 0.031	0.64LysAsn: 0.64 ± 0.033	1.896LysPro: 1.896 ± 0.059	1.162LysGln: 1.162 ± 0.042	2.174LysArg: 2.174 ± 0.061	1.443LysSer: 1.443 ± 0.048	1.519LysThr: 1.519 ± 0.052	2.211LysVal: 2.211 ± 0.067	0.342LysTrp: 0.342 ± 0.021	0.632LysTyr: 0.632 ± 0.031	0.0LysXaa: 0.0 ± 0.0
Leu	14.99LeuAla: 14.99 ± 0.184	0.832LeuCys: 0.832 ± 0.029	7.011LeuAsp: 7.011 ± 0.104	5.506LeuGlu: 5.506 ± 0.105	3.344LeuPhe: 3.344 ± 0.073	8.904LeuGly: 8.904 ± 0.117	2.423LeuHis: 2.423 ± 0.058	4.063LeuIle: 4.063 ± 0.088	2.993LeuLys: 2.993 ± 0.07	11.601LeuLeu: 11.601 ± 0.189	2.375LeuMet: 2.375 ± 0.057	2.329LeuAsn: 2.329 ± 0.053	6.302LeuPro: 6.302 ± 0.105	4.037LeuGln: 4.037 ± 0.081	8.371LeuArg: 8.371 ± 0.135	5.625LeuSer: 5.625 ± 0.092	4.863LeuThr: 4.863 ± 0.089	8.19LeuVal: 8.19 ± 0.107	1.37LeuTrp: 1.37 ± 0.049	2.043LeuTyr: 2.043 ± 0.059	0.0LeuXaa: 0.0 ± 0.0
Met	2.874MetAla: 2.874 ± 0.068	0.149MetCys: 0.149 ± 0.015	1.178MetAsp: 1.178 ± 0.042	1.038MetGlu: 1.038 ± 0.042	0.711MetPhe: 0.711 ± 0.036	1.642MetGly: 1.642 ± 0.051	0.482MetHis: 0.482 ± 0.027	0.949MetIle: 0.949 ± 0.036	0.861MetLys: 0.861 ± 0.037	2.533MetLeu: 2.533 ± 0.057	0.492MetMet: 0.492 ± 0.025	0.661MetAsn: 0.661 ± 0.031	1.621MetPro: 1.621 ± 0.048	0.981MetGln: 0.981 ± 0.036	1.689MetArg: 1.689 ± 0.058	1.454MetSer: 1.454 ± 0.044	1.376MetThr: 1.376 ± 0.048	1.651MetVal: 1.651 ± 0.053	0.195MetTrp: 0.195 ± 0.017	0.412MetTyr: 0.412 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	3.259AsnAla: 3.259 ± 0.075	0.203AsnCys: 0.203 ± 0.017	1.377AsnAsp: 1.377 ± 0.036	1.207AsnGlu: 1.207 ± 0.04	0.874AsnPhe: 0.874 ± 0.039	2.243AsnGly: 2.243 ± 0.057	0.496AsnHis: 0.496 ± 0.024	1.099AsnIle: 1.099 ± 0.044	0.663AsnLys: 0.663 ± 0.034	2.532AsnLeu: 2.532 ± 0.067	0.427AsnMet: 0.427 ± 0.024	0.655AsnAsn: 0.655 ± 0.032	1.824AsnPro: 1.824 ± 0.044	0.832AsnGln: 0.832 ± 0.036	1.755AsnArg: 1.755 ± 0.053	1.08AsnSer: 1.08 ± 0.045	1.288AsnThr: 1.288 ± 0.041	1.801AsnVal: 1.801 ± 0.052	0.365AsnTrp: 0.365 ± 0.026	0.589AsnTyr: 0.589 ± 0.031	0.0AsnXaa: 0.0 ± 0.0
Pro	7.361ProAla: 7.361 ± 0.116	0.313ProCys: 0.313 ± 0.023	3.754ProAsp: 3.754 ± 0.092	3.364ProGlu: 3.364 ± 0.068	1.596ProPhe: 1.596 ± 0.049	4.991ProGly: 4.991 ± 0.089	1.161ProHis: 1.161 ± 0.041	1.865ProIle: 1.865 ± 0.048	1.309ProLys: 1.309 ± 0.042	5.251ProLeu: 5.251 ± 0.085	1.339ProMet: 1.339 ± 0.043	1.117ProAsn: 1.117 ± 0.042	2.751ProPro: 2.751 ± 0.07	1.946ProGln: 1.946 ± 0.054	3.369ProArg: 3.369 ± 0.073	2.597ProSer: 2.597 ± 0.068	2.494ProThr: 2.494 ± 0.057	4.536ProVal: 4.536 ± 0.093	0.759ProTrp: 0.759 ± 0.036	1.162ProTyr: 1.162 ± 0.045	0.0ProXaa: 0.0 ± 0.0
Gln	5.153GlnAla: 5.153 ± 0.097	0.235GlnCys: 0.235 ± 0.019	1.532GlnAsp: 1.532 ± 0.042	1.412GlnGlu: 1.412 ± 0.044	1.113GlnPhe: 1.113 ± 0.039	2.594GlnGly: 2.594 ± 0.057	0.899GlnHis: 0.899 ± 0.03	1.652GlnIle: 1.652 ± 0.054	0.853GlnLys: 0.853 ± 0.037	4.233GlnLeu: 4.233 ± 0.083	0.885GlnMet: 0.885 ± 0.035	0.697GlnAsn: 0.697 ± 0.037	2.178GlnPro: 2.178 ± 0.061	1.677GlnGln: 1.677 ± 0.052	3.479GlnArg: 3.479 ± 0.085	1.712GlnSer: 1.712 ± 0.051	1.663GlnThr: 1.663 ± 0.053	3.073GlnVal: 3.073 ± 0.063	0.651GlnTrp: 0.651 ± 0.026	0.792GlnTyr: 0.792 ± 0.039	0.0GlnXaa: 0.0 ± 0.0
Arg	8.391ArgAla: 8.391 ± 0.134	0.535ArgCys: 0.535 ± 0.023	4.725ArgAsp: 4.725 ± 0.08	4.816ArgGlu: 4.816 ± 0.085	2.969ArgPhe: 2.969 ± 0.069	5.433ArgGly: 5.433 ± 0.098	1.984ArgHis: 1.984 ± 0.061	4.0ArgIle: 4.0 ± 0.074	2.166ArgLys: 2.166 ± 0.058	8.561ArgLeu: 8.561 ± 0.144	1.859ArgMet: 1.859 ± 0.045	2.02ArgAsn: 2.02 ± 0.054	3.482ArgPro: 3.482 ± 0.076	2.978ArgGln: 2.978 ± 0.06	5.801ArgArg: 5.801 ± 0.11	3.66ArgSer: 3.66 ± 0.085	3.273ArgThr: 3.273 ± 0.074	5.387ArgVal: 5.387 ± 0.094	1.386ArgTrp: 1.386 ± 0.047	2.235ArgTyr: 2.235 ± 0.055	0.0ArgXaa: 0.0 ± 0.0
Ser	6.032SerAla: 6.032 ± 0.086	0.408SerCys: 0.408 ± 0.028	2.946SerAsp: 2.946 ± 0.067	2.489SerGlu: 2.489 ± 0.072	1.777SerPhe: 1.777 ± 0.047	5.134SerGly: 5.134 ± 0.098	1.18SerHis: 1.18 ± 0.038	2.232SerIle: 2.232 ± 0.059	1.377SerLys: 1.377 ± 0.046	5.448SerLeu: 5.448 ± 0.081	1.116SerMet: 1.116 ± 0.038	1.296SerAsn: 1.296 ± 0.037	2.835SerPro: 2.835 ± 0.06	1.802SerGln: 1.802 ± 0.055	3.955SerArg: 3.955 ± 0.089	2.735SerSer: 2.735 ± 0.069	2.728SerThr: 2.728 ± 0.064	3.714SerVal: 3.714 ± 0.079	0.731SerTrp: 0.731 ± 0.033	1.228SerTyr: 1.228 ± 0.047	0.0SerXaa: 0.0 ± 0.0
Thr	6.145ThrAla: 6.145 ± 0.099	0.358ThrCys: 0.358 ± 0.025	2.805ThrAsp: 2.805 ± 0.065	2.192ThrGlu: 2.192 ± 0.051	1.627ThrPhe: 1.627 ± 0.05	4.916ThrGly: 4.916 ± 0.093	1.063ThrHis: 1.063 ± 0.034	2.116ThrIle: 2.116 ± 0.059	0.962ThrLys: 0.962 ± 0.044	5.806ThrLeu: 5.806 ± 0.084	1.02ThrMet: 1.02 ± 0.039	1.017ThrAsn: 1.017 ± 0.046	3.254ThrPro: 3.254 ± 0.061	1.421ThrGln: 1.421 ± 0.042	3.7ThrArg: 3.7 ± 0.068	2.502ThrSer: 2.502 ± 0.06	2.617ThrThr: 2.617 ± 0.06	4.032ThrVal: 4.032 ± 0.085	0.62ThrTrp: 0.62 ± 0.026	1.057ThrTyr: 1.057 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	9.735ValAla: 9.735 ± 0.135	0.635ValCys: 0.635 ± 0.034	4.753ValAsp: 4.753 ± 0.087	4.606ValGlu: 4.606 ± 0.093	2.597ValPhe: 2.597 ± 0.056	5.752ValGly: 5.752 ± 0.106	1.59ValHis: 1.59 ± 0.047	3.685ValIle: 3.685 ± 0.068	1.867ValLys: 1.867 ± 0.061	8.429ValLeu: 8.429 ± 0.125	1.766ValMet: 1.766 ± 0.048	1.935ValAsn: 1.935 ± 0.057	3.858ValPro: 3.858 ± 0.066	2.397ValGln: 2.397 ± 0.059	5.383ValArg: 5.383 ± 0.088	3.986ValSer: 3.986 ± 0.083	3.748ValThr: 3.748 ± 0.071	6.351ValVal: 6.351 ± 0.119	0.947ValTrp: 0.947 ± 0.038	1.481ValTyr: 1.481 ± 0.052	0.0ValXaa: 0.0 ± 0.0
Trp	1.265TrpAla: 1.265 ± 0.044	0.138TrpCys: 0.138 ± 0.013	0.67TrpAsp: 0.67 ± 0.031	0.545TrpGlu: 0.545 ± 0.024	0.559TrpPhe: 0.559 ± 0.028	0.859TrpGly: 0.859 ± 0.034	0.395TrpHis: 0.395 ± 0.025	0.712TrpIle: 0.712 ± 0.031	0.434TrpLys: 0.434 ± 0.026	2.235TrpLeu: 2.235 ± 0.065	0.439TrpMet: 0.439 ± 0.025	0.476TrpAsn: 0.476 ± 0.028	0.758TrpPro: 0.758 ± 0.04	0.777TrpGln: 0.777 ± 0.036	1.274TrpArg: 1.274 ± 0.05	0.884TrpSer: 0.884 ± 0.037	0.7TrpThr: 0.7 ± 0.031	0.92TrpVal: 0.92 ± 0.038	0.299TrpTrp: 0.299 ± 0.02	0.297TrpTyr: 0.297 ± 0.023	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.67TyrAla: 2.67 ± 0.063	0.216TyrCys: 0.216 ± 0.018	1.32TyrAsp: 1.32 ± 0.043	1.169TyrGlu: 1.169 ± 0.041	0.853TyrPhe: 0.853 ± 0.03	2.034TyrGly: 2.034 ± 0.056	0.466TyrHis: 0.466 ± 0.027	0.774TyrIle: 0.774 ± 0.034	0.528TyrLys: 0.528 ± 0.028	2.478TyrLeu: 2.478 ± 0.068	0.422TyrMet: 0.422 ± 0.025	0.601TyrAsn: 0.601 ± 0.033	1.14TyrPro: 1.14 ± 0.037	0.892TyrGln: 0.892 ± 0.03	2.09TyrArg: 2.09 ± 0.054	1.15TyrSer: 1.15 ± 0.041	1.176TyrThr: 1.176 ± 0.041	1.62TyrVal: 1.62 ± 0.045	0.354TyrTrp: 0.354 ± 0.023	0.578TyrTyr: 0.578 ± 0.03	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2232 proteins (740093 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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