Amino acid dipepetide frequency for Mastomys natalensis papillomavirus (isolate African multimammate rat) (MnPV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.683AlaAla: 4.683 ± 1.778
1.081AlaCys: 1.081 ± 0.602
2.161AlaAsp: 2.161 ± 0.511
3.963AlaGlu: 3.963 ± 0.872
2.522AlaPhe: 2.522 ± 1.003
3.963AlaGly: 3.963 ± 0.5
0.72AlaHis: 0.72 ± 0.684
2.522AlaIle: 2.522 ± 0.828
1.801AlaLys: 1.801 ± 0.777
3.602AlaLeu: 3.602 ± 0.928
2.161AlaMet: 2.161 ± 1.305
1.081AlaAsn: 1.081 ± 0.664
4.323AlaPro: 4.323 ± 0.878
2.882AlaGln: 2.882 ± 0.937
6.124AlaArg: 6.124 ± 1.176
5.043AlaSer: 5.043 ± 0.732
3.963AlaThr: 3.963 ± 1.43
2.882AlaVal: 2.882 ± 0.794
1.081AlaTrp: 1.081 ± 0.358
1.801AlaTyr: 1.801 ± 0.619
0.0AlaXaa: 0.0 ± 0.0
Cys
2.882CysAla: 2.882 ± 2.145
0.72CysCys: 0.72 ± 0.629
0.72CysAsp: 0.72 ± 0.629
1.081CysGlu: 1.081 ± 0.39
0.36CysPhe: 0.36 ± 0.323
0.36CysGly: 0.36 ± 0.314
0.36CysHis: 0.36 ± 0.42
0.36CysIle: 0.36 ± 0.323
1.801CysLys: 1.801 ± 0.633
2.522CysLeu: 2.522 ± 0.886
0.72CysMet: 0.72 ± 0.497
1.081CysAsn: 1.081 ± 0.891
2.522CysPro: 2.522 ± 1.012
0.0CysGln: 0.0 ± 0.0
1.801CysArg: 1.801 ± 0.967
2.882CysSer: 2.882 ± 0.663
2.161CysThr: 2.161 ± 1.205
0.36CysVal: 0.36 ± 0.323
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.602AspAla: 3.602 ± 0.954
1.081AspCys: 1.081 ± 0.568
2.522AspAsp: 2.522 ± 0.667
4.323AspGlu: 4.323 ± 1.186
1.081AspPhe: 1.081 ± 0.527
7.565AspGly: 7.565 ± 1.395
0.0AspHis: 0.0 ± 0.0
1.441AspIle: 1.441 ± 0.629
1.801AspLys: 1.801 ± 0.474
5.403AspLeu: 5.403 ± 0.833
0.72AspMet: 0.72 ± 0.339
2.882AspAsn: 2.882 ± 1.088
6.124AspPro: 6.124 ± 1.064
0.36AspGln: 0.36 ± 0.323
2.882AspArg: 2.882 ± 0.775
6.124AspSer: 6.124 ± 1.378
2.522AspThr: 2.522 ± 0.943
3.242AspVal: 3.242 ± 0.662
0.36AspTrp: 0.36 ± 0.314
2.522AspTyr: 2.522 ± 0.476
0.0AspXaa: 0.0 ± 0.0
Glu
4.323GluAla: 4.323 ± 1.523
2.161GluCys: 2.161 ± 1.048
7.925GluAsp: 7.925 ± 0.913
6.124GluGlu: 6.124 ± 1.354
1.081GluPhe: 1.081 ± 0.97
5.043GluGly: 5.043 ± 1.347
1.081GluHis: 1.081 ± 0.494
0.72GluIle: 0.72 ± 0.393
1.801GluLys: 1.801 ± 0.792
3.602GluLeu: 3.602 ± 1.073
1.441GluMet: 1.441 ± 0.731
1.441GluAsn: 1.441 ± 1.054
4.323GluPro: 4.323 ± 1.226
1.801GluGln: 1.801 ± 0.716
2.882GluArg: 2.882 ± 1.282
5.043GluSer: 5.043 ± 0.527
6.844GluThr: 6.844 ± 0.989
3.963GluVal: 3.963 ± 1.073
0.36GluTrp: 0.36 ± 0.314
2.161GluTyr: 2.161 ± 1.153
0.0GluXaa: 0.0 ± 0.0
Phe
1.441PheAla: 1.441 ± 0.503
0.36PheCys: 0.36 ± 0.454
2.161PheAsp: 2.161 ± 0.889
2.161PheGlu: 2.161 ± 1.119
1.081PhePhe: 1.081 ± 0.584
1.081PheGly: 1.081 ± 0.653
2.161PheHis: 2.161 ± 1.264
1.081PheIle: 1.081 ± 0.97
1.441PheLys: 1.441 ± 0.731
2.882PheLeu: 2.882 ± 0.836
0.36PheMet: 0.36 ± 0.314
1.441PheAsn: 1.441 ± 0.772
1.441PhePro: 1.441 ± 0.635
1.081PheGln: 1.081 ± 0.584
1.801PheArg: 1.801 ± 0.618
3.602PheSer: 3.602 ± 0.546
1.441PheThr: 1.441 ± 0.555
0.72PheVal: 0.72 ± 0.546
0.72PheTrp: 0.72 ± 0.339
1.081PheTyr: 1.081 ± 0.363
0.0PheXaa: 0.0 ± 0.0
Gly
2.882GlyAla: 2.882 ± 0.937
0.72GlyCys: 0.72 ± 0.339
6.124GlyAsp: 6.124 ± 1.047
7.565GlyGlu: 7.565 ± 0.845
1.441GlyPhe: 1.441 ± 0.627
4.683GlyGly: 4.683 ± 2.308
2.882GlyHis: 2.882 ± 0.928
4.683GlyIle: 4.683 ± 1.231
1.441GlyLys: 1.441 ± 0.576
4.683GlyLeu: 4.683 ± 1.584
2.882GlyMet: 2.882 ± 0.703
3.963GlyAsn: 3.963 ± 1.184
3.602GlyPro: 3.602 ± 0.986
2.522GlyGln: 2.522 ± 0.941
7.925GlyArg: 7.925 ± 1.338
6.844GlySer: 6.844 ± 1.751
6.484GlyThr: 6.484 ± 1.532
2.882GlyVal: 2.882 ± 0.605
0.36GlyTrp: 0.36 ± 0.314
1.081GlyTyr: 1.081 ± 0.653
0.0GlyXaa: 0.0 ± 0.0
His
0.72HisAla: 0.72 ± 0.429
1.081HisCys: 1.081 ± 0.48
0.36HisAsp: 0.36 ± 0.319
1.081HisGlu: 1.081 ± 0.593
1.081HisPhe: 1.081 ± 0.584
3.602HisGly: 3.602 ± 0.757
1.081HisHis: 1.081 ± 0.602
0.72HisIle: 0.72 ± 0.667
0.0HisLys: 0.0 ± 0.0
2.161HisLeu: 2.161 ± 0.792
0.0HisMet: 0.0 ± 0.0
1.081HisAsn: 1.081 ± 0.38
1.081HisPro: 1.081 ± 0.653
0.72HisGln: 0.72 ± 0.684
0.0HisArg: 0.0 ± 0.0
2.882HisSer: 2.882 ± 0.764
1.801HisThr: 1.801 ± 0.736
1.441HisVal: 1.441 ± 0.555
1.081HisTrp: 1.081 ± 0.358
0.36HisTyr: 0.36 ± 0.314
0.0HisXaa: 0.0 ± 0.0
Ile
2.161IleAla: 2.161 ± 0.817
2.161IleCys: 2.161 ± 1.178
1.441IleAsp: 1.441 ± 0.555
2.161IleGlu: 2.161 ± 0.74
1.441IlePhe: 1.441 ± 0.989
3.963IleGly: 3.963 ± 1.186
0.72IleHis: 0.72 ± 0.381
1.441IleIle: 1.441 ± 0.418
1.441IleLys: 1.441 ± 0.576
5.043IleLeu: 5.043 ± 1.105
0.36IleMet: 0.36 ± 0.323
1.801IleAsn: 1.801 ± 0.892
2.882IlePro: 2.882 ± 1.001
1.081IleGln: 1.081 ± 0.568
1.801IleArg: 1.801 ± 0.811
4.323IleSer: 4.323 ± 0.974
1.801IleThr: 1.801 ± 0.717
1.801IleVal: 1.801 ± 0.892
0.0IleTrp: 0.0 ± 0.0
3.242IleTyr: 3.242 ± 1.022
0.0IleXaa: 0.0 ± 0.0
Lys
1.441LysAla: 1.441 ± 0.751
2.161LysCys: 2.161 ± 0.71
1.441LysAsp: 1.441 ± 0.277
3.242LysGlu: 3.242 ± 1.227
1.081LysPhe: 1.081 ± 0.568
1.801LysGly: 1.801 ± 0.989
0.72LysHis: 0.72 ± 0.366
2.522LysIle: 2.522 ± 0.843
2.882LysLys: 2.882 ± 1.109
2.882LysLeu: 2.882 ± 0.87
0.0LysMet: 0.0 ± 0.312
1.081LysAsn: 1.081 ± 0.556
2.522LysPro: 2.522 ± 0.436
2.161LysGln: 2.161 ± 0.886
2.522LysArg: 2.522 ± 0.676
3.963LysSer: 3.963 ± 1.454
1.801LysThr: 1.801 ± 0.684
1.801LysVal: 1.801 ± 0.646
0.36LysTrp: 0.36 ± 0.319
2.522LysTyr: 2.522 ± 0.781
0.0LysXaa: 0.0 ± 0.0
Leu
5.043LeuAla: 5.043 ± 1.49
1.441LeuCys: 1.441 ± 0.576
5.043LeuAsp: 5.043 ± 1.627
4.683LeuGlu: 4.683 ± 0.868
3.963LeuPhe: 3.963 ± 0.683
5.043LeuGly: 5.043 ± 1.645
3.242LeuHis: 3.242 ± 0.75
1.801LeuIle: 1.801 ± 0.727
3.242LeuLys: 3.242 ± 1.126
8.646LeuLeu: 8.646 ± 2.325
0.72LeuMet: 0.72 ± 0.381
1.441LeuAsn: 1.441 ± 1.257
3.963LeuPro: 3.963 ± 1.232
3.602LeuGln: 3.602 ± 0.703
6.124LeuArg: 6.124 ± 2.301
6.844LeuSer: 6.844 ± 1.001
5.403LeuThr: 5.403 ± 2.012
3.963LeuVal: 3.963 ± 0.377
0.72LeuTrp: 0.72 ± 0.393
4.323LeuTyr: 4.323 ± 1.428
0.0LeuXaa: 0.0 ± 0.0
Met
1.801MetAla: 1.801 ± 0.589
1.441MetCys: 1.441 ± 0.59
2.882MetAsp: 2.882 ± 0.699
1.441MetGlu: 1.441 ± 0.584
1.081MetPhe: 1.081 ± 0.568
1.081MetGly: 1.081 ± 0.637
0.36MetHis: 0.36 ± 0.319
1.081MetIle: 1.081 ± 0.494
1.081MetLys: 1.081 ± 0.766
0.36MetLeu: 0.36 ± 0.314
0.36MetMet: 0.36 ± 0.319
0.0MetAsn: 0.0 ± 0.0
1.081MetPro: 1.081 ± 0.692
1.081MetGln: 1.081 ± 0.664
0.72MetArg: 0.72 ± 0.4
2.522MetSer: 2.522 ± 0.93
1.081MetThr: 1.081 ± 0.658
0.72MetVal: 0.72 ± 0.629
0.0MetTrp: 0.0 ± 0.0
1.081MetTyr: 1.081 ± 0.61
0.0MetXaa: 0.0 ± 0.0
Asn
2.522AsnAla: 2.522 ± 1.486
0.36AsnCys: 0.36 ± 0.314
1.441AsnAsp: 1.441 ± 0.881
1.081AsnGlu: 1.081 ± 0.943
0.0AsnPhe: 0.0 ± 0.0
2.882AsnGly: 2.882 ± 0.588
0.0AsnHis: 0.0 ± 0.0
1.081AsnIle: 1.081 ± 0.653
1.801AsnLys: 1.801 ± 0.693
2.522AsnLeu: 2.522 ± 1.236
0.36AsnMet: 0.36 ± 0.319
1.441AsnAsn: 1.441 ± 0.881
2.882AsnPro: 2.882 ± 1.056
2.882AsnGln: 2.882 ± 1.189
3.602AsnArg: 3.602 ± 1.665
2.522AsnSer: 2.522 ± 0.436
2.161AsnThr: 2.161 ± 0.411
1.441AsnVal: 1.441 ± 0.785
0.72AsnTrp: 0.72 ± 0.429
0.72AsnTyr: 0.72 ± 0.339
0.0AsnXaa: 0.0 ± 0.0
Pro
5.403ProAla: 5.403 ± 1.257
0.36ProCys: 0.36 ± 0.454
5.403ProAsp: 5.403 ± 1.286
6.124ProGlu: 6.124 ± 1.772
1.081ProPhe: 1.081 ± 0.692
3.963ProGly: 3.963 ± 1.534
0.36ProHis: 0.36 ± 0.333
3.242ProIle: 3.242 ± 0.762
2.522ProLys: 2.522 ± 1.072
5.043ProLeu: 5.043 ± 0.592
0.72ProMet: 0.72 ± 0.629
3.242ProAsn: 3.242 ± 1.007
10.447ProPro: 10.447 ± 3.153
2.522ProGln: 2.522 ± 1.152
7.565ProArg: 7.565 ± 2.502
8.285ProSer: 8.285 ± 1.86
4.683ProThr: 4.683 ± 1.512
5.043ProVal: 5.043 ± 1.152
0.0ProTrp: 0.0 ± 0.0
2.161ProTyr: 2.161 ± 1.084
0.0ProXaa: 0.0 ± 0.0
Gln
3.602GlnAla: 3.602 ± 0.344
0.72GlnCys: 0.72 ± 0.413
1.441GlnAsp: 1.441 ± 0.418
3.242GlnGlu: 3.242 ± 0.758
0.36GlnPhe: 0.36 ± 0.323
2.882GlnGly: 2.882 ± 0.605
0.72GlnHis: 0.72 ± 0.429
2.522GlnIle: 2.522 ± 0.745
1.441GlnLys: 1.441 ± 0.467
0.72GlnLeu: 0.72 ± 0.429
1.801GlnMet: 1.801 ± 0.553
1.441GlnAsn: 1.441 ± 0.772
1.081GlnPro: 1.081 ± 0.568
1.081GlnGln: 1.081 ± 0.658
1.801GlnArg: 1.801 ± 0.989
1.801GlnSer: 1.801 ± 0.78
3.242GlnThr: 3.242 ± 0.649
3.602GlnVal: 3.602 ± 0.976
1.801GlnTrp: 1.801 ± 0.714
1.441GlnTyr: 1.441 ± 0.675
0.0GlnXaa: 0.0 ± 0.0
Arg
3.963ArgAla: 3.963 ± 0.62
2.161ArgCys: 2.161 ± 1.748
2.882ArgAsp: 2.882 ± 0.732
4.323ArgGlu: 4.323 ± 1.198
3.602ArgPhe: 3.602 ± 0.906
9.006ArgGly: 9.006 ± 2.273
2.522ArgHis: 2.522 ± 0.867
3.602ArgIle: 3.602 ± 0.839
3.242ArgLys: 3.242 ± 0.6
9.366ArgLeu: 9.366 ± 1.401
0.36ArgMet: 0.36 ± 0.323
1.801ArgAsn: 1.801 ± 0.189
6.844ArgPro: 6.844 ± 1.993
2.161ArgGln: 2.161 ± 0.676
11.167ArgArg: 11.167 ± 3.766
3.242ArgSer: 3.242 ± 0.946
6.484ArgThr: 6.484 ± 0.653
3.963ArgVal: 3.963 ± 0.881
0.72ArgTrp: 0.72 ± 0.421
2.522ArgTyr: 2.522 ± 0.838
0.0ArgXaa: 0.0 ± 0.0
Ser
3.602SerAla: 3.602 ± 0.976
0.72SerCys: 0.72 ± 0.339
4.323SerAsp: 4.323 ± 0.614
1.801SerGlu: 1.801 ± 1.154
2.882SerPhe: 2.882 ± 1.4
6.124SerGly: 6.124 ± 1.325
1.441SerHis: 1.441 ± 0.584
5.403SerIle: 5.403 ± 1.768
1.801SerLys: 1.801 ± 0.717
8.646SerLeu: 8.646 ± 0.875
3.242SerMet: 3.242 ± 1.185
4.323SerAsn: 4.323 ± 0.885
5.764SerPro: 5.764 ± 1.443
1.081SerGln: 1.081 ± 0.603
10.807SerArg: 10.807 ± 1.791
9.366SerSer: 9.366 ± 1.625
5.043SerThr: 5.043 ± 1.483
5.043SerVal: 5.043 ± 1.218
1.801SerTrp: 1.801 ± 0.566
2.522SerTyr: 2.522 ± 0.529
0.0SerXaa: 0.0 ± 0.0
Thr
4.323ThrAla: 4.323 ± 0.889
2.161ThrCys: 2.161 ± 0.744
3.242ThrAsp: 3.242 ± 0.869
2.161ThrGlu: 2.161 ± 0.727
1.441ThrPhe: 1.441 ± 0.461
5.764ThrGly: 5.764 ± 1.265
1.801ThrHis: 1.801 ± 0.467
1.801ThrIle: 1.801 ± 0.65
2.882ThrLys: 2.882 ± 0.738
3.963ThrLeu: 3.963 ± 0.677
1.081ThrMet: 1.081 ± 0.943
0.72ThrAsn: 0.72 ± 0.366
8.285ThrPro: 8.285 ± 1.83
3.242ThrGln: 3.242 ± 1.346
6.124ThrArg: 6.124 ± 0.958
5.043ThrSer: 5.043 ± 1.969
6.124ThrThr: 6.124 ± 1.192
5.403ThrVal: 5.403 ± 0.939
1.801ThrTrp: 1.801 ± 0.679
1.801ThrTyr: 1.801 ± 0.498
0.0ThrXaa: 0.0 ± 0.0
Val
2.161ValAla: 2.161 ± 0.66
1.081ValCys: 1.081 ± 0.953
2.882ValAsp: 2.882 ± 0.471
5.403ValGlu: 5.403 ± 1.051
2.161ValPhe: 2.161 ± 1.119
4.323ValGly: 4.323 ± 1.01
1.441ValHis: 1.441 ± 0.703
2.882ValIle: 2.882 ± 1.154
3.242ValLys: 3.242 ± 1.121
3.602ValLeu: 3.602 ± 1.264
2.522ValMet: 2.522 ± 0.716
0.36ValAsn: 0.36 ± 0.333
6.124ValPro: 6.124 ± 2.516
3.242ValGln: 3.242 ± 0.493
3.602ValArg: 3.602 ± 1.039
1.441ValSer: 1.441 ± 0.653
2.882ValThr: 2.882 ± 1.242
2.522ValVal: 2.522 ± 0.946
1.081ValTrp: 1.081 ± 0.554
1.081ValTyr: 1.081 ± 0.653
0.0ValXaa: 0.0 ± 0.0
Trp
0.36TrpAla: 0.36 ± 0.314
0.36TrpCys: 0.36 ± 0.323
0.36TrpAsp: 0.36 ± 0.314
0.36TrpGlu: 0.36 ± 0.319
0.36TrpPhe: 0.36 ± 0.314
1.081TrpGly: 1.081 ± 0.618
0.72TrpHis: 0.72 ± 0.413
0.36TrpIle: 0.36 ± 0.314
0.72TrpLys: 0.72 ± 0.629
1.441TrpLeu: 1.441 ± 0.679
0.36TrpMet: 0.36 ± 0.314
1.081TrpAsn: 1.081 ± 0.97
0.0TrpPro: 0.0 ± 0.0
0.72TrpGln: 0.72 ± 0.413
1.441TrpArg: 1.441 ± 0.921
1.441TrpSer: 1.441 ± 0.608
0.72TrpThr: 0.72 ± 0.366
1.441TrpVal: 1.441 ± 0.576
0.0TrpTrp: 0.0 ± 0.0
0.72TrpTyr: 0.72 ± 0.421
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.441TyrAla: 1.441 ± 0.576
0.36TyrCys: 0.36 ± 0.42
1.801TyrAsp: 1.801 ± 0.189
1.801TyrGlu: 1.801 ± 0.503
1.441TyrPhe: 1.441 ± 0.761
1.441TyrGly: 1.441 ± 0.555
0.0TyrHis: 0.0 ± 0.0
1.801TyrIle: 1.801 ± 0.189
2.882TyrLys: 2.882 ± 1.122
2.161TyrLeu: 2.161 ± 0.817
0.72TyrMet: 0.72 ± 0.366
0.72TyrAsn: 0.72 ± 0.393
2.882TyrPro: 2.882 ± 1.035
2.522TyrGln: 2.522 ± 0.797
3.242TyrArg: 3.242 ± 0.567
2.522TyrSer: 2.522 ± 0.676
2.522TyrThr: 2.522 ± 0.94
1.801TyrVal: 1.801 ± 0.736
1.081TyrTrp: 1.081 ± 0.584
2.882TyrTyr: 2.882 ± 0.95
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (2777 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski