Amino acid dipepetide frequency for Wenzhou picorna-like virus 32

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.422AlaAla: 3.422 ± 0.439
2.281AlaCys: 2.281 ± 0.095
2.662AlaAsp: 2.662 ± 0.86
3.042AlaGlu: 3.042 ± 0.067
0.76AlaPhe: 0.76 ± 0.42
6.084AlaGly: 6.084 ± 3.63
1.901AlaHis: 1.901 ± 0.468
5.703AlaIle: 5.703 ± 0.821
4.183AlaLys: 4.183 ± 1.146
4.563AlaLeu: 4.563 ± 1.356
2.281AlaMet: 2.281 ± 0.095
5.703AlaAsn: 5.703 ± 0.344
2.281AlaPro: 2.281 ± 0.095
4.183AlaGln: 4.183 ± 0.019
3.422AlaArg: 3.422 ± 0.143
4.943AlaSer: 4.943 ± 1.347
3.802AlaThr: 3.802 ± 0.812
4.563AlaVal: 4.563 ± 1.557
0.76AlaTrp: 0.76 ± 0.745
3.422AlaTyr: 3.422 ± 0.726
0.0AlaXaa: 0.0 ± 0.0
Cys
2.662CysAla: 2.662 ± 0.306
0.0CysCys: 0.0 ± 0.0
0.38CysAsp: 0.38 ± 0.21
1.141CysGlu: 1.141 ± 0.63
0.76CysPhe: 0.76 ± 0.162
0.76CysGly: 0.76 ± 0.42
1.141CysHis: 1.141 ± 0.048
0.76CysIle: 0.76 ± 0.162
1.521CysLys: 1.521 ± 0.841
0.38CysLeu: 0.38 ± 0.373
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.521CysPro: 1.521 ± 0.258
0.38CysGln: 0.38 ± 0.21
1.141CysArg: 1.141 ± 0.63
0.76CysSer: 0.76 ± 0.162
0.76CysThr: 0.76 ± 0.42
0.76CysVal: 0.76 ± 0.42
0.0CysTrp: 0.0 ± 0.0
1.141CysTyr: 1.141 ± 0.63
0.0CysXaa: 0.0 ± 0.0
Asp
4.183AspAla: 4.183 ± 1.767
1.141AspCys: 1.141 ± 0.63
4.183AspAsp: 4.183 ± 0.602
4.943AspGlu: 4.943 ± 0.984
6.084AspPhe: 6.084 ± 0.716
2.662AspGly: 2.662 ± 0.277
1.521AspHis: 1.521 ± 0.841
2.662AspIle: 2.662 ± 0.306
4.563AspLys: 4.563 ± 0.774
4.183AspLeu: 4.183 ± 1.729
1.521AspMet: 1.521 ± 0.325
2.662AspAsn: 2.662 ± 0.277
3.802AspPro: 3.802 ± 1.395
1.901AspGln: 1.901 ± 0.115
1.901AspArg: 1.901 ± 0.115
2.662AspSer: 2.662 ± 0.306
4.183AspThr: 4.183 ± 0.019
3.422AspVal: 3.422 ± 1.022
0.76AspTrp: 0.76 ± 0.162
3.422AspTyr: 3.422 ± 1.309
0.0AspXaa: 0.0 ± 0.0
Glu
5.323GluAla: 5.323 ± 0.554
2.281GluCys: 2.281 ± 1.261
3.422GluAsp: 3.422 ± 0.726
6.844GluGlu: 6.844 ± 3.2
4.563GluPhe: 4.563 ± 0.774
3.422GluGly: 3.422 ± 1.309
1.521GluHis: 1.521 ± 0.907
4.183GluIle: 4.183 ± 0.019
1.141GluLys: 1.141 ± 0.63
6.084GluLeu: 6.084 ± 0.134
0.76GluMet: 0.76 ± 0.162
3.042GluAsn: 3.042 ± 0.65
2.281GluPro: 2.281 ± 1.261
1.521GluGln: 1.521 ± 0.258
3.042GluArg: 3.042 ± 0.516
4.943GluSer: 4.943 ± 0.401
3.802GluThr: 3.802 ± 0.353
2.281GluVal: 2.281 ± 0.095
1.901GluTrp: 1.901 ± 0.468
2.281GluTyr: 2.281 ± 0.487
0.0GluXaa: 0.0 ± 0.0
Phe
3.802PheAla: 3.802 ± 1.977
0.0PheCys: 0.0 ± 0.0
4.183PheAsp: 4.183 ± 1.184
4.563PheGlu: 4.563 ± 0.191
1.901PhePhe: 1.901 ± 1.28
2.281PheGly: 2.281 ± 0.678
1.901PheHis: 1.901 ± 0.697
3.802PheIle: 3.802 ± 0.936
3.802PheLys: 3.802 ± 0.353
2.662PheLeu: 2.662 ± 0.888
0.38PheMet: 0.38 ± 0.373
3.422PheAsn: 3.422 ± 1.022
0.76PhePro: 0.76 ± 0.42
2.281PheGln: 2.281 ± 0.487
2.662PheArg: 2.662 ± 0.277
2.281PheSer: 2.281 ± 0.095
3.042PheThr: 3.042 ± 0.65
4.183PheVal: 4.183 ± 1.729
1.521PheTrp: 1.521 ± 0.325
2.662PheTyr: 2.662 ± 0.306
0.0PheXaa: 0.0 ± 0.0
Gly
4.563GlyAla: 4.563 ± 1.557
0.38GlyCys: 0.38 ± 0.21
4.563GlyAsp: 4.563 ± 1.356
3.042GlyGlu: 3.042 ± 0.067
3.042GlyPhe: 3.042 ± 0.067
4.183GlyGly: 4.183 ± 1.146
0.38GlyHis: 0.38 ± 0.21
3.042GlyIle: 3.042 ± 0.067
7.605GlyLys: 7.605 ± 1.872
4.563GlyLeu: 4.563 ± 0.774
1.521GlyMet: 1.521 ± 0.907
2.281GlyAsn: 2.281 ± 0.095
2.662GlyPro: 2.662 ± 0.86
3.042GlyGln: 3.042 ± 1.232
1.141GlyArg: 1.141 ± 0.535
5.323GlySer: 5.323 ± 0.554
4.183GlyThr: 4.183 ± 1.184
4.943GlyVal: 4.943 ± 0.764
0.76GlyTrp: 0.76 ± 0.162
2.662GlyTyr: 2.662 ± 0.277
0.0GlyXaa: 0.0 ± 0.0
His
0.38HisAla: 0.38 ± 0.373
1.141HisCys: 1.141 ± 0.535
0.0HisAsp: 0.0 ± 0.0
1.141HisGlu: 1.141 ± 0.048
1.901HisPhe: 1.901 ± 0.468
2.281HisGly: 2.281 ± 1.261
0.76HisHis: 0.76 ± 0.162
1.141HisIle: 1.141 ± 0.63
1.901HisLys: 1.901 ± 0.115
2.662HisLeu: 2.662 ± 0.888
1.521HisMet: 1.521 ± 0.751
0.76HisAsn: 0.76 ± 0.42
2.281HisPro: 2.281 ± 0.095
0.0HisGln: 0.0 ± 0.0
0.76HisArg: 0.76 ± 0.162
1.521HisSer: 1.521 ± 0.258
0.76HisThr: 0.76 ± 0.745
0.38HisVal: 0.38 ± 0.373
1.141HisTrp: 1.141 ± 0.535
1.141HisTyr: 1.141 ± 0.048
0.0HisXaa: 0.0 ± 0.0
Ile
7.605IleAla: 7.605 ± 1.041
1.521IleCys: 1.521 ± 0.841
3.422IleAsp: 3.422 ± 0.726
2.281IleGlu: 2.281 ± 0.678
2.281IlePhe: 2.281 ± 1.261
4.943IleGly: 4.943 ± 0.182
0.76IleHis: 0.76 ± 0.162
2.281IleIle: 2.281 ± 1.261
2.281IleLys: 2.281 ± 0.095
2.662IleLeu: 2.662 ± 0.277
0.76IleMet: 0.76 ± 0.42
3.802IleAsn: 3.802 ± 0.229
3.422IlePro: 3.422 ± 0.726
2.281IleGln: 2.281 ± 0.095
3.802IleArg: 3.802 ± 0.229
5.703IleSer: 5.703 ± 1.404
3.422IleThr: 3.422 ± 0.439
2.281IleVal: 2.281 ± 0.487
0.76IleTrp: 0.76 ± 0.42
1.521IleTyr: 1.521 ± 0.907
0.0IleXaa: 0.0 ± 0.0
Lys
4.183LysAla: 4.183 ± 2.311
0.76LysCys: 0.76 ± 0.42
4.943LysAsp: 4.943 ± 2.149
6.844LysGlu: 6.844 ± 2.617
2.662LysPhe: 2.662 ± 1.471
2.662LysGly: 2.662 ± 0.306
1.521LysHis: 1.521 ± 0.841
1.521LysIle: 1.521 ± 0.325
3.042LysLys: 3.042 ± 1.681
4.183LysLeu: 4.183 ± 0.563
0.76LysMet: 0.76 ± 0.42
1.901LysAsn: 1.901 ± 0.697
3.042LysPro: 3.042 ± 0.067
2.281LysGln: 2.281 ± 0.678
4.943LysArg: 4.943 ± 0.401
4.563LysSer: 4.563 ± 2.522
3.042LysThr: 3.042 ± 0.516
2.662LysVal: 2.662 ± 1.442
0.38LysTrp: 0.38 ± 0.373
1.521LysTyr: 1.521 ± 0.258
0.0LysXaa: 0.0 ± 0.0
Leu
5.323LeuAla: 5.323 ± 1.194
1.141LeuCys: 1.141 ± 0.63
3.042LeuAsp: 3.042 ± 0.516
5.703LeuGlu: 5.703 ± 0.821
3.042LeuPhe: 3.042 ± 1.098
2.281LeuGly: 2.281 ± 0.678
1.521LeuHis: 1.521 ± 0.325
6.084LeuIle: 6.084 ± 2.779
3.802LeuLys: 3.802 ± 0.936
5.323LeuLeu: 5.323 ± 0.611
2.281LeuMet: 2.281 ± 1.261
4.943LeuAsn: 4.943 ± 1.93
5.323LeuPro: 5.323 ± 0.554
2.662LeuGln: 2.662 ± 0.86
3.422LeuArg: 3.422 ± 0.726
7.985LeuSer: 7.985 ± 0.248
4.563LeuThr: 4.563 ± 0.392
4.563LeuVal: 4.563 ± 1.939
0.38LeuTrp: 0.38 ± 0.21
2.662LeuTyr: 2.662 ± 0.888
0.0LeuXaa: 0.0 ± 0.0
Met
2.281MetAla: 2.281 ± 0.487
0.38MetCys: 0.38 ± 0.21
1.141MetAsp: 1.141 ± 0.63
0.76MetGlu: 0.76 ± 0.162
0.0MetPhe: 0.0 ± 0.0
2.662MetGly: 2.662 ± 0.277
0.38MetHis: 0.38 ± 0.21
1.141MetIle: 1.141 ± 0.63
1.141MetLys: 1.141 ± 0.63
2.281MetLeu: 2.281 ± 0.678
1.521MetMet: 1.521 ± 0.325
0.76MetAsn: 0.76 ± 0.42
1.141MetPro: 1.141 ± 0.535
1.521MetGln: 1.521 ± 0.325
0.76MetArg: 0.76 ± 0.745
2.281MetSer: 2.281 ± 0.678
3.042MetThr: 3.042 ± 1.098
1.901MetVal: 1.901 ± 0.115
0.0MetTrp: 0.0 ± 0.0
0.76MetTyr: 0.76 ± 0.162
0.0MetXaa: 0.0 ± 0.0
Asn
1.521AsnAla: 1.521 ± 0.258
0.38AsnCys: 0.38 ± 0.21
3.422AsnAsp: 3.422 ± 1.022
3.802AsnGlu: 3.802 ± 0.812
3.042AsnPhe: 3.042 ± 1.815
4.183AsnGly: 4.183 ± 0.602
1.141AsnHis: 1.141 ± 0.63
4.183AsnIle: 4.183 ± 1.184
1.521AsnLys: 1.521 ± 0.841
5.703AsnLeu: 5.703 ± 1.404
0.38AsnMet: 0.38 ± 0.21
1.901AsnAsn: 1.901 ± 0.468
3.042AsnPro: 3.042 ± 1.815
1.521AsnGln: 1.521 ± 0.325
2.281AsnArg: 2.281 ± 0.487
3.042AsnSer: 3.042 ± 0.65
4.943AsnThr: 4.943 ± 0.764
4.183AsnVal: 4.183 ± 0.602
0.38AsnTrp: 0.38 ± 0.21
2.281AsnTyr: 2.281 ± 1.652
0.0AsnXaa: 0.0 ± 0.0
Pro
3.422ProAla: 3.422 ± 0.439
1.141ProCys: 1.141 ± 0.535
3.802ProAsp: 3.802 ± 0.812
3.802ProGlu: 3.802 ± 2.101
3.802ProPhe: 3.802 ± 1.977
2.281ProGly: 2.281 ± 1.652
2.281ProHis: 2.281 ± 0.487
1.901ProIle: 1.901 ± 0.115
2.281ProLys: 2.281 ± 0.095
3.802ProLeu: 3.802 ± 0.229
1.141ProMet: 1.141 ± 0.198
1.901ProAsn: 1.901 ± 0.697
2.281ProPro: 2.281 ± 1.07
3.042ProGln: 3.042 ± 0.65
1.901ProArg: 1.901 ± 1.28
1.521ProSer: 1.521 ± 0.907
3.422ProThr: 3.422 ± 1.605
4.183ProVal: 4.183 ± 1.146
0.38ProTrp: 0.38 ± 0.373
0.76ProTyr: 0.76 ± 0.162
0.0ProXaa: 0.0 ± 0.0
Gln
0.76GlnAla: 0.76 ± 0.162
0.38GlnCys: 0.38 ± 0.373
1.901GlnAsp: 1.901 ± 1.863
2.662GlnGlu: 2.662 ± 0.86
2.662GlnPhe: 2.662 ± 0.888
1.901GlnGly: 1.901 ± 0.115
0.76GlnHis: 0.76 ± 0.162
2.662GlnIle: 2.662 ± 0.277
2.662GlnLys: 2.662 ± 0.888
2.281GlnLeu: 2.281 ± 0.095
1.141GlnMet: 1.141 ± 0.63
1.141GlnAsn: 1.141 ± 0.048
0.38GlnPro: 0.38 ± 0.373
1.901GlnGln: 1.901 ± 0.468
1.521GlnArg: 1.521 ± 0.841
3.802GlnSer: 3.802 ± 0.812
3.042GlnThr: 3.042 ± 1.681
4.183GlnVal: 4.183 ± 0.602
0.76GlnTrp: 0.76 ± 0.162
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.281ArgAla: 2.281 ± 0.678
0.38ArgCys: 0.38 ± 0.21
4.183ArgAsp: 4.183 ± 1.729
1.521ArgGlu: 1.521 ± 0.325
1.521ArgPhe: 1.521 ± 0.325
3.422ArgGly: 3.422 ± 0.439
0.76ArgHis: 0.76 ± 0.42
3.802ArgIle: 3.802 ± 0.812
2.662ArgLys: 2.662 ± 0.306
4.183ArgLeu: 4.183 ± 0.563
1.521ArgMet: 1.521 ± 0.258
4.183ArgAsn: 4.183 ± 0.563
3.042ArgPro: 3.042 ± 1.232
1.521ArgGln: 1.521 ± 0.325
3.422ArgArg: 3.422 ± 0.726
1.901ArgSer: 1.901 ± 0.697
1.901ArgThr: 1.901 ± 1.28
1.901ArgVal: 1.901 ± 0.115
0.76ArgTrp: 0.76 ± 0.162
0.76ArgTyr: 0.76 ± 0.162
0.0ArgXaa: 0.0 ± 0.0
Ser
4.183SerAla: 4.183 ± 1.184
1.521SerCys: 1.521 ± 0.841
6.844SerAsp: 6.844 ± 0.296
4.183SerGlu: 4.183 ± 0.602
1.901SerPhe: 1.901 ± 0.115
6.844SerGly: 6.844 ± 0.879
2.281SerHis: 2.281 ± 0.678
5.703SerIle: 5.703 ± 0.239
2.662SerLys: 2.662 ± 1.471
4.563SerLeu: 4.563 ± 0.774
1.901SerMet: 1.901 ± 0.115
0.76SerAsn: 0.76 ± 0.42
1.521SerPro: 1.521 ± 0.258
2.662SerGln: 2.662 ± 0.888
2.662SerArg: 2.662 ± 0.277
4.183SerSer: 4.183 ± 0.019
4.943SerThr: 4.943 ± 3.095
4.563SerVal: 4.563 ± 0.974
0.38SerTrp: 0.38 ± 0.373
3.422SerTyr: 3.422 ± 0.439
0.0SerXaa: 0.0 ± 0.0
Thr
4.183ThrAla: 4.183 ± 0.019
0.38ThrCys: 0.38 ± 0.21
3.042ThrAsp: 3.042 ± 0.067
1.901ThrGlu: 1.901 ± 0.115
4.943ThrPhe: 4.943 ± 0.764
4.943ThrGly: 4.943 ± 0.764
0.76ThrHis: 0.76 ± 0.42
4.183ThrIle: 4.183 ± 0.602
2.281ThrLys: 2.281 ± 0.487
4.943ThrLeu: 4.943 ± 0.401
3.422ThrMet: 3.422 ± 0.439
4.563ThrAsn: 4.563 ± 0.974
5.323ThrPro: 5.323 ± 2.302
0.76ThrGln: 0.76 ± 0.42
1.901ThrArg: 1.901 ± 0.697
3.802ThrSer: 3.802 ± 0.812
4.183ThrThr: 4.183 ± 2.35
5.703ThrVal: 5.703 ± 1.509
1.141ThrTrp: 1.141 ± 0.63
1.901ThrTyr: 1.901 ± 0.468
0.0ThrXaa: 0.0 ± 0.0
Val
4.943ValAla: 4.943 ± 0.764
0.76ValCys: 0.76 ± 0.162
4.183ValAsp: 4.183 ± 1.184
4.943ValGlu: 4.943 ± 0.182
4.183ValPhe: 4.183 ± 1.767
2.662ValGly: 2.662 ± 0.306
1.141ValHis: 1.141 ± 0.048
2.281ValIle: 2.281 ± 0.095
4.943ValLys: 4.943 ± 0.984
4.943ValLeu: 4.943 ± 0.401
1.901ValMet: 1.901 ± 1.051
6.084ValAsn: 6.084 ± 1.299
3.802ValPro: 3.802 ± 2.56
1.141ValGln: 1.141 ± 0.63
3.042ValArg: 3.042 ± 1.098
3.422ValSer: 3.422 ± 1.605
2.281ValThr: 2.281 ± 0.487
4.183ValVal: 4.183 ± 0.602
0.76ValTrp: 0.76 ± 0.42
2.281ValTyr: 2.281 ± 0.095
0.0ValXaa: 0.0 ± 0.0
Trp
1.141TrpAla: 1.141 ± 0.535
0.0TrpCys: 0.0 ± 0.0
1.521TrpAsp: 1.521 ± 0.325
0.38TrpGlu: 0.38 ± 0.21
0.76TrpPhe: 0.76 ± 0.42
0.76TrpGly: 0.76 ± 0.162
0.38TrpHis: 0.38 ± 0.373
0.38TrpIle: 0.38 ± 0.21
0.76TrpLys: 0.76 ± 0.162
1.141TrpLeu: 1.141 ± 0.63
0.38TrpMet: 0.38 ± 0.373
0.76TrpAsn: 0.76 ± 0.745
0.0TrpPro: 0.0 ± 0.0
1.141TrpGln: 1.141 ± 0.048
1.141TrpArg: 1.141 ± 0.048
0.38TrpSer: 0.38 ± 0.21
1.901TrpThr: 1.901 ± 0.697
0.0TrpVal: 0.0 ± 0.0
0.38TrpTrp: 0.38 ± 0.21
0.38TrpTyr: 0.38 ± 0.21
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.802TyrAla: 3.802 ± 2.101
0.0TyrCys: 0.0 ± 0.0
1.521TyrAsp: 1.521 ± 0.258
1.141TyrGlu: 1.141 ± 0.048
2.281TyrPhe: 2.281 ± 0.487
2.662TyrGly: 2.662 ± 0.306
0.76TyrHis: 0.76 ± 0.42
0.38TyrIle: 0.38 ± 0.373
2.662TyrLys: 2.662 ± 1.471
4.943TyrLeu: 4.943 ± 0.764
0.38TyrMet: 0.38 ± 0.21
2.281TyrAsn: 2.281 ± 1.07
1.521TyrPro: 1.521 ± 0.325
0.76TyrGln: 0.76 ± 0.42
0.76TyrArg: 0.76 ± 0.745
2.662TyrSer: 2.662 ± 0.86
3.042TyrThr: 3.042 ± 1.098
3.042TyrVal: 3.042 ± 0.65
0.38TyrTrp: 0.38 ± 0.373
1.901TyrTyr: 1.901 ± 1.051
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2631 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski