Amino acid dipepetide frequency for Rotavirus X (isolate RVX/Human/Bangladesh/NADRV-B219/2002/GXP[X]) (RV ADRV-N) (Rotavirus (isolate novel adult diarrhea rotavirus-B219))

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.873AlaAla: 3.873 ± 1.02
0.528AlaCys: 0.528 ± 0.372
2.64AlaAsp: 2.64 ± 0.927
4.401AlaGlu: 4.401 ± 0.944
2.64AlaPhe: 2.64 ± 0.687
1.936AlaGly: 1.936 ± 1.026
0.352AlaHis: 0.352 ± 0.184
5.105AlaIle: 5.105 ± 1.019
4.225AlaLys: 4.225 ± 0.843
4.753AlaLeu: 4.753 ± 0.575
1.584AlaMet: 1.584 ± 0.476
3.697AlaAsn: 3.697 ± 0.997
1.584AlaPro: 1.584 ± 0.546
2.464AlaGln: 2.464 ± 0.505
2.112AlaArg: 2.112 ± 0.7
4.929AlaSer: 4.929 ± 0.684
5.105AlaThr: 5.105 ± 0.749
2.816AlaVal: 2.816 ± 0.757
0.528AlaTrp: 0.528 ± 0.293
1.936AlaTyr: 1.936 ± 0.586
0.0AlaXaa: 0.0 ± 0.0
Cys
0.352CysAla: 0.352 ± 0.205
0.176CysCys: 0.176 ± 0.165
0.88CysAsp: 0.88 ± 0.603
1.76CysGlu: 1.76 ± 0.573
0.528CysPhe: 0.528 ± 0.217
1.232CysGly: 1.232 ± 0.671
0.0CysHis: 0.0 ± 0.0
1.056CysIle: 1.056 ± 0.426
0.704CysLys: 0.704 ± 0.318
0.704CysLeu: 0.704 ± 0.437
0.528CysMet: 0.528 ± 0.372
0.88CysAsn: 0.88 ± 0.406
0.176CysPro: 0.176 ± 0.216
0.528CysGln: 0.528 ± 0.362
0.176CysArg: 0.176 ± 0.22
0.528CysSer: 0.528 ± 0.353
0.528CysThr: 0.528 ± 0.376
0.528CysVal: 0.528 ± 0.221
0.0CysTrp: 0.0 ± 0.0
0.704CysTyr: 0.704 ± 0.372
0.0CysXaa: 0.0 ± 0.0
Asp
3.168AspAla: 3.168 ± 1.136
0.352AspCys: 0.352 ± 0.268
3.344AspAsp: 3.344 ± 0.558
4.225AspGlu: 4.225 ± 1.086
1.232AspPhe: 1.232 ± 0.424
2.464AspGly: 2.464 ± 0.547
0.352AspHis: 0.352 ± 0.221
5.105AspIle: 5.105 ± 0.99
4.401AspLys: 4.401 ± 0.871
6.161AspLeu: 6.161 ± 1.189
1.056AspMet: 1.056 ± 0.401
4.225AspAsn: 4.225 ± 0.834
2.112AspPro: 2.112 ± 0.75
2.112AspGln: 2.112 ± 0.547
4.401AspArg: 4.401 ± 0.867
4.753AspSer: 4.753 ± 1.315
2.992AspThr: 2.992 ± 0.634
4.225AspVal: 4.225 ± 1.012
0.88AspTrp: 0.88 ± 0.469
2.816AspTyr: 2.816 ± 0.668
0.0AspXaa: 0.0 ± 0.0
Glu
3.344GluAla: 3.344 ± 1.188
0.528GluCys: 0.528 ± 0.372
2.816GluAsp: 2.816 ± 0.562
3.521GluGlu: 3.521 ± 0.719
3.521GluPhe: 3.521 ± 1.02
2.464GluGly: 2.464 ± 0.85
1.056GluHis: 1.056 ± 0.487
4.929GluIle: 4.929 ± 0.97
4.225GluLys: 4.225 ± 0.708
5.281GluLeu: 5.281 ± 0.644
2.288GluMet: 2.288 ± 0.569
4.577GluAsn: 4.577 ± 1.033
1.936GluPro: 1.936 ± 0.619
2.464GluGln: 2.464 ± 0.614
1.936GluArg: 1.936 ± 0.526
5.809GluSer: 5.809 ± 1.332
3.344GluThr: 3.344 ± 1.075
2.64GluVal: 2.64 ± 0.795
0.352GluTrp: 0.352 ± 0.174
2.464GluTyr: 2.464 ± 0.804
0.0GluXaa: 0.0 ± 0.0
Phe
1.936PheAla: 1.936 ± 0.315
0.88PheCys: 0.88 ± 0.536
4.401PheAsp: 4.401 ± 1.172
3.344PheGlu: 3.344 ± 0.604
1.408PhePhe: 1.408 ± 0.468
3.168PheGly: 3.168 ± 0.705
1.232PheHis: 1.232 ± 0.581
3.168PheIle: 3.168 ± 0.841
3.344PheLys: 3.344 ± 0.875
2.64PheLeu: 2.64 ± 0.599
0.528PheMet: 0.528 ± 0.335
2.816PheAsn: 2.816 ± 0.461
1.408PhePro: 1.408 ± 0.497
1.232PheGln: 1.232 ± 0.262
2.992PheArg: 2.992 ± 0.783
4.049PheSer: 4.049 ± 0.702
2.992PheThr: 2.992 ± 0.52
1.936PheVal: 1.936 ± 0.616
0.352PheTrp: 0.352 ± 0.26
1.76PheTyr: 1.76 ± 0.583
0.0PheXaa: 0.0 ± 0.0
Gly
2.992GlyAla: 2.992 ± 0.782
0.528GlyCys: 0.528 ± 0.279
1.76GlyAsp: 1.76 ± 0.56
1.936GlyGlu: 1.936 ± 0.625
2.288GlyPhe: 2.288 ± 0.488
2.288GlyGly: 2.288 ± 0.866
1.76GlyHis: 1.76 ± 0.628
4.049GlyIle: 4.049 ± 0.469
2.64GlyLys: 2.64 ± 0.815
3.168GlyLeu: 3.168 ± 1.006
0.88GlyMet: 0.88 ± 0.235
3.521GlyAsn: 3.521 ± 0.841
1.056GlyPro: 1.056 ± 0.404
1.056GlyGln: 1.056 ± 0.448
1.584GlyArg: 1.584 ± 0.495
1.408GlySer: 1.408 ± 0.248
2.64GlyThr: 2.64 ± 0.702
2.64GlyVal: 2.64 ± 0.689
0.176GlyTrp: 0.176 ± 0.216
1.584GlyTyr: 1.584 ± 0.371
0.0GlyXaa: 0.0 ± 0.0
His
1.76HisAla: 1.76 ± 0.496
0.176HisCys: 0.176 ± 0.165
1.232HisAsp: 1.232 ± 0.34
1.056HisGlu: 1.056 ± 0.312
0.528HisPhe: 0.528 ± 0.293
0.88HisGly: 0.88 ± 0.391
0.176HisHis: 0.176 ± 0.165
1.584HisIle: 1.584 ± 0.688
0.528HisLys: 0.528 ± 0.346
2.112HisLeu: 2.112 ± 0.655
0.88HisMet: 0.88 ± 0.272
0.528HisAsn: 0.528 ± 0.236
0.704HisPro: 0.704 ± 0.312
0.528HisGln: 0.528 ± 0.345
0.88HisArg: 0.88 ± 0.335
2.288HisSer: 2.288 ± 0.496
1.056HisThr: 1.056 ± 0.426
0.704HisVal: 0.704 ± 0.298
0.176HisTrp: 0.176 ± 0.191
0.528HisTyr: 0.528 ± 0.315
0.0HisXaa: 0.0 ± 0.0
Ile
5.457IleAla: 5.457 ± 1.159
1.232IleCys: 1.232 ± 0.552
5.457IleAsp: 5.457 ± 0.682
6.337IleGlu: 6.337 ± 0.993
4.049IlePhe: 4.049 ± 0.825
3.697IleGly: 3.697 ± 0.79
1.408IleHis: 1.408 ± 0.293
7.041IleIle: 7.041 ± 1.309
6.513IleLys: 6.513 ± 1.17
6.161IleLeu: 6.161 ± 1.052
1.76IleMet: 1.76 ± 0.432
5.809IleAsn: 5.809 ± 0.803
3.344IlePro: 3.344 ± 0.365
4.225IleGln: 4.225 ± 0.874
4.929IleArg: 4.929 ± 1.174
6.865IleSer: 6.865 ± 0.715
4.753IleThr: 4.753 ± 0.733
4.401IleVal: 4.401 ± 1.045
0.352IleTrp: 0.352 ± 0.236
2.464IleTyr: 2.464 ± 0.725
0.0IleXaa: 0.0 ± 0.0
Lys
3.521LysAla: 3.521 ± 0.659
1.232LysCys: 1.232 ± 0.558
2.64LysAsp: 2.64 ± 1.046
4.929LysGlu: 4.929 ± 0.969
2.288LysPhe: 2.288 ± 0.886
1.76LysGly: 1.76 ± 0.692
0.704LysHis: 0.704 ± 0.257
8.449LysIle: 8.449 ± 0.938
6.513LysLys: 6.513 ± 0.978
6.161LysLeu: 6.161 ± 0.775
1.408LysMet: 1.408 ± 0.455
4.225LysAsn: 4.225 ± 0.955
1.408LysPro: 1.408 ± 0.497
2.64LysGln: 2.64 ± 0.422
4.049LysArg: 4.049 ± 0.75
3.344LysSer: 3.344 ± 0.641
4.929LysThr: 4.929 ± 0.974
3.697LysVal: 3.697 ± 0.527
0.88LysTrp: 0.88 ± 0.317
3.168LysTyr: 3.168 ± 1.011
0.0LysXaa: 0.0 ± 0.0
Leu
5.105LeuAla: 5.105 ± 0.887
1.408LeuCys: 1.408 ± 0.737
5.985LeuAsp: 5.985 ± 0.751
3.873LeuGlu: 3.873 ± 1.235
4.753LeuPhe: 4.753 ± 0.866
2.464LeuGly: 2.464 ± 0.677
2.112LeuHis: 2.112 ± 0.451
6.337LeuIle: 6.337 ± 0.824
5.457LeuLys: 5.457 ± 0.808
8.625LeuLeu: 8.625 ± 0.875
2.288LeuMet: 2.288 ± 0.637
5.457LeuAsn: 5.457 ± 1.192
3.168LeuPro: 3.168 ± 0.75
4.225LeuGln: 4.225 ± 0.776
4.049LeuArg: 4.049 ± 0.805
7.393LeuSer: 7.393 ± 0.949
6.337LeuThr: 6.337 ± 0.523
3.873LeuVal: 3.873 ± 0.715
0.352LeuTrp: 0.352 ± 0.203
3.344LeuTyr: 3.344 ± 1.135
0.0LeuXaa: 0.0 ± 0.0
Met
1.76MetAla: 1.76 ± 0.392
0.528MetCys: 0.528 ± 0.272
1.232MetAsp: 1.232 ± 0.547
1.936MetGlu: 1.936 ± 0.443
1.584MetPhe: 1.584 ± 0.579
1.408MetGly: 1.408 ± 0.405
0.176MetHis: 0.176 ± 0.14
2.64MetIle: 2.64 ± 0.557
1.056MetLys: 1.056 ± 0.306
2.112MetLeu: 2.112 ± 0.633
1.232MetMet: 1.232 ± 0.428
2.112MetAsn: 2.112 ± 0.485
0.88MetPro: 0.88 ± 0.278
0.704MetGln: 0.704 ± 0.38
1.232MetArg: 1.232 ± 0.56
2.816MetSer: 2.816 ± 0.711
1.584MetThr: 1.584 ± 0.703
1.584MetVal: 1.584 ± 0.409
0.0MetTrp: 0.0 ± 0.0
0.88MetTyr: 0.88 ± 0.533
0.0MetXaa: 0.0 ± 0.0
Asn
5.281AsnAla: 5.281 ± 1.429
0.704AsnCys: 0.704 ± 0.323
5.105AsnAsp: 5.105 ± 1.284
3.168AsnGlu: 3.168 ± 0.445
2.464AsnPhe: 2.464 ± 0.41
2.112AsnGly: 2.112 ± 0.477
1.584AsnHis: 1.584 ± 0.634
4.929AsnIle: 4.929 ± 0.802
3.873AsnLys: 3.873 ± 1.228
5.985AsnLeu: 5.985 ± 0.562
2.288AsnMet: 2.288 ± 0.615
4.049AsnAsn: 4.049 ± 1.043
2.288AsnPro: 2.288 ± 0.881
2.288AsnGln: 2.288 ± 0.645
4.049AsnArg: 4.049 ± 0.93
5.985AsnSer: 5.985 ± 1.107
3.873AsnThr: 3.873 ± 0.852
3.697AsnVal: 3.697 ± 0.657
0.88AsnTrp: 0.88 ± 0.268
3.697AsnTyr: 3.697 ± 1.192
0.0AsnXaa: 0.0 ± 0.0
Pro
1.936ProAla: 1.936 ± 0.368
0.352ProCys: 0.352 ± 0.245
1.584ProAsp: 1.584 ± 0.427
1.936ProGlu: 1.936 ± 0.403
1.232ProPhe: 1.232 ± 0.288
1.408ProGly: 1.408 ± 0.458
0.704ProHis: 0.704 ± 0.43
2.64ProIle: 2.64 ± 0.541
2.64ProLys: 2.64 ± 0.764
3.168ProLeu: 3.168 ± 0.766
0.88ProMet: 0.88 ± 0.378
3.344ProAsn: 3.344 ± 0.694
1.232ProPro: 1.232 ± 0.491
2.112ProGln: 2.112 ± 0.406
0.88ProArg: 0.88 ± 0.347
2.992ProSer: 2.992 ± 0.62
2.112ProThr: 2.112 ± 0.783
3.168ProVal: 3.168 ± 0.765
0.352ProTrp: 0.352 ± 0.202
2.112ProTyr: 2.112 ± 0.588
0.0ProXaa: 0.0 ± 0.0
Gln
0.704GlnAla: 0.704 ± 0.329
0.704GlnCys: 0.704 ± 0.408
1.232GlnAsp: 1.232 ± 0.296
1.936GlnGlu: 1.936 ± 0.614
2.992GlnPhe: 2.992 ± 0.749
1.232GlnGly: 1.232 ± 0.312
1.232GlnHis: 1.232 ± 0.355
4.049GlnIle: 4.049 ± 0.74
2.464GlnLys: 2.464 ± 0.704
5.457GlnLeu: 5.457 ± 0.79
0.704GlnMet: 0.704 ± 0.282
2.64GlnAsn: 2.64 ± 0.561
2.288GlnPro: 2.288 ± 0.345
1.936GlnGln: 1.936 ± 0.508
2.64GlnArg: 2.64 ± 0.78
1.76GlnSer: 1.76 ± 0.5
1.76GlnThr: 1.76 ± 0.369
2.464GlnVal: 2.464 ± 0.465
0.176GlnTrp: 0.176 ± 0.138
1.232GlnTyr: 1.232 ± 0.502
0.0GlnXaa: 0.0 ± 0.0
Arg
3.168ArgAla: 3.168 ± 0.828
0.88ArgCys: 0.88 ± 0.399
4.225ArgAsp: 4.225 ± 0.941
3.521ArgGlu: 3.521 ± 0.625
2.464ArgPhe: 2.464 ± 0.883
1.232ArgGly: 1.232 ± 0.367
0.528ArgHis: 0.528 ± 0.293
3.873ArgIle: 3.873 ± 0.663
3.168ArgLys: 3.168 ± 0.654
3.168ArgLeu: 3.168 ± 0.5
2.816ArgMet: 2.816 ± 0.705
2.992ArgAsn: 2.992 ± 0.427
1.936ArgPro: 1.936 ± 0.688
3.168ArgGln: 3.168 ± 0.544
2.288ArgArg: 2.288 ± 0.887
2.992ArgSer: 2.992 ± 0.57
4.225ArgThr: 4.225 ± 0.72
2.288ArgVal: 2.288 ± 0.523
0.176ArgTrp: 0.176 ± 0.156
1.056ArgTyr: 1.056 ± 0.37
0.0ArgXaa: 0.0 ± 0.0
Ser
4.225SerAla: 4.225 ± 1.001
0.704SerCys: 0.704 ± 0.229
4.577SerAsp: 4.577 ± 0.991
4.049SerGlu: 4.049 ± 0.934
4.049SerPhe: 4.049 ± 0.718
2.64SerGly: 2.64 ± 0.332
1.232SerHis: 1.232 ± 0.423
7.745SerIle: 7.745 ± 1.394
4.929SerLys: 4.929 ± 0.91
8.273SerLeu: 8.273 ± 1.199
0.88SerMet: 0.88 ± 0.436
4.049SerAsn: 4.049 ± 0.698
3.521SerPro: 3.521 ± 0.594
3.521SerGln: 3.521 ± 0.765
3.344SerArg: 3.344 ± 0.416
5.281SerSer: 5.281 ± 0.637
5.633SerThr: 5.633 ± 0.989
5.633SerVal: 5.633 ± 1.51
0.88SerTrp: 0.88 ± 0.52
2.288SerTyr: 2.288 ± 0.892
0.0SerXaa: 0.0 ± 0.0
Thr
2.112ThrAla: 2.112 ± 0.599
0.352ThrCys: 0.352 ± 0.236
4.577ThrAsp: 4.577 ± 0.564
2.112ThrGlu: 2.112 ± 0.749
2.992ThrPhe: 2.992 ± 0.941
2.112ThrGly: 2.112 ± 0.697
1.232ThrHis: 1.232 ± 0.383
7.393ThrIle: 7.393 ± 0.852
5.457ThrLys: 5.457 ± 0.994
4.225ThrLeu: 4.225 ± 1.083
2.288ThrMet: 2.288 ± 0.582
4.577ThrAsn: 4.577 ± 0.97
2.816ThrPro: 2.816 ± 0.568
1.936ThrGln: 1.936 ± 0.494
2.64ThrArg: 2.64 ± 0.759
5.985ThrSer: 5.985 ± 0.88
3.697ThrThr: 3.697 ± 0.677
3.873ThrVal: 3.873 ± 0.695
0.528ThrTrp: 0.528 ± 0.376
3.168ThrTyr: 3.168 ± 0.72
0.0ThrXaa: 0.0 ± 0.0
Val
3.697ValAla: 3.697 ± 0.828
0.528ValCys: 0.528 ± 0.256
3.873ValAsp: 3.873 ± 0.761
2.816ValGlu: 2.816 ± 0.469
3.521ValPhe: 3.521 ± 0.714
2.816ValGly: 2.816 ± 1.083
0.88ValHis: 0.88 ± 0.454
2.64ValIle: 2.64 ± 0.777
2.64ValLys: 2.64 ± 0.761
5.281ValLeu: 5.281 ± 0.777
1.584ValMet: 1.584 ± 0.452
3.521ValAsn: 3.521 ± 0.66
3.168ValPro: 3.168 ± 0.512
1.232ValGln: 1.232 ± 0.514
3.873ValArg: 3.873 ± 0.824
4.225ValSer: 4.225 ± 0.642
3.873ValThr: 3.873 ± 1.166
2.64ValVal: 2.64 ± 1.019
0.528ValTrp: 0.528 ± 0.342
2.112ValTyr: 2.112 ± 0.407
0.0ValXaa: 0.0 ± 0.0
Trp
0.528TrpAla: 0.528 ± 0.273
0.0TrpCys: 0.0 ± 0.0
0.176TrpAsp: 0.176 ± 0.138
0.352TrpGlu: 0.352 ± 0.205
0.0TrpPhe: 0.0 ± 0.0
0.176TrpGly: 0.176 ± 0.165
0.176TrpHis: 0.176 ± 0.156
0.528TrpIle: 0.528 ± 0.281
0.88TrpLys: 0.88 ± 0.345
1.232TrpLeu: 1.232 ± 0.307
0.176TrpMet: 0.176 ± 0.165
0.704TrpAsn: 0.704 ± 0.229
0.176TrpPro: 0.176 ± 0.191
0.176TrpGln: 0.176 ± 0.138
0.704TrpArg: 0.704 ± 0.325
0.528TrpSer: 0.528 ± 0.192
0.528TrpThr: 0.528 ± 0.407
0.704TrpVal: 0.704 ± 0.388
0.0TrpTrp: 0.0 ± 0.0
0.176TrpTyr: 0.176 ± 0.215
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.288TyrAla: 2.288 ± 0.491
0.176TyrCys: 0.176 ± 0.149
2.64TyrAsp: 2.64 ± 0.399
2.288TyrGlu: 2.288 ± 0.777
1.232TyrPhe: 1.232 ± 0.451
2.464TyrGly: 2.464 ± 0.61
1.408TyrHis: 1.408 ± 0.298
2.992TyrIle: 2.992 ± 0.691
2.288TyrLys: 2.288 ± 0.736
1.936TyrLeu: 1.936 ± 0.597
1.232TyrMet: 1.232 ± 0.478
4.577TyrAsn: 4.577 ± 0.779
1.584TyrPro: 1.584 ± 0.578
1.056TyrGln: 1.056 ± 0.444
1.408TyrArg: 1.408 ± 0.45
3.521TyrSer: 3.521 ± 0.708
2.112TyrThr: 2.112 ± 0.599
1.936TyrVal: 1.936 ± 0.577
0.352TyrTrp: 0.352 ± 0.215
1.584TyrTyr: 1.584 ± 0.461
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 11 proteins (5682 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski