Amino acid dipepetide frequency for Oryza rufipogon (Brownbeard rice) (Asian wild rice)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.013AlaAla: 15.013 ± 0.062	1.577AlaCys: 1.577 ± 0.01	4.222AlaAsp: 4.222 ± 0.017	4.844AlaGlu: 4.844 ± 0.02	2.887AlaPhe: 2.887 ± 0.015	6.756AlaGly: 6.756 ± 0.027	1.737AlaHis: 1.737 ± 0.01	3.738AlaIle: 3.738 ± 0.017	3.637AlaLys: 3.637 ± 0.018	7.723AlaLeu: 7.723 ± 0.028	2.318AlaMet: 2.318 ± 0.013	2.537AlaAsn: 2.537 ± 0.013	4.729AlaPro: 4.729 ± 0.019	2.365AlaGln: 2.365 ± 0.013	5.575AlaArg: 5.575 ± 0.024	7.451AlaSer: 7.451 ± 0.023	4.913AlaThr: 4.913 ± 0.018	6.786AlaVal: 6.786 ± 0.024	1.02AlaTrp: 1.02 ± 0.008	1.875AlaTyr: 1.875 ± 0.011	0.003AlaXaa: 0.003 ± 0.0
Cys	1.357CysAla: 1.357 ± 0.01	0.629CysCys: 0.629 ± 0.007	0.918CysAsp: 0.918 ± 0.008	0.833CysGlu: 0.833 ± 0.008	0.826CysPhe: 0.826 ± 0.008	1.542CysGly: 1.542 ± 0.011	0.547CysHis: 0.547 ± 0.005	0.944CysIle: 0.944 ± 0.007	0.959CysLys: 0.959 ± 0.008	1.856CysLeu: 1.856 ± 0.009	0.455CysMet: 0.455 ± 0.005	0.739CysAsn: 0.739 ± 0.007	1.036CysPro: 1.036 ± 0.011	0.585CysGln: 0.585 ± 0.006	1.362CysArg: 1.362 ± 0.011	1.917CysSer: 1.917 ± 0.011	0.945CysThr: 0.945 ± 0.006	1.151CysVal: 1.151 ± 0.008	0.275CysTrp: 0.275 ± 0.004	0.527CysTyr: 0.527 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	4.749AspAla: 4.749 ± 0.019	0.937AspCys: 0.937 ± 0.007	4.458AspAsp: 4.458 ± 0.022	3.929AspGlu: 3.929 ± 0.018	1.95AspPhe: 1.95 ± 0.012	4.814AspGly: 4.814 ± 0.02	1.307AspHis: 1.307 ± 0.01	2.708AspIle: 2.708 ± 0.015	2.376AspLys: 2.376 ± 0.013	4.841AspLeu: 4.841 ± 0.017	1.414AspMet: 1.414 ± 0.011	1.819AspAsn: 1.819 ± 0.012	2.615AspPro: 2.615 ± 0.013	1.585AspGln: 1.585 ± 0.01	2.688AspArg: 2.688 ± 0.013	3.652AspSer: 3.652 ± 0.018	2.211AspThr: 2.211 ± 0.012	3.769AspVal: 3.769 ± 0.017	0.676AspTrp: 0.676 ± 0.006	1.378AspTyr: 1.378 ± 0.009	0.001AspXaa: 0.001 ± 0.0
Glu	5.333GluAla: 5.333 ± 0.023	0.869GluCys: 0.869 ± 0.007	3.633GluAsp: 3.633 ± 0.018	5.907GluGlu: 5.907 ± 0.029	1.986GluPhe: 1.986 ± 0.01	3.754GluGly: 3.754 ± 0.016	1.381GluHis: 1.381 ± 0.01	2.989GluIle: 2.989 ± 0.014	3.657GluLys: 3.657 ± 0.022	5.883GluLeu: 5.883 ± 0.025	1.691GluMet: 1.691 ± 0.01	2.242GluAsn: 2.242 ± 0.012	2.236GluPro: 2.236 ± 0.013	2.175GluGln: 2.175 ± 0.013	3.647GluArg: 3.647 ± 0.017	3.709GluSer: 3.709 ± 0.019	2.537GluThr: 2.537 ± 0.015	4.025GluVal: 4.025 ± 0.018	0.762GluTrp: 0.762 ± 0.007	1.471GluTyr: 1.471 ± 0.009	0.001GluXaa: 0.001 ± 0.0
Phe	2.754PheAla: 2.754 ± 0.014	0.781PheCys: 0.781 ± 0.007	2.089PheAsp: 2.089 ± 0.011	1.779PheGlu: 1.779 ± 0.011	1.646PhePhe: 1.646 ± 0.012	2.785PheGly: 2.785 ± 0.018	0.996PheHis: 0.996 ± 0.007	1.606PheIle: 1.606 ± 0.01	1.447PheLys: 1.447 ± 0.009	3.821PheLeu: 3.821 ± 0.019	0.847PheMet: 0.847 ± 0.007	1.307PheAsn: 1.307 ± 0.01	1.872PhePro: 1.872 ± 0.011	1.218PheGln: 1.218 ± 0.008	1.975PheArg: 1.975 ± 0.011	3.269PheSer: 3.269 ± 0.014	1.715PheThr: 1.715 ± 0.01	2.568PheVal: 2.568 ± 0.013	0.503PheTrp: 0.503 ± 0.005	1.026PheTyr: 1.026 ± 0.009	0.001PheXaa: 0.001 ± 0.0
Gly	6.165GlyAla: 6.165 ± 0.023	1.542GlyCys: 1.542 ± 0.011	4.297GlyAsp: 4.297 ± 0.016	4.301GlyGlu: 4.301 ± 0.018	2.766GlyPhe: 2.766 ± 0.014	9.458GlyGly: 9.458 ± 0.053	1.799GlyHis: 1.799 ± 0.012	3.153GlyIle: 3.153 ± 0.015	3.553GlyLys: 3.553 ± 0.018	5.815GlyLeu: 5.815 ± 0.021	1.672GlyMet: 1.672 ± 0.01	2.746GlyAsn: 2.746 ± 0.015	2.649GlyPro: 2.649 ± 0.014	2.14GlyGln: 2.14 ± 0.014	5.014GlyArg: 5.014 ± 0.025	6.071GlySer: 6.071 ± 0.024	3.322GlyThr: 3.322 ± 0.014	4.775GlyVal: 4.775 ± 0.018	1.05GlyTrp: 1.05 ± 0.009	2.01GlyTyr: 2.01 ± 0.014	0.002GlyXaa: 0.002 ± 0.0
His	1.948HisAla: 1.948 ± 0.012	0.573HisCys: 0.573 ± 0.006	1.306HisAsp: 1.306 ± 0.01	1.236HisGlu: 1.236 ± 0.009	0.891HisPhe: 0.891 ± 0.007	2.203HisGly: 2.203 ± 0.013	1.161HisHis: 1.161 ± 0.01	1.095HisIle: 1.095 ± 0.009	0.975HisLys: 0.975 ± 0.008	2.668HisLeu: 2.668 ± 0.015	0.571HisMet: 0.571 ± 0.006	0.819HisAsn: 0.819 ± 0.007	1.576HisPro: 1.576 ± 0.011	0.952HisGln: 0.952 ± 0.008	1.85HisArg: 1.85 ± 0.012	1.714HisSer: 1.714 ± 0.009	0.984HisThr: 0.984 ± 0.008	1.625HisVal: 1.625 ± 0.01	0.302HisTrp: 0.302 ± 0.004	0.652HisTyr: 0.652 ± 0.007	0.0HisXaa: 0.0 ± 0.0
Ile	3.549IleAla: 3.549 ± 0.016	0.98IleCys: 0.98 ± 0.007	2.549IleAsp: 2.549 ± 0.013	2.498IleGlu: 2.498 ± 0.016	1.734IlePhe: 1.734 ± 0.012	3.095IleGly: 3.095 ± 0.016	1.158IleHis: 1.158 ± 0.009	2.277IleIle: 2.277 ± 0.014	2.25IleLys: 2.25 ± 0.013	4.351IleLeu: 4.351 ± 0.019	1.002IleMet: 1.002 ± 0.008	1.723IleAsn: 1.723 ± 0.01	2.526IlePro: 2.526 ± 0.017	1.583IleGln: 1.583 ± 0.012	2.453IleArg: 2.453 ± 0.014	3.979IleSer: 3.979 ± 0.016	2.304IleThr: 2.304 ± 0.013	3.054IleVal: 3.054 ± 0.016	0.629IleTrp: 0.629 ± 0.006	1.257IleTyr: 1.257 ± 0.009	0.001IleXaa: 0.001 ± 0.0
Lys	3.651LysAla: 3.651 ± 0.019	0.823LysCys: 0.823 ± 0.008	2.629LysAsp: 2.629 ± 0.015	3.597LysGlu: 3.597 ± 0.018	1.569LysPhe: 1.569 ± 0.011	2.989LysGly: 2.989 ± 0.015	1.137LysHis: 1.137 ± 0.008	2.557LysIle: 2.557 ± 0.014	3.517LysLys: 3.517 ± 0.021	4.869LysLeu: 4.869 ± 0.024	1.25LysMet: 1.25 ± 0.009	1.966LysAsn: 1.966 ± 0.01	2.278LysPro: 2.278 ± 0.014	1.841LysGln: 1.841 ± 0.011	3.092LysArg: 3.092 ± 0.014	3.377LysSer: 3.377 ± 0.015	2.212LysThr: 2.212 ± 0.013	3.112LysVal: 3.112 ± 0.014	0.601LysTrp: 0.601 ± 0.007	1.293LysTyr: 1.293 ± 0.01	0.0LysXaa: 0.0 ± 0.0
Leu	8.167LeuAla: 8.167 ± 0.025	1.839LeuCys: 1.839 ± 0.009	5.071LeuAsp: 5.071 ± 0.018	5.664LeuGlu: 5.664 ± 0.026	3.366LeuPhe: 3.366 ± 0.017	5.86LeuGly: 5.86 ± 0.018	2.832LeuHis: 2.832 ± 0.016	3.75LeuIle: 3.75 ± 0.018	4.704LeuLys: 4.704 ± 0.02	10.692LeuLeu: 10.692 ± 0.031	2.015LeuMet: 2.015 ± 0.01	3.053LeuAsn: 3.053 ± 0.014	5.993LeuPro: 5.993 ± 0.022	4.037LeuGln: 4.037 ± 0.021	6.47LeuArg: 6.47 ± 0.024	7.836LeuSer: 7.836 ± 0.028	4.254LeuThr: 4.254 ± 0.019	6.477LeuVal: 6.477 ± 0.021	1.143LeuTrp: 1.143 ± 0.009	2.274LeuTyr: 2.274 ± 0.015	0.002LeuXaa: 0.002 ± 0.0
Met	2.829MetAla: 2.829 ± 0.014	0.352MetCys: 0.352 ± 0.005	1.449MetAsp: 1.449 ± 0.009	1.866MetGlu: 1.866 ± 0.012	0.753MetPhe: 0.753 ± 0.006	1.527MetGly: 1.527 ± 0.01	0.577MetHis: 0.577 ± 0.006	1.012MetIle: 1.012 ± 0.008	1.279MetLys: 1.279 ± 0.009	2.23MetLeu: 2.23 ± 0.011	0.677MetMet: 0.677 ± 0.008	0.844MetAsn: 0.844 ± 0.008	1.284MetPro: 1.284 ± 0.009	0.897MetGln: 0.897 ± 0.009	1.376MetArg: 1.376 ± 0.008	1.77MetSer: 1.77 ± 0.01	1.055MetThr: 1.055 ± 0.008	1.725MetVal: 1.725 ± 0.008	0.302MetTrp: 0.302 ± 0.004	0.568MetTyr: 0.568 ± 0.005	0.001MetXaa: 0.001 ± 0.0
Asn	2.57AsnAla: 2.57 ± 0.013	0.731AsnCys: 0.731 ± 0.009	1.732AsnAsp: 1.732 ± 0.011	1.862AsnGlu: 1.862 ± 0.012	1.427AsnPhe: 1.427 ± 0.01	2.806AsnGly: 2.806 ± 0.015	0.899AsnHis: 0.899 ± 0.008	2.013AsnIle: 2.013 ± 0.013	1.818AsnLys: 1.818 ± 0.012	3.808AsnLeu: 3.808 ± 0.024	0.987AsnMet: 0.987 ± 0.008	1.724AsnAsn: 1.724 ± 0.017	1.859AsnPro: 1.859 ± 0.012	1.259AsnGln: 1.259 ± 0.009	1.773AsnArg: 1.773 ± 0.01	2.872AsnSer: 2.872 ± 0.015	1.687AsnThr: 1.687 ± 0.012	2.221AsnVal: 2.221 ± 0.012	0.447AsnTrp: 0.447 ± 0.005	0.992AsnTyr: 0.992 ± 0.008	0.0AsnXaa: 0.0 ± 0.0
Pro	5.286ProAla: 5.286 ± 0.022	0.987ProCys: 0.987 ± 0.008	2.698ProAsp: 2.698 ± 0.015	3.171ProGlu: 3.171 ± 0.016	1.841ProPhe: 1.841 ± 0.014	3.216ProGly: 3.216 ± 0.015	1.298ProHis: 1.298 ± 0.009	1.931ProIle: 1.931 ± 0.011	2.217ProLys: 2.217 ± 0.014	4.684ProLeu: 4.684 ± 0.016	1.103ProMet: 1.103 ± 0.008	1.848ProAsn: 1.848 ± 0.013	6.152ProPro: 6.152 ± 0.038	1.745ProGln: 1.745 ± 0.012	3.518ProArg: 3.518 ± 0.016	5.517ProSer: 5.517 ± 0.026	2.862ProThr: 2.862 ± 0.016	3.398ProVal: 3.398 ± 0.014	0.699ProTrp: 0.699 ± 0.007	1.245ProTyr: 1.245 ± 0.009	0.003ProXaa: 0.003 ± 0.0
Gln	2.542GlnAla: 2.542 ± 0.015	0.599GlnCys: 0.599 ± 0.006	1.575GlnAsp: 1.575 ± 0.009	2.224GlnGlu: 2.224 ± 0.013	1.135GlnPhe: 1.135 ± 0.007	2.126GlnGly: 2.126 ± 0.012	0.99GlnHis: 0.99 ± 0.009	1.625GlnIle: 1.625 ± 0.011	1.781GlnLys: 1.781 ± 0.012	3.533GlnLeu: 3.533 ± 0.017	0.908GlnMet: 0.908 ± 0.009	1.318GlnAsn: 1.318 ± 0.01	1.915GlnPro: 1.915 ± 0.012	2.197GlnGln: 2.197 ± 0.022	2.258GlnArg: 2.258 ± 0.011	2.385GlnSer: 2.385 ± 0.012	1.425GlnThr: 1.425 ± 0.011	2.113GlnVal: 2.113 ± 0.013	0.466GlnTrp: 0.466 ± 0.005	0.859GlnTyr: 0.859 ± 0.008	0.001GlnXaa: 0.001 ± 0.0
Arg	5.116ArgAla: 5.116 ± 0.022	1.404ArgCys: 1.404 ± 0.01	2.972ArgAsp: 2.972 ± 0.014	3.532ArgGlu: 3.532 ± 0.017	2.198ArgPhe: 2.198 ± 0.011	4.538ArgGly: 4.538 ± 0.021	1.779ArgHis: 1.779 ± 0.011	2.68ArgIle: 2.68 ± 0.013	3.256ArgLys: 3.256 ± 0.017	6.12ArgLeu: 6.12 ± 0.021	1.542ArgMet: 1.542 ± 0.009	2.131ArgAsn: 2.131 ± 0.012	3.392ArgPro: 3.392 ± 0.018	2.112ArgGln: 2.112 ± 0.012	7.481ArgArg: 7.481 ± 0.034	4.991ArgSer: 4.991 ± 0.019	2.669ArgThr: 2.669 ± 0.011	3.812ArgVal: 3.812 ± 0.018	1.135ArgTrp: 1.135 ± 0.009	1.57ArgTyr: 1.57 ± 0.01	0.001ArgXaa: 0.001 ± 0.0
Ser	6.531SerAla: 6.531 ± 0.022	1.778SerCys: 1.778 ± 0.01	3.999SerAsp: 3.999 ± 0.017	3.944SerGlu: 3.944 ± 0.016	3.265SerPhe: 3.265 ± 0.014	6.035SerGly: 6.035 ± 0.021	1.85SerHis: 1.85 ± 0.01	3.725SerIle: 3.725 ± 0.018	3.715SerLys: 3.715 ± 0.017	7.946SerLeu: 7.946 ± 0.03	2.023SerMet: 2.023 ± 0.011	3.144SerAsn: 3.144 ± 0.016	5.155SerPro: 5.155 ± 0.024	2.444SerGln: 2.444 ± 0.012	4.805SerArg: 4.805 ± 0.021	10.532SerSer: 10.532 ± 0.043	4.519SerThr: 4.519 ± 0.02	4.793SerVal: 4.793 ± 0.017	1.154SerTrp: 1.154 ± 0.009	2.11SerTyr: 2.11 ± 0.012	0.001SerXaa: 0.001 ± 0.0
Thr	4.474ThrAla: 4.474 ± 0.019	0.943ThrCys: 0.943 ± 0.008	2.274ThrAsp: 2.274 ± 0.011	2.525ThrGlu: 2.525 ± 0.014	1.718ThrPhe: 1.718 ± 0.011	3.498ThrGly: 3.498 ± 0.016	0.982ThrHis: 0.982 ± 0.008	2.356ThrIle: 2.356 ± 0.013	2.222ThrLys: 2.222 ± 0.013	4.196ThrLeu: 4.196 ± 0.018	1.279ThrMet: 1.279 ± 0.009	1.78ThrAsn: 1.78 ± 0.011	2.816ThrPro: 2.816 ± 0.016	1.32ThrGln: 1.32 ± 0.009	2.664ThrArg: 2.664 ± 0.012	4.362ThrSer: 4.362 ± 0.019	3.301ThrThr: 3.301 ± 0.016	3.462ThrVal: 3.462 ± 0.015	0.628ThrTrp: 0.628 ± 0.007	1.25ThrTyr: 1.25 ± 0.01	0.001ThrXaa: 0.001 ± 0.0
Val	6.844ValAla: 6.844 ± 0.025	1.17ValCys: 1.17 ± 0.01	3.888ValAsp: 3.888 ± 0.016	4.115ValGlu: 4.115 ± 0.019	2.474ValPhe: 2.474 ± 0.014	4.545ValGly: 4.545 ± 0.018	1.661ValHis: 1.661 ± 0.011	2.883ValIle: 2.883 ± 0.015	3.068ValLys: 3.068 ± 0.013	6.585ValLeu: 6.585 ± 0.024	1.544ValMet: 1.544 ± 0.009	2.066ValAsn: 2.066 ± 0.012	3.538ValPro: 3.538 ± 0.017	2.226ValGln: 2.226 ± 0.011	3.778ValArg: 3.778 ± 0.016	5.036ValSer: 5.036 ± 0.017	3.266ValThr: 3.266 ± 0.015	5.766ValVal: 5.766 ± 0.022	0.814ValTrp: 0.814 ± 0.007	1.764ValTyr: 1.764 ± 0.011	0.001ValXaa: 0.001 ± 0.0
Trp	0.977TrpAla: 0.977 ± 0.008	0.287TrpCys: 0.287 ± 0.005	0.667TrpAsp: 0.667 ± 0.006	0.743TrpGlu: 0.743 ± 0.006	0.475TrpPhe: 0.475 ± 0.005	0.792TrpGly: 0.792 ± 0.008	0.311TrpHis: 0.311 ± 0.004	0.628TrpIle: 0.628 ± 0.006	0.742TrpLys: 0.742 ± 0.008	1.282TrpLeu: 1.282 ± 0.01	0.379TrpMet: 0.379 ± 0.004	0.575TrpAsn: 0.575 ± 0.006	0.622TrpPro: 0.622 ± 0.006	0.459TrpGln: 0.459 ± 0.005	1.205TrpArg: 1.205 ± 0.009	1.041TrpSer: 1.041 ± 0.007	0.668TrpThr: 0.668 ± 0.006	0.799TrpVal: 0.799 ± 0.007	0.301TrpTrp: 0.301 ± 0.004	0.33TrpTyr: 0.33 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.849TyrAla: 1.849 ± 0.013	0.604TyrCys: 0.604 ± 0.006	1.452TyrAsp: 1.452 ± 0.009	1.318TyrGlu: 1.318 ± 0.008	1.096TyrPhe: 1.096 ± 0.008	1.957TyrGly: 1.957 ± 0.014	0.7TyrHis: 0.7 ± 0.007	1.28TyrIle: 1.28 ± 0.011	1.183TyrLys: 1.183 ± 0.009	2.596TyrLeu: 2.596 ± 0.014	0.695TyrMet: 0.695 ± 0.006	1.107TyrAsn: 1.107 ± 0.009	1.178TyrPro: 1.178 ± 0.009	0.83TyrGln: 0.83 ± 0.007	1.446TyrArg: 1.446 ± 0.011	1.986TyrSer: 1.986 ± 0.013	1.205TyrThr: 1.205 ± 0.011	1.597TyrVal: 1.597 ± 0.011	0.374TyrTrp: 0.374 ± 0.005	0.905TyrTyr: 0.905 ± 0.009	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.003XaaAla: 0.003 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.002XaaGly: 0.002 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.001XaaMet: 0.001 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.002XaaPro: 0.002 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.002XaaArg: 0.002 ± 0.0	0.002XaaSer: 0.002 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.001XaaTrp: 0.001 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.01XaaXaa: 0.01 ± 0.004

Statistics based on 45598 proteins (18680246 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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