Amino acid dipepetide frequency for Phaeocystis globosa virus 14T

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.237AlaAla: 3.237 ± 0.278
0.506AlaCys: 0.506 ± 0.065
2.79AlaAsp: 2.79 ± 0.186
2.805AlaGlu: 2.805 ± 0.171
1.652AlaPhe: 1.652 ± 0.119
2.656AlaGly: 2.656 ± 0.228
0.774AlaHis: 0.774 ± 0.085
3.579AlaIle: 3.579 ± 0.18
3.646AlaLys: 3.646 ± 0.231
3.654AlaLeu: 3.654 ± 0.189
1.28AlaMet: 1.28 ± 0.132
3.155AlaAsn: 3.155 ± 0.167
1.444AlaPro: 1.444 ± 0.138
1.258AlaGln: 1.258 ± 0.105
1.615AlaArg: 1.615 ± 0.127
3.319AlaSer: 3.319 ± 0.24
3.103AlaThr: 3.103 ± 0.209
2.738AlaVal: 2.738 ± 0.165
0.379AlaTrp: 0.379 ± 0.059
1.793AlaTyr: 1.793 ± 0.129
0.0AlaXaa: 0.0 ± 0.0
Cys
0.566CysAla: 0.566 ± 0.064
0.469CysCys: 0.469 ± 0.064
1.124CysAsp: 1.124 ± 0.103
0.826CysGlu: 0.826 ± 0.089
0.632CysPhe: 0.632 ± 0.075
1.079CysGly: 1.079 ± 0.102
0.268CysHis: 0.268 ± 0.051
1.079CysIle: 1.079 ± 0.09
1.741CysLys: 1.741 ± 0.168
1.042CysLeu: 1.042 ± 0.094
0.335CysMet: 0.335 ± 0.042
1.191CysAsn: 1.191 ± 0.105
0.551CysPro: 0.551 ± 0.07
0.298CysGln: 0.298 ± 0.05
0.424CysArg: 0.424 ± 0.059
1.012CysSer: 1.012 ± 0.093
0.58CysThr: 0.58 ± 0.083
0.878CysVal: 0.878 ± 0.077
0.156CysTrp: 0.156 ± 0.036
0.744CysTyr: 0.744 ± 0.083
0.0CysXaa: 0.0 ± 0.0
Asp
3.051AspAla: 3.051 ± 0.196
0.945AspCys: 0.945 ± 0.096
5.239AspAsp: 5.239 ± 0.362
5.142AspGlu: 5.142 ± 0.315
2.976AspPhe: 2.976 ± 0.185
3.43AspGly: 3.43 ± 0.209
0.677AspHis: 0.677 ± 0.073
6.347AspIle: 6.347 ± 0.3
6.213AspLys: 6.213 ± 0.28
5.09AspLeu: 5.09 ± 0.234
1.615AspMet: 1.615 ± 0.11
5.722AspAsn: 5.722 ± 0.278
1.525AspPro: 1.525 ± 0.115
1.153AspGln: 1.153 ± 0.097
1.548AspArg: 1.548 ± 0.099
3.594AspSer: 3.594 ± 0.176
4.122AspThr: 4.122 ± 0.181
3.609AspVal: 3.609 ± 0.269
0.469AspTrp: 0.469 ± 0.064
3.378AspTyr: 3.378 ± 0.174
0.0AspXaa: 0.0 ± 0.0
Glu
2.671GluAla: 2.671 ± 0.183
0.945GluCys: 0.945 ± 0.087
3.929GluAsp: 3.929 ± 0.219
5.164GluGlu: 5.164 ± 0.512
3.103GluPhe: 3.103 ± 0.156
2.002GluGly: 2.002 ± 0.137
1.079GluHis: 1.079 ± 0.098
4.911GluIle: 4.911 ± 0.187
5.908GluLys: 5.908 ± 0.318
5.596GluLeu: 5.596 ± 0.238
1.63GluMet: 1.63 ± 0.132
5.157GluAsn: 5.157 ± 0.224
2.389GluPro: 2.389 ± 0.185
1.942GluGln: 1.942 ± 0.141
2.225GluArg: 2.225 ± 0.151
2.865GluSer: 2.865 ± 0.173
4.316GluThr: 4.316 ± 0.216
2.887GluVal: 2.887 ± 0.17
0.499GluTrp: 0.499 ± 0.065
3.051GluTyr: 3.051 ± 0.192
0.0GluXaa: 0.0 ± 0.0
Phe
1.778PheAla: 1.778 ± 0.158
0.566PheCys: 0.566 ± 0.06
2.999PheAsp: 2.999 ± 0.184
2.098PheGlu: 2.098 ± 0.114
1.764PhePhe: 1.764 ± 0.139
2.232PheGly: 2.232 ± 0.176
0.737PheHis: 0.737 ± 0.075
3.944PheIle: 3.944 ± 0.212
4.115PheLys: 4.115 ± 0.189
3.557PheLeu: 3.557 ± 0.195
1.295PheMet: 1.295 ± 0.106
4.1PheAsn: 4.1 ± 0.253
1.086PhePro: 1.086 ± 0.11
1.109PheGln: 1.109 ± 0.095
1.109PheArg: 1.109 ± 0.103
3.058PheSer: 3.058 ± 0.155
2.805PheThr: 2.805 ± 0.215
2.634PheVal: 2.634 ± 0.138
0.342PheTrp: 0.342 ± 0.06
2.195PheTyr: 2.195 ± 0.145
0.0PheXaa: 0.0 ± 0.0
Gly
2.337GlyAla: 2.337 ± 0.203
0.811GlyCys: 0.811 ± 0.094
3.2GlyAsp: 3.2 ± 0.263
2.746GlyGlu: 2.746 ± 0.146
2.284GlyPhe: 2.284 ± 0.175
3.535GlyGly: 3.535 ± 0.319
0.752GlyHis: 0.752 ± 0.094
4.093GlyIle: 4.093 ± 0.261
4.249GlyLys: 4.249 ± 0.204
3.981GlyLeu: 3.981 ± 0.244
1.019GlyMet: 1.019 ± 0.091
3.959GlyAsn: 3.959 ± 0.218
1.057GlyPro: 1.057 ± 0.09
1.31GlyGln: 1.31 ± 0.127
1.451GlyArg: 1.451 ± 0.163
3.691GlySer: 3.691 ± 0.269
2.909GlyThr: 2.909 ± 0.296
3.058GlyVal: 3.058 ± 0.157
0.35GlyTrp: 0.35 ± 0.056
2.039GlyTyr: 2.039 ± 0.143
0.0GlyXaa: 0.0 ± 0.0
His
0.766HisAla: 0.766 ± 0.078
0.335HisCys: 0.335 ± 0.05
0.96HisAsp: 0.96 ± 0.077
0.856HisGlu: 0.856 ± 0.085
0.729HisPhe: 0.729 ± 0.078
0.885HisGly: 0.885 ± 0.096
0.551HisHis: 0.551 ± 0.068
1.741HisIle: 1.741 ± 0.126
1.793HisLys: 1.793 ± 0.159
1.451HisLeu: 1.451 ± 0.101
0.58HisMet: 0.58 ± 0.077
1.771HisAsn: 1.771 ± 0.16
0.67HisPro: 0.67 ± 0.061
0.588HisGln: 0.588 ± 0.07
0.61HisArg: 0.61 ± 0.069
1.339HisSer: 1.339 ± 0.112
1.146HisThr: 1.146 ± 0.15
0.915HisVal: 0.915 ± 0.116
0.179HisTrp: 0.179 ± 0.037
0.826HisTyr: 0.826 ± 0.079
0.0HisXaa: 0.0 ± 0.0
Ile
3.237IleAla: 3.237 ± 0.198
1.31IleCys: 1.31 ± 0.111
6.429IleAsp: 6.429 ± 0.273
5.35IleGlu: 5.35 ± 0.173
3.661IlePhe: 3.661 ± 0.182
3.698IleGly: 3.698 ± 0.292
1.853IleHis: 1.853 ± 0.117
7.285IleIle: 7.285 ± 0.32
7.969IleLys: 7.969 ± 0.345
6.6IleLeu: 6.6 ± 0.254
2.329IleMet: 2.329 ± 0.153
7.858IleAsn: 7.858 ± 0.313
2.954IlePro: 2.954 ± 0.163
2.716IleGln: 2.716 ± 0.148
2.143IleArg: 2.143 ± 0.161
5.96IleSer: 5.96 ± 0.255
5.372IleThr: 5.372 ± 0.256
4.39IleVal: 4.39 ± 0.182
0.603IleTrp: 0.603 ± 0.073
4.331IleTyr: 4.331 ± 0.182
0.0IleXaa: 0.0 ± 0.0
Lys
3.832LysAla: 3.832 ± 0.229
1.473LysCys: 1.473 ± 0.134
5.432LysAsp: 5.432 ± 0.264
5.484LysGlu: 5.484 ± 0.285
3.825LysPhe: 3.825 ± 0.2
3.14LysGly: 3.14 ± 0.177
2.24LysHis: 2.24 ± 0.133
7.493LysIle: 7.493 ± 0.287
10.343LysLys: 10.343 ± 0.484
8.379LysLeu: 8.379 ± 0.336
2.277LysMet: 2.277 ± 0.162
7.798LysAsn: 7.798 ± 0.34
3.021LysPro: 3.021 ± 0.19
3.334LysGln: 3.334 ± 0.214
2.582LysArg: 2.582 ± 0.177
5.633LysSer: 5.633 ± 0.253
6.064LysThr: 6.064 ± 0.29
4.003LysVal: 4.003 ± 0.213
0.692LysTrp: 0.692 ± 0.064
5.387LysTyr: 5.387 ± 0.263
0.0LysXaa: 0.0 ± 0.0
Leu
3.594LeuAla: 3.594 ± 0.211
1.28LeuCys: 1.28 ± 0.109
5.194LeuAsp: 5.194 ± 0.201
5.119LeuGlu: 5.119 ± 0.224
4.07LeuPhe: 4.07 ± 0.194
3.527LeuGly: 3.527 ± 0.21
1.518LeuHis: 1.518 ± 0.123
7.151LeuIle: 7.151 ± 0.261
7.225LeuLys: 7.225 ± 0.309
6.697LeuLeu: 6.697 ± 0.283
2.284LeuMet: 2.284 ± 0.159
7.039LeuAsn: 7.039 ± 0.278
2.954LeuPro: 2.954 ± 0.167
2.396LeuGln: 2.396 ± 0.134
2.403LeuArg: 2.403 ± 0.133
5.707LeuSer: 5.707 ± 0.299
4.658LeuThr: 4.658 ± 0.17
3.892LeuVal: 3.892 ± 0.19
0.573LeuTrp: 0.573 ± 0.066
4.026LeuTyr: 4.026 ± 0.19
0.0LeuXaa: 0.0 ± 0.0
Met
1.28MetAla: 1.28 ± 0.111
0.394MetCys: 0.394 ± 0.058
1.823MetAsp: 1.823 ± 0.122
1.883MetGlu: 1.883 ± 0.126
1.101MetPhe: 1.101 ± 0.107
1.488MetGly: 1.488 ± 0.121
0.26MetHis: 0.26 ± 0.049
1.778MetIle: 1.778 ± 0.119
2.165MetLys: 2.165 ± 0.152
1.927MetLeu: 1.927 ± 0.13
0.856MetMet: 0.856 ± 0.09
1.994MetAsn: 1.994 ± 0.151
0.774MetPro: 0.774 ± 0.085
0.588MetGln: 0.588 ± 0.07
1.034MetArg: 1.034 ± 0.094
2.128MetSer: 2.128 ± 0.128
1.399MetThr: 1.399 ± 0.113
1.272MetVal: 1.272 ± 0.114
0.275MetTrp: 0.275 ± 0.056
1.168MetTyr: 1.168 ± 0.099
0.0MetXaa: 0.0 ± 0.0
Asn
3.215AsnAla: 3.215 ± 0.169
1.064AsnCys: 1.064 ± 0.105
4.695AsnAsp: 4.695 ± 0.224
4.651AsnGlu: 4.651 ± 0.229
3.304AsnPhe: 3.304 ± 0.201
3.907AsnGly: 3.907 ± 0.297
1.533AsnHis: 1.533 ± 0.172
9.182AsnIle: 9.182 ± 0.379
8.632AsnLys: 8.632 ± 0.377
7.062AsnLeu: 7.062 ± 0.273
2.463AsnMet: 2.463 ± 0.155
8.885AsnAsn: 8.885 ± 0.381
2.783AsnPro: 2.783 ± 0.167
2.225AsnGln: 2.225 ± 0.147
2.307AsnArg: 2.307 ± 0.145
5.305AsnSer: 5.305 ± 0.284
5.618AsnThr: 5.618 ± 0.253
4.093AsnVal: 4.093 ± 0.194
0.655AsnTrp: 0.655 ± 0.078
4.584AsnTyr: 4.584 ± 0.266
0.0AsnXaa: 0.0 ± 0.0
Pro
1.704ProAla: 1.704 ± 0.131
0.439ProCys: 0.439 ± 0.065
2.389ProAsp: 2.389 ± 0.124
2.545ProGlu: 2.545 ± 0.174
1.317ProPhe: 1.317 ± 0.11
1.384ProGly: 1.384 ± 0.1
0.774ProHis: 0.774 ± 0.084
2.627ProIle: 2.627 ± 0.132
2.634ProLys: 2.634 ± 0.159
2.225ProLeu: 2.225 ± 0.138
0.655ProMet: 0.655 ± 0.073
2.143ProAsn: 2.143 ± 0.136
1.339ProPro: 1.339 ± 0.134
0.915ProGln: 0.915 ± 0.087
0.9ProArg: 0.9 ± 0.078
2.158ProSer: 2.158 ± 0.124
2.106ProThr: 2.106 ± 0.127
2.232ProVal: 2.232 ± 0.172
0.238ProTrp: 0.238 ± 0.041
1.57ProTyr: 1.57 ± 0.102
0.0ProXaa: 0.0 ± 0.0
Gln
1.295GlnAla: 1.295 ± 0.102
0.35GlnCys: 0.35 ± 0.053
1.466GlnAsp: 1.466 ± 0.117
1.853GlnGlu: 1.853 ± 0.128
1.458GlnPhe: 1.458 ± 0.107
1.079GlnGly: 1.079 ± 0.098
0.685GlnHis: 0.685 ± 0.079
2.389GlnIle: 2.389 ± 0.113
2.448GlnLys: 2.448 ± 0.15
2.456GlnLeu: 2.456 ± 0.142
0.811GlnMet: 0.811 ± 0.083
2.396GlnAsn: 2.396 ± 0.171
0.908GlnPro: 0.908 ± 0.094
1.183GlnGln: 1.183 ± 0.114
0.9GlnArg: 0.9 ± 0.097
1.845GlnSer: 1.845 ± 0.133
2.017GlnThr: 2.017 ± 0.188
1.362GlnVal: 1.362 ± 0.116
0.179GlnTrp: 0.179 ± 0.034
1.347GlnTyr: 1.347 ± 0.122
0.0GlnXaa: 0.0 ± 0.0
Arg
1.354ArgAla: 1.354 ± 0.095
0.618ArgCys: 0.618 ± 0.08
1.697ArgAsp: 1.697 ± 0.129
2.188ArgGlu: 2.188 ± 0.147
1.339ArgPhe: 1.339 ± 0.105
1.555ArgGly: 1.555 ± 0.105
0.677ArgHis: 0.677 ± 0.085
2.307ArgIle: 2.307 ± 0.135
2.679ArgLys: 2.679 ± 0.189
2.456ArgLeu: 2.456 ± 0.157
0.766ArgMet: 0.766 ± 0.076
2.173ArgAsn: 2.173 ± 0.126
1.265ArgPro: 1.265 ± 0.106
0.997ArgGln: 0.997 ± 0.086
1.295ArgArg: 1.295 ± 0.147
1.771ArgSer: 1.771 ± 0.123
1.793ArgThr: 1.793 ± 0.138
1.555ArgVal: 1.555 ± 0.11
0.342ArgTrp: 0.342 ± 0.05
1.317ArgTyr: 1.317 ± 0.114
0.0ArgXaa: 0.0 ± 0.0
Ser
3.363SerAla: 3.363 ± 0.218
1.019SerCys: 1.019 ± 0.104
4.264SerAsp: 4.264 ± 0.263
2.902SerGlu: 2.902 ± 0.169
3.029SerPhe: 3.029 ± 0.219
4.182SerGly: 4.182 ± 0.292
1.444SerHis: 1.444 ± 0.092
5.983SerIle: 5.983 ± 0.211
5.439SerLys: 5.439 ± 0.283
5.41SerLeu: 5.41 ± 0.193
1.592SerMet: 1.592 ± 0.127
5.849SerAsn: 5.849 ± 0.315
1.719SerPro: 1.719 ± 0.125
1.987SerGln: 1.987 ± 0.142
2.277SerArg: 2.277 ± 0.145
4.904SerSer: 4.904 ± 0.295
3.616SerThr: 3.616 ± 0.193
3.884SerVal: 3.884 ± 0.222
0.484SerTrp: 0.484 ± 0.063
2.857SerTyr: 2.857 ± 0.222
0.0SerXaa: 0.0 ± 0.0
Thr
2.895ThrAla: 2.895 ± 0.171
0.766ThrCys: 0.766 ± 0.09
4.628ThrAsp: 4.628 ± 0.291
3.721ThrGlu: 3.721 ± 0.183
2.389ThrPhe: 2.389 ± 0.151
3.52ThrGly: 3.52 ± 0.302
1.302ThrHis: 1.302 ± 0.122
4.74ThrIle: 4.74 ± 0.276
5.558ThrLys: 5.558 ± 0.269
4.837ThrLeu: 4.837 ± 0.233
1.198ThrMet: 1.198 ± 0.091
5.566ThrAsn: 5.566 ± 0.221
2.634ThrPro: 2.634 ± 0.189
1.942ThrGln: 1.942 ± 0.143
2.069ThrArg: 2.069 ± 0.155
4.003ThrSer: 4.003 ± 0.217
4.792ThrThr: 4.792 ± 0.318
3.095ThrVal: 3.095 ± 0.183
0.484ThrTrp: 0.484 ± 0.069
2.575ThrTyr: 2.575 ± 0.178
0.0ThrXaa: 0.0 ± 0.0
Val
2.917ValAla: 2.917 ± 0.24
0.848ValCys: 0.848 ± 0.078
3.78ValAsp: 3.78 ± 0.202
3.646ValGlu: 3.646 ± 0.215
2.403ValPhe: 2.403 ± 0.135
2.88ValGly: 2.88 ± 0.254
0.632ValHis: 0.632 ± 0.071
4.517ValIle: 4.517 ± 0.217
4.398ValLys: 4.398 ± 0.192
4.294ValLeu: 4.294 ± 0.219
1.109ValMet: 1.109 ± 0.089
3.899ValAsn: 3.899 ± 0.219
1.845ValPro: 1.845 ± 0.131
1.161ValGln: 1.161 ± 0.102
1.652ValArg: 1.652 ± 0.132
4.13ValSer: 4.13 ± 0.225
2.649ValThr: 2.649 ± 0.198
3.17ValVal: 3.17 ± 0.219
0.387ValTrp: 0.387 ± 0.061
2.426ValTyr: 2.426 ± 0.131
0.0ValXaa: 0.0 ± 0.0
Trp
0.365TrpAla: 0.365 ± 0.06
0.171TrpCys: 0.171 ± 0.034
0.35TrpAsp: 0.35 ± 0.06
0.566TrpGlu: 0.566 ± 0.066
0.394TrpPhe: 0.394 ± 0.065
0.484TrpGly: 0.484 ± 0.056
0.186TrpHis: 0.186 ± 0.033
0.424TrpIle: 0.424 ± 0.068
0.618TrpLys: 0.618 ± 0.068
0.58TrpLeu: 0.58 ± 0.064
0.32TrpMet: 0.32 ± 0.055
0.647TrpAsn: 0.647 ± 0.083
0.149TrpPro: 0.149 ± 0.036
0.156TrpGln: 0.156 ± 0.035
0.268TrpArg: 0.268 ± 0.051
0.499TrpSer: 0.499 ± 0.071
0.558TrpThr: 0.558 ± 0.078
0.603TrpVal: 0.603 ± 0.097
0.03TrpTrp: 0.03 ± 0.014
0.335TrpTyr: 0.335 ± 0.056
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.927TyrAla: 1.927 ± 0.131
0.685TyrCys: 0.685 ± 0.075
3.46TyrAsp: 3.46 ± 0.238
2.723TyrGlu: 2.723 ± 0.183
2.091TyrPhe: 2.091 ± 0.169
2.165TyrGly: 2.165 ± 0.124
0.752TyrHis: 0.752 ± 0.091
4.48TyrIle: 4.48 ± 0.199
4.658TyrLys: 4.658 ± 0.216
4.026TyrLeu: 4.026 ± 0.197
1.168TyrMet: 1.168 ± 0.113
4.859TyrAsn: 4.859 ± 0.258
1.228TyrPro: 1.228 ± 0.097
1.168TyrGln: 1.168 ± 0.118
1.332TyrArg: 1.332 ± 0.108
3.282TyrSer: 3.282 ± 0.184
3.088TyrThr: 3.088 ± 0.169
2.47TyrVal: 2.47 ± 0.16
0.387TyrTrp: 0.387 ± 0.062
2.753TyrTyr: 2.753 ± 0.167
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 433 proteins (134390 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski