Amino acid dipepetide frequency for Merremia mosaic virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.899AlaAla: 4.899 ± 1.741
0.0AlaCys: 0.0 ± 0.0
2.799AlaAsp: 2.799 ± 1.483
0.7AlaGlu: 0.7 ± 0.579
0.7AlaPhe: 0.7 ± 0.562
1.4AlaGly: 1.4 ± 1.276
1.4AlaHis: 1.4 ± 0.82
2.799AlaIle: 2.799 ± 1.724
6.298AlaLys: 6.298 ± 2.353
6.298AlaLeu: 6.298 ± 1.658
1.4AlaMet: 1.4 ± 0.987
2.099AlaAsn: 2.099 ± 0.997
2.099AlaPro: 2.099 ± 0.789
5.598AlaGln: 5.598 ± 2.388
4.199AlaArg: 4.199 ± 1.494
8.397AlaSer: 8.397 ± 1.719
3.499AlaThr: 3.499 ± 1.051
2.099AlaVal: 2.099 ± 1.074
1.4AlaTrp: 1.4 ± 0.796
0.7AlaTyr: 0.7 ± 0.763
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.7CysAsp: 0.7 ± 0.562
0.7CysGlu: 0.7 ± 0.638
0.0CysPhe: 0.0 ± 0.0
0.7CysGly: 0.7 ± 0.769
0.7CysHis: 0.7 ± 0.579
1.4CysIle: 1.4 ± 0.758
2.099CysLys: 2.099 ± 0.684
0.7CysLeu: 0.7 ± 0.692
0.7CysMet: 0.7 ± 0.562
1.4CysAsn: 1.4 ± 0.615
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
2.099CysArg: 2.099 ± 0.835
2.099CysSer: 2.099 ± 1.493
1.4CysThr: 1.4 ± 0.615
2.099CysVal: 2.099 ± 0.948
1.4CysTrp: 1.4 ± 1.384
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.4AspAla: 1.4 ± 0.758
0.7AspCys: 0.7 ± 0.769
2.099AspAsp: 2.099 ± 1.493
4.199AspGlu: 4.199 ± 1.073
2.799AspPhe: 2.799 ± 1.074
2.099AspGly: 2.099 ± 1.136
1.4AspHis: 1.4 ± 0.862
3.499AspIle: 3.499 ± 1.436
2.099AspLys: 2.099 ± 1.197
6.298AspLeu: 6.298 ± 1.35
0.7AspMet: 0.7 ± 0.692
4.199AspAsn: 4.199 ± 0.635
1.4AspPro: 1.4 ± 1.123
0.7AspGln: 0.7 ± 0.763
4.199AspArg: 4.199 ± 1.122
4.199AspSer: 4.199 ± 1.457
2.799AspThr: 2.799 ± 1.006
5.598AspVal: 5.598 ± 1.517
0.7AspTrp: 0.7 ± 0.579
0.7AspTyr: 0.7 ± 0.692
0.0AspXaa: 0.0 ± 0.0
Glu
2.099GluAla: 2.099 ± 1.237
0.7GluCys: 0.7 ± 0.562
0.0GluAsp: 0.0 ± 0.0
4.199GluGlu: 4.199 ± 2.187
0.7GluPhe: 0.7 ± 0.692
4.899GluGly: 4.899 ± 1.463
0.0GluHis: 0.0 ± 0.0
2.099GluIle: 2.099 ± 1.026
1.4GluLys: 1.4 ± 0.862
3.499GluLeu: 3.499 ± 1.125
0.7GluMet: 0.7 ± 0.579
4.199GluAsn: 4.199 ± 1.515
4.199GluPro: 4.199 ± 1.39
2.099GluGln: 2.099 ± 1.322
2.799GluArg: 2.799 ± 1.232
4.199GluSer: 4.199 ± 1.418
0.7GluThr: 0.7 ± 0.692
1.4GluVal: 1.4 ± 0.987
2.099GluTrp: 2.099 ± 1.209
2.099GluTyr: 2.099 ± 1.026
0.0GluXaa: 0.0 ± 0.0
Phe
1.4PheAla: 1.4 ± 0.902
0.7PheCys: 0.7 ± 0.638
2.099PheAsp: 2.099 ± 1.313
1.4PheGlu: 1.4 ± 0.796
2.099PhePhe: 2.099 ± 1.054
2.799PheGly: 2.799 ± 1.123
0.7PheHis: 0.7 ± 0.579
2.799PheIle: 2.799 ± 1.139
5.598PheLys: 5.598 ± 3.024
2.799PheLeu: 2.799 ± 2.315
0.0PheMet: 0.0 ± 0.0
4.899PheAsn: 4.899 ± 1.425
1.4PhePro: 1.4 ± 1.123
4.199PheGln: 4.199 ± 1.683
1.4PheArg: 1.4 ± 0.862
4.199PheSer: 4.199 ± 2.0
2.099PheThr: 2.099 ± 0.835
1.4PheVal: 1.4 ± 1.384
2.099PheTrp: 2.099 ± 1.493
2.799PheTyr: 2.799 ± 1.318
0.0PheXaa: 0.0 ± 0.0
Gly
4.899GlyAla: 4.899 ± 1.793
2.099GlyCys: 2.099 ± 0.944
2.099GlyAsp: 2.099 ± 1.054
2.799GlyGlu: 2.799 ± 1.059
0.7GlyPhe: 0.7 ± 0.769
4.199GlyGly: 4.199 ± 1.994
0.7GlyHis: 0.7 ± 0.579
2.099GlyIle: 2.099 ± 0.728
6.298GlyLys: 6.298 ± 2.962
1.4GlyLeu: 1.4 ± 0.862
1.4GlyMet: 1.4 ± 0.703
0.7GlyAsn: 0.7 ± 0.638
2.799GlyPro: 2.799 ± 1.733
3.499GlyGln: 3.499 ± 1.418
3.499GlyArg: 3.499 ± 1.488
2.099GlySer: 2.099 ± 0.835
5.598GlyThr: 5.598 ± 1.535
3.499GlyVal: 3.499 ± 2.099
0.0GlyTrp: 0.0 ± 0.0
0.7GlyTyr: 0.7 ± 0.562
0.0GlyXaa: 0.0 ± 0.0
His
0.7HisAla: 0.7 ± 0.638
1.4HisCys: 1.4 ± 0.849
3.499HisAsp: 3.499 ± 0.888
2.099HisGlu: 2.099 ± 1.459
3.499HisPhe: 3.499 ± 1.168
1.4HisGly: 1.4 ± 0.928
2.799HisHis: 2.799 ± 2.225
0.7HisIle: 0.7 ± 0.769
0.7HisLys: 0.7 ± 0.763
2.799HisLeu: 2.799 ± 1.097
0.7HisMet: 0.7 ± 0.533
3.499HisAsn: 3.499 ± 1.542
2.099HisPro: 2.099 ± 0.741
2.099HisGln: 2.099 ± 0.948
3.499HisArg: 3.499 ± 1.913
2.099HisSer: 2.099 ± 1.074
2.799HisThr: 2.799 ± 1.096
2.799HisVal: 2.799 ± 0.559
0.7HisTrp: 0.7 ± 0.579
0.7HisTyr: 0.7 ± 0.562
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
2.799IleCys: 2.799 ± 1.76
3.499IleAsp: 3.499 ± 1.627
4.199IleGlu: 4.199 ± 1.532
2.099IlePhe: 2.099 ± 1.209
3.499IleGly: 3.499 ± 2.072
5.598IleHis: 5.598 ± 1.839
3.499IleIle: 3.499 ± 1.51
5.598IleLys: 5.598 ± 1.826
2.099IleLeu: 2.099 ± 1.172
0.0IleMet: 0.0 ± 0.0
2.799IleAsn: 2.799 ± 1.284
2.799IlePro: 2.799 ± 1.019
3.499IleGln: 3.499 ± 1.969
5.598IleArg: 5.598 ± 1.841
6.298IleSer: 6.298 ± 1.298
2.799IleThr: 2.799 ± 0.927
2.799IleVal: 2.799 ± 1.08
2.099IleTrp: 2.099 ± 1.546
3.499IleTyr: 3.499 ± 1.742
0.0IleXaa: 0.0 ± 0.0
Lys
5.598LysAla: 5.598 ± 1.662
0.7LysCys: 0.7 ± 0.692
6.298LysAsp: 6.298 ± 1.819
2.099LysGlu: 2.099 ± 1.736
2.799LysPhe: 2.799 ± 1.059
4.199LysGly: 4.199 ± 1.073
2.099LysHis: 2.099 ± 1.054
4.899LysIle: 4.899 ± 0.979
0.7LysLys: 0.7 ± 0.579
4.199LysLeu: 4.199 ± 1.376
2.799LysMet: 2.799 ± 1.246
2.799LysAsn: 2.799 ± 1.096
3.499LysPro: 3.499 ± 1.119
0.7LysGln: 0.7 ± 0.562
6.298LysArg: 6.298 ± 3.695
4.899LysSer: 4.899 ± 1.744
2.099LysThr: 2.099 ± 0.835
4.199LysVal: 4.199 ± 2.959
0.0LysTrp: 0.0 ± 0.0
2.099LysTyr: 2.099 ± 1.237
0.0LysXaa: 0.0 ± 0.0
Leu
2.099LeuAla: 2.099 ± 1.313
0.7LeuCys: 0.7 ± 0.579
6.298LeuAsp: 6.298 ± 2.075
1.4LeuGlu: 1.4 ± 0.902
0.7LeuPhe: 0.7 ± 0.769
3.499LeuGly: 3.499 ± 0.975
4.899LeuHis: 4.899 ± 1.351
2.799LeuIle: 2.799 ± 1.049
6.298LeuLys: 6.298 ± 1.373
2.799LeuLeu: 2.799 ± 1.147
1.4LeuMet: 1.4 ± 0.903
5.598LeuAsn: 5.598 ± 2.09
2.099LeuPro: 2.099 ± 1.217
2.799LeuGln: 2.799 ± 1.023
3.499LeuArg: 3.499 ± 1.051
8.397LeuSer: 8.397 ± 2.146
2.099LeuThr: 2.099 ± 0.737
4.199LeuVal: 4.199 ± 1.077
0.0LeuTrp: 0.0 ± 0.0
3.499LeuTyr: 3.499 ± 1.361
0.0LeuXaa: 0.0 ± 0.0
Met
2.799MetAla: 2.799 ± 1.516
0.0MetCys: 0.0 ± 0.0
3.499MetAsp: 3.499 ± 1.174
0.0MetGlu: 0.0 ± 0.0
0.7MetPhe: 0.7 ± 0.638
0.7MetGly: 0.7 ± 0.638
0.7MetHis: 0.7 ± 0.638
0.7MetIle: 0.7 ± 0.562
1.4MetLys: 1.4 ± 0.849
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
1.4MetAsn: 1.4 ± 0.987
0.7MetPro: 0.7 ± 0.579
1.4MetGln: 1.4 ± 0.831
0.0MetArg: 0.0 ± 0.0
3.499MetSer: 3.499 ± 2.789
1.4MetThr: 1.4 ± 0.862
1.4MetVal: 1.4 ± 0.711
0.7MetTrp: 0.7 ± 0.579
2.799MetTyr: 2.799 ± 1.223
0.0MetXaa: 0.0 ± 0.0
Asn
6.298AsnAla: 6.298 ± 1.782
4.199AsnCys: 4.199 ± 0.91
2.799AsnAsp: 2.799 ± 1.074
2.799AsnGlu: 2.799 ± 1.436
1.4AsnPhe: 1.4 ± 0.903
2.799AsnGly: 2.799 ± 1.204
2.799AsnHis: 2.799 ± 2.066
5.598AsnIle: 5.598 ± 1.505
1.4AsnLys: 1.4 ± 0.742
2.799AsnLeu: 2.799 ± 1.693
1.4AsnMet: 1.4 ± 1.099
2.099AsnAsn: 2.099 ± 0.894
4.199AsnPro: 4.199 ± 0.662
1.4AsnGln: 1.4 ± 0.928
3.499AsnArg: 3.499 ± 0.553
3.499AsnSer: 3.499 ± 0.527
0.7AsnThr: 0.7 ± 0.769
2.099AsnVal: 2.099 ± 1.197
0.0AsnTrp: 0.0 ± 0.0
6.298AsnTyr: 6.298 ± 1.59
0.0AsnXaa: 0.0 ± 0.0
Pro
1.4ProAla: 1.4 ± 1.123
0.7ProCys: 0.7 ± 0.638
1.4ProAsp: 1.4 ± 0.796
2.799ProGlu: 2.799 ± 1.424
2.099ProPhe: 2.099 ± 0.737
2.099ProGly: 2.099 ± 1.026
1.4ProHis: 1.4 ± 0.742
5.598ProIle: 5.598 ± 2.21
2.799ProLys: 2.799 ± 1.147
2.099ProLeu: 2.099 ± 1.094
1.4ProMet: 1.4 ± 1.276
4.199ProAsn: 4.199 ± 1.625
2.099ProPro: 2.099 ± 0.741
0.7ProGln: 0.7 ± 0.579
2.099ProArg: 2.099 ± 1.322
6.998ProSer: 6.998 ± 1.914
1.4ProThr: 1.4 ± 0.742
2.099ProVal: 2.099 ± 1.237
2.099ProTrp: 2.099 ± 0.728
2.799ProTyr: 2.799 ± 0.927
0.0ProXaa: 0.0 ± 0.0
Gln
2.799GlnAla: 2.799 ± 1.545
0.0GlnCys: 0.0 ± 0.0
0.7GlnAsp: 0.7 ± 0.769
2.099GlnGlu: 2.099 ± 1.237
2.799GlnPhe: 2.799 ± 1.006
0.7GlnGly: 0.7 ± 0.579
2.099GlnHis: 2.099 ± 1.209
4.199GlnIle: 4.199 ± 2.395
1.4GlnLys: 1.4 ± 1.157
5.598GlnLeu: 5.598 ± 2.524
0.0GlnMet: 0.0 ± 0.0
1.4GlnAsn: 1.4 ± 1.538
2.099GlnPro: 2.099 ± 0.741
1.4GlnGln: 1.4 ± 0.615
2.099GlnArg: 2.099 ± 0.789
4.199GlnSer: 4.199 ± 1.467
2.099GlnThr: 2.099 ± 0.737
3.499GlnVal: 3.499 ± 1.174
0.0GlnTrp: 0.0 ± 0.0
0.7GlnTyr: 0.7 ± 0.638
0.0GlnXaa: 0.0 ± 0.0
Arg
4.899ArgAla: 4.899 ± 0.953
0.7ArgCys: 0.7 ± 0.562
2.799ArgAsp: 2.799 ± 1.881
0.7ArgGlu: 0.7 ± 0.579
8.397ArgPhe: 8.397 ± 2.695
4.899ArgGly: 4.899 ± 2.409
2.099ArgHis: 2.099 ± 0.91
4.199ArgIle: 4.199 ± 0.98
4.199ArgLys: 4.199 ± 0.98
3.499ArgLeu: 3.499 ± 1.176
0.7ArgMet: 0.7 ± 0.562
1.4ArgAsn: 1.4 ± 1.001
2.799ArgPro: 2.799 ± 1.096
2.099ArgGln: 2.099 ± 1.28
4.899ArgArg: 4.899 ± 3.225
8.397ArgSer: 8.397 ± 1.447
4.199ArgThr: 4.199 ± 0.98
4.199ArgVal: 4.199 ± 1.66
0.7ArgTrp: 0.7 ± 0.562
1.4ArgTyr: 1.4 ± 1.384
0.0ArgXaa: 0.0 ± 0.0
Ser
6.298SerAla: 6.298 ± 2.501
1.4SerCys: 1.4 ± 0.862
2.099SerAsp: 2.099 ± 0.684
2.799SerGlu: 2.799 ± 1.019
5.598SerPhe: 5.598 ± 1.378
2.799SerGly: 2.799 ± 1.056
3.499SerHis: 3.499 ± 1.657
6.998SerIle: 6.998 ± 2.132
4.899SerLys: 4.899 ± 2.845
6.998SerLeu: 6.998 ± 1.855
2.099SerMet: 2.099 ± 1.28
7.698SerAsn: 7.698 ± 1.513
4.899SerPro: 4.899 ± 1.97
1.4SerGln: 1.4 ± 0.742
4.899SerArg: 4.899 ± 1.31
10.497SerSer: 10.497 ± 4.573
6.998SerThr: 6.998 ± 2.127
4.199SerVal: 4.199 ± 1.323
1.4SerTrp: 1.4 ± 1.123
2.799SerTyr: 2.799 ± 1.049
0.0SerXaa: 0.0 ± 0.0
Thr
3.499ThrAla: 3.499 ± 0.553
0.0ThrCys: 0.0 ± 0.0
3.499ThrAsp: 3.499 ± 1.845
2.099ThrGlu: 2.099 ± 0.789
2.799ThrPhe: 2.799 ± 2.115
2.099ThrGly: 2.099 ± 0.894
4.899ThrHis: 4.899 ± 2.34
3.499ThrIle: 3.499 ± 0.966
2.099ThrLys: 2.099 ± 0.684
3.499ThrLeu: 3.499 ± 1.912
2.099ThrMet: 2.099 ± 0.741
2.099ThrAsn: 2.099 ± 1.237
3.499ThrPro: 3.499 ± 0.527
1.4ThrGln: 1.4 ± 0.928
4.199ThrArg: 4.199 ± 1.173
1.4ThrSer: 1.4 ± 0.902
4.199ThrThr: 4.199 ± 2.963
3.499ThrVal: 3.499 ± 1.176
0.0ThrTrp: 0.0 ± 0.0
2.099ThrTyr: 2.099 ± 1.197
0.0ThrXaa: 0.0 ± 0.0
Val
1.4ValAla: 1.4 ± 0.742
0.7ValCys: 0.7 ± 0.562
2.799ValAsp: 2.799 ± 1.724
4.899ValGlu: 4.899 ± 1.857
3.499ValPhe: 3.499 ± 1.93
3.499ValGly: 3.499 ± 1.383
2.099ValHis: 2.099 ± 0.969
4.199ValIle: 4.199 ± 1.099
4.899ValLys: 4.899 ± 1.509
2.799ValLeu: 2.799 ± 1.641
2.799ValMet: 2.799 ± 1.422
3.499ValAsn: 3.499 ± 1.184
4.199ValPro: 4.199 ± 0.65
2.799ValGln: 2.799 ± 1.152
2.099ValArg: 2.099 ± 0.948
3.499ValSer: 3.499 ± 1.119
1.4ValThr: 1.4 ± 1.276
2.799ValVal: 2.799 ± 1.341
0.0ValTrp: 0.0 ± 0.0
4.199ValTyr: 4.199 ± 1.667
0.0ValXaa: 0.0 ± 0.0
Trp
2.799TrpAla: 2.799 ± 1.006
0.0TrpCys: 0.0 ± 0.0
0.7TrpAsp: 0.7 ± 0.769
1.4TrpGlu: 1.4 ± 0.902
0.0TrpPhe: 0.0 ± 0.0
0.7TrpGly: 0.7 ± 0.579
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
2.099TrpLys: 2.099 ± 0.728
0.7TrpLeu: 0.7 ± 0.638
1.4TrpMet: 1.4 ± 0.711
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.7TrpGln: 0.7 ± 0.579
1.4TrpArg: 1.4 ± 1.001
0.0TrpSer: 0.0 ± 0.0
2.099TrpThr: 2.099 ± 0.795
1.4TrpVal: 1.4 ± 0.796
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.499TyrAla: 3.499 ± 1.658
0.7TyrCys: 0.7 ± 0.692
2.099TyrAsp: 2.099 ± 1.161
0.7TyrGlu: 0.7 ± 0.638
3.499TyrPhe: 3.499 ± 0.995
2.099TyrGly: 2.099 ± 0.728
0.7TyrHis: 0.7 ± 0.692
3.499TyrIle: 3.499 ± 1.027
0.7TyrLys: 0.7 ± 0.579
4.199TyrLeu: 4.199 ± 2.396
1.4TyrMet: 1.4 ± 0.836
2.799TyrAsn: 2.799 ± 1.204
1.4TyrPro: 1.4 ± 0.742
1.4TyrGln: 1.4 ± 0.615
4.899TyrArg: 4.899 ± 1.915
1.4TyrSer: 1.4 ± 0.742
2.099TyrThr: 2.099 ± 1.623
2.799TyrVal: 2.799 ± 1.175
0.0TyrTrp: 0.0 ± 0.0
2.099TyrTyr: 2.099 ± 1.459
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1430 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski