Amino acid dipepetide frequency for Ceratobasidium endornavirus C

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.404AlaAla: 7.404 ± 1.606
1.307AlaCys: 1.307 ± 0.021
3.484AlaAsp: 3.484 ± 0.699
4.936AlaGlu: 4.936 ± 1.717
2.178AlaPhe: 2.178 ± 0.396
3.775AlaGly: 3.775 ± 0.455
1.742AlaHis: 1.742 ± 0.188
5.807AlaIle: 5.807 ± 1.164
5.517AlaLys: 5.517 ± 1.025
7.549AlaLeu: 7.549 ± 0.264
1.307AlaMet: 1.307 ± 0.021
4.355AlaAsn: 4.355 ± 0.792
2.323AlaPro: 2.323 ± 0.827
4.065AlaGln: 4.065 ± 0.007
3.63AlaArg: 3.63 ± 1.494
5.081AlaSer: 5.081 ± 0.494
7.114AlaThr: 7.114 ± 0.174
4.936AlaVal: 4.936 ± 0.424
2.178AlaTrp: 2.178 ± 0.573
2.758AlaTyr: 2.758 ± 1.264
0.0AlaXaa: 0.0 ± 0.0
Cys
1.161CysAla: 1.161 ± 0.413
0.581CysCys: 0.581 ± 0.045
0.581CysAsp: 0.581 ± 0.045
0.871CysGlu: 0.871 ± 0.094
0.726CysPhe: 0.726 ± 0.347
1.742CysGly: 1.742 ± 0.135
0.29CysHis: 0.29 ± 0.184
1.016CysIle: 1.016 ± 0.806
0.871CysLys: 0.871 ± 0.094
1.161CysLeu: 1.161 ± 0.09
0.871CysMet: 0.871 ± 0.229
0.871CysAsn: 0.871 ± 0.094
1.016CysPro: 1.016 ± 0.16
0.145CysGln: 0.145 ± 0.069
1.452CysArg: 1.452 ± 0.049
1.742CysSer: 1.742 ± 0.511
1.452CysThr: 1.452 ± 0.049
0.29CysVal: 0.29 ± 0.139
0.581CysTrp: 0.581 ± 0.368
0.581CysTyr: 0.581 ± 0.045
0.0CysXaa: 0.0 ± 0.0
Asp
3.194AspAla: 3.194 ± 0.087
1.307AspCys: 1.307 ± 0.344
2.904AspAsp: 2.904 ± 0.744
3.775AspGlu: 3.775 ± 0.191
2.323AspPhe: 2.323 ± 0.466
3.63AspGly: 3.63 ± 0.445
2.323AspHis: 2.323 ± 0.143
2.178AspIle: 2.178 ± 0.396
3.484AspLys: 3.484 ± 0.375
6.678AspLeu: 6.678 ± 0.612
1.742AspMet: 1.742 ± 0.188
1.887AspAsn: 1.887 ± 0.903
2.323AspPro: 2.323 ± 0.789
2.323AspGln: 2.323 ± 0.789
3.049AspArg: 3.049 ± 0.479
2.468AspSer: 2.468 ± 0.858
3.194AspThr: 3.194 ± 0.087
3.63AspVal: 3.63 ± 0.122
0.871AspTrp: 0.871 ± 0.094
1.016AspTyr: 1.016 ± 0.16
0.0AspXaa: 0.0 ± 0.0
Glu
5.517GluAla: 5.517 ± 0.056
0.581GluCys: 0.581 ± 0.278
3.775GluAsp: 3.775 ± 0.514
2.468GluGlu: 2.468 ± 0.535
2.323GluPhe: 2.323 ± 0.143
3.63GluGly: 3.63 ± 0.445
1.161GluHis: 1.161 ± 0.09
3.339GluIle: 3.339 ± 0.017
2.758GluLys: 2.758 ± 0.351
4.791GluLeu: 4.791 ± 0.032
3.049GluMet: 3.049 ± 0.479
3.484GluAsn: 3.484 ± 0.052
3.775GluPro: 3.775 ± 0.455
2.758GluGln: 2.758 ± 0.028
1.887GluArg: 1.887 ± 0.066
2.613GluSer: 2.613 ± 0.605
3.194GluThr: 3.194 ± 0.56
2.613GluVal: 2.613 ± 0.365
1.452GluTrp: 1.452 ± 0.597
1.742GluTyr: 1.742 ± 0.135
0.0GluXaa: 0.0 ± 0.0
Phe
2.323PheAla: 2.323 ± 0.789
0.581PheCys: 0.581 ± 0.045
2.178PheAsp: 2.178 ± 0.396
2.323PheGlu: 2.323 ± 0.143
0.436PhePhe: 0.436 ± 0.115
2.613PheGly: 2.613 ± 0.365
0.726PheHis: 0.726 ± 0.299
0.871PheIle: 0.871 ± 0.552
2.468PheLys: 2.468 ± 0.212
2.033PheLeu: 2.033 ± 1.289
0.726PheMet: 0.726 ± 0.347
2.758PheAsn: 2.758 ± 0.028
0.436PhePro: 0.436 ± 0.115
0.726PheGln: 0.726 ± 0.347
1.307PheArg: 1.307 ± 0.344
1.887PheSer: 1.887 ± 0.257
2.033PheThr: 2.033 ± 0.004
2.033PheVal: 2.033 ± 0.643
0.145PheTrp: 0.145 ± 0.254
0.726PheTyr: 0.726 ± 0.945
0.0PheXaa: 0.0 ± 0.0
Gly
4.21GlyAla: 4.21 ± 0.569
0.871GlyCys: 0.871 ± 0.229
3.63GlyAsp: 3.63 ± 0.445
4.21GlyGlu: 4.21 ± 0.4
2.178GlyPhe: 2.178 ± 0.073
5.226GlyGly: 5.226 ± 2.022
2.178GlyHis: 2.178 ± 0.573
3.049GlyIle: 3.049 ± 0.802
3.339GlyLys: 3.339 ± 0.952
5.662GlyLeu: 5.662 ± 1.813
2.904GlyMet: 2.904 ± 0.421
3.339GlyAsn: 3.339 ± 0.306
2.904GlyPro: 2.904 ± 0.421
3.194GlyGln: 3.194 ± 0.41
2.178GlyArg: 2.178 ± 0.573
5.662GlySer: 5.662 ± 0.125
3.484GlyThr: 3.484 ± 0.052
4.646GlyVal: 4.646 ± 0.285
1.887GlyTrp: 1.887 ± 0.066
1.887GlyTyr: 1.887 ± 1.035
0.0GlyXaa: 0.0 ± 0.0
His
2.033HisAla: 2.033 ± 0.319
0.29HisCys: 0.29 ± 0.139
1.452HisAsp: 1.452 ± 0.921
1.016HisGlu: 1.016 ± 0.16
1.597HisPhe: 1.597 ± 0.205
2.033HisGly: 2.033 ± 0.643
1.161HisHis: 1.161 ± 0.233
1.452HisIle: 1.452 ± 0.049
1.161HisLys: 1.161 ± 0.233
1.887HisLeu: 1.887 ± 0.257
0.871HisMet: 0.871 ± 0.552
1.887HisAsn: 1.887 ± 0.066
1.307HisPro: 1.307 ± 0.021
0.436HisGln: 0.436 ± 0.208
2.178HisArg: 2.178 ± 0.25
2.033HisSer: 2.033 ± 0.327
1.597HisThr: 1.597 ± 0.205
1.742HisVal: 1.742 ± 0.458
1.452HisTrp: 1.452 ± 0.274
1.161HisTyr: 1.161 ± 0.233
0.0HisXaa: 0.0 ± 0.0
Ile
3.049IleAla: 3.049 ± 0.479
0.726IleCys: 0.726 ± 0.945
3.63IleAsp: 3.63 ± 0.122
3.63IleGlu: 3.63 ± 0.524
1.016IlePhe: 1.016 ± 0.483
4.065IleGly: 4.065 ± 0.33
0.871IleHis: 0.871 ± 0.094
2.904IleIle: 2.904 ± 0.097
2.178IleLys: 2.178 ± 0.719
3.339IleLeu: 3.339 ± 1.275
0.871IleMet: 0.871 ± 0.229
2.613IleAsn: 2.613 ± 0.042
3.049IlePro: 3.049 ± 1.448
1.161IleGln: 1.161 ± 0.09
2.178IleArg: 2.178 ± 0.573
3.92IleSer: 3.92 ± 0.385
5.081IleThr: 5.081 ± 1.14
2.613IleVal: 2.613 ± 0.282
0.726IleTrp: 0.726 ± 0.347
1.742IleTyr: 1.742 ± 0.188
0.0IleXaa: 0.0 ± 0.0
Lys
5.517LysAla: 5.517 ± 1.671
1.161LysCys: 1.161 ± 0.233
3.63LysAsp: 3.63 ± 0.768
2.758LysGlu: 2.758 ± 0.351
1.887LysPhe: 1.887 ± 0.712
4.065LysGly: 4.065 ± 0.653
2.178LysHis: 2.178 ± 0.25
2.613LysIle: 2.613 ± 0.605
2.613LysLys: 2.613 ± 0.042
4.355LysLeu: 4.355 ± 0.146
2.613LysMet: 2.613 ± 0.252
2.033LysAsn: 2.033 ± 0.65
3.194LysPro: 3.194 ± 0.733
2.613LysGln: 2.613 ± 0.282
2.758LysArg: 2.758 ± 0.997
2.323LysSer: 2.323 ± 0.504
3.775LysThr: 3.775 ± 0.838
3.775LysVal: 3.775 ± 0.838
1.307LysTrp: 1.307 ± 0.667
2.178LysTyr: 2.178 ± 0.719
0.0LysXaa: 0.0 ± 0.0
Leu
9.146LeuAla: 9.146 ± 0.468
2.033LeuCys: 2.033 ± 0.319
4.355LeuAsp: 4.355 ± 0.146
5.081LeuGlu: 5.081 ± 0.494
1.887LeuPhe: 1.887 ± 0.712
4.21LeuGly: 4.21 ± 0.4
2.468LeuHis: 2.468 ± 0.535
2.033LeuIle: 2.033 ± 0.004
4.065LeuLys: 4.065 ± 0.33
8.275LeuLeu: 8.275 ± 1.699
2.178LeuMet: 2.178 ± 0.38
5.517LeuAsn: 5.517 ± 0.379
5.226LeuPro: 5.226 ± 0.563
4.065LeuGln: 4.065 ± 1.931
4.791LeuArg: 4.791 ± 1.001
5.372LeuSer: 5.372 ± 0.014
5.517LeuThr: 5.517 ± 1.025
6.098LeuVal: 6.098 ± 0.657
1.016LeuTrp: 1.016 ± 0.16
3.049LeuTyr: 3.049 ± 1.125
0.0LeuXaa: 0.0 ± 0.0
Met
2.758MetAla: 2.758 ± 0.351
0.581MetCys: 0.581 ± 0.045
2.613MetAsp: 2.613 ± 0.282
1.887MetGlu: 1.887 ± 0.257
1.161MetPhe: 1.161 ± 0.556
1.742MetGly: 1.742 ± 0.188
1.742MetHis: 1.742 ± 0.135
0.581MetIle: 0.581 ± 0.368
1.307MetLys: 1.307 ± 0.344
3.049MetLeu: 3.049 ± 0.167
1.016MetMet: 1.016 ± 0.486
1.887MetAsn: 1.887 ± 0.389
2.468MetPro: 2.468 ± 0.111
1.016MetGln: 1.016 ± 0.486
1.887MetArg: 1.887 ± 0.066
1.452MetSer: 1.452 ± 0.597
1.597MetThr: 1.597 ± 0.205
1.597MetVal: 1.597 ± 0.118
0.145MetTrp: 0.145 ± 0.069
0.871MetTyr: 0.871 ± 0.229
0.0MetXaa: 0.0 ± 0.0
Asn
5.226AsnAla: 5.226 ± 0.563
1.016AsnCys: 1.016 ± 0.486
1.597AsnAsp: 1.597 ± 0.118
3.049AsnGlu: 3.049 ± 0.49
1.597AsnPhe: 1.597 ± 0.205
4.21AsnGly: 4.21 ± 0.246
1.016AsnHis: 1.016 ± 0.486
2.323AsnIle: 2.323 ± 0.143
3.92AsnLys: 3.92 ± 0.584
5.517AsnLeu: 5.517 ± 0.379
1.452AsnMet: 1.452 ± 0.274
2.904AsnAsn: 2.904 ± 0.097
2.323AsnPro: 2.323 ± 0.143
1.307AsnGln: 1.307 ± 0.021
2.468AsnArg: 2.468 ± 0.434
3.775AsnSer: 3.775 ± 0.778
3.194AsnThr: 3.194 ± 0.087
3.339AsnVal: 3.339 ± 0.306
1.161AsnTrp: 1.161 ± 0.09
2.178AsnTyr: 2.178 ± 0.396
0.0AsnXaa: 0.0 ± 0.0
Pro
4.791ProAla: 4.791 ± 1.584
0.581ProCys: 0.581 ± 0.045
2.033ProAsp: 2.033 ± 0.65
2.758ProGlu: 2.758 ± 0.028
1.161ProPhe: 1.161 ± 0.413
3.339ProGly: 3.339 ± 0.34
1.307ProHis: 1.307 ± 0.302
2.468ProIle: 2.468 ± 0.434
2.758ProLys: 2.758 ± 0.028
3.484ProLeu: 3.484 ± 1.022
1.597ProMet: 1.597 ± 0.441
2.758ProAsn: 2.758 ± 0.941
1.742ProPro: 1.742 ± 1.428
1.597ProGln: 1.597 ± 0.118
2.323ProArg: 2.323 ± 0.18
3.484ProSer: 3.484 ± 1.24
3.339ProThr: 3.339 ± 0.34
3.049ProVal: 3.049 ± 0.167
0.29ProTrp: 0.29 ± 0.184
0.581ProTyr: 0.581 ± 0.278
0.0ProXaa: 0.0 ± 0.0
Gln
3.194GlnAla: 3.194 ± 0.41
0.29GlnCys: 0.29 ± 0.139
1.452GlnAsp: 1.452 ± 0.274
1.742GlnGlu: 1.742 ± 0.135
0.871GlnPhe: 0.871 ± 0.094
2.468GlnGly: 2.468 ± 0.111
1.307GlnHis: 1.307 ± 0.344
2.613GlnIle: 2.613 ± 0.042
2.613GlnLys: 2.613 ± 0.042
4.355GlnLeu: 4.355 ± 0.177
1.161GlnMet: 1.161 ± 0.556
1.016GlnAsn: 1.016 ± 0.16
1.742GlnPro: 1.742 ± 0.458
1.887GlnGln: 1.887 ± 0.066
2.033GlnArg: 2.033 ± 0.327
3.049GlnSer: 3.049 ± 0.156
3.63GlnThr: 3.63 ± 0.122
2.468GlnVal: 2.468 ± 0.212
0.726GlnTrp: 0.726 ± 0.024
1.597GlnTyr: 1.597 ± 0.118
0.0GlnXaa: 0.0 ± 0.0
Arg
3.484ArgAla: 3.484 ± 0.699
1.161ArgCys: 1.161 ± 0.09
2.904ArgAsp: 2.904 ± 0.549
2.468ArgGlu: 2.468 ± 0.111
1.016ArgPhe: 1.016 ± 0.16
3.484ArgGly: 3.484 ± 0.271
1.016ArgHis: 1.016 ± 0.163
2.323ArgIle: 2.323 ± 0.504
2.904ArgLys: 2.904 ± 1.067
4.936ArgLeu: 4.936 ± 0.222
1.597ArgMet: 1.597 ± 0.118
2.468ArgAsn: 2.468 ± 0.111
1.887ArgPro: 1.887 ± 0.066
2.178ArgGln: 2.178 ± 0.25
3.194ArgArg: 3.194 ± 0.236
3.049ArgSer: 3.049 ± 0.167
2.468ArgThr: 2.468 ± 0.212
4.355ArgVal: 4.355 ± 0.823
1.307ArgTrp: 1.307 ± 0.302
1.742ArgTyr: 1.742 ± 0.458
0.0ArgXaa: 0.0 ± 0.0
Ser
4.936SerAla: 4.936 ± 1.717
1.307SerCys: 1.307 ± 0.302
3.339SerAsp: 3.339 ± 1.275
2.904SerGlu: 2.904 ± 0.097
1.887SerPhe: 1.887 ± 0.712
4.936SerGly: 4.936 ± 1.191
1.742SerHis: 1.742 ± 0.782
4.355SerIle: 4.355 ± 0.469
4.21SerLys: 4.21 ± 0.569
5.081SerLeu: 5.081 ± 0.476
2.178SerMet: 2.178 ± 0.073
4.646SerAsn: 4.646 ± 0.038
2.468SerPro: 2.468 ± 0.535
2.904SerGln: 2.904 ± 0.549
3.339SerArg: 3.339 ± 0.629
3.339SerSer: 3.339 ± 0.017
4.791SerThr: 4.791 ± 1.261
3.339SerVal: 3.339 ± 0.629
2.033SerTrp: 2.033 ± 0.643
1.742SerTyr: 1.742 ± 0.458
0.0SerXaa: 0.0 ± 0.0
Thr
5.517ThrAla: 5.517 ± 0.056
1.597ThrCys: 1.597 ± 0.118
4.065ThrAsp: 4.065 ± 0.976
3.92ThrGlu: 3.92 ± 0.708
1.307ThrPhe: 1.307 ± 0.667
5.081ThrGly: 5.081 ± 0.153
1.307ThrHis: 1.307 ± 0.021
3.63ThrIle: 3.63 ± 0.445
5.226ThrLys: 5.226 ± 0.886
4.646ThrLeu: 4.646 ± 0.038
1.597ThrMet: 1.597 ± 0.764
3.775ThrAsn: 3.775 ± 0.514
3.049ThrPro: 3.049 ± 0.156
2.904ThrGln: 2.904 ± 0.744
3.63ThrArg: 3.63 ± 0.445
5.081ThrSer: 5.081 ± 0.171
4.646ThrThr: 4.646 ± 1.007
4.791ThrVal: 4.791 ± 0.678
1.307ThrTrp: 1.307 ± 0.021
2.613ThrTyr: 2.613 ± 0.365
0.0ThrXaa: 0.0 ± 0.0
Val
4.355ValAla: 4.355 ± 0.792
1.161ValCys: 1.161 ± 0.413
3.049ValAsp: 3.049 ± 0.167
3.339ValGlu: 3.339 ± 0.34
2.178ValPhe: 2.178 ± 0.073
3.049ValGly: 3.049 ± 0.167
2.468ValHis: 2.468 ± 0.434
3.775ValIle: 3.775 ± 0.132
3.339ValLys: 3.339 ± 0.306
6.098ValLeu: 6.098 ± 0.98
1.597ValMet: 1.597 ± 0.205
2.613ValAsn: 2.613 ± 0.042
2.613ValPro: 2.613 ± 0.042
1.597ValGln: 1.597 ± 0.441
3.63ValArg: 3.63 ± 0.524
4.646ValSer: 4.646 ± 0.038
5.952ValThr: 5.952 ± 1.557
4.355ValVal: 4.355 ± 0.177
1.307ValTrp: 1.307 ± 0.667
1.887ValTyr: 1.887 ± 0.066
0.0ValXaa: 0.0 ± 0.0
Trp
1.597TrpAla: 1.597 ± 1.174
0.871TrpCys: 0.871 ± 0.229
1.307TrpAsp: 1.307 ± 0.021
1.452TrpGlu: 1.452 ± 0.597
0.581TrpPhe: 0.581 ± 0.045
0.871TrpGly: 0.871 ± 0.229
0.436TrpHis: 0.436 ± 0.115
1.161TrpIle: 1.161 ± 0.413
1.597TrpLys: 1.597 ± 0.205
0.871TrpLeu: 0.871 ± 0.094
1.016TrpMet: 1.016 ± 0.163
1.161TrpAsn: 1.161 ± 0.556
0.726TrpPro: 0.726 ± 0.622
1.597TrpGln: 1.597 ± 0.528
0.726TrpArg: 0.726 ± 0.347
1.597TrpSer: 1.597 ± 0.205
1.016TrpThr: 1.016 ± 0.16
1.597TrpVal: 1.597 ± 0.528
0.581TrpTrp: 0.581 ± 0.045
0.29TrpTyr: 0.29 ± 0.139
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.033TyrAla: 2.033 ± 0.973
0.0TyrCys: 0.0 ± 0.0
2.323TyrAsp: 2.323 ± 0.466
2.323TyrGlu: 2.323 ± 0.827
1.016TyrPhe: 1.016 ± 0.16
2.468TyrGly: 2.468 ± 1.08
1.307TyrHis: 1.307 ± 1.313
0.871TyrIle: 0.871 ± 0.094
1.016TyrLys: 1.016 ± 0.163
2.758TyrLeu: 2.758 ± 0.295
0.871TyrMet: 0.871 ± 0.875
1.597TyrAsn: 1.597 ± 0.528
0.871TyrPro: 0.871 ± 0.094
1.742TyrGln: 1.742 ± 0.458
1.307TyrArg: 1.307 ± 0.302
2.904TyrSer: 2.904 ± 0.549
2.613TyrThr: 2.613 ± 0.282
1.742TyrVal: 1.742 ± 0.458
0.581TyrTrp: 0.581 ± 0.045
1.452TyrTyr: 1.452 ± 0.274
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (6889 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski