Mesocestoides corti
Average proteome isoelectric point is 6.84
Get precalculated fractions of proteins
Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
All
Note: above files contain also dissociation constants (pKa)
Virtual 2D-PAGE plot for 10572 proteins (isoelectric point calculated using IPC2_protein)
Get csv file with sequences according to given criteria:
* You can choose from 21 different methods for calculating isoelectric point
Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>tr|A0A0R3UD67|A0A0R3UD67_9CEST Uncharacterized protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS4866 PE=4 SV=1
MM1 pKa = 7.73 KK2 pKa = 8.09 MTTLTTTANLPDD14 pKa = 3.84 YY15 pKa = 11.04 QFATDD20 pKa = 5.42 DD21 pKa = 3.78 YY22 pKa = 8.97 TASIPAYY29 pKa = 8.88 ISPITTTPPSTTNTASDD46 pKa = 4.12 DD47 pKa = 3.68 QSHH50 pKa = 6.61 TDD52 pKa = 2.78 NHH54 pKa = 6.04 TASNPADD61 pKa = 4.01 LSPTKK66 pKa = 10.04 ATAPSTAIASSDD78 pKa = 3.5 NQSYY82 pKa = 9.74 TDD84 pKa = 4.96 DD85 pKa = 3.86 YY86 pKa = 11.84 ANSNLADD93 pKa = 3.72 ISPTTTVPLSTTNTASNDD111 pKa = 3.42 MPNTDD116 pKa = 4.05 GYY118 pKa = 11.51 AALILTDD125 pKa = 3.91 ISSMTTTPPSTTNTSSDD142 pKa = 3.48 GLTLIDD148 pKa = 3.86 DD149 pKa = 4.13 HH150 pKa = 6.77 TNPVHH155 pKa = 6.6 TDD157 pKa = 2.86 TFRR160 pKa = 11.84 ITRR163 pKa = 11.84 TTTLTTSTYY172 pKa = 10.84 SQDD175 pKa = 3.21 QTSSINSTAA184 pKa = 3.09
Molecular weight: 19.38 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 3.714
IPC2_protein 3.719
IPC_protein 3.745
Toseland 3.49
ProMoST 3.961
Dawson 3.783
Bjellqvist 3.935
Wikipedia 3.795
Rodwell 3.567
Grimsley 3.401
Solomon 3.757
Lehninger 3.719
Nozaki 3.897
DTASelect 4.266
Thurlkill 3.579
EMBOSS 3.795
Sillero 3.872
Patrickios 0.655
IPC_peptide 3.745
IPC2_peptide 3.846
IPC2.peptide.svr19 3.769
Protein with the highest isoelectric point:
>tr|A0A3P6HTI6|A0A3P6HTI6_9CEST Uncharacterized protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS10553 PE=4 SV=1
MM1 pKa = 7.22 HH2 pKa = 7.27 LWMRR6 pKa = 11.84 NVMQMRR12 pKa = 11.84 GRR14 pKa = 11.84 RR15 pKa = 11.84 KK16 pKa = 8.75 RR17 pKa = 11.84 RR18 pKa = 11.84 RR19 pKa = 11.84 RR20 pKa = 11.84 RR21 pKa = 11.84 KK22 pKa = 8.36 RR23 pKa = 11.84 KK24 pKa = 7.59 MMKK27 pKa = 9.6 RR28 pKa = 11.84 SLMRR32 pKa = 11.84 MRR34 pKa = 11.84 RR35 pKa = 11.84 PSRR38 pKa = 3.37
Molecular weight: 5.14 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 9.523
IPC2_protein 11.389
IPC_protein 12.983
Toseland 13.144
ProMoST 13.656
Dawson 13.144
Bjellqvist 13.144
Wikipedia 13.627
Rodwell 12.749
Grimsley 13.188
Solomon 13.642
Lehninger 13.554
Nozaki 13.144
DTASelect 13.144
Thurlkill 13.144
EMBOSS 13.642
Sillero 13.144
Patrickios 12.486
IPC_peptide 13.656
IPC2_peptide 12.632
IPC2.peptide.svr19 9.289
Peptides (in silico digests for buttom-up proteomics)
Below you can find
in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.
Try ESI
ChTry ESI
ArgC ESI
LysN ESI
TryLysC ESI
Try MALDI
ChTry MALDI
ArgC MALDI
LysN MALDI
TryLysC MALDI
Try LTQ
ChTry LTQ
ArgC LTQ
LysN LTQ
TryLysC LTQ
Try MSlow
ChTry MSlow
ArgC MSlow
LysN MSlow
TryLysC MSlow
Try MShigh
ChTry MShigh
ArgC MShigh
LysN MShigh
TryLysC MShigh
General Statistics
Number of major isoforms
Number of additional isoforms
Number of all proteins
Number of amino acids
Min. Seq. Length
Max. Seq. Length
Avg. Seq. Length
Avg. Mol. Weight
10572
0
10572
4885022
30
6604
462.1
51.3
Amino acid frequency
Ala
Cys
Asp
Glu
Phe
Gly
His
Ile
Lys
Leu
7.677 ± 0.025
2.179 ± 0.015
5.213 ± 0.019
5.961 ± 0.028
3.976 ± 0.018
5.818 ± 0.029
2.545 ± 0.01
4.625 ± 0.02
4.645 ± 0.022
9.759 ± 0.027
Met
Asn
Gln
Pro
Arg
Ser
Thr
Val
Trp
Tyr
1.998 ± 0.01
3.891 ± 0.013
6.135 ± 0.031
4.046 ± 0.018
6.324 ± 0.019
9.094 ± 0.031
5.872 ± 0.018
6.582 ± 0.02
1.106 ± 0.008
2.552 ± 0.012
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level
Most of the basic statistics you can see at this page can be downloaded from this CSV file
For dipeptide frequency statistics click here