Amino acid dipepetide frequency for Tomato yellow leaf curl virus - Mild

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.45AlaAla: 5.45 ± 2.474
0.908AlaCys: 0.908 ± 0.765
0.0AlaAsp: 0.0 ± 0.0
1.817AlaGlu: 1.817 ± 1.598
0.0AlaPhe: 0.0 ± 0.0
0.908AlaGly: 0.908 ± 0.999
1.817AlaHis: 1.817 ± 1.148
1.817AlaIle: 1.817 ± 1.347
3.633AlaLys: 3.633 ± 1.258
5.45AlaLeu: 5.45 ± 2.474
0.908AlaMet: 0.908 ± 0.617
0.908AlaAsn: 0.908 ± 0.659
2.725AlaPro: 2.725 ± 1.363
1.817AlaGln: 1.817 ± 1.148
4.541AlaArg: 4.541 ± 2.599
2.725AlaSer: 2.725 ± 0.956
5.45AlaThr: 5.45 ± 2.446
2.725AlaVal: 2.725 ± 1.314
0.908AlaTrp: 0.908 ± 0.659
0.908AlaTyr: 0.908 ± 0.659
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.817CysCys: 1.817 ± 2.217
0.0CysAsp: 0.0 ± 0.0
0.908CysGlu: 0.908 ± 0.765
0.908CysPhe: 0.908 ± 1.061
1.817CysGly: 1.817 ± 0.975
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.817CysLys: 1.817 ± 0.79
0.908CysLeu: 0.908 ± 0.999
0.908CysMet: 0.908 ± 1.109
0.908CysAsn: 0.908 ± 0.659
1.817CysPro: 1.817 ± 2.217
0.908CysGln: 0.908 ± 0.659
0.908CysArg: 0.908 ± 0.659
4.541CysSer: 4.541 ± 3.866
0.908CysThr: 0.908 ± 0.765
1.817CysVal: 1.817 ± 1.531
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.817AspAla: 1.817 ± 1.319
0.908AspCys: 0.908 ± 1.019
3.633AspAsp: 3.633 ± 1.258
2.725AspGlu: 2.725 ± 1.237
0.908AspPhe: 0.908 ± 0.765
1.817AspGly: 1.817 ± 1.319
0.908AspHis: 0.908 ± 1.061
4.541AspIle: 4.541 ± 2.402
2.725AspLys: 2.725 ± 1.882
6.358AspLeu: 6.358 ± 1.79
0.0AspMet: 0.0 ± 0.0
1.817AspAsn: 1.817 ± 1.182
1.817AspPro: 1.817 ± 1.148
0.0AspGln: 0.0 ± 0.0
2.725AspArg: 2.725 ± 1.409
7.266AspSer: 7.266 ± 1.508
0.908AspThr: 0.908 ± 0.659
5.45AspVal: 5.45 ± 1.269
2.725AspTrp: 2.725 ± 1.317
1.817AspTyr: 1.817 ± 1.148
0.0AspXaa: 0.0 ± 0.0
Glu
3.633GluAla: 3.633 ± 1.268
0.0GluCys: 0.0 ± 0.0
0.0GluAsp: 0.0 ± 0.0
3.633GluGlu: 3.633 ± 2.026
2.725GluPhe: 2.725 ± 1.509
4.541GluGly: 4.541 ± 0.961
0.908GluHis: 0.908 ± 1.061
0.908GluIle: 0.908 ± 1.061
0.908GluLys: 0.908 ± 0.659
5.45GluLeu: 5.45 ± 1.876
0.0GluMet: 0.0 ± 0.0
6.358GluAsn: 6.358 ± 2.158
5.45GluPro: 5.45 ± 1.354
1.817GluGln: 1.817 ± 1.531
0.0GluArg: 0.0 ± 0.0
1.817GluSer: 1.817 ± 1.467
4.541GluThr: 4.541 ± 1.586
1.817GluVal: 1.817 ± 1.028
0.908GluTrp: 0.908 ± 1.019
0.908GluTyr: 0.908 ± 0.659
0.0GluXaa: 0.0 ± 0.0
Phe
0.908PheAla: 0.908 ± 0.659
0.908PheCys: 0.908 ± 0.765
2.725PheAsp: 2.725 ± 1.409
0.908PheGlu: 0.908 ± 0.659
2.725PhePhe: 2.725 ± 1.409
0.908PheGly: 0.908 ± 0.765
4.541PheHis: 4.541 ± 0.961
0.908PheIle: 0.908 ± 1.061
3.633PheLys: 3.633 ± 1.113
8.174PheLeu: 8.174 ± 2.449
0.908PheMet: 0.908 ± 0.659
2.725PheAsn: 2.725 ± 0.914
0.908PhePro: 0.908 ± 1.109
4.541PheGln: 4.541 ± 1.598
4.541PheArg: 4.541 ± 2.919
0.908PheSer: 0.908 ± 1.019
0.908PheThr: 0.908 ± 1.019
0.908PheVal: 0.908 ± 0.659
0.0PheTrp: 0.0 ± 0.0
2.725PheTyr: 2.725 ± 1.449
0.0PheXaa: 0.0 ± 0.0
Gly
1.817GlyAla: 1.817 ± 1.319
1.817GlyCys: 1.817 ± 1.182
4.541GlyAsp: 4.541 ± 1.773
2.725GlyGlu: 2.725 ± 1.363
1.817GlyPhe: 1.817 ± 1.347
2.725GlyGly: 2.725 ± 1.237
1.817GlyHis: 1.817 ± 1.148
3.633GlyIle: 3.633 ± 1.337
4.541GlyLys: 4.541 ± 1.968
0.0GlyLeu: 0.0 ± 0.0
0.908GlyMet: 0.908 ± 0.765
3.633GlyAsn: 3.633 ± 2.317
4.541GlyPro: 4.541 ± 1.968
2.725GlyGln: 2.725 ± 1.046
3.633GlyArg: 3.633 ± 1.356
2.725GlySer: 2.725 ± 1.023
1.817GlyThr: 1.817 ± 1.182
3.633GlyVal: 3.633 ± 2.654
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.725HisAla: 2.725 ± 1.629
3.633HisCys: 3.633 ± 1.876
2.725HisAsp: 2.725 ± 2.477
0.908HisGlu: 0.908 ± 0.659
3.633HisPhe: 3.633 ± 1.349
1.817HisGly: 1.817 ± 1.347
1.817HisHis: 1.817 ± 2.037
1.817HisIle: 1.817 ± 1.999
2.725HisLys: 2.725 ± 1.768
2.725HisLeu: 2.725 ± 1.317
0.0HisMet: 0.0 ± 0.0
2.725HisAsn: 2.725 ± 1.363
0.908HisPro: 0.908 ± 0.659
1.817HisGln: 1.817 ± 1.182
2.725HisArg: 2.725 ± 1.449
1.817HisSer: 1.817 ± 1.467
2.725HisThr: 2.725 ± 2.296
4.541HisVal: 4.541 ± 1.22
0.0HisTrp: 0.0 ± 0.0
0.908HisTyr: 0.908 ± 0.659
0.0HisXaa: 0.0 ± 0.0
Ile
0.908IleAla: 0.908 ± 1.019
0.0IleCys: 0.0 ± 0.0
1.817IleAsp: 1.817 ± 1.319
0.908IleGlu: 0.908 ± 0.659
2.725IlePhe: 2.725 ± 1.317
0.908IleGly: 0.908 ± 0.765
0.908IleHis: 0.908 ± 1.061
5.45IleIle: 5.45 ± 1.634
8.174IleLys: 8.174 ± 1.389
0.908IleLeu: 0.908 ± 0.659
1.817IleMet: 1.817 ± 1.283
5.45IleAsn: 5.45 ± 2.723
0.908IlePro: 0.908 ± 0.659
7.266IleGln: 7.266 ± 2.246
6.358IleArg: 6.358 ± 3.316
9.991IleSer: 9.991 ± 2.534
3.633IleThr: 3.633 ± 2.249
1.817IleVal: 1.817 ± 1.531
1.817IleTrp: 1.817 ± 2.123
2.725IleTyr: 2.725 ± 2.296
0.0IleXaa: 0.0 ± 0.0
Lys
2.725LysAla: 2.725 ± 2.159
1.817LysCys: 1.817 ± 1.028
1.817LysAsp: 1.817 ± 1.319
2.725LysGlu: 2.725 ± 1.237
2.725LysPhe: 2.725 ± 0.914
1.817LysGly: 1.817 ± 1.056
1.817LysHis: 1.817 ± 0.79
5.45LysIle: 5.45 ± 2.546
3.633LysLys: 3.633 ± 1.811
0.0LysLeu: 0.0 ± 0.0
0.0LysMet: 0.0 ± 0.0
6.358LysAsn: 6.358 ± 2.943
3.633LysPro: 3.633 ± 0.94
2.725LysGln: 2.725 ± 1.309
5.45LysArg: 5.45 ± 2.799
4.541LysSer: 4.541 ± 1.598
0.908LysThr: 0.908 ± 0.659
6.358LysVal: 6.358 ± 1.68
0.0LysTrp: 0.0 ± 0.0
5.45LysTyr: 5.45 ± 1.918
0.0LysXaa: 0.0 ± 0.0
Leu
0.908LeuAla: 0.908 ± 1.109
1.817LeuCys: 1.817 ± 1.319
5.45LeuAsp: 5.45 ± 2.127
4.541LeuGlu: 4.541 ± 1.586
0.908LeuPhe: 0.908 ± 0.659
4.541LeuGly: 4.541 ± 1.133
3.633LeuHis: 3.633 ± 1.514
3.633LeuIle: 3.633 ± 2.384
6.358LeuLys: 6.358 ± 2.783
4.541LeuLeu: 4.541 ± 2.378
1.817LeuMet: 1.817 ± 1.327
6.358LeuAsn: 6.358 ± 0.853
0.908LeuPro: 0.908 ± 1.019
2.725LeuGln: 2.725 ± 1.463
3.633LeuArg: 3.633 ± 1.208
3.633LeuSer: 3.633 ± 1.989
3.633LeuThr: 3.633 ± 2.112
3.633LeuVal: 3.633 ± 1.579
0.0LeuTrp: 0.0 ± 0.0
3.633LeuTyr: 3.633 ± 1.817
0.0LeuXaa: 0.0 ± 0.0
Met
1.817MetAla: 1.817 ± 0.79
0.908MetCys: 0.908 ± 0.999
3.633MetAsp: 3.633 ± 1.777
0.0MetGlu: 0.0 ± 0.0
2.725MetPhe: 2.725 ± 1.711
2.725MetGly: 2.725 ± 1.172
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.817MetLys: 1.817 ± 1.531
0.908MetLeu: 0.908 ± 1.109
0.0MetMet: 0.0 ± 0.0
0.908MetAsn: 0.908 ± 1.061
0.0MetPro: 0.0 ± 0.0
0.908MetGln: 0.908 ± 1.019
0.908MetArg: 0.908 ± 0.765
2.725MetSer: 2.725 ± 1.046
0.908MetThr: 0.908 ± 0.999
0.0MetVal: 0.0 ± 0.0
1.817MetTrp: 1.817 ± 1.148
1.817MetTyr: 1.817 ± 1.531
0.0MetXaa: 0.0 ± 0.0
Asn
2.725AsnAla: 2.725 ± 1.046
1.817AsnCys: 1.817 ± 0.975
2.725AsnAsp: 2.725 ± 1.237
3.633AsnGlu: 3.633 ± 0.94
1.817AsnPhe: 1.817 ± 1.141
2.725AsnGly: 2.725 ± 1.249
7.266AsnHis: 7.266 ± 2.685
4.541AsnIle: 4.541 ± 1.231
2.725AsnLys: 2.725 ± 1.237
4.541AsnLeu: 4.541 ± 1.904
1.817AsnMet: 1.817 ± 1.637
1.817AsnAsn: 1.817 ± 2.123
3.633AsnPro: 3.633 ± 0.971
3.633AsnGln: 3.633 ± 1.818
0.908AsnArg: 0.908 ± 1.019
5.45AsnSer: 5.45 ± 1.87
2.725AsnThr: 2.725 ± 1.463
4.541AsnVal: 4.541 ± 2.273
0.908AsnTrp: 0.908 ± 0.659
1.817AsnTyr: 1.817 ± 1.319
0.0AsnXaa: 0.0 ± 0.0
Pro
0.908ProAla: 0.908 ± 0.659
1.817ProCys: 1.817 ± 1.164
1.817ProAsp: 1.817 ± 0.79
0.908ProGlu: 0.908 ± 1.109
1.817ProPhe: 1.817 ± 1.028
2.725ProGly: 2.725 ± 1.237
4.541ProHis: 4.541 ± 2.608
4.541ProIle: 4.541 ± 1.672
4.541ProLys: 4.541 ± 2.599
2.725ProLeu: 2.725 ± 1.463
3.633ProMet: 3.633 ± 1.735
3.633ProAsn: 3.633 ± 1.349
1.817ProPro: 1.817 ± 1.319
5.45ProGln: 5.45 ± 3.455
3.633ProArg: 3.633 ± 1.669
4.541ProSer: 4.541 ± 2.562
3.633ProThr: 3.633 ± 2.637
2.725ProVal: 2.725 ± 1.71
0.908ProTrp: 0.908 ± 0.659
2.725ProTyr: 2.725 ± 1.409
0.0ProXaa: 0.0 ± 0.0
Gln
6.358GlnAla: 6.358 ± 2.92
0.0GlnCys: 0.0 ± 0.0
1.817GlnAsp: 1.817 ± 0.975
3.633GlnGlu: 3.633 ± 1.14
1.817GlnPhe: 1.817 ± 1.319
2.725GlnGly: 2.725 ± 1.237
2.725GlnHis: 2.725 ± 2.355
3.633GlnIle: 3.633 ± 1.878
0.0GlnLys: 0.0 ± 0.0
2.725GlnLeu: 2.725 ± 1.352
0.908GlnMet: 0.908 ± 1.019
3.633GlnAsn: 3.633 ± 1.982
6.358GlnPro: 6.358 ± 3.755
1.817GlnGln: 1.817 ± 1.148
3.633GlnArg: 3.633 ± 1.297
4.541GlnSer: 4.541 ± 0.961
2.725GlnThr: 2.725 ± 2.096
4.541GlnVal: 4.541 ± 2.087
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.633ArgAla: 3.633 ± 1.208
1.817ArgCys: 1.817 ± 1.164
5.45ArgAsp: 5.45 ± 2.446
3.633ArgGlu: 3.633 ± 1.514
7.266ArgPhe: 7.266 ± 1.987
3.633ArgGly: 3.633 ± 1.431
1.817ArgHis: 1.817 ± 1.347
4.541ArgIle: 4.541 ± 1.339
3.633ArgLys: 3.633 ± 1.795
2.725ArgLeu: 2.725 ± 1.438
0.908ArgMet: 0.908 ± 0.765
0.0ArgAsn: 0.0 ± 0.0
5.45ArgPro: 5.45 ± 1.876
0.908ArgGln: 0.908 ± 1.109
5.45ArgArg: 5.45 ± 2.906
4.541ArgSer: 4.541 ± 1.561
3.633ArgThr: 3.633 ± 1.441
2.725ArgVal: 2.725 ± 1.449
0.0ArgTrp: 0.0 ± 0.0
1.817ArgTyr: 1.817 ± 1.598
0.0ArgXaa: 0.0 ± 0.0
Ser
2.725SerAla: 2.725 ± 1.978
0.0SerCys: 0.0 ± 0.0
4.541SerAsp: 4.541 ± 2.036
1.817SerGlu: 1.817 ± 1.319
2.725SerPhe: 2.725 ± 1.352
3.633SerGly: 3.633 ± 1.431
2.725SerHis: 2.725 ± 1.449
9.083SerIle: 9.083 ± 2.381
3.633SerLys: 3.633 ± 1.396
5.45SerLeu: 5.45 ± 2.21
0.908SerMet: 0.908 ± 0.999
8.174SerAsn: 8.174 ± 2.455
8.174SerPro: 8.174 ± 1.784
6.358SerGln: 6.358 ± 3.443
2.725SerArg: 2.725 ± 0.914
10.899SerSer: 10.899 ± 3.886
5.45SerThr: 5.45 ± 3.355
2.725SerVal: 2.725 ± 3.326
0.908SerTrp: 0.908 ± 0.765
3.633SerTyr: 3.633 ± 1.14
0.0SerXaa: 0.0 ± 0.0
Thr
2.725ThrAla: 2.725 ± 1.449
0.0ThrCys: 0.0 ± 0.0
0.908ThrAsp: 0.908 ± 0.999
3.633ThrGlu: 3.633 ± 2.081
1.817ThrPhe: 1.817 ± 1.056
4.541ThrGly: 4.541 ± 1.745
4.541ThrHis: 4.541 ± 2.423
2.725ThrIle: 2.725 ± 1.463
0.908ThrLys: 0.908 ± 0.659
3.633ThrLeu: 3.633 ± 1.542
1.817ThrMet: 1.817 ± 0.79
4.541ThrAsn: 4.541 ± 1.968
3.633ThrPro: 3.633 ± 1.887
2.725ThrGln: 2.725 ± 1.352
1.817ThrArg: 1.817 ± 1.164
2.725ThrSer: 2.725 ± 1.352
0.908ThrThr: 0.908 ± 1.061
2.725ThrVal: 2.725 ± 1.409
0.908ThrTrp: 0.908 ± 0.999
3.633ThrTyr: 3.633 ± 1.396
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
0.908ValCys: 0.908 ± 0.659
4.541ValAsp: 4.541 ± 1.729
1.817ValGlu: 1.817 ± 2.217
2.725ValPhe: 2.725 ± 2.067
1.817ValGly: 1.817 ± 1.173
0.908ValHis: 0.908 ± 1.109
4.541ValIle: 4.541 ± 2.832
3.633ValLys: 3.633 ± 2.125
2.725ValLeu: 2.725 ± 1.983
3.633ValMet: 3.633 ± 1.337
0.0ValAsn: 0.0 ± 0.0
4.541ValPro: 4.541 ± 1.453
4.541ValGln: 4.541 ± 1.867
3.633ValArg: 3.633 ± 2.263
8.174ValSer: 8.174 ± 2.717
3.633ValThr: 3.633 ± 1.337
0.908ValVal: 0.908 ± 1.109
1.817ValTrp: 1.817 ± 0.79
1.817ValTyr: 1.817 ± 0.79
0.0ValXaa: 0.0 ± 0.0
Trp
1.817TrpAla: 1.817 ± 1.319
0.0TrpCys: 0.0 ± 0.0
0.908TrpAsp: 0.908 ± 1.109
0.908TrpGlu: 0.908 ± 1.061
0.0TrpPhe: 0.0 ± 0.0
0.908TrpGly: 0.908 ± 0.659
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.908TrpMet: 0.908 ± 0.765
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.908TrpGln: 0.908 ± 0.659
1.817TrpArg: 1.817 ± 0.975
0.908TrpSer: 0.908 ± 1.019
1.817TrpThr: 1.817 ± 1.141
0.908TrpVal: 0.908 ± 0.659
0.0TrpTrp: 0.0 ± 0.0
1.817TrpTyr: 1.817 ± 1.056
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.817TyrAla: 1.817 ± 0.79
0.0TyrCys: 0.0 ± 0.0
1.817TyrAsp: 1.817 ± 1.141
4.541TyrGlu: 4.541 ± 1.396
3.633TyrPhe: 3.633 ± 1.337
1.817TyrGly: 1.817 ± 0.79
0.0TyrHis: 0.0 ± 0.0
2.725TyrIle: 2.725 ± 1.978
0.908TyrLys: 0.908 ± 1.061
6.358TyrLeu: 6.358 ± 2.002
1.817TyrMet: 1.817 ± 1.053
2.725TyrAsn: 2.725 ± 1.023
1.817TyrPro: 1.817 ± 1.056
0.0TyrGln: 0.0 ± 0.0
4.541TyrArg: 4.541 ± 2.867
1.817TyrSer: 1.817 ± 0.79
0.0TyrThr: 0.0 ± 0.0
1.817TyrVal: 1.817 ± 1.148
0.0TyrTrp: 0.0 ± 0.0
0.908TyrTyr: 0.908 ± 1.019
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1102 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski