Amino acid dipepetide frequency for Tortoise microvirus 60

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.646AlaAla: 4.646 ± 1.263
1.161AlaCys: 1.161 ± 0.817
4.065AlaAsp: 4.065 ± 2.257
6.969AlaGlu: 6.969 ± 3.283
5.807AlaPhe: 5.807 ± 1.298
5.226AlaGly: 5.226 ± 1.534
0.581AlaHis: 0.581 ± 0.403
2.323AlaIle: 2.323 ± 1.392
2.904AlaLys: 2.904 ± 1.527
5.807AlaLeu: 5.807 ± 2.294
2.904AlaMet: 2.904 ± 2.05
4.646AlaAsn: 4.646 ± 2.012
4.065AlaPro: 4.065 ± 0.963
4.065AlaGln: 4.065 ± 2.244
5.807AlaArg: 5.807 ± 1.309
8.13AlaSer: 8.13 ± 3.681
5.226AlaThr: 5.226 ± 1.678
4.646AlaVal: 4.646 ± 0.914
0.581AlaTrp: 0.581 ± 0.573
1.742AlaTyr: 1.742 ± 0.697
0.0AlaXaa: 0.0 ± 0.0
Cys
0.581CysAla: 0.581 ± 0.573
0.581CysCys: 0.581 ± 0.878
1.161CysAsp: 1.161 ± 0.638
0.0CysGlu: 0.0 ± 0.0
2.323CysPhe: 2.323 ± 2.426
0.581CysGly: 0.581 ± 0.573
0.0CysHis: 0.0 ± 0.0
0.581CysIle: 0.581 ± 0.878
1.161CysLys: 1.161 ± 1.146
0.581CysLeu: 0.581 ± 0.872
1.161CysMet: 1.161 ± 0.81
1.161CysAsn: 1.161 ± 1.191
0.581CysPro: 0.581 ± 0.878
0.0CysGln: 0.0 ± 0.0
1.742CysArg: 1.742 ± 1.11
0.0CysSer: 0.0 ± 0.0
1.161CysThr: 1.161 ± 1.146
1.161CysVal: 1.161 ± 0.97
0.0CysTrp: 0.0 ± 0.0
1.161CysTyr: 1.161 ± 0.817
0.0CysXaa: 0.0 ± 0.0
Asp
6.388AspAla: 6.388 ± 2.37
0.581AspCys: 0.581 ± 0.573
6.388AspAsp: 6.388 ± 2.546
2.323AspGlu: 2.323 ± 1.392
6.969AspPhe: 6.969 ± 1.84
1.742AspGly: 1.742 ± 0.645
0.581AspHis: 0.581 ± 0.573
5.226AspIle: 5.226 ± 1.043
5.226AspLys: 5.226 ± 1.741
7.549AspLeu: 7.549 ± 2.328
2.323AspMet: 2.323 ± 1.367
3.484AspAsn: 3.484 ± 1.172
0.581AspPro: 0.581 ± 0.878
0.581AspGln: 0.581 ± 0.51
2.323AspArg: 2.323 ± 0.75
5.226AspSer: 5.226 ± 1.348
4.065AspThr: 4.065 ± 1.664
5.226AspVal: 5.226 ± 2.635
1.161AspTrp: 1.161 ± 0.613
4.065AspTyr: 4.065 ± 1.083
0.0AspXaa: 0.0 ± 0.0
Glu
1.161GluAla: 1.161 ± 0.77
0.0GluCys: 0.0 ± 0.0
1.161GluAsp: 1.161 ± 1.02
2.323GluGlu: 2.323 ± 1.017
3.484GluPhe: 3.484 ± 1.656
1.161GluGly: 1.161 ± 0.77
0.581GluHis: 0.581 ± 0.878
0.581GluIle: 0.581 ± 0.611
4.065GluLys: 4.065 ± 2.235
8.13GluLeu: 8.13 ± 2.89
1.161GluMet: 1.161 ± 0.825
1.742GluAsn: 1.742 ± 0.913
0.581GluPro: 0.581 ± 0.51
1.742GluGln: 1.742 ± 0.959
2.904GluArg: 2.904 ± 0.988
6.969GluSer: 6.969 ± 2.708
4.065GluThr: 4.065 ± 1.59
2.904GluVal: 2.904 ± 0.869
0.581GluTrp: 0.581 ± 0.403
1.742GluTyr: 1.742 ± 1.33
0.0GluXaa: 0.0 ± 0.0
Phe
4.065PheAla: 4.065 ± 1.395
1.161PheCys: 1.161 ± 1.146
4.065PheAsp: 4.065 ± 0.809
2.323PheGlu: 2.323 ± 1.043
3.484PhePhe: 3.484 ± 0.874
3.484PheGly: 3.484 ± 1.807
0.581PheHis: 0.581 ± 0.878
2.323PheIle: 2.323 ± 1.441
2.904PheLys: 2.904 ± 1.259
4.065PheLeu: 4.065 ± 0.99
1.161PheMet: 1.161 ± 0.694
5.807PheAsn: 5.807 ± 2.031
2.323PhePro: 2.323 ± 1.046
1.742PheGln: 1.742 ± 0.883
5.226PheArg: 5.226 ± 1.606
9.292PheSer: 9.292 ± 1.341
2.904PheThr: 2.904 ± 0.94
0.581PheVal: 0.581 ± 0.611
1.161PheTrp: 1.161 ± 0.807
0.581PheTyr: 0.581 ± 0.403
0.0PheXaa: 0.0 ± 0.0
Gly
6.969GlyAla: 6.969 ± 3.472
0.0GlyCys: 0.0 ± 0.0
4.646GlyAsp: 4.646 ± 1.994
0.581GlyGlu: 0.581 ± 0.573
1.742GlyPhe: 1.742 ± 0.822
5.226GlyGly: 5.226 ± 1.984
2.323GlyHis: 2.323 ± 1.236
4.646GlyIle: 4.646 ± 1.479
2.904GlyLys: 2.904 ± 1.519
6.969GlyLeu: 6.969 ± 2.371
3.484GlyMet: 3.484 ± 1.867
3.484GlyAsn: 3.484 ± 1.57
0.0GlyPro: 0.0 ± 0.0
0.0GlyGln: 0.0 ± 0.0
1.161GlyArg: 1.161 ± 0.817
7.549GlySer: 7.549 ± 2.334
2.323GlyThr: 2.323 ± 0.75
2.323GlyVal: 2.323 ± 0.747
0.0GlyTrp: 0.0 ± 0.0
4.646GlyTyr: 4.646 ± 1.985
0.0GlyXaa: 0.0 ± 0.0
His
1.742HisAla: 1.742 ± 0.728
0.0HisCys: 0.0 ± 0.0
1.161HisAsp: 1.161 ± 1.155
0.0HisGlu: 0.0 ± 0.0
0.581HisPhe: 0.581 ± 0.403
1.742HisGly: 1.742 ± 0.913
0.0HisHis: 0.0 ± 0.0
0.581HisIle: 0.581 ± 0.573
0.0HisLys: 0.0 ± 0.0
2.904HisLeu: 2.904 ± 1.454
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
1.161HisArg: 1.161 ± 0.845
0.0HisSer: 0.0 ± 0.0
1.161HisThr: 1.161 ± 1.755
0.581HisVal: 0.581 ± 0.573
0.0HisTrp: 0.0 ± 0.0
1.161HisTyr: 1.161 ± 0.613
0.0HisXaa: 0.0 ± 0.0
Ile
3.484IleAla: 3.484 ± 1.765
0.581IleCys: 0.581 ± 0.878
2.904IleAsp: 2.904 ± 1.725
4.646IleGlu: 4.646 ± 3.681
1.161IlePhe: 1.161 ± 0.886
3.484IleGly: 3.484 ± 1.287
0.581IleHis: 0.581 ± 0.403
1.161IleIle: 1.161 ± 0.459
2.904IleLys: 2.904 ± 1.545
2.904IleLeu: 2.904 ± 0.997
1.161IleMet: 1.161 ± 0.807
2.323IleAsn: 2.323 ± 0.75
6.969IlePro: 6.969 ± 3.088
1.742IleGln: 1.742 ± 0.876
2.904IleArg: 2.904 ± 1.645
2.904IleSer: 2.904 ± 0.914
2.323IleThr: 2.323 ± 0.949
2.904IleVal: 2.904 ± 0.914
0.0IleTrp: 0.0 ± 0.0
1.742IleTyr: 1.742 ± 0.959
0.0IleXaa: 0.0 ± 0.0
Lys
7.549LysAla: 7.549 ± 3.431
0.581LysCys: 0.581 ± 0.674
2.904LysAsp: 2.904 ± 2.033
1.742LysGlu: 1.742 ± 1.11
1.161LysPhe: 1.161 ± 1.146
2.904LysGly: 2.904 ± 1.259
0.581LysHis: 0.581 ± 0.573
1.161LysIle: 1.161 ± 0.92
2.323LysLys: 2.323 ± 1.09
2.323LysLeu: 2.323 ± 0.949
3.484LysMet: 3.484 ± 0.599
4.646LysAsn: 4.646 ± 1.561
0.581LysPro: 0.581 ± 0.872
1.742LysGln: 1.742 ± 1.202
2.323LysArg: 2.323 ± 1.367
3.484LysSer: 3.484 ± 1.519
1.742LysThr: 1.742 ± 0.761
0.581LysVal: 0.581 ± 0.611
0.0LysTrp: 0.0 ± 0.0
2.323LysTyr: 2.323 ± 1.804
0.0LysXaa: 0.0 ± 0.0
Leu
5.226LeuAla: 5.226 ± 1.269
1.742LeuCys: 1.742 ± 1.251
7.549LeuAsp: 7.549 ± 2.702
5.807LeuGlu: 5.807 ± 2.675
5.226LeuPhe: 5.226 ± 1.922
5.807LeuGly: 5.807 ± 1.226
0.0LeuHis: 0.0 ± 0.0
3.484LeuIle: 3.484 ± 1.319
2.323LeuLys: 2.323 ± 1.941
2.904LeuLeu: 2.904 ± 1.11
1.161LeuMet: 1.161 ± 0.807
4.646LeuAsn: 4.646 ± 2.41
4.646LeuPro: 4.646 ± 2.728
5.226LeuGln: 5.226 ± 1.204
4.065LeuArg: 4.065 ± 2.208
9.872LeuSer: 9.872 ± 1.911
4.065LeuThr: 4.065 ± 1.488
3.484LeuVal: 3.484 ± 0.967
1.161LeuTrp: 1.161 ± 0.807
4.646LeuTyr: 4.646 ± 2.87
0.0LeuXaa: 0.0 ± 0.0
Met
4.065MetAla: 4.065 ± 2.244
0.581MetCys: 0.581 ± 0.674
2.904MetAsp: 2.904 ± 1.204
0.0MetGlu: 0.0 ± 0.0
1.742MetPhe: 1.742 ± 0.697
1.742MetGly: 1.742 ± 0.897
0.0MetHis: 0.0 ± 0.0
2.323MetIle: 2.323 ± 1.178
0.581MetLys: 0.581 ± 0.872
1.161MetLeu: 1.161 ± 0.77
1.161MetMet: 1.161 ± 0.459
2.904MetAsn: 2.904 ± 1.865
0.0MetPro: 0.0 ± 0.0
1.161MetGln: 1.161 ± 0.459
0.581MetArg: 0.581 ± 0.573
3.484MetSer: 3.484 ± 1.045
1.742MetThr: 1.742 ± 0.806
0.581MetVal: 0.581 ± 0.403
0.0MetTrp: 0.0 ± 0.0
2.904MetTyr: 2.904 ± 1.419
0.0MetXaa: 0.0 ± 0.0
Asn
4.646AsnAla: 4.646 ± 2.226
1.161AsnCys: 1.161 ± 0.886
3.484AsnAsp: 3.484 ± 0.941
1.742AsnGlu: 1.742 ± 1.11
4.065AsnPhe: 4.065 ± 0.883
1.742AsnGly: 1.742 ± 0.817
0.0AsnHis: 0.0 ± 0.0
2.323AsnIle: 2.323 ± 0.747
2.904AsnLys: 2.904 ± 0.706
4.646AsnLeu: 4.646 ± 0.818
1.742AsnMet: 1.742 ± 0.883
2.904AsnAsn: 2.904 ± 0.706
1.742AsnPro: 1.742 ± 0.761
1.161AsnGln: 1.161 ± 0.807
4.065AsnArg: 4.065 ± 1.698
4.646AsnSer: 4.646 ± 2.354
3.484AsnThr: 3.484 ± 1.282
4.065AsnVal: 4.065 ± 1.116
0.581AsnTrp: 0.581 ± 0.878
4.065AsnTyr: 4.065 ± 1.671
0.0AsnXaa: 0.0 ± 0.0
Pro
4.065ProAla: 4.065 ± 1.058
0.581ProCys: 0.581 ± 0.573
3.484ProAsp: 3.484 ± 1.945
1.742ProGlu: 1.742 ± 1.386
1.742ProPhe: 1.742 ± 0.857
1.742ProGly: 1.742 ± 0.697
0.581ProHis: 0.581 ± 0.573
5.226ProIle: 5.226 ± 2.309
1.161ProLys: 1.161 ± 0.97
2.904ProLeu: 2.904 ± 1.018
1.742ProMet: 1.742 ± 0.761
0.581ProAsn: 0.581 ± 0.403
0.581ProPro: 0.581 ± 0.403
2.323ProGln: 2.323 ± 1.265
1.742ProArg: 1.742 ± 1.061
4.646ProSer: 4.646 ± 1.495
1.161ProThr: 1.161 ± 0.807
4.646ProVal: 4.646 ± 1.789
0.0ProTrp: 0.0 ± 0.0
2.323ProTyr: 2.323 ± 1.613
0.0ProXaa: 0.0 ± 0.0
Gln
1.161GlnAla: 1.161 ± 0.638
1.161GlnCys: 1.161 ± 0.886
2.904GlnAsp: 2.904 ± 1.412
2.323GlnGlu: 2.323 ± 0.93
3.484GlnPhe: 3.484 ± 1.765
3.484GlnGly: 3.484 ± 0.874
0.0GlnHis: 0.0 ± 0.0
2.323GlnIle: 2.323 ± 0.747
0.581GlnLys: 0.581 ± 0.51
1.161GlnLeu: 1.161 ± 0.888
0.581GlnMet: 0.581 ± 0.51
1.161GlnAsn: 1.161 ± 0.607
0.581GlnPro: 0.581 ± 0.403
2.904GlnGln: 2.904 ± 2.551
3.484GlnArg: 3.484 ± 0.626
4.065GlnSer: 4.065 ± 0.8
2.323GlnThr: 2.323 ± 1.613
0.581GlnVal: 0.581 ± 0.403
0.581GlnTrp: 0.581 ± 0.51
1.742GlnTyr: 1.742 ± 0.883
0.0GlnXaa: 0.0 ± 0.0
Arg
4.065ArgAla: 4.065 ± 1.415
0.581ArgCys: 0.581 ± 0.573
5.226ArgAsp: 5.226 ± 0.838
5.226ArgGlu: 5.226 ± 1.801
1.161ArgPhe: 1.161 ± 0.77
2.323ArgGly: 2.323 ± 1.773
0.581ArgHis: 0.581 ± 0.403
2.323ArgIle: 2.323 ± 1.348
3.484ArgLys: 3.484 ± 1.955
6.969ArgLeu: 6.969 ± 2.2
1.742ArgMet: 1.742 ± 0.956
0.581ArgAsn: 0.581 ± 0.573
5.807ArgPro: 5.807 ± 2.859
2.323ArgGln: 2.323 ± 0.918
2.904ArgArg: 2.904 ± 1.703
5.807ArgSer: 5.807 ± 3.072
0.581ArgThr: 0.581 ± 0.51
1.742ArgVal: 1.742 ± 0.761
0.0ArgTrp: 0.0 ± 0.0
2.904ArgTyr: 2.904 ± 1.489
0.0ArgXaa: 0.0 ± 0.0
Ser
9.872SerAla: 9.872 ± 2.351
1.742SerCys: 1.742 ± 1.72
5.807SerAsp: 5.807 ± 0.866
2.904SerGlu: 2.904 ± 1.362
7.549SerPhe: 7.549 ± 1.645
13.357SerGly: 13.357 ± 4.429
2.323SerHis: 2.323 ± 1.036
4.065SerIle: 4.065 ± 1.658
1.161SerLys: 1.161 ± 0.613
6.969SerLeu: 6.969 ± 1.02
2.323SerMet: 2.323 ± 0.636
4.065SerAsn: 4.065 ± 1.72
4.065SerPro: 4.065 ± 1.153
3.484SerGln: 3.484 ± 1.068
3.484SerArg: 3.484 ± 1.28
12.195SerSer: 12.195 ± 5.216
3.484SerThr: 3.484 ± 1.395
8.13SerVal: 8.13 ± 2.363
0.0SerTrp: 0.0 ± 0.0
4.646SerTyr: 4.646 ± 1.907
0.0SerXaa: 0.0 ± 0.0
Thr
4.065ThrAla: 4.065 ± 0.754
0.0ThrCys: 0.0 ± 0.0
1.742ThrAsp: 1.742 ± 1.21
2.323ThrGlu: 2.323 ± 0.882
4.646ThrPhe: 4.646 ± 1.711
1.742ThrGly: 1.742 ± 0.913
1.161ThrHis: 1.161 ± 0.888
2.904ThrIle: 2.904 ± 0.914
3.484ThrLys: 3.484 ± 0.97
3.484ThrLeu: 3.484 ± 1.708
0.581ThrMet: 0.581 ± 0.403
2.904ThrAsn: 2.904 ± 0.831
1.161ThrPro: 1.161 ± 0.807
1.742ThrGln: 1.742 ± 0.883
4.065ThrArg: 4.065 ± 0.82
3.484ThrSer: 3.484 ± 1.068
0.581ThrThr: 0.581 ± 0.403
4.065ThrVal: 4.065 ± 1.314
0.581ThrTrp: 0.581 ± 0.403
1.742ThrTyr: 1.742 ± 1.23
0.0ThrXaa: 0.0 ± 0.0
Val
4.646ValAla: 4.646 ± 0.776
0.581ValCys: 0.581 ± 0.872
4.646ValAsp: 4.646 ± 1.341
1.742ValGlu: 1.742 ± 1.04
1.161ValPhe: 1.161 ± 0.807
0.581ValGly: 0.581 ± 0.403
1.161ValHis: 1.161 ± 0.886
1.161ValIle: 1.161 ± 0.807
2.323ValLys: 2.323 ± 1.497
5.807ValLeu: 5.807 ± 2.016
0.581ValMet: 0.581 ± 0.878
4.646ValAsn: 4.646 ± 1.912
5.807ValPro: 5.807 ± 2.039
2.323ValGln: 2.323 ± 1.322
2.904ValArg: 2.904 ± 1.109
6.388ValSer: 6.388 ± 1.56
0.581ValThr: 0.581 ± 0.573
2.904ValVal: 2.904 ± 1.814
0.0ValTrp: 0.0 ± 0.0
1.742ValTyr: 1.742 ± 1.061
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.581TrpCys: 0.581 ± 0.878
0.581TrpAsp: 0.581 ± 0.51
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.161TrpIle: 1.161 ± 0.807
0.581TrpLys: 0.581 ± 0.573
0.581TrpLeu: 0.581 ± 0.403
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.581TrpPro: 0.581 ± 0.403
0.581TrpGln: 0.581 ± 0.573
0.0TrpArg: 0.0 ± 0.0
0.581TrpSer: 0.581 ± 0.51
0.581TrpThr: 0.581 ± 0.403
0.581TrpVal: 0.581 ± 0.403
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.904TyrAla: 2.904 ± 1.049
2.323TyrCys: 2.323 ± 1.715
5.226TyrAsp: 5.226 ± 2.6
2.323TyrGlu: 2.323 ± 1.12
1.742TyrPhe: 1.742 ± 0.876
2.904TyrGly: 2.904 ± 1.361
1.161TyrHis: 1.161 ± 0.97
2.904TyrIle: 2.904 ± 1.256
1.161TyrLys: 1.161 ± 0.638
5.226TyrLeu: 5.226 ± 2.723
0.581TyrMet: 0.581 ± 0.403
3.484TyrAsn: 3.484 ± 1.158
2.323TyrPro: 2.323 ± 1.191
1.742TyrGln: 1.742 ± 0.857
3.484TyrArg: 3.484 ± 1.696
3.484TyrSer: 3.484 ± 1.595
2.904TyrThr: 2.904 ± 1.569
0.0TyrVal: 0.0 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
2.323TyrTyr: 2.323 ± 1.043
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (1723 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski