Amino acid dipepetide frequency for Hubei diptera virus 18

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.963AlaAla: 1.963 ± 1.307
2.944AlaCys: 2.944 ± 1.96
0.981AlaAsp: 0.981 ± 0.653
3.925AlaGlu: 3.925 ± 0.112
2.944AlaPhe: 2.944 ± 0.766
2.944AlaGly: 2.944 ± 2.129
0.981AlaHis: 0.981 ± 0.653
3.925AlaIle: 3.925 ± 1.251
3.925AlaLys: 3.925 ± 0.112
2.944AlaLeu: 2.944 ± 0.766
0.0AlaMet: 0.0 ± 0.0
1.963AlaAsn: 1.963 ± 0.056
4.907AlaPro: 4.907 ± 2.185
2.944AlaGln: 2.944 ± 0.597
5.888AlaArg: 5.888 ± 2.557
3.925AlaSer: 3.925 ± 0.112
0.981AlaThr: 0.981 ± 0.653
0.981AlaVal: 0.981 ± 0.71
0.981AlaTrp: 0.981 ± 0.71
2.944AlaTyr: 2.944 ± 0.597
0.0AlaXaa: 0.0 ± 0.0
Cys
1.963CysAla: 1.963 ± 1.307
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.963CysGlu: 1.963 ± 0.056
0.981CysPhe: 0.981 ± 0.653
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.963CysIle: 1.963 ± 0.056
2.944CysLys: 2.944 ± 1.96
2.944CysLeu: 2.944 ± 0.597
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.981CysPro: 0.981 ± 0.71
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.963CysSer: 1.963 ± 1.419
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.981CysTrp: 0.981 ± 0.71
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.869AspAla: 6.869 ± 0.878
1.963AspCys: 1.963 ± 0.056
2.944AspAsp: 2.944 ± 0.597
0.0AspGlu: 0.0 ± 0.0
3.925AspPhe: 3.925 ± 2.613
2.944AspGly: 2.944 ± 0.597
0.981AspHis: 0.981 ± 0.653
3.925AspIle: 3.925 ± 1.475
3.925AspLys: 3.925 ± 2.613
1.963AspLeu: 1.963 ± 1.307
2.944AspMet: 2.944 ± 0.766
2.944AspAsn: 2.944 ± 0.766
4.907AspPro: 4.907 ± 0.822
1.963AspGln: 1.963 ± 1.307
0.981AspArg: 0.981 ± 0.653
1.963AspSer: 1.963 ± 1.307
1.963AspThr: 1.963 ± 0.056
2.944AspVal: 2.944 ± 0.597
0.981AspTrp: 0.981 ± 0.653
1.963AspTyr: 1.963 ± 1.307
0.0AspXaa: 0.0 ± 0.0
Glu
3.925GluAla: 3.925 ± 1.475
0.0GluCys: 0.0 ± 0.0
3.925GluAsp: 3.925 ± 2.613
4.907GluGlu: 4.907 ± 2.185
3.925GluPhe: 3.925 ± 0.112
0.981GluGly: 0.981 ± 0.71
1.963GluHis: 1.963 ± 1.307
3.925GluIle: 3.925 ± 0.112
1.963GluLys: 1.963 ± 1.307
6.869GluLeu: 6.869 ± 0.878
0.981GluMet: 0.981 ± 0.653
7.851GluAsn: 7.851 ± 1.588
0.0GluPro: 0.0 ± 0.0
0.981GluGln: 0.981 ± 0.71
1.963GluArg: 1.963 ± 0.056
3.925GluSer: 3.925 ± 1.475
0.981GluThr: 0.981 ± 0.653
2.944GluVal: 2.944 ± 0.597
0.981GluTrp: 0.981 ± 0.71
0.981GluTyr: 0.981 ± 0.653
0.0GluXaa: 0.0 ± 0.0
Phe
3.925PheAla: 3.925 ± 0.112
2.944PheCys: 2.944 ± 2.129
4.907PheAsp: 4.907 ± 1.904
2.944PheGlu: 2.944 ± 0.597
4.907PhePhe: 4.907 ± 0.822
2.944PheGly: 2.944 ± 0.597
1.963PheHis: 1.963 ± 1.307
2.944PheIle: 2.944 ± 0.597
3.925PheLys: 3.925 ± 0.112
6.869PheLeu: 6.869 ± 3.211
0.0PheMet: 0.0 ± 0.0
3.925PheAsn: 3.925 ± 0.112
6.869PhePro: 6.869 ± 0.485
0.0PheGln: 0.0 ± 0.0
0.981PheArg: 0.981 ± 0.653
0.0PheSer: 0.0 ± 0.0
3.925PheThr: 3.925 ± 1.475
4.907PheVal: 4.907 ± 0.822
0.0PheTrp: 0.0 ± 0.0
1.963PheTyr: 1.963 ± 0.056
0.0PheXaa: 0.0 ± 0.0
Gly
1.963GlyAla: 1.963 ± 0.056
0.981GlyCys: 0.981 ± 0.653
1.963GlyAsp: 1.963 ± 1.307
2.944GlyGlu: 2.944 ± 0.597
3.925GlyPhe: 3.925 ± 0.112
5.888GlyGly: 5.888 ± 1.531
0.0GlyHis: 0.0 ± 0.0
1.963GlyIle: 1.963 ± 1.419
3.925GlyLys: 3.925 ± 1.251
4.907GlyLeu: 4.907 ± 0.541
2.944GlyMet: 2.944 ± 1.96
2.944GlyAsn: 2.944 ± 0.766
0.981GlyPro: 0.981 ± 0.71
3.925GlyGln: 3.925 ± 1.475
3.925GlyArg: 3.925 ± 2.838
4.907GlySer: 4.907 ± 2.185
0.0GlyThr: 0.0 ± 0.0
1.963GlyVal: 1.963 ± 1.307
0.981GlyTrp: 0.981 ± 0.71
8.832GlyTyr: 8.832 ± 0.429
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.981HisGlu: 0.981 ± 0.653
1.963HisPhe: 1.963 ± 0.056
1.963HisGly: 1.963 ± 0.056
0.0HisHis: 0.0 ± 0.0
0.981HisIle: 0.981 ± 0.653
3.925HisLys: 3.925 ± 2.613
3.925HisLeu: 3.925 ± 0.112
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
0.981HisArg: 0.981 ± 0.653
1.963HisSer: 1.963 ± 0.056
0.0HisThr: 0.0 ± 0.0
0.981HisVal: 0.981 ± 0.653
0.0HisTrp: 0.0 ± 0.0
1.963HisTyr: 1.963 ± 0.056
0.0HisXaa: 0.0 ± 0.0
Ile
3.925IleAla: 3.925 ± 2.613
0.0IleCys: 0.0 ± 0.0
5.888IleAsp: 5.888 ± 1.194
2.944IleGlu: 2.944 ± 0.766
2.944IlePhe: 2.944 ± 0.597
2.944IleGly: 2.944 ± 0.597
0.981IleHis: 0.981 ± 0.653
4.907IleIle: 4.907 ± 1.904
3.925IleLys: 3.925 ± 1.251
4.907IleLeu: 4.907 ± 0.541
0.981IleMet: 0.981 ± 0.71
6.869IleAsn: 6.869 ± 2.241
4.907IlePro: 4.907 ± 0.822
1.963IleGln: 1.963 ± 0.056
5.888IleArg: 5.888 ± 2.557
6.869IleSer: 6.869 ± 0.878
0.981IleThr: 0.981 ± 0.71
2.944IleVal: 2.944 ± 1.96
0.981IleTrp: 0.981 ± 0.653
2.944IleTyr: 2.944 ± 0.766
0.0IleXaa: 0.0 ± 0.0
Lys
3.925LysAla: 3.925 ± 1.251
0.0LysCys: 0.0 ± 0.0
1.963LysAsp: 1.963 ± 0.056
1.963LysGlu: 1.963 ± 1.307
3.925LysPhe: 3.925 ± 1.475
0.981LysGly: 0.981 ± 0.653
0.981LysHis: 0.981 ± 0.653
3.925LysIle: 3.925 ± 1.251
2.944LysLys: 2.944 ± 0.766
2.944LysLeu: 2.944 ± 1.96
0.0LysMet: 0.0 ± 0.0
3.925LysAsn: 3.925 ± 1.251
4.907LysPro: 4.907 ± 2.185
0.0LysGln: 0.0 ± 0.0
2.944LysArg: 2.944 ± 0.766
6.869LysSer: 6.869 ± 1.848
1.963LysThr: 1.963 ± 0.056
2.944LysVal: 2.944 ± 0.597
0.0LysTrp: 0.0 ± 0.0
5.888LysTyr: 5.888 ± 1.194
0.0LysXaa: 0.0 ± 0.0
Leu
4.907LeuAla: 4.907 ± 3.267
0.0LeuCys: 0.0 ± 0.0
3.925LeuAsp: 3.925 ± 2.838
9.814LeuGlu: 9.814 ± 2.445
1.963LeuPhe: 1.963 ± 1.307
6.869LeuGly: 6.869 ± 0.485
3.925LeuHis: 3.925 ± 1.251
7.851LeuIle: 7.851 ± 3.864
3.925LeuLys: 3.925 ± 1.475
5.888LeuLeu: 5.888 ± 2.894
0.0LeuMet: 0.0 ± 0.0
8.832LeuAsn: 8.832 ± 3.66
9.814LeuPro: 9.814 ± 1.082
2.944LeuGln: 2.944 ± 0.766
2.944LeuArg: 2.944 ± 0.597
7.851LeuSer: 7.851 ± 2.95
3.925LeuThr: 3.925 ± 0.112
2.944LeuVal: 2.944 ± 0.597
0.0LeuTrp: 0.0 ± 0.0
3.925LeuTyr: 3.925 ± 1.475
0.0LeuXaa: 0.0 ± 0.0
Met
2.944MetAla: 2.944 ± 0.766
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.981MetGlu: 0.981 ± 0.653
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
2.944MetIle: 2.944 ± 0.597
0.0MetLys: 0.0 ± 0.0
0.981MetLeu: 0.981 ± 0.653
0.0MetMet: 0.0 ± 0.0
1.963MetAsn: 1.963 ± 1.307
1.963MetPro: 1.963 ± 0.056
0.0MetGln: 0.0 ± 0.0
1.963MetArg: 1.963 ± 0.056
0.981MetSer: 0.981 ± 0.71
1.963MetThr: 1.963 ± 1.307
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
1.963MetTyr: 1.963 ± 0.056
0.0MetXaa: 0.0 ± 0.0
Asn
1.963AsnAla: 1.963 ± 0.056
0.981AsnCys: 0.981 ± 0.653
4.907AsnAsp: 4.907 ± 2.185
2.944AsnGlu: 2.944 ± 0.766
6.869AsnPhe: 6.869 ± 3.604
0.981AsnGly: 0.981 ± 0.653
1.963AsnHis: 1.963 ± 1.419
4.907AsnIle: 4.907 ± 0.822
1.963AsnLys: 1.963 ± 1.419
2.944AsnLeu: 2.944 ± 0.597
2.944AsnMet: 2.944 ± 0.597
7.851AsnAsn: 7.851 ± 4.313
2.944AsnPro: 2.944 ± 0.597
6.869AsnGln: 6.869 ± 0.878
5.888AsnArg: 5.888 ± 1.531
3.925AsnSer: 3.925 ± 1.475
3.925AsnThr: 3.925 ± 0.112
5.888AsnVal: 5.888 ± 1.194
0.0AsnTrp: 0.0 ± 0.0
4.907AsnTyr: 4.907 ± 0.822
0.0AsnXaa: 0.0 ± 0.0
Pro
4.907ProAla: 4.907 ± 0.541
0.981ProCys: 0.981 ± 0.71
1.963ProAsp: 1.963 ± 1.307
3.925ProGlu: 3.925 ± 0.112
1.963ProPhe: 1.963 ± 1.307
3.925ProGly: 3.925 ± 1.251
0.0ProHis: 0.0 ± 0.0
5.888ProIle: 5.888 ± 1.194
3.925ProLys: 3.925 ± 0.112
6.869ProLeu: 6.869 ± 3.604
0.0ProMet: 0.0 ± 0.474
1.963ProAsn: 1.963 ± 0.056
0.981ProPro: 0.981 ± 0.653
2.944ProGln: 2.944 ± 0.766
1.963ProArg: 1.963 ± 0.056
7.851ProSer: 7.851 ± 4.313
1.963ProThr: 1.963 ± 1.419
0.981ProVal: 0.981 ± 0.71
0.981ProTrp: 0.981 ± 0.653
2.944ProTyr: 2.944 ± 0.766
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
0.0GlnCys: 0.0 ± 0.0
0.981GlnAsp: 0.981 ± 0.653
1.963GlnGlu: 1.963 ± 0.056
2.944GlnPhe: 2.944 ± 0.766
3.925GlnGly: 3.925 ± 0.112
0.981GlnHis: 0.981 ± 0.71
1.963GlnIle: 1.963 ± 0.056
0.981GlnLys: 0.981 ± 0.71
1.963GlnLeu: 1.963 ± 1.419
0.981GlnMet: 0.981 ± 0.653
4.907GlnAsn: 4.907 ± 2.185
0.0GlnPro: 0.0 ± 0.0
0.0GlnGln: 0.0 ± 0.0
1.963GlnArg: 1.963 ± 1.307
0.981GlnSer: 0.981 ± 0.653
1.963GlnThr: 1.963 ± 0.056
1.963GlnVal: 1.963 ± 1.307
0.981GlnTrp: 0.981 ± 0.71
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
1.963ArgAla: 1.963 ± 0.056
0.981ArgCys: 0.981 ± 0.71
2.944ArgAsp: 2.944 ± 0.597
1.963ArgGlu: 1.963 ± 1.307
4.907ArgPhe: 4.907 ± 3.267
7.851ArgGly: 7.851 ± 4.313
0.981ArgHis: 0.981 ± 0.653
1.963ArgIle: 1.963 ± 0.056
0.0ArgLys: 0.0 ± 0.0
7.851ArgLeu: 7.851 ± 1.588
0.0ArgMet: 0.0 ± 0.0
4.907ArgAsn: 4.907 ± 1.904
0.981ArgPro: 0.981 ± 0.653
0.0ArgGln: 0.0 ± 0.0
3.925ArgArg: 3.925 ± 1.251
5.888ArgSer: 5.888 ± 1.194
3.925ArgThr: 3.925 ± 2.613
2.944ArgVal: 2.944 ± 2.129
0.0ArgTrp: 0.0 ± 0.0
0.981ArgTyr: 0.981 ± 0.71
0.0ArgXaa: 0.0 ± 0.0
Ser
0.981SerAla: 0.981 ± 0.71
1.963SerCys: 1.963 ± 0.056
3.925SerAsp: 3.925 ± 1.251
2.944SerGlu: 2.944 ± 2.129
5.888SerPhe: 5.888 ± 0.169
6.869SerGly: 6.869 ± 0.485
1.963SerHis: 1.963 ± 0.056
6.869SerIle: 6.869 ± 0.878
3.925SerLys: 3.925 ± 0.112
10.795SerLeu: 10.795 ± 0.372
1.963SerMet: 1.963 ± 0.056
2.944SerAsn: 2.944 ± 2.129
4.907SerPro: 4.907 ± 2.185
0.981SerGln: 0.981 ± 0.653
1.963SerArg: 1.963 ± 0.056
5.888SerSer: 5.888 ± 1.531
0.0SerThr: 0.0 ± 0.0
5.888SerVal: 5.888 ± 4.257
0.0SerTrp: 0.0 ± 0.0
7.851SerTyr: 7.851 ± 2.95
0.0SerXaa: 0.0 ± 0.0
Thr
0.0ThrAla: 0.0 ± 0.0
0.981ThrCys: 0.981 ± 0.653
0.0ThrAsp: 0.0 ± 0.0
0.981ThrGlu: 0.981 ± 0.71
0.981ThrPhe: 0.981 ± 0.653
3.925ThrGly: 3.925 ± 1.475
0.0ThrHis: 0.0 ± 0.0
3.925ThrIle: 3.925 ± 0.112
3.925ThrLys: 3.925 ± 0.112
2.944ThrLeu: 2.944 ± 0.766
0.0ThrMet: 0.0 ± 0.0
5.888ThrAsn: 5.888 ± 1.194
1.963ThrPro: 1.963 ± 1.307
0.0ThrGln: 0.0 ± 0.0
2.944ThrArg: 2.944 ± 0.597
3.925ThrSer: 3.925 ± 1.475
2.944ThrThr: 2.944 ± 0.597
1.963ThrVal: 1.963 ± 0.056
1.963ThrTrp: 1.963 ± 1.307
0.981ThrTyr: 0.981 ± 0.653
0.0ThrXaa: 0.0 ± 0.0
Val
2.944ValAla: 2.944 ± 2.129
0.981ValCys: 0.981 ± 0.653
3.925ValAsp: 3.925 ± 1.251
4.907ValGlu: 4.907 ± 2.185
1.963ValPhe: 1.963 ± 0.056
1.963ValGly: 1.963 ± 0.056
0.981ValHis: 0.981 ± 0.653
1.963ValIle: 1.963 ± 1.307
0.981ValLys: 0.981 ± 0.71
3.925ValLeu: 3.925 ± 1.251
1.963ValMet: 1.963 ± 0.463
1.963ValAsn: 1.963 ± 1.419
1.963ValPro: 1.963 ± 0.056
0.981ValGln: 0.981 ± 0.71
2.944ValArg: 2.944 ± 0.597
0.981ValSer: 0.981 ± 0.71
6.869ValThr: 6.869 ± 1.848
1.963ValVal: 1.963 ± 1.419
0.0ValTrp: 0.0 ± 0.0
3.925ValTyr: 3.925 ± 2.613
0.0ValXaa: 0.0 ± 0.0
Trp
0.981TrpAla: 0.981 ± 0.71
0.0TrpCys: 0.0 ± 0.0
0.981TrpAsp: 0.981 ± 0.653
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.981TrpGly: 0.981 ± 0.653
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.963TrpLeu: 1.963 ± 1.307
0.0TrpMet: 0.0 ± 0.0
0.981TrpAsn: 0.981 ± 0.71
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.981TrpArg: 0.981 ± 0.71
2.944TrpSer: 2.944 ± 0.766
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.944TyrAla: 2.944 ± 0.766
0.981TyrCys: 0.981 ± 0.653
6.869TyrAsp: 6.869 ± 0.485
0.981TyrGlu: 0.981 ± 0.71
3.925TyrPhe: 3.925 ± 1.251
0.981TyrGly: 0.981 ± 0.653
0.981TyrHis: 0.981 ± 0.71
1.963TyrIle: 1.963 ± 0.056
1.963TyrLys: 1.963 ± 1.307
7.851TyrLeu: 7.851 ± 1.588
1.963TyrMet: 1.963 ± 0.056
2.944TyrAsn: 2.944 ± 0.766
3.925TyrPro: 3.925 ± 0.112
2.944TyrGln: 2.944 ± 0.597
3.925TyrArg: 3.925 ± 1.475
4.907TyrSer: 4.907 ± 0.541
1.963TyrThr: 1.963 ± 1.419
2.944TyrVal: 2.944 ± 1.96
0.0TyrTrp: 0.0 ± 0.0
1.963TyrTyr: 1.963 ± 1.419
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1020 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski