Amino acid dipepetide frequency for Anaerobacterium chartisolvens

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.914AlaAla: 6.914 ± 0.092	0.958AlaCys: 0.958 ± 0.027	3.828AlaAsp: 3.828 ± 0.061	4.794AlaGlu: 4.794 ± 0.066	3.139AlaPhe: 3.139 ± 0.055	6.177AlaGly: 6.177 ± 0.086	1.051AlaHis: 1.051 ± 0.029	5.197AlaIle: 5.197 ± 0.071	4.116AlaLys: 4.116 ± 0.055	6.71AlaLeu: 6.71 ± 0.078	1.932AlaMet: 1.932 ± 0.041	2.516AlaAsn: 2.516 ± 0.046	1.931AlaPro: 1.931 ± 0.036	2.056AlaGln: 2.056 ± 0.036	3.193AlaArg: 3.193 ± 0.057	4.783AlaSer: 4.783 ± 0.074	2.868AlaThr: 2.868 ± 0.11	6.348AlaVal: 6.348 ± 0.073	0.577AlaTrp: 0.577 ± 0.024	2.686AlaTyr: 2.686 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.865CysAla: 0.865 ± 0.024	0.286CysCys: 0.286 ± 0.016	0.744CysAsp: 0.744 ± 0.024	0.86CysGlu: 0.86 ± 0.025	0.617CysPhe: 0.617 ± 0.022	1.341CysGly: 1.341 ± 0.038	0.263CysHis: 0.263 ± 0.014	1.165CysIle: 1.165 ± 0.03	0.791CysLys: 0.791 ± 0.027	1.033CysLeu: 1.033 ± 0.029	0.377CysMet: 0.377 ± 0.016	0.565CysAsn: 0.565 ± 0.021	0.563CysPro: 0.563 ± 0.026	0.293CysGln: 0.293 ± 0.016	0.722CysArg: 0.722 ± 0.024	0.97CysSer: 0.97 ± 0.031	0.672CysThr: 0.672 ± 0.023	0.782CysVal: 0.782 ± 0.023	0.129CysTrp: 0.129 ± 0.01	0.457CysTyr: 0.457 ± 0.019	0.0CysXaa: 0.0 ± 0.0
Asp	3.677AspAla: 3.677 ± 0.061	0.733AspCys: 0.733 ± 0.024	2.581AspAsp: 2.581 ± 0.048	3.963AspGlu: 3.963 ± 0.058	2.756AspPhe: 2.756 ± 0.043	4.26AspGly: 4.26 ± 0.088	0.587AspHis: 0.587 ± 0.024	5.824AspIle: 5.824 ± 0.072	3.97AspLys: 3.97 ± 0.056	4.139AspLeu: 4.139 ± 0.065	1.808AspMet: 1.808 ± 0.04	2.672AspAsn: 2.672 ± 0.042	1.721AspPro: 1.721 ± 0.043	0.983AspGln: 0.983 ± 0.028	2.616AspArg: 2.616 ± 0.042	3.764AspSer: 3.764 ± 0.062	2.779AspThr: 2.779 ± 0.052	3.518AspVal: 3.518 ± 0.054	0.609AspTrp: 0.609 ± 0.025	2.448AspTyr: 2.448 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	5.354GluAla: 5.354 ± 0.073	0.746GluCys: 0.746 ± 0.024	3.761GluAsp: 3.761 ± 0.059	5.425GluGlu: 5.425 ± 0.079	2.62GluPhe: 2.62 ± 0.042	4.606GluGly: 4.606 ± 0.06	1.046GluHis: 1.046 ± 0.028	5.956GluIle: 5.956 ± 0.075	5.594GluLys: 5.594 ± 0.079	6.629GluLeu: 6.629 ± 0.086	1.979GluMet: 1.979 ± 0.037	3.749GluAsn: 3.749 ± 0.061	1.685GluPro: 1.685 ± 0.033	2.247GluGln: 2.247 ± 0.047	3.334GluArg: 3.334 ± 0.059	3.586GluSer: 3.586 ± 0.047	2.801GluThr: 2.801 ± 0.051	4.304GluVal: 4.304 ± 0.063	0.656GluTrp: 0.656 ± 0.025	3.003GluTyr: 3.003 ± 0.057	0.0GluXaa: 0.0 ± 0.0
Phe	2.807PheAla: 2.807 ± 0.048	0.62PheCys: 0.62 ± 0.02	2.625PheAsp: 2.625 ± 0.054	2.777PheGlu: 2.777 ± 0.052	1.923PhePhe: 1.923 ± 0.048	2.874PheGly: 2.874 ± 0.05	0.634PheHis: 0.634 ± 0.023	3.791PheIle: 3.791 ± 0.074	2.974PheLys: 2.974 ± 0.047	3.513PheLeu: 3.513 ± 0.064	1.183PheMet: 1.183 ± 0.029	2.303PheAsn: 2.303 ± 0.039	1.4PhePro: 1.4 ± 0.037	0.981PheGln: 0.981 ± 0.027	1.606PheArg: 1.606 ± 0.034	3.298PheSer: 3.298 ± 0.059	2.271PheThr: 2.271 ± 0.043	2.535PheVal: 2.535 ± 0.052	0.394PheTrp: 0.394 ± 0.019	1.701PheTyr: 1.701 ± 0.041	0.0PheXaa: 0.0 ± 0.0
Gly	5.073GlyAla: 5.073 ± 0.126	1.157GlyCys: 1.157 ± 0.038	3.749GlyAsp: 3.749 ± 0.053	4.852GlyGlu: 4.852 ± 0.07	3.233GlyPhe: 3.233 ± 0.056	5.436GlyGly: 5.436 ± 0.107	1.26GlyHis: 1.26 ± 0.029	7.053GlyIle: 7.053 ± 0.084	5.201GlyLys: 5.201 ± 0.068	6.123GlyLeu: 6.123 ± 0.07	2.315GlyMet: 2.315 ± 0.05	3.341GlyAsn: 3.341 ± 0.081	1.492GlyPro: 1.492 ± 0.033	2.042GlyGln: 2.042 ± 0.043	3.564GlyArg: 3.564 ± 0.061	4.856GlySer: 4.856 ± 0.085	4.193GlyThr: 4.193 ± 0.089	4.882GlyVal: 4.882 ± 0.065	0.702GlyTrp: 0.702 ± 0.024	3.259GlyTyr: 3.259 ± 0.065	0.0GlyXaa: 0.0 ± 0.0
His	0.886HisAla: 0.886 ± 0.026	0.275HisCys: 0.275 ± 0.015	0.828HisAsp: 0.828 ± 0.024	0.949HisGlu: 0.949 ± 0.024	0.745HisPhe: 0.745 ± 0.025	1.186HisGly: 1.186 ± 0.029	0.337HisHis: 0.337 ± 0.016	1.392HisIle: 1.392 ± 0.036	0.971HisLys: 0.971 ± 0.023	1.263HisLeu: 1.263 ± 0.032	0.477HisMet: 0.477 ± 0.019	0.812HisAsn: 0.812 ± 0.026	0.696HisPro: 0.696 ± 0.021	0.41HisGln: 0.41 ± 0.019	0.735HisArg: 0.735 ± 0.025	1.117HisSer: 1.117 ± 0.029	0.866HisThr: 0.866 ± 0.036	0.91HisVal: 0.91 ± 0.024	0.175HisTrp: 0.175 ± 0.01	0.633HisTyr: 0.633 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	6.082IleAla: 6.082 ± 0.061	1.198IleCys: 1.198 ± 0.032	5.133IleAsp: 5.133 ± 0.063	5.712IleGlu: 5.712 ± 0.07	3.437IlePhe: 3.437 ± 0.066	5.29IleGly: 5.29 ± 0.077	1.212IleHis: 1.212 ± 0.031	6.949IleIle: 6.949 ± 0.091	6.091IleLys: 6.091 ± 0.073	7.125IleLeu: 7.125 ± 0.093	2.093IleMet: 2.093 ± 0.043	4.539IleAsn: 4.539 ± 0.067	3.365IlePro: 3.365 ± 0.049	2.212IleGln: 2.212 ± 0.04	3.623IleArg: 3.623 ± 0.054	6.499IleSer: 6.499 ± 0.073	4.387IleThr: 4.387 ± 0.057	5.084IleVal: 5.084 ± 0.06	0.635IleTrp: 0.635 ± 0.021	3.036IleTyr: 3.036 ± 0.056	0.0IleXaa: 0.0 ± 0.0
Lys	5.225LysAla: 5.225 ± 0.062	0.73LysCys: 0.73 ± 0.025	4.025LysAsp: 4.025 ± 0.061	5.541LysGlu: 5.541 ± 0.085	2.13LysPhe: 2.13 ± 0.041	4.827LysGly: 4.827 ± 0.06	1.125LysHis: 1.125 ± 0.027	5.55LysIle: 5.55 ± 0.062	5.595LysLys: 5.595 ± 0.081	5.795LysLeu: 5.795 ± 0.074	2.008LysMet: 2.008 ± 0.039	3.948LysAsn: 3.948 ± 0.067	2.181LysPro: 2.181 ± 0.046	2.178LysGln: 2.178 ± 0.045	3.34LysArg: 3.34 ± 0.049	4.457LysSer: 4.457 ± 0.067	3.492LysThr: 3.492 ± 0.057	4.16LysVal: 4.16 ± 0.062	0.643LysTrp: 0.643 ± 0.022	3.05LysTyr: 3.05 ± 0.055	0.0LysXaa: 0.0 ± 0.0
Leu	6.063LeuAla: 6.063 ± 0.072	1.33LeuCys: 1.33 ± 0.032	4.759LeuAsp: 4.759 ± 0.068	5.993LeuGlu: 5.993 ± 0.076	3.707LeuPhe: 3.707 ± 0.083	6.066LeuGly: 6.066 ± 0.082	1.354LeuHis: 1.354 ± 0.029	6.608LeuIle: 6.608 ± 0.091	7.365LeuLys: 7.365 ± 0.097	8.09LeuLeu: 8.09 ± 0.103	2.516LeuMet: 2.516 ± 0.041	4.403LeuAsn: 4.403 ± 0.064	3.389LeuPro: 3.389 ± 0.059	2.436LeuGln: 2.436 ± 0.038	3.698LeuArg: 3.698 ± 0.056	6.875LeuSer: 6.875 ± 0.071	4.39LeuThr: 4.39 ± 0.062	5.112LeuVal: 5.112 ± 0.066	0.784LeuTrp: 0.784 ± 0.024	3.122LeuTyr: 3.122 ± 0.054	0.0LeuXaa: 0.0 ± 0.0
Met	2.146MetAla: 2.146 ± 0.044	0.301MetCys: 0.301 ± 0.015	1.712MetAsp: 1.712 ± 0.037	2.074MetGlu: 2.074 ± 0.047	1.019MetPhe: 1.019 ± 0.03	2.2MetGly: 2.2 ± 0.046	0.461MetHis: 0.461 ± 0.021	1.798MetIle: 1.798 ± 0.038	2.146MetLys: 2.146 ± 0.044	2.915MetLeu: 2.915 ± 0.045	0.682MetMet: 0.682 ± 0.021	1.381MetAsn: 1.381 ± 0.031	1.206MetPro: 1.206 ± 0.036	0.882MetGln: 0.882 ± 0.025	1.25MetArg: 1.25 ± 0.03	1.854MetSer: 1.854 ± 0.034	1.248MetThr: 1.248 ± 0.03	1.782MetVal: 1.782 ± 0.035	0.185MetTrp: 0.185 ± 0.012	0.859MetTyr: 0.859 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	3.367AsnAla: 3.367 ± 0.054	0.593AsnCys: 0.593 ± 0.02	2.423AsnAsp: 2.423 ± 0.042	3.153AsnGlu: 3.153 ± 0.049	1.787AsnPhe: 1.787 ± 0.037	3.728AsnGly: 3.728 ± 0.075	0.642AsnHis: 0.642 ± 0.023	4.815AsnIle: 4.815 ± 0.079	3.324AsnLys: 3.324 ± 0.053	3.724AsnLeu: 3.724 ± 0.053	1.395AsnMet: 1.395 ± 0.034	2.535AsnAsn: 2.535 ± 0.048	2.08AsnPro: 2.08 ± 0.036	1.181AsnGln: 1.181 ± 0.032	2.059AsnArg: 2.059 ± 0.044	3.412AsnSer: 3.412 ± 0.058	2.744AsnThr: 2.744 ± 0.061	3.086AsnVal: 3.086 ± 0.052	0.51AsnTrp: 0.51 ± 0.018	1.911AsnTyr: 1.911 ± 0.04	0.0AsnXaa: 0.0 ± 0.0
Pro	2.365ProAla: 2.365 ± 0.049	0.476ProCys: 0.476 ± 0.02	2.294ProAsp: 2.294 ± 0.039	2.95ProGlu: 2.95 ± 0.048	1.495ProPhe: 1.495 ± 0.042	2.66ProGly: 2.66 ± 0.051	0.661ProHis: 0.661 ± 0.02	2.205ProIle: 2.205 ± 0.041	1.771ProLys: 1.771 ± 0.038	2.824ProLeu: 2.824 ± 0.054	0.8ProMet: 0.8 ± 0.023	1.271ProAsn: 1.271 ± 0.035	1.028ProPro: 1.028 ± 0.032	1.186ProGln: 1.186 ± 0.026	1.137ProArg: 1.137 ± 0.031	2.246ProSer: 2.246 ± 0.044	1.382ProThr: 1.382 ± 0.031	2.936ProVal: 2.936 ± 0.053	0.336ProTrp: 0.336 ± 0.016	1.374ProTyr: 1.374 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	2.023GlnAla: 2.023 ± 0.038	0.305GlnCys: 0.305 ± 0.014	1.343GlnAsp: 1.343 ± 0.028	1.804GlnGlu: 1.804 ± 0.038	1.002GlnPhe: 1.002 ± 0.024	1.845GlnGly: 1.845 ± 0.04	0.454GlnHis: 0.454 ± 0.02	2.285GlnIle: 2.285 ± 0.041	2.329GlnLys: 2.329 ± 0.038	2.503GlnLeu: 2.503 ± 0.051	0.928GlnMet: 0.928 ± 0.028	1.465GlnAsn: 1.465 ± 0.035	0.918GlnPro: 0.918 ± 0.027	1.112GlnGln: 1.112 ± 0.037	1.481GlnArg: 1.481 ± 0.03	1.872GlnSer: 1.872 ± 0.033	1.357GlnThr: 1.357 ± 0.035	1.706GlnVal: 1.706 ± 0.041	0.315GlnTrp: 0.315 ± 0.017	1.273GlnTyr: 1.273 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	2.904ArgAla: 2.904 ± 0.056	0.523ArgCys: 0.523 ± 0.02	2.539ArgAsp: 2.539 ± 0.049	3.529ArgGlu: 3.529 ± 0.064	1.902ArgPhe: 1.902 ± 0.035	2.726ArgGly: 2.726 ± 0.046	0.895ArgHis: 0.895 ± 0.029	3.919ArgIle: 3.919 ± 0.057	3.015ArgLys: 3.015 ± 0.051	4.738ArgLeu: 4.738 ± 0.077	1.296ArgMet: 1.296 ± 0.033	2.047ArgAsn: 2.047 ± 0.033	1.368ArgPro: 1.368 ± 0.032	1.569ArgGln: 1.569 ± 0.032	2.089ArgArg: 2.089 ± 0.044	2.371ArgSer: 2.371 ± 0.042	2.003ArgThr: 2.003 ± 0.041	3.034ArgVal: 3.034 ± 0.052	0.423ArgTrp: 0.423 ± 0.017	1.993ArgTyr: 1.993 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	4.516SerAla: 4.516 ± 0.07	0.902SerCys: 0.902 ± 0.027	3.608SerAsp: 3.608 ± 0.055	4.307SerGlu: 4.307 ± 0.054	3.303SerPhe: 3.303 ± 0.048	5.964SerGly: 5.964 ± 0.087	1.108SerHis: 1.108 ± 0.03	5.873SerIle: 5.873 ± 0.071	4.239SerLys: 4.239 ± 0.06	6.15SerLeu: 6.15 ± 0.072	1.898SerMet: 1.898 ± 0.04	2.924SerAsn: 2.924 ± 0.051	2.291SerPro: 2.291 ± 0.041	2.055SerGln: 2.055 ± 0.036	3.285SerArg: 3.285 ± 0.046	5.015SerSer: 5.015 ± 0.08	3.162SerThr: 3.162 ± 0.064	4.867SerVal: 4.867 ± 0.062	0.626SerTrp: 0.626 ± 0.024	2.556SerTyr: 2.556 ± 0.063	0.0SerXaa: 0.0 ± 0.0
Thr	4.145ThrAla: 4.145 ± 0.071	0.567ThrCys: 0.567 ± 0.02	2.822ThrAsp: 2.822 ± 0.059	3.113ThrGlu: 3.113 ± 0.048	1.929ThrPhe: 1.929 ± 0.039	5.008ThrGly: 5.008 ± 0.176	0.812ThrHis: 0.812 ± 0.024	3.645ThrIle: 3.645 ± 0.058	2.443ThrLys: 2.443 ± 0.044	4.275ThrLeu: 4.275 ± 0.065	1.144ThrMet: 1.144 ± 0.03	1.884ThrAsn: 1.884 ± 0.039	2.051ThrPro: 2.051 ± 0.043	1.337ThrGln: 1.337 ± 0.036	1.928ThrArg: 1.928 ± 0.044	3.087ThrSer: 3.087 ± 0.067	2.349ThrThr: 2.349 ± 0.066	4.202ThrVal: 4.202 ± 0.081	0.488ThrTrp: 0.488 ± 0.033	1.916ThrTyr: 1.916 ± 0.058	0.0ThrXaa: 0.0 ± 0.0
Val	4.341ValAla: 4.341 ± 0.064	1.023ValCys: 1.023 ± 0.025	3.635ValAsp: 3.635 ± 0.051	4.234ValGlu: 4.234 ± 0.065	3.19ValPhe: 3.19 ± 0.053	3.981ValGly: 3.981 ± 0.06	0.977ValHis: 0.977 ± 0.029	5.611ValIle: 5.611 ± 0.072	4.828ValLys: 4.828 ± 0.06	6.327ValLeu: 6.327 ± 0.077	1.918ValMet: 1.918 ± 0.038	3.354ValAsn: 3.354 ± 0.066	2.344ValPro: 2.344 ± 0.045	1.79ValGln: 1.79 ± 0.037	2.883ValArg: 2.883 ± 0.047	5.0ValSer: 5.0 ± 0.065	3.471ValThr: 3.471 ± 0.075	4.432ValVal: 4.432 ± 0.067	0.63ValTrp: 0.63 ± 0.024	2.595ValTyr: 2.595 ± 0.051	0.0ValXaa: 0.0 ± 0.0
Trp	0.587TrpAla: 0.587 ± 0.021	0.138TrpCys: 0.138 ± 0.011	0.625TrpAsp: 0.625 ± 0.024	0.661TrpGlu: 0.661 ± 0.022	0.398TrpPhe: 0.398 ± 0.018	0.705TrpGly: 0.705 ± 0.029	0.163TrpHis: 0.163 ± 0.011	0.621TrpIle: 0.621 ± 0.022	0.605TrpLys: 0.605 ± 0.023	0.852TrpLeu: 0.852 ± 0.026	0.268TrpMet: 0.268 ± 0.013	0.503TrpAsn: 0.503 ± 0.02	0.241TrpPro: 0.241 ± 0.014	0.357TrpGln: 0.357 ± 0.015	0.405TrpArg: 0.405 ± 0.015	0.666TrpSer: 0.666 ± 0.033	0.5TrpThr: 0.5 ± 0.035	0.567TrpVal: 0.567 ± 0.018	0.124TrpTrp: 0.124 ± 0.009	0.347TrpTyr: 0.347 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.439TyrAla: 2.439 ± 0.046	0.635TyrCys: 0.635 ± 0.021	2.373TyrAsp: 2.373 ± 0.107	2.389TyrGlu: 2.389 ± 0.046	1.88TyrPhe: 1.88 ± 0.039	2.902TyrGly: 2.902 ± 0.054	0.621TyrHis: 0.621 ± 0.023	3.443TyrIle: 3.443 ± 0.051	2.634TyrLys: 2.634 ± 0.05	3.33TyrLeu: 3.33 ± 0.051	1.081TyrMet: 1.081 ± 0.025	2.262TyrAsn: 2.262 ± 0.057	1.446TyrPro: 1.446 ± 0.032	1.01TyrGln: 1.01 ± 0.027	1.936TyrArg: 1.936 ± 0.044	2.921TyrSer: 2.921 ± 0.055	2.21TyrThr: 2.21 ± 0.056	2.314TyrVal: 2.314 ± 0.039	0.392TyrTrp: 0.392 ± 0.017	1.744TyrTyr: 1.744 ± 0.045	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4253 proteins (1430626 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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