Amino acid dipepetide frequency for Parabacteroides gordonii MS-1 = DSM 23371

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.686AlaAla: 5.686 ± 0.075	0.911AlaCys: 0.911 ± 0.024	4.363AlaAsp: 4.363 ± 0.052	4.561AlaGlu: 4.561 ± 0.061	3.175AlaPhe: 3.175 ± 0.036	5.508AlaGly: 5.508 ± 0.071	1.016AlaHis: 1.016 ± 0.025	4.605AlaIle: 4.605 ± 0.059	3.885AlaLys: 3.885 ± 0.05	6.384AlaLeu: 6.384 ± 0.069	1.732AlaMet: 1.732 ± 0.033	3.392AlaAsn: 3.392 ± 0.058	2.346AlaPro: 2.346 ± 0.043	2.299AlaGln: 2.299 ± 0.038	2.903AlaArg: 2.903 ± 0.043	4.429AlaSer: 4.429 ± 0.057	4.187AlaThr: 4.187 ± 0.058	4.578AlaVal: 4.578 ± 0.048	0.843AlaTrp: 0.843 ± 0.023	2.936AlaTyr: 2.936 ± 0.041	0.0AlaXaa: 0.0 ± 0.0
Cys	0.616CysAla: 0.616 ± 0.019	0.2CysCys: 0.2 ± 0.01	0.574CysAsp: 0.574 ± 0.02	0.579CysGlu: 0.579 ± 0.02	0.587CysPhe: 0.587 ± 0.019	0.872CysGly: 0.872 ± 0.021	0.255CysHis: 0.255 ± 0.013	0.841CysIle: 0.841 ± 0.02	0.613CysLys: 0.613 ± 0.019	1.083CysLeu: 1.083 ± 0.025	0.316CysMet: 0.316 ± 0.012	0.55CysAsn: 0.55 ± 0.016	0.472CysPro: 0.472 ± 0.018	0.282CysGln: 0.282 ± 0.012	0.574CysArg: 0.574 ± 0.019	0.761CysSer: 0.761 ± 0.023	0.647CysThr: 0.647 ± 0.019	0.614CysVal: 0.614 ± 0.019	0.151CysTrp: 0.151 ± 0.009	0.516CysTyr: 0.516 ± 0.019	0.0CysXaa: 0.0 ± 0.0
Asp	3.988AspAla: 3.988 ± 0.055	0.56AspCys: 0.56 ± 0.019	2.728AspAsp: 2.728 ± 0.045	3.613AspGlu: 3.613 ± 0.052	2.922AspPhe: 2.922 ± 0.039	4.511AspGly: 4.511 ± 0.061	0.849AspHis: 0.849 ± 0.021	4.269AspIle: 4.269 ± 0.049	4.248AspLys: 4.248 ± 0.048	4.881AspLeu: 4.881 ± 0.059	1.61AspMet: 1.61 ± 0.032	3.129AspAsn: 3.129 ± 0.049	2.313AspPro: 2.313 ± 0.036	1.562AspGln: 1.562 ± 0.027	2.562AspArg: 2.562 ± 0.042	2.95AspSer: 2.95 ± 0.045	2.751AspThr: 2.751 ± 0.036	3.516AspVal: 3.516 ± 0.046	0.954AspTrp: 0.954 ± 0.022	2.915AspTyr: 2.915 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	4.792GluAla: 4.792 ± 0.066	0.554GluCys: 0.554 ± 0.017	3.262GluAsp: 3.262 ± 0.047	4.895GluGlu: 4.895 ± 0.064	2.233GluPhe: 2.233 ± 0.035	4.177GluGly: 4.177 ± 0.052	1.089GluHis: 1.089 ± 0.025	4.561GluIle: 4.561 ± 0.048	5.084GluLys: 5.084 ± 0.054	6.026GluLeu: 6.026 ± 0.069	1.94GluMet: 1.94 ± 0.032	3.714GluAsn: 3.714 ± 0.05	1.835GluPro: 1.835 ± 0.032	2.601GluGln: 2.601 ± 0.044	2.953GluArg: 2.953 ± 0.05	3.342GluSer: 3.342 ± 0.041	3.552GluThr: 3.552 ± 0.041	4.382GluVal: 4.382 ± 0.05	0.852GluTrp: 0.852 ± 0.021	2.744GluTyr: 2.744 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	2.914PheAla: 2.914 ± 0.04	0.584PheCys: 0.584 ± 0.019	2.899PheAsp: 2.899 ± 0.038	2.46PheGlu: 2.46 ± 0.038	2.189PhePhe: 2.189 ± 0.049	3.134PheGly: 3.134 ± 0.045	0.79PheHis: 0.79 ± 0.02	3.152PheIle: 3.152 ± 0.054	2.403PheLys: 2.403 ± 0.041	4.023PheLeu: 4.023 ± 0.056	1.211PheMet: 1.211 ± 0.024	2.542PheAsn: 2.542 ± 0.041	1.723PhePro: 1.723 ± 0.03	1.233PheGln: 1.233 ± 0.024	2.198PheArg: 2.198 ± 0.041	3.511PheSer: 3.511 ± 0.048	3.067PheThr: 3.067 ± 0.035	2.762PheVal: 2.762 ± 0.034	0.587PheTrp: 0.587 ± 0.018	2.008PheTyr: 2.008 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	4.365GlyAla: 4.365 ± 0.052	0.879GlyCys: 0.879 ± 0.021	3.752GlyAsp: 3.752 ± 0.053	4.384GlyGlu: 4.384 ± 0.046	3.192GlyPhe: 3.192 ± 0.042	4.903GlyGly: 4.903 ± 0.075	1.115GlyHis: 1.115 ± 0.024	5.114GlyIle: 5.114 ± 0.063	5.389GlyLys: 5.389 ± 0.055	5.842GlyLeu: 5.842 ± 0.061	2.013GlyMet: 2.013 ± 0.034	3.847GlyAsn: 3.847 ± 0.056	1.295GlyPro: 1.295 ± 0.029	2.186GlyGln: 2.186 ± 0.034	2.814GlyArg: 2.814 ± 0.04	4.426GlySer: 4.426 ± 0.06	4.597GlyThr: 4.597 ± 0.073	4.658GlyVal: 4.658 ± 0.056	1.082GlyTrp: 1.082 ± 0.025	3.517GlyTyr: 3.517 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	1.035HisAla: 1.035 ± 0.021	0.242HisCys: 0.242 ± 0.011	0.815HisAsp: 0.815 ± 0.023	0.941HisGlu: 0.941 ± 0.023	0.913HisPhe: 0.913 ± 0.024	1.032HisGly: 1.032 ± 0.027	0.391HisHis: 0.391 ± 0.016	1.317HisIle: 1.317 ± 0.026	0.919HisLys: 0.919 ± 0.022	1.694HisLeu: 1.694 ± 0.033	0.333HisMet: 0.333 ± 0.013	0.873HisAsn: 0.873 ± 0.024	0.929HisPro: 0.929 ± 0.023	0.544HisGln: 0.544 ± 0.017	0.767HisArg: 0.767 ± 0.021	1.079HisSer: 1.079 ± 0.026	0.974HisThr: 0.974 ± 0.025	0.952HisVal: 0.952 ± 0.024	0.252HisTrp: 0.252 ± 0.012	0.843HisTyr: 0.843 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	5.015IleAla: 5.015 ± 0.072	0.885IleCys: 0.885 ± 0.021	4.099IleAsp: 4.099 ± 0.049	4.386IleGlu: 4.386 ± 0.05	2.606IlePhe: 2.606 ± 0.042	4.602IleGly: 4.602 ± 0.062	1.244IleHis: 1.244 ± 0.028	4.279IleIle: 4.279 ± 0.064	4.085IleLys: 4.085 ± 0.047	5.833IleLeu: 5.833 ± 0.062	1.433IleMet: 1.433 ± 0.029	3.574IleAsn: 3.574 ± 0.052	3.216IlePro: 3.216 ± 0.038	2.338IleGln: 2.338 ± 0.034	3.563IleArg: 3.563 ± 0.055	4.846IleSer: 4.846 ± 0.052	4.381IleThr: 4.381 ± 0.055	4.176IleVal: 4.176 ± 0.044	0.709IleTrp: 0.709 ± 0.02	2.791IleTyr: 2.791 ± 0.038	0.0IleXaa: 0.0 ± 0.0
Lys	4.784LysAla: 4.784 ± 0.061	0.469LysCys: 0.469 ± 0.017	4.267LysAsp: 4.267 ± 0.05	5.805LysGlu: 5.805 ± 0.062	2.084LysPhe: 2.084 ± 0.033	4.514LysGly: 4.514 ± 0.054	1.1LysHis: 1.1 ± 0.024	4.148LysIle: 4.148 ± 0.046	4.829LysLys: 4.829 ± 0.054	5.208LysLeu: 5.208 ± 0.051	1.92LysMet: 1.92 ± 0.028	3.533LysAsn: 3.533 ± 0.043	2.218LysPro: 2.218 ± 0.04	2.625LysGln: 2.625 ± 0.034	2.924LysArg: 2.924 ± 0.043	3.459LysSer: 3.459 ± 0.041	3.688LysThr: 3.688 ± 0.042	4.372LysVal: 4.372 ± 0.051	0.759LysTrp: 0.759 ± 0.02	2.912LysTyr: 2.912 ± 0.041	0.0LysXaa: 0.0 ± 0.0
Leu	6.242LeuAla: 6.242 ± 0.057	1.221LeuCys: 1.221 ± 0.03	4.831LeuAsp: 4.831 ± 0.054	4.916LeuGlu: 4.916 ± 0.054	4.704LeuPhe: 4.704 ± 0.062	5.401LeuGly: 5.401 ± 0.064	1.586LeuHis: 1.586 ± 0.029	5.537LeuIle: 5.537 ± 0.068	6.291LeuLys: 6.291 ± 0.06	9.318LeuLeu: 9.318 ± 0.092	2.248LeuMet: 2.248 ± 0.04	4.849LeuAsn: 4.849 ± 0.058	4.189LeuPro: 4.189 ± 0.052	3.292LeuGln: 3.292 ± 0.047	3.928LeuArg: 3.928 ± 0.053	7.07LeuSer: 7.07 ± 0.066	5.594LeuThr: 5.594 ± 0.053	5.163LeuVal: 5.163 ± 0.053	1.024LeuTrp: 1.024 ± 0.026	3.795LeuTyr: 3.795 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	1.884MetAla: 1.884 ± 0.033	0.206MetCys: 0.206 ± 0.01	1.479MetAsp: 1.479 ± 0.027	1.796MetGlu: 1.796 ± 0.033	0.956MetPhe: 0.956 ± 0.021	1.645MetGly: 1.645 ± 0.029	0.389MetHis: 0.389 ± 0.014	1.62MetIle: 1.62 ± 0.031	2.405MetLys: 2.405 ± 0.034	2.336MetLeu: 2.336 ± 0.034	0.688MetMet: 0.688 ± 0.024	1.577MetAsn: 1.577 ± 0.026	1.111MetPro: 1.111 ± 0.024	1.061MetGln: 1.061 ± 0.023	1.137MetArg: 1.137 ± 0.022	1.401MetSer: 1.401 ± 0.026	1.391MetThr: 1.391 ± 0.026	1.501MetVal: 1.501 ± 0.031	0.245MetTrp: 0.245 ± 0.012	0.882MetTyr: 0.882 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.482AsnAla: 3.482 ± 0.051	0.504AsnCys: 0.504 ± 0.02	2.769AsnAsp: 2.769 ± 0.042	3.175AsnGlu: 3.175 ± 0.039	2.216AsnPhe: 2.216 ± 0.037	4.169AsnGly: 4.169 ± 0.065	0.919AsnHis: 0.919 ± 0.021	3.916AsnIle: 3.916 ± 0.049	3.463AsnLys: 3.463 ± 0.047	4.503AsnLeu: 4.503 ± 0.053	1.388AsnMet: 1.388 ± 0.024	2.962AsnAsn: 2.962 ± 0.046	2.71AsnPro: 2.71 ± 0.033	1.761AsnGln: 1.761 ± 0.036	2.504AsnArg: 2.504 ± 0.04	3.074AsnSer: 3.074 ± 0.04	3.137AsnThr: 3.137 ± 0.05	3.17AsnVal: 3.17 ± 0.05	0.704AsnTrp: 0.704 ± 0.022	2.543AsnTyr: 2.543 ± 0.041	0.0AsnXaa: 0.0 ± 0.0
Pro	3.008ProAla: 3.008 ± 0.044	0.333ProCys: 0.333 ± 0.013	2.867ProAsp: 2.867 ± 0.042	3.591ProGlu: 3.591 ± 0.051	1.885ProPhe: 1.885 ± 0.032	2.747ProGly: 2.747 ± 0.038	0.624ProHis: 0.624 ± 0.017	2.232ProIle: 2.232 ± 0.034	1.906ProLys: 1.906 ± 0.034	3.296ProLeu: 3.296 ± 0.041	0.851ProMet: 0.851 ± 0.022	1.667ProAsn: 1.667 ± 0.027	0.842ProPro: 0.842 ± 0.024	1.3ProGln: 1.3 ± 0.025	1.265ProArg: 1.265 ± 0.027	2.454ProSer: 2.454 ± 0.034	2.01ProThr: 2.01 ± 0.035	3.462ProVal: 3.462 ± 0.039	0.496ProTrp: 0.496 ± 0.016	1.702ProTyr: 1.702 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	2.514GlnAla: 2.514 ± 0.042	0.28GlnCys: 0.28 ± 0.015	1.638GlnAsp: 1.638 ± 0.033	2.262GlnGlu: 2.262 ± 0.038	1.331GlnPhe: 1.331 ± 0.025	2.022GlnGly: 2.022 ± 0.032	0.561GlnHis: 0.561 ± 0.016	2.352GlnIle: 2.352 ± 0.031	2.378GlnLys: 2.378 ± 0.031	3.314GlnLeu: 3.314 ± 0.048	0.93GlnMet: 0.93 ± 0.021	1.765GlnAsn: 1.765 ± 0.032	1.354GlnPro: 1.354 ± 0.026	1.633GlnGln: 1.633 ± 0.032	1.481GlnArg: 1.481 ± 0.027	2.068GlnSer: 2.068 ± 0.034	2.185GlnThr: 2.185 ± 0.033	2.177GlnVal: 2.177 ± 0.032	0.499GlnTrp: 0.499 ± 0.018	1.498GlnTyr: 1.498 ± 0.032	0.0GlnXaa: 0.0 ± 0.0
Arg	2.622ArgAla: 2.622 ± 0.043	0.424ArgCys: 0.424 ± 0.015	2.087ArgAsp: 2.087 ± 0.04	2.948ArgGlu: 2.948 ± 0.036	2.317ArgPhe: 2.317 ± 0.038	2.284ArgGly: 2.284 ± 0.036	0.844ArgHis: 0.844 ± 0.024	3.526ArgIle: 3.526 ± 0.045	3.218ArgLys: 3.218 ± 0.042	4.459ArgLeu: 4.459 ± 0.062	1.433ArgMet: 1.433 ± 0.031	2.44ArgAsn: 2.44 ± 0.035	1.585ArgPro: 1.585 ± 0.035	1.732ArgGln: 1.732 ± 0.035	2.046ArgArg: 2.046 ± 0.043	2.419ArgSer: 2.419 ± 0.037	2.417ArgThr: 2.417 ± 0.036	2.514ArgVal: 2.514 ± 0.034	0.625ArgTrp: 0.625 ± 0.019	2.263ArgTyr: 2.263 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	4.181SerAla: 4.181 ± 0.056	0.794SerCys: 0.794 ± 0.02	3.663SerAsp: 3.663 ± 0.04	3.601SerGlu: 3.601 ± 0.042	3.567SerPhe: 3.567 ± 0.047	5.066SerGly: 5.066 ± 0.061	1.045SerHis: 1.045 ± 0.027	4.337SerIle: 4.337 ± 0.05	3.365SerLys: 3.365 ± 0.041	6.241SerLeu: 6.241 ± 0.06	1.451SerMet: 1.451 ± 0.028	2.879SerAsn: 2.879 ± 0.046	2.49SerPro: 2.49 ± 0.039	1.91SerGln: 1.91 ± 0.032	2.731SerArg: 2.731 ± 0.04	4.249SerSer: 4.249 ± 0.061	3.464SerThr: 3.464 ± 0.045	4.579SerVal: 4.579 ± 0.058	0.867SerTrp: 0.867 ± 0.023	3.012SerTyr: 3.012 ± 0.045	0.0SerXaa: 0.0 ± 0.0
Thr	4.347ThrAla: 4.347 ± 0.053	0.559ThrCys: 0.559 ± 0.016	3.828ThrAsp: 3.828 ± 0.05	3.473ThrGlu: 3.473 ± 0.046	2.938ThrPhe: 2.938 ± 0.039	4.862ThrGly: 4.862 ± 0.059	0.951ThrHis: 0.951 ± 0.022	4.182ThrIle: 4.182 ± 0.052	2.954ThrLys: 2.954 ± 0.036	5.597ThrLeu: 5.597 ± 0.06	1.141ThrMet: 1.141 ± 0.023	2.831ThrAsn: 2.831 ± 0.04	2.981ThrPro: 2.981 ± 0.042	1.815ThrGln: 1.815 ± 0.025	2.193ThrArg: 2.193 ± 0.032	3.51ThrSer: 3.51 ± 0.049	3.606ThrThr: 3.606 ± 0.058	4.425ThrVal: 4.425 ± 0.064	0.723ThrTrp: 0.723 ± 0.022	2.57ThrTyr: 2.57 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	4.652ValAla: 4.652 ± 0.058	0.819ValCys: 0.819 ± 0.021	3.615ValAsp: 3.615 ± 0.05	3.929ValGlu: 3.929 ± 0.05	2.817ValPhe: 2.817 ± 0.043	3.931ValGly: 3.931 ± 0.051	0.971ValHis: 0.971 ± 0.026	4.339ValIle: 4.339 ± 0.045	4.43ValLys: 4.43 ± 0.059	5.763ValLeu: 5.763 ± 0.057	1.554ValMet: 1.554 ± 0.026	3.461ValAsn: 3.461 ± 0.052	2.582ValPro: 2.582 ± 0.032	1.915ValGln: 1.915 ± 0.031	2.838ValArg: 2.838 ± 0.046	4.811ValSer: 4.811 ± 0.053	4.181ValThr: 4.181 ± 0.066	4.341ValVal: 4.341 ± 0.055	0.786ValTrp: 0.786 ± 0.023	2.781ValTyr: 2.781 ± 0.034	0.0ValXaa: 0.0 ± 0.0
Trp	0.716TrpAla: 0.716 ± 0.02	0.165TrpCys: 0.165 ± 0.011	0.735TrpAsp: 0.735 ± 0.02	0.865TrpGlu: 0.865 ± 0.021	0.577TrpPhe: 0.577 ± 0.017	1.011TrpGly: 1.011 ± 0.027	0.275TrpHis: 0.275 ± 0.012	0.847TrpIle: 0.847 ± 0.024	0.942TrpLys: 0.942 ± 0.024	1.209TrpLeu: 1.209 ± 0.027	0.425TrpMet: 0.425 ± 0.016	0.784TrpAsn: 0.784 ± 0.022	0.315TrpPro: 0.315 ± 0.013	0.555TrpGln: 0.555 ± 0.017	0.586TrpArg: 0.586 ± 0.017	0.746TrpSer: 0.746 ± 0.022	0.711TrpThr: 0.711 ± 0.017	0.74TrpVal: 0.74 ± 0.022	0.213TrpTrp: 0.213 ± 0.01	0.548TrpTyr: 0.548 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.897TyrAla: 2.897 ± 0.044	0.516TyrCys: 0.516 ± 0.017	2.564TyrAsp: 2.564 ± 0.044	2.407TyrGlu: 2.407 ± 0.035	2.181TyrPhe: 2.181 ± 0.033	2.981TyrGly: 2.981 ± 0.045	0.83TyrHis: 0.83 ± 0.02	2.884TyrIle: 2.884 ± 0.04	2.811TyrLys: 2.811 ± 0.038	4.188TyrLeu: 4.188 ± 0.045	1.091TyrMet: 1.091 ± 0.026	2.701TyrAsn: 2.701 ± 0.042	2.033TyrPro: 2.033 ± 0.035	1.596TyrGln: 1.596 ± 0.03	2.233TyrArg: 2.233 ± 0.036	2.889TyrSer: 2.889 ± 0.039	2.946TyrThr: 2.946 ± 0.043	2.434TyrVal: 2.434 ± 0.036	0.594TyrTrp: 0.594 ± 0.018	2.252TyrTyr: 2.252 ± 0.039	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5316 proteins (2028514 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---