Vicugna pacos polyomavirus 1

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Sepolyvirales; Polyomaviridae; Betapolyomavirus

Average proteome isoelectric point is 6.19

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 5 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A1V0CLV5|A0A1V0CLV5_9POLY Small t antigen OS=Vicugna pacos polyomavirus 1 OX=2169757 PE=4 SV=1
MM1 pKa = 7.41GALLAIPEE9 pKa = 4.53IIAAFSIAGAEE20 pKa = 4.02ALEE23 pKa = 4.17ITGGSLAAIAAGEE36 pKa = 4.06GLAAAEE42 pKa = 4.51ALTEE46 pKa = 4.13SAALIGSEE54 pKa = 4.21ALTMSEE60 pKa = 4.75IGISDD65 pKa = 3.83AALTILSQTPQLVNEE80 pKa = 4.11AQAVGGLVNAAAGLAGGIAAFLEE103 pKa = 4.51PEE105 pKa = 4.11EE106 pKa = 4.74GNTGGVYY113 pKa = 10.3SQTSGSGWFGGFTWPPGAAAQPPLRR138 pKa = 11.84GPMDD142 pKa = 4.12AAVVPYY148 pKa = 10.82NEE150 pKa = 4.89LEE152 pKa = 4.04VGIPGIPDD160 pKa = 3.05WVLNMLPEE168 pKa = 4.7LPSLSDD174 pKa = 2.81IFSRR178 pKa = 11.84IAHH181 pKa = 6.85GIWTSYY187 pKa = 9.95YY188 pKa = 7.83NAGRR192 pKa = 11.84IVVQRR197 pKa = 11.84ALSSEE202 pKa = 4.11MQQLLRR208 pKa = 11.84DD209 pKa = 3.79LRR211 pKa = 11.84NGFSSTLQGIEE222 pKa = 4.1FSDD225 pKa = 4.01PVQAIANQIEE235 pKa = 4.62RR236 pKa = 11.84IQAQRR241 pKa = 11.84RR242 pKa = 11.84IDD244 pKa = 3.58NARR247 pKa = 11.84LLSYY251 pKa = 11.07AEE253 pKa = 4.21RR254 pKa = 11.84NQIDD258 pKa = 3.52VSNIVTALQEE268 pKa = 4.46GAQTAAGALRR278 pKa = 11.84DD279 pKa = 3.59AGGAVVGQVGNLAMDD294 pKa = 4.37IANLPIDD301 pKa = 4.94GYY303 pKa = 11.23NALSDD308 pKa = 3.69GVHH311 pKa = 7.05RR312 pKa = 11.84FGQWISISGPTGGTEE327 pKa = 4.16HH328 pKa = 6.99YY329 pKa = 10.86SFPDD333 pKa = 2.71WMLYY337 pKa = 10.43LLEE340 pKa = 4.3EE341 pKa = 4.55VEE343 pKa = 4.27TDD345 pKa = 3.93FTPRR349 pKa = 11.84VPLKK353 pKa = 10.77RR354 pKa = 11.84KK355 pKa = 10.12LEE357 pKa = 4.19EE358 pKa = 3.96NNGNQRR364 pKa = 11.84KK365 pKa = 9.15KK366 pKa = 10.5RR367 pKa = 11.84STGAKK372 pKa = 8.77TSSKK376 pKa = 9.46TSKK379 pKa = 8.86TSKK382 pKa = 9.94KK383 pKa = 9.83RR384 pKa = 11.84RR385 pKa = 11.84SS386 pKa = 3.28

Molecular weight: 40.6 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A1V0CLV8|A0A1V0CLV8_9POLY Major capsid protein VP1 OS=Vicugna pacos polyomavirus 1 OX=2169757 GN=VP1 PE=3 SV=1
MM1 pKa = 7.95DD2 pKa = 3.65RR3 pKa = 11.84TLDD6 pKa = 3.6RR7 pKa = 11.84EE8 pKa = 4.11EE9 pKa = 4.61SKK11 pKa = 11.33EE12 pKa = 3.91LMALLGLSMSCWGNIPMMRR31 pKa = 11.84RR32 pKa = 11.84AYY34 pKa = 9.44KK35 pKa = 8.07VQCRR39 pKa = 11.84NLHH42 pKa = 6.06PDD44 pKa = 2.89KK45 pKa = 11.51GGDD48 pKa = 3.52EE49 pKa = 4.33EE50 pKa = 4.56KK51 pKa = 10.29MKK53 pKa = 10.78RR54 pKa = 11.84LTEE57 pKa = 4.23LYY59 pKa = 10.15KK60 pKa = 10.81KK61 pKa = 10.77LEE63 pKa = 3.99EE64 pKa = 4.16TLGVIHH70 pKa = 6.28SQNEE74 pKa = 4.23SEE76 pKa = 4.14EE77 pKa = 4.55GSWNASEE84 pKa = 5.44VVLSDD89 pKa = 4.37PNCPCCQNLAGLNIGDD105 pKa = 3.67IYY107 pKa = 11.4GDD109 pKa = 3.39IFSEE113 pKa = 5.26LIVKK117 pKa = 9.99DD118 pKa = 3.46WLSCKK123 pKa = 10.43LGWNTKK129 pKa = 7.4CTCFMCKK136 pKa = 9.16LRR138 pKa = 11.84RR139 pKa = 11.84RR140 pKa = 11.84HH141 pKa = 5.53RR142 pKa = 11.84LRR144 pKa = 11.84VKK146 pKa = 10.13AYY148 pKa = 9.12KK149 pKa = 10.28RR150 pKa = 11.84PLKK153 pKa = 9.94WVEE156 pKa = 4.4CYY158 pKa = 10.62CFEE161 pKa = 5.83CYY163 pKa = 10.55VEE165 pKa = 4.11WFGFCRR171 pKa = 11.84TFEE174 pKa = 4.84ANFWWQKK181 pKa = 10.77IIFFTPFLEE190 pKa = 4.68IKK192 pKa = 10.39LL193 pKa = 3.95

Molecular weight: 22.9 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

5

0

5

1850

193

657

370.0

41.47

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.432 ± 1.768

1.838 ± 0.828

4.649 ± 0.624

7.081 ± 0.592

3.73 ± 0.393

7.838 ± 1.26

1.459 ± 0.217

5.459 ± 0.586

5.946 ± 1.271

9.297 ± 0.399

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.757 ± 0.437

5.892 ± 0.506

4.973 ± 0.723

4.649 ± 0.491

4.919 ± 0.601

5.892 ± 0.782

5.514 ± 0.85

6.541 ± 1.045

1.784 ± 0.37

3.351 ± 0.408
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski