Toxocara canis (Canine roundworm)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara

Average proteome isoelectric point is 6.98

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 18499 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A0B2UV47|A0A0B2UV47_TOXCA UPF0046 protein C25E10.12 OS=Toxocara canis OX=6265 GN=C25E10.12 PE=4 SV=1
MM1 pKa = 7.16CTDD4 pKa = 2.86VDD6 pKa = 4.41MSLEE10 pKa = 4.11MCTDD14 pKa = 2.63VHH16 pKa = 6.43MSLEE20 pKa = 4.51TYY22 pKa = 10.33TDD24 pKa = 2.98VDD26 pKa = 3.64VSLEE30 pKa = 4.03VCTDD34 pKa = 2.77VDD36 pKa = 3.89MSLAMCTDD44 pKa = 3.04VDD46 pKa = 4.6VSLEE50 pKa = 4.07TCTDD54 pKa = 3.53VVVSLDD60 pKa = 3.17MCTDD64 pKa = 3.18VDD66 pKa = 4.7VSPDD70 pKa = 2.99MCTDD74 pKa = 2.88VDD76 pKa = 4.58VSLKK80 pKa = 9.75MCTDD84 pKa = 3.23VDD86 pKa = 4.26VSPDD90 pKa = 2.99MCTDD94 pKa = 2.88VDD96 pKa = 4.58VSLKK100 pKa = 9.75MCTDD104 pKa = 3.23VDD106 pKa = 4.26VSPDD110 pKa = 2.99MCTDD114 pKa = 2.88VDD116 pKa = 4.58VSLKK120 pKa = 9.75MCTDD124 pKa = 3.23VDD126 pKa = 4.26VSPDD130 pKa = 2.99MCTDD134 pKa = 2.88VDD136 pKa = 4.58VSLKK140 pKa = 9.75MCTDD144 pKa = 3.23VDD146 pKa = 4.26VSPDD150 pKa = 2.99MCTDD154 pKa = 2.88VDD156 pKa = 4.58VSLKK160 pKa = 9.75MCTDD164 pKa = 2.97VDD166 pKa = 4.19VSLKK170 pKa = 9.77MCTDD174 pKa = 2.8MDD176 pKa = 3.48VRR178 pKa = 11.84RR179 pKa = 11.84IQFSCDD185 pKa = 2.65VFLANDD191 pKa = 4.5FSNKK195 pKa = 6.85TLKK198 pKa = 10.69DD199 pKa = 3.58SLLMIVRR206 pKa = 11.84QRR208 pKa = 11.84INVEE212 pKa = 4.14FYY214 pKa = 11.04DD215 pKa = 3.98PFLLRR220 pKa = 11.84ILAEE224 pKa = 3.98NSLKK228 pKa = 10.79KK229 pKa = 10.55FF230 pKa = 3.55

Molecular weight: 25.59 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A0B2W3E4|A0A0B2W3E4_TOXCA Uncharacterized protein OS=Toxocara canis OX=6265 GN=Tcan_12348 PE=4 SV=1
MM1 pKa = 7.3TGQRR5 pKa = 11.84SMTGQRR11 pKa = 11.84SMTGQRR17 pKa = 11.84SMTGQRR23 pKa = 11.84SMTGQRR29 pKa = 11.84SMTGQRR35 pKa = 11.84SMTGQRR41 pKa = 11.84SMTGQRR47 pKa = 11.84SMTGQRR53 pKa = 11.84SMTGQRR59 pKa = 11.84SMTGQRR65 pKa = 11.84SMTGQRR71 pKa = 11.84SMTGQRR77 pKa = 11.84SMTGQRR83 pKa = 11.84SMTGQRR89 pKa = 11.84SMTGQRR95 pKa = 11.84SMTGQRR101 pKa = 11.84SMTGQRR107 pKa = 11.84SMTGQRR113 pKa = 11.84SMTGQRR119 pKa = 11.84SMTGQRR125 pKa = 11.84SMTGQRR131 pKa = 11.84SMTGQRR137 pKa = 11.84SMTGQRR143 pKa = 11.84SMTGQRR149 pKa = 11.84SMTGQRR155 pKa = 11.84SMTGQRR161 pKa = 11.84SMTGQRR167 pKa = 11.84SMTGQRR173 pKa = 11.84SMTGQRR179 pKa = 11.84SMTGQRR185 pKa = 11.84SMTGQRR191 pKa = 11.84SMTGQRR197 pKa = 11.84SILLVIEE204 pKa = 4.49PSFF207 pKa = 3.69

Molecular weight: 22.83 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

18499

0

18499

7137888

24

11591

385.9

43.25

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.537 ± 0.019

2.283 ± 0.018

5.221 ± 0.015

6.599 ± 0.027

4.056 ± 0.016

5.661 ± 0.028

2.413 ± 0.01

5.382 ± 0.016

5.361 ± 0.019

8.932 ± 0.027

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.532 ± 0.01

4.194 ± 0.014

4.854 ± 0.026

3.963 ± 0.016

6.435 ± 0.019

8.368 ± 0.026

5.583 ± 0.021

6.57 ± 0.024

1.14 ± 0.009

2.882 ± 0.012
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski