Mount Mabu Lophuromys virus 2

Taxonomy: Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina; Monjiviricetes; Mononegavirales; Paramyxoviridae; Orthoparamyxovirinae; Jeilongvirus; Lophuromys jeilongvirus 2

Average proteome isoelectric point is 6.89

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 8 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|A0A2P1GJB4|A0A2P1GJB4_9MONO Putative TM protein OS=Mount Mabu Lophuromys virus 2 OX=2116560 GN=TM PE=4 SV=1
MM1 pKa = 7.42SRR3 pKa = 11.84LNSVLEE9 pKa = 3.93EE10 pKa = 3.68FRR12 pKa = 11.84EE13 pKa = 4.56FKK15 pKa = 10.95NNPPKK20 pKa = 10.51RR21 pKa = 11.84GLISSALHH29 pKa = 5.62GLKK32 pKa = 10.19KK33 pKa = 10.57SVIIPVPTFVDD44 pKa = 5.5PIQRR48 pKa = 11.84WYY50 pKa = 11.26FMVFMLEE57 pKa = 4.23LAWSNVASGSIMTGALLSLLSLFAEE82 pKa = 4.63NPGAMVRR89 pKa = 11.84SLLNDD94 pKa = 3.86PDD96 pKa = 5.16LDD98 pKa = 3.89VQIAEE103 pKa = 4.23VSRR106 pKa = 11.84ASKK109 pKa = 11.13DD110 pKa = 3.6EE111 pKa = 3.99IKK113 pKa = 10.8LATRR117 pKa = 11.84GKK119 pKa = 10.53NMEE122 pKa = 4.66DD123 pKa = 3.63YY124 pKa = 10.12EE125 pKa = 5.01KK126 pKa = 10.99EE127 pKa = 4.13LIRR130 pKa = 11.84IAGYY134 pKa = 10.52GPYY137 pKa = 9.71QGTKK141 pKa = 8.49TDD143 pKa = 3.89PFPFVKK149 pKa = 10.01KK150 pKa = 10.42DD151 pKa = 3.31QDD153 pKa = 3.34KK154 pKa = 10.56MITKK158 pKa = 7.73TTEE161 pKa = 3.77DD162 pKa = 3.41LQLAVQTVTIQIWILLTKK180 pKa = 10.49AVTATDD186 pKa = 3.53TAKK189 pKa = 10.56EE190 pKa = 4.22SEE192 pKa = 3.71NRR194 pKa = 11.84RR195 pKa = 11.84WVKK198 pKa = 10.28YY199 pKa = 8.73LQQRR203 pKa = 11.84RR204 pKa = 11.84ADD206 pKa = 3.9RR207 pKa = 11.84DD208 pKa = 3.7YY209 pKa = 11.53KK210 pKa = 11.38LEE212 pKa = 4.21DD213 pKa = 2.83TWLNLARR220 pKa = 11.84ARR222 pKa = 11.84IAEE225 pKa = 4.77DD226 pKa = 2.91ISVRR230 pKa = 11.84RR231 pKa = 11.84YY232 pKa = 7.94MVEE235 pKa = 4.0ILIEE239 pKa = 4.23TNKK242 pKa = 9.28MAGVKK247 pKa = 8.91TRR249 pKa = 11.84IVEE252 pKa = 4.32MISDD256 pKa = 3.73IGNYY260 pKa = 9.35ISEE263 pKa = 4.29AGMAGFFLTIKK274 pKa = 10.67YY275 pKa = 10.24GIEE278 pKa = 3.86TKK280 pKa = 10.96YY281 pKa = 10.24PALALNEE288 pKa = 4.12LQADD292 pKa = 4.15LSIILSLMKK301 pKa = 10.07TYY303 pKa = 10.66TSLGEE308 pKa = 3.87KK309 pKa = 9.73APYY312 pKa = 9.25MVILEE317 pKa = 4.66DD318 pKa = 5.19AIQTKK323 pKa = 9.64FSPGNYY329 pKa = 8.42PLLWSYY335 pKa = 12.02AMGVGSVLDD344 pKa = 3.37RR345 pKa = 11.84AVNNLNYY352 pKa = 8.54TRR354 pKa = 11.84PYY356 pKa = 10.0LEE358 pKa = 4.81HH359 pKa = 7.66SFFQLGEE366 pKa = 4.21TMVEE370 pKa = 4.02KK371 pKa = 10.78MEE373 pKa = 4.12GTVNNRR379 pKa = 11.84IAAEE383 pKa = 4.19LDD385 pKa = 3.43LSPEE389 pKa = 4.09QVQSIRR395 pKa = 11.84SIVKK399 pKa = 10.0LDD401 pKa = 3.47QATSGPRR408 pKa = 11.84VSGPQQKK415 pKa = 8.89TSGPRR420 pKa = 11.84PFEE423 pKa = 4.37LYY425 pKa = 10.27NAGDD429 pKa = 4.58IIPEE433 pKa = 3.98IEE435 pKa = 4.37EE436 pKa = 4.15EE437 pKa = 4.93VSDD440 pKa = 4.03EE441 pKa = 4.37DD442 pKa = 5.32KK443 pKa = 11.28KK444 pKa = 10.97DD445 pKa = 3.36TYY447 pKa = 11.16DD448 pKa = 3.18VSKK451 pKa = 10.96VVPVPNANSIFYY463 pKa = 10.93DD464 pKa = 4.06KK465 pKa = 11.22DD466 pKa = 3.4NQKK469 pKa = 11.06DD470 pKa = 3.62KK471 pKa = 11.47RR472 pKa = 11.84NLPKK476 pKa = 10.02PPKK479 pKa = 9.28PSRR482 pKa = 11.84SGKK485 pKa = 9.64KK486 pKa = 9.6VNNLKK491 pKa = 10.64EE492 pKa = 4.29SLNDD496 pKa = 3.6ALEE499 pKa = 4.37DD500 pKa = 4.0FVRR503 pKa = 11.84DD504 pKa = 3.16EE505 pKa = 6.06SMTQKK510 pKa = 10.62LNKK513 pKa = 9.57YY514 pKa = 10.38DD515 pKa = 4.2EE516 pKa = 5.63DD517 pKa = 4.08DD518 pKa = 3.46VSYY521 pKa = 10.04STDD524 pKa = 3.21QSPATMSDD532 pKa = 3.09LDD534 pKa = 3.81ALRR537 pKa = 11.84SS538 pKa = 3.64

Molecular weight:
60.8 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|A0A2P1GJ92|A0A2P1GJ92_9MONO RNA-directed RNA polymerase L OS=Mount Mabu Lophuromys virus 2 OX=2116560 GN=L PE=3 SV=1
MM1 pKa = 7.51EE2 pKa = 5.31SALSTLSSRR11 pKa = 11.84IRR13 pKa = 11.84RR14 pKa = 11.84TFRR17 pKa = 11.84RR18 pKa = 11.84HH19 pKa = 4.34TGEE22 pKa = 3.99VQSINHH28 pKa = 5.52QPRR31 pKa = 11.84IEE33 pKa = 3.99QRR35 pKa = 11.84RR36 pKa = 11.84GRR38 pKa = 11.84PSQRR42 pKa = 11.84VRR44 pKa = 11.84VEE46 pKa = 4.02DD47 pKa = 3.88LSVNPGEE54 pKa = 4.01WEE56 pKa = 3.79AAKK59 pKa = 8.75EE60 pKa = 4.31TRR62 pKa = 11.84KK63 pKa = 8.67RR64 pKa = 11.84TAAEE68 pKa = 3.72VLEE71 pKa = 5.52LIDD74 pKa = 4.0HH75 pKa = 6.76LEE77 pKa = 4.25SKK79 pKa = 9.15GTEE82 pKa = 3.79VTAPRR87 pKa = 11.84TPRR90 pKa = 11.84EE91 pKa = 3.67QEE93 pKa = 4.08MITKK97 pKa = 10.49LGMLKK102 pKa = 9.94ILLNLVKK109 pKa = 9.34EE110 pKa = 4.5TGVIPDD116 pKa = 4.38PNKK119 pKa = 10.42QSIQQSGLLTRR130 pKa = 11.84VEE132 pKa = 4.14MEE134 pKa = 4.47NLGEE138 pKa = 4.41MIPALKK144 pKa = 10.5SILKK148 pKa = 9.84NN149 pKa = 3.45

Molecular weight:
16.96 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

8

0

8

5346

149

2188

668.3

75.43

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

4.863 ± 0.361

1.553 ± 0.373

5.724 ± 0.414

5.556 ± 0.499

3.236 ± 0.351

5.743 ± 0.709

2.132 ± 0.411

7.838 ± 0.535

6.023 ± 0.675

9.39 ± 0.814

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.768 ± 0.186

6.192 ± 0.389

3.984 ± 0.297

3.498 ± 0.287

5.051 ± 0.336

8.474 ± 0.395

6.921 ± 1.003

5.855 ± 0.529

1.066 ± 0.141

4.134 ± 0.56

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski