Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Fungi; Dikarya; Ascomycota; saccharomyceta; Saccharomycotina; Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida; Candida tropicalis

Average proteome isoelectric point is 6.28

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 6226 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|C5M4U6|C5M4U6_CANTT Hyphal_reg_CWP domain-containing protein (Fragment) OS=Candida tropicalis (strain ATCC MYA-3404 / T1) OX=294747 GN=CTRG_01924 PE=4 SV=1
MM1 pKa = 7.57LLLRR5 pKa = 11.84PISLTLVFLFNYY17 pKa = 9.96ALSKK21 pKa = 10.77DD22 pKa = 3.59ITVDD26 pKa = 3.19TVDD29 pKa = 3.92RR30 pKa = 11.84GSISLSVGDD39 pKa = 4.27INIHH43 pKa = 6.13TGASWSIINNAVSALAGSLNVEE65 pKa = 4.21SDD67 pKa = 2.96AGFYY71 pKa = 8.7ITSTSPLIGLDD82 pKa = 3.34VTLLSTLGSIVNDD95 pKa = 4.98GIIAFNSVKK104 pKa = 10.6SLTSSTYY111 pKa = 10.11NLVGAKK117 pKa = 9.94FEE119 pKa = 5.2NNGEE123 pKa = 4.21MYY125 pKa = 10.64LGASGVLSGTMSITSLSWKK144 pKa = 10.43NSGLLVFYY152 pKa = 10.52QNQRR156 pKa = 11.84NSGDD160 pKa = 3.47VRR162 pKa = 11.84LGTPLGSITNDD173 pKa = 3.28GQICLINQVYY183 pKa = 9.59RR184 pKa = 11.84QTNDD188 pKa = 2.54IKK190 pKa = 11.25GSGCITAQKK199 pKa = 10.64NSTIYY204 pKa = 10.21IPSAIQSFDD213 pKa = 3.57TQQSIYY219 pKa = 10.62LKK221 pKa = 10.24DD222 pKa = 3.72SEE224 pKa = 4.82SSIIVQALSTAQTFNVYY241 pKa = 10.52GFGNGNKK248 pKa = 9.48IGLTVPLVGNLIPSYY263 pKa = 9.93PAYY266 pKa = 9.78KK267 pKa = 9.83YY268 pKa = 10.72DD269 pKa = 3.69EE270 pKa = 4.38STGILTLRR278 pKa = 11.84NLLLKK283 pKa = 10.77QNFNIGLGYY292 pKa = 10.22SSSLFQIVTDD302 pKa = 4.06SGIGLPSTLLGSVQYY317 pKa = 10.41NGPVPEE323 pKa = 4.33RR324 pKa = 11.84SISATCQIEE333 pKa = 4.71CKK335 pKa = 9.53EE336 pKa = 4.1LPEE339 pKa = 4.95APGVEE344 pKa = 3.97PTEE347 pKa = 4.07YY348 pKa = 10.1LTTLTSTLSDD358 pKa = 3.25GSVTTEE364 pKa = 3.68SGIVDD369 pKa = 3.75VTTDD373 pKa = 4.2SSGSWYY379 pKa = 6.9TTTSLFPPLSSSSSEE394 pKa = 4.17VVSSSSEE401 pKa = 3.75IVSSTEE407 pKa = 3.98RR408 pKa = 11.84EE409 pKa = 3.87SSLQSFSEE417 pKa = 4.35YY418 pKa = 10.48FNSSSSYY425 pKa = 10.51AFEE428 pKa = 4.2STSSILEE435 pKa = 4.29SSSHH439 pKa = 6.4PSSEE443 pKa = 4.2VSSTQDD449 pKa = 3.37DD450 pKa = 3.69ASEE453 pKa = 5.03SNFSTSSLISEE464 pKa = 4.55SNVLEE469 pKa = 4.39SSDD472 pKa = 3.94ASATSDD478 pKa = 3.3VSSASDD484 pKa = 2.95ISSASDD490 pKa = 3.39ASDD493 pKa = 3.58SDD495 pKa = 3.94PSSTSDD501 pKa = 3.12VSSASDD507 pKa = 2.98ISSASDD513 pKa = 2.88ISSTSEE519 pKa = 3.52IASSSNTSSASDD531 pKa = 2.96ISTSSDD537 pKa = 2.83ASEE540 pKa = 4.63SNASATSGASSASDD554 pKa = 2.94ARR556 pKa = 11.84EE557 pKa = 4.15SNASATSGASDD568 pKa = 3.69ASEE571 pKa = 4.21SDD573 pKa = 3.36ASATSGASDD582 pKa = 3.69ASEE585 pKa = 4.21SDD587 pKa = 3.36ASATSGASDD596 pKa = 3.23ASEE599 pKa = 4.44SNASATSGASDD610 pKa = 3.23ASEE613 pKa = 4.44SNASATSGASSASDD627 pKa = 3.09ASEE630 pKa = 4.01SDD632 pKa = 3.36ASATSGASEE641 pKa = 3.94ASEE644 pKa = 4.53SNASATSGASSASDD658 pKa = 3.04ASSASDD664 pKa = 3.44ANKK667 pKa = 10.61SNAPATSGASDD678 pKa = 3.52ASEE681 pKa = 4.24SDD683 pKa = 3.37ASSTSDD689 pKa = 3.13ASPSYY694 pKa = 10.98NHH696 pKa = 6.91IEE698 pKa = 4.1STEE701 pKa = 4.07SDD703 pKa = 3.58VQAEE707 pKa = 4.43FTTTWTTTNSDD718 pKa = 3.13GSVEE722 pKa = 4.21TEE724 pKa = 3.89SGIVSQSGSSFTTLTTFPPEE744 pKa = 3.78YY745 pKa = 10.12DD746 pKa = 3.59VPSS749 pKa = 3.61

Molecular weight:
76.05 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|C5M514|C5M514_CANTT Zn(2)-C6 fungal-type domain-containing protein OS=Candida tropicalis (strain ATCC MYA-3404 / T1) OX=294747 GN=CTRG_01992 PE=4 SV=1
MM1 pKa = 7.35IVEE4 pKa = 5.08RR5 pKa = 11.84IKK7 pKa = 10.43MAIQFQVIVLSALIIIISQNWINVVLMIRR36 pKa = 11.84IRR38 pKa = 11.84LSHH41 pKa = 5.57VVIGHH46 pKa = 5.13GTEE49 pKa = 3.78SQYY52 pKa = 11.42LVPHH56 pKa = 5.89QLLPVKK62 pKa = 10.32FHH64 pKa = 5.91HH65 pKa = 6.31HH66 pKa = 4.18QVKK69 pKa = 9.97KK70 pKa = 9.85FHH72 pKa = 6.12HH73 pKa = 6.38HH74 pKa = 4.83PVKK77 pKa = 10.38RR78 pKa = 11.84FHH80 pKa = 6.09LHH82 pKa = 3.58QVKK85 pKa = 9.94RR86 pKa = 11.84FHH88 pKa = 6.64LHH90 pKa = 4.78HH91 pKa = 6.11QRR93 pKa = 11.84KK94 pKa = 7.87FHH96 pKa = 5.28QAPVKK101 pKa = 10.12RR102 pKa = 11.84SHH104 pKa = 5.4QAPVKK109 pKa = 10.07RR110 pKa = 11.84SHH112 pKa = 5.34QVPVKK117 pKa = 10.16RR118 pKa = 11.84FHH120 pKa = 6.01LHH122 pKa = 3.96QVKK125 pKa = 9.94KK126 pKa = 9.51FHH128 pKa = 5.9QAPVKK133 pKa = 10.18KK134 pKa = 10.11FHH136 pKa = 6.22LHH138 pKa = 4.7PVKK141 pKa = 10.39RR142 pKa = 11.84FHH144 pKa = 6.82LHH146 pKa = 4.81HH147 pKa = 6.11QRR149 pKa = 11.84KK150 pKa = 7.87FHH152 pKa = 5.28QAPVKK157 pKa = 10.2RR158 pKa = 11.84SHH160 pKa = 5.34QVPVKK165 pKa = 10.0RR166 pKa = 11.84FHH168 pKa = 5.98HH169 pKa = 6.16HH170 pKa = 4.8PVKK173 pKa = 10.44RR174 pKa = 11.84FHH176 pKa = 6.67LHH178 pKa = 4.81HH179 pKa = 6.11QRR181 pKa = 11.84KK182 pKa = 7.87FHH184 pKa = 5.28QAPVKK189 pKa = 10.2RR190 pKa = 11.84SHH192 pKa = 5.47QVPVKK197 pKa = 10.13KK198 pKa = 10.23FHH200 pKa = 6.04LRR202 pKa = 11.84QVKK205 pKa = 9.87RR206 pKa = 11.84SHH208 pKa = 5.15QAPVKK213 pKa = 10.07RR214 pKa = 11.84SHH216 pKa = 5.34QVPVKK221 pKa = 10.16RR222 pKa = 11.84FHH224 pKa = 5.92LHH226 pKa = 3.58QVKK229 pKa = 10.08RR230 pKa = 11.84SHH232 pKa = 5.39QAPVKK237 pKa = 10.07RR238 pKa = 11.84SHH240 pKa = 5.34QVPVKK245 pKa = 10.16RR246 pKa = 11.84FHH248 pKa = 6.01LHH250 pKa = 3.96QVKK253 pKa = 9.94KK254 pKa = 9.51FHH256 pKa = 5.9QAPVKK261 pKa = 10.18KK262 pKa = 10.11FHH264 pKa = 6.22LHH266 pKa = 4.7PVKK269 pKa = 10.32RR270 pKa = 11.84FHH272 pKa = 6.16LHH274 pKa = 3.58QVKK277 pKa = 9.88RR278 pKa = 11.84FHH280 pKa = 6.04LHH282 pKa = 3.58QVKK285 pKa = 10.05RR286 pKa = 11.84SHH288 pKa = 5.84LHH290 pKa = 3.74QVKK293 pKa = 9.99RR294 pKa = 11.84SHH296 pKa = 5.84LHH298 pKa = 3.71QVKK301 pKa = 9.97RR302 pKa = 11.84SHH304 pKa = 5.39QAPVKK309 pKa = 10.07RR310 pKa = 11.84SHH312 pKa = 5.38QVPVKK317 pKa = 10.26KK318 pKa = 10.84VPTKK322 pKa = 10.44FQQ324 pKa = 3.37

Molecular weight:
39.39 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

6226

0

6226

3018650

50

3808

484.8

54.78

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.05 ± 0.037

1.101 ± 0.009

5.983 ± 0.026

6.759 ± 0.033

4.491 ± 0.021

5.091 ± 0.033

2.072 ± 0.013

7.064 ± 0.026

7.222 ± 0.038

9.14 ± 0.037

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.882 ± 0.011

6.269 ± 0.027

4.553 ± 0.03

4.272 ± 0.025

3.821 ± 0.018

9.06 ± 0.045

5.992 ± 0.039

5.623 ± 0.024

0.984 ± 0.01

3.571 ± 0.017

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski