Cimex lectularius (Bed bug) (Acanthia lectularia)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Ecdysozoa; Panarthropoda; Arthropoda; Mandibulata; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota; Neoptera; Paraneoptera; Hemiptera; Prosorrhyncha; Heteroptera; Euheteroptera; Neoheteroptera; Panheteroptera;

Average proteome isoelectric point is 7.03

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 14152 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A7E4RCQ5|A0A7E4RCQ5_CIMLE Uncharacterized protein OS=Cimex lectularius OX=79782 PE=4 SV=1
MM1 pKa = 8.43AMIFLFGLVLTSGSSRR17 pKa = 11.84SQDD20 pKa = 3.46LTSDD24 pKa = 3.6DD25 pKa = 3.68YY26 pKa = 11.86DD27 pKa = 3.82YY28 pKa = 12.18ANITSNDD35 pKa = 3.36TSQGAGQIMFWNEE48 pKa = 3.08TSFNDD53 pKa = 4.17TALLDD58 pKa = 3.63IPLQSEE64 pKa = 4.67SPGFWEE70 pKa = 5.66AYY72 pKa = 8.29EE73 pKa = 4.3SQNGTVLEE81 pKa = 4.8SISFHH86 pKa = 6.71PNPVTYY92 pKa = 10.69GLLDD96 pKa = 3.78GEE98 pKa = 4.86TAVTPYY104 pKa = 9.75MGEE107 pKa = 3.69EE108 pKa = 4.12DD109 pKa = 4.5AVSKK113 pKa = 10.56PVGDD117 pKa = 4.22LWPVKK122 pKa = 10.02LAAEE126 pKa = 4.38VPGDD130 pKa = 4.49LILGGLMMVHH140 pKa = 5.93EE141 pKa = 5.23RR142 pKa = 11.84EE143 pKa = 4.2DD144 pKa = 4.07TITCGPVMPQGGIQAVEE161 pKa = 3.77IMLYY165 pKa = 9.21TLDD168 pKa = 4.91IINEE172 pKa = 4.15RR173 pKa = 11.84LGHH176 pKa = 4.98YY177 pKa = 8.83TLGAHH182 pKa = 7.29ILDD185 pKa = 4.86DD186 pKa = 4.5CDD188 pKa = 4.21KK189 pKa = 10.3DD190 pKa = 3.98TYY192 pKa = 9.98GLEE195 pKa = 4.02MAVDD199 pKa = 4.68FIKK202 pKa = 11.0GKK204 pKa = 10.43LNFYY208 pKa = 9.6FVKK211 pKa = 9.99TT212 pKa = 3.8

Molecular weight: 23.28 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A7E4S0M5|A0A7E4S0M5_CIMLE L-lactate dehydrogenase OS=Cimex lectularius OX=79782 PE=3 SV=1
MM1 pKa = 7.41SAHH4 pKa = 6.35KK5 pKa = 9.26TFKK8 pKa = 10.71VKK10 pKa = 10.47QKK12 pKa = 10.09LAKK15 pKa = 9.8KK16 pKa = 9.96LKK18 pKa = 8.58QNRR21 pKa = 11.84PIPQWIRR28 pKa = 11.84MRR30 pKa = 11.84TGNTIRR36 pKa = 11.84YY37 pKa = 5.79NAKK40 pKa = 8.47RR41 pKa = 11.84RR42 pKa = 11.84HH43 pKa = 4.1WRR45 pKa = 11.84RR46 pKa = 11.84TKK48 pKa = 10.89LKK50 pKa = 10.55LL51 pKa = 3.39

Molecular weight: 6.34 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

14051

101

14152

5704716

14

13863

403.1

45.5

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.758 ± 0.021

1.996 ± 0.029

5.234 ± 0.017

6.732 ± 0.032

4.187 ± 0.02

5.818 ± 0.034

2.467 ± 0.012

5.96 ± 0.024

7.042 ± 0.029

9.361 ± 0.035

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.401 ± 0.01

4.913 ± 0.017

4.976 ± 0.033

3.917 ± 0.02

5.042 ± 0.019

7.704 ± 0.027

5.61 ± 0.017

6.44 ± 0.017

1.124 ± 0.009

3.31 ± 0.014
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski