Amino acid dipepetide frequency for Aliifodinibius roseus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.003AlaAla: 6.003 ± 0.076	0.559AlaCys: 0.559 ± 0.021	4.339AlaAsp: 4.339 ± 0.064	5.364AlaGlu: 5.364 ± 0.078	3.15AlaPhe: 3.15 ± 0.047	6.167AlaGly: 6.167 ± 0.073	1.315AlaHis: 1.315 ± 0.03	4.486AlaIle: 4.486 ± 0.07	2.905AlaLys: 2.905 ± 0.053	6.842AlaLeu: 6.842 ± 0.079	1.701AlaMet: 1.701 ± 0.04	2.634AlaAsn: 2.634 ± 0.04	2.478AlaPro: 2.478 ± 0.045	2.581AlaGln: 2.581 ± 0.051	3.982AlaArg: 3.982 ± 0.059	4.545AlaSer: 4.545 ± 0.063	3.608AlaThr: 3.608 ± 0.051	5.074AlaVal: 5.074 ± 0.071	0.874AlaTrp: 0.874 ± 0.024	2.469AlaTyr: 2.469 ± 0.042	0.0AlaXaa: 0.0 ± 0.0
Cys	0.428CysAla: 0.428 ± 0.017	0.118CysCys: 0.118 ± 0.01	0.372CysAsp: 0.372 ± 0.016	0.412CysGlu: 0.412 ± 0.021	0.327CysPhe: 0.327 ± 0.015	0.586CysGly: 0.586 ± 0.021	0.219CysHis: 0.219 ± 0.015	0.431CysIle: 0.431 ± 0.017	0.279CysLys: 0.279 ± 0.014	0.591CysLeu: 0.591 ± 0.021	0.158CysMet: 0.158 ± 0.01	0.262CysAsn: 0.262 ± 0.015	0.299CysPro: 0.299 ± 0.017	0.195CysGln: 0.195 ± 0.012	0.416CysArg: 0.416 ± 0.019	0.52CysSer: 0.52 ± 0.018	0.379CysThr: 0.379 ± 0.018	0.395CysVal: 0.395 ± 0.017	0.084CysTrp: 0.084 ± 0.008	0.249CysTyr: 0.249 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	3.73AspAla: 3.73 ± 0.052	0.311AspCys: 0.311 ± 0.017	3.274AspAsp: 3.274 ± 0.051	4.572AspGlu: 4.572 ± 0.057	2.959AspPhe: 2.959 ± 0.051	4.306AspGly: 4.306 ± 0.08	1.522AspHis: 1.522 ± 0.034	4.538AspIle: 4.538 ± 0.061	2.866AspLys: 2.866 ± 0.051	5.709AspLeu: 5.709 ± 0.075	1.409AspMet: 1.409 ± 0.035	2.55AspAsn: 2.55 ± 0.044	3.107AspPro: 3.107 ± 0.056	2.408AspGln: 2.408 ± 0.045	3.741AspArg: 3.741 ± 0.058	3.469AspSer: 3.469 ± 0.057	3.139AspThr: 3.139 ± 0.047	3.496AspVal: 3.496 ± 0.051	0.961AspTrp: 0.961 ± 0.027	2.508AspTyr: 2.508 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	5.838GluAla: 5.838 ± 0.071	0.332GluCys: 0.332 ± 0.017	4.39GluAsp: 4.39 ± 0.066	7.309GluGlu: 7.309 ± 0.094	2.515GluPhe: 2.515 ± 0.039	5.473GluGly: 5.473 ± 0.066	1.681GluHis: 1.681 ± 0.039	4.878GluIle: 4.878 ± 0.07	4.545GluLys: 4.545 ± 0.069	6.964GluLeu: 6.964 ± 0.076	1.972GluMet: 1.972 ± 0.04	3.409GluAsn: 3.409 ± 0.057	2.549GluPro: 2.549 ± 0.044	3.748GluGln: 3.748 ± 0.05	3.911GluArg: 3.911 ± 0.052	3.88GluSer: 3.88 ± 0.057	3.841GluThr: 3.841 ± 0.053	5.163GluVal: 5.163 ± 0.065	1.015GluTrp: 1.015 ± 0.029	2.588GluTyr: 2.588 ± 0.04	0.0GluXaa: 0.0 ± 0.0
Phe	2.867PheAla: 2.867 ± 0.048	0.346PheCys: 0.346 ± 0.018	2.917PheAsp: 2.917 ± 0.05	3.092PheGlu: 3.092 ± 0.047	2.153PhePhe: 2.153 ± 0.046	3.287PheGly: 3.287 ± 0.046	0.817PheHis: 0.817 ± 0.023	2.728PheIle: 2.728 ± 0.046	1.876PheLys: 1.876 ± 0.035	4.09PheLeu: 4.09 ± 0.067	1.023PheMet: 1.023 ± 0.026	2.106PheAsn: 2.106 ± 0.043	1.709PhePro: 1.709 ± 0.034	1.409PheGln: 1.409 ± 0.034	2.324PheArg: 2.324 ± 0.047	3.269PheSer: 3.269 ± 0.06	2.462PheThr: 2.462 ± 0.045	2.593PheVal: 2.593 ± 0.045	0.654PheTrp: 0.654 ± 0.021	1.694PheTyr: 1.694 ± 0.036	0.0PheXaa: 0.0 ± 0.0
Gly	5.06GlyAla: 5.06 ± 0.062	0.648GlyCys: 0.648 ± 0.022	4.292GlyAsp: 4.292 ± 0.075	5.424GlyGlu: 5.424 ± 0.063	3.35GlyPhe: 3.35 ± 0.053	5.757GlyGly: 5.757 ± 0.085	1.549GlyHis: 1.549 ± 0.039	5.367GlyIle: 5.367 ± 0.067	3.719GlyLys: 3.719 ± 0.057	6.557GlyLeu: 6.557 ± 0.074	2.124GlyMet: 2.124 ± 0.036	3.283GlyAsn: 3.283 ± 0.065	2.275GlyPro: 2.275 ± 0.042	2.71GlyGln: 2.71 ± 0.044	3.982GlyArg: 3.982 ± 0.067	4.872GlySer: 4.872 ± 0.072	4.517GlyThr: 4.517 ± 0.069	4.614GlyVal: 4.614 ± 0.067	1.24GlyTrp: 1.24 ± 0.033	3.255GlyTyr: 3.255 ± 0.054	0.0GlyXaa: 0.0 ± 0.0
His	1.392HisAla: 1.392 ± 0.033	0.198HisCys: 0.198 ± 0.012	1.052HisAsp: 1.052 ± 0.031	1.334HisGlu: 1.334 ± 0.034	1.093HisPhe: 1.093 ± 0.029	1.464HisGly: 1.464 ± 0.036	0.639HisHis: 0.639 ± 0.023	1.454HisIle: 1.454 ± 0.029	0.937HisLys: 0.937 ± 0.025	2.037HisLeu: 2.037 ± 0.037	0.488HisMet: 0.488 ± 0.02	0.911HisAsn: 0.911 ± 0.025	1.412HisPro: 1.412 ± 0.032	0.802HisGln: 0.802 ± 0.022	1.246HisArg: 1.246 ± 0.034	1.347HisSer: 1.347 ± 0.029	1.168HisThr: 1.168 ± 0.033	1.099HisVal: 1.099 ± 0.025	0.353HisTrp: 0.353 ± 0.016	0.906HisTyr: 0.906 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	4.887IleAla: 4.887 ± 0.065	0.518IleCys: 0.518 ± 0.024	4.316IleAsp: 4.316 ± 0.056	4.785IleGlu: 4.785 ± 0.078	2.637IlePhe: 2.637 ± 0.047	4.774IleGly: 4.774 ± 0.06	1.371IleHis: 1.371 ± 0.031	4.08IleIle: 4.08 ± 0.075	3.047IleLys: 3.047 ± 0.052	5.556IleLeu: 5.556 ± 0.074	1.318IleMet: 1.318 ± 0.031	3.035IleAsn: 3.035 ± 0.052	3.21IlePro: 3.21 ± 0.046	2.241IleGln: 2.241 ± 0.041	3.882IleArg: 3.882 ± 0.06	4.784IleSer: 4.784 ± 0.055	3.989IleThr: 3.989 ± 0.05	3.726IleVal: 3.726 ± 0.053	0.729IleTrp: 0.729 ± 0.024	2.191IleTyr: 2.191 ± 0.039	0.0IleXaa: 0.0 ± 0.0
Lys	3.72LysAla: 3.72 ± 0.061	0.211LysCys: 0.211 ± 0.011	2.577LysAsp: 2.577 ± 0.047	4.412LysGlu: 4.412 ± 0.072	1.482LysPhe: 1.482 ± 0.034	3.252LysGly: 3.252 ± 0.048	1.014LysHis: 1.014 ± 0.025	3.269LysIle: 3.269 ± 0.053	3.891LysLys: 3.891 ± 0.069	4.261LysLeu: 4.261 ± 0.06	1.3LysMet: 1.3 ± 0.027	2.521LysAsn: 2.521 ± 0.048	1.949LysPro: 1.949 ± 0.037	2.146LysGln: 2.146 ± 0.039	2.786LysArg: 2.786 ± 0.047	2.816LysSer: 2.816 ± 0.045	2.775LysThr: 2.775 ± 0.044	3.155LysVal: 3.155 ± 0.047	0.614LysTrp: 0.614 ± 0.021	1.783LysTyr: 1.783 ± 0.036	0.0LysXaa: 0.0 ± 0.0
Leu	6.634LeuAla: 6.634 ± 0.094	0.647LeuCys: 0.647 ± 0.021	5.509LeuAsp: 5.509 ± 0.064	6.481LeuGlu: 6.481 ± 0.078	4.426LeuPhe: 4.426 ± 0.072	6.317LeuGly: 6.317 ± 0.073	1.837LeuHis: 1.837 ± 0.039	5.542LeuIle: 5.542 ± 0.077	5.014LeuLys: 5.014 ± 0.07	9.148LeuLeu: 9.148 ± 0.125	2.161LeuMet: 2.161 ± 0.042	4.245LeuAsn: 4.245 ± 0.055	4.203LeuPro: 4.203 ± 0.059	3.697LeuGln: 3.697 ± 0.05	4.891LeuArg: 4.891 ± 0.06	6.943LeuSer: 6.943 ± 0.078	5.165LeuThr: 5.165 ± 0.069	5.511LeuVal: 5.511 ± 0.074	1.119LeuTrp: 1.119 ± 0.033	3.194LeuTyr: 3.194 ± 0.049	0.0LeuXaa: 0.0 ± 0.0
Met	1.887MetAla: 1.887 ± 0.039	0.107MetCys: 0.107 ± 0.008	1.626MetAsp: 1.626 ± 0.032	1.814MetGlu: 1.814 ± 0.035	0.758MetPhe: 0.758 ± 0.027	1.794MetGly: 1.794 ± 0.038	0.485MetHis: 0.485 ± 0.017	1.541MetIle: 1.541 ± 0.04	1.596MetLys: 1.596 ± 0.032	2.172MetLeu: 2.172 ± 0.041	0.701MetMet: 0.701 ± 0.028	1.284MetAsn: 1.284 ± 0.031	1.073MetPro: 1.073 ± 0.026	0.939MetGln: 0.939 ± 0.025	1.156MetArg: 1.156 ± 0.028	1.51MetSer: 1.51 ± 0.033	1.214MetThr: 1.214 ± 0.029	1.582MetVal: 1.582 ± 0.033	0.224MetTrp: 0.224 ± 0.013	0.632MetTyr: 0.632 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	2.937AsnAla: 2.937 ± 0.047	0.272AsnCys: 0.272 ± 0.014	2.352AsnAsp: 2.352 ± 0.048	2.91AsnGlu: 2.91 ± 0.049	1.871AsnPhe: 1.871 ± 0.038	3.172AsnGly: 3.172 ± 0.058	1.006AsnHis: 1.006 ± 0.027	3.411AsnIle: 3.411 ± 0.058	2.236AsnLys: 2.236 ± 0.04	3.889AsnLeu: 3.889 ± 0.056	1.128AsnMet: 1.128 ± 0.026	2.291AsnAsn: 2.291 ± 0.054	2.5AsnPro: 2.5 ± 0.043	1.691AsnGln: 1.691 ± 0.041	2.847AsnArg: 2.847 ± 0.046	2.629AsnSer: 2.629 ± 0.049	2.426AsnThr: 2.426 ± 0.045	2.614AsnVal: 2.614 ± 0.052	0.594AsnTrp: 0.594 ± 0.023	1.895AsnTyr: 1.895 ± 0.045	0.0AsnXaa: 0.0 ± 0.0
Pro	3.057ProAla: 3.057 ± 0.047	0.237ProCys: 0.237 ± 0.013	3.602ProAsp: 3.602 ± 0.057	4.095ProGlu: 4.095 ± 0.055	1.935ProPhe: 1.935 ± 0.041	3.653ProGly: 3.653 ± 0.055	0.921ProHis: 0.921 ± 0.024	2.224ProIle: 2.224 ± 0.043	1.582ProLys: 1.582 ± 0.039	3.632ProLeu: 3.632 ± 0.057	0.871ProMet: 0.871 ± 0.024	1.652ProAsn: 1.652 ± 0.034	1.64ProPro: 1.64 ± 0.037	1.384ProGln: 1.384 ± 0.029	1.922ProArg: 1.922 ± 0.045	2.591ProSer: 2.591 ± 0.048	1.934ProThr: 1.934 ± 0.038	3.4ProVal: 3.4 ± 0.046	0.531ProTrp: 0.531 ± 0.022	1.537ProTyr: 1.537 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	2.944GlnAla: 2.944 ± 0.05	0.182GlnCys: 0.182 ± 0.011	1.861GlnAsp: 1.861 ± 0.035	2.851GlnGlu: 2.851 ± 0.049	1.577GlnPhe: 1.577 ± 0.036	2.237GlnGly: 2.237 ± 0.038	0.869GlnHis: 0.869 ± 0.024	2.226GlnIle: 2.226 ± 0.038	2.319GlnLys: 2.319 ± 0.046	3.96GlnLeu: 3.96 ± 0.058	0.982GlnMet: 0.982 ± 0.027	1.896GlnAsn: 1.896 ± 0.041	1.705GlnPro: 1.705 ± 0.03	2.443GlnGln: 2.443 ± 0.047	2.078GlnArg: 2.078 ± 0.043	2.55GlnSer: 2.55 ± 0.049	2.077GlnThr: 2.077 ± 0.038	2.334GlnVal: 2.334 ± 0.043	0.606GlnTrp: 0.606 ± 0.02	1.34GlnTyr: 1.34 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	3.496ArgAla: 3.496 ± 0.049	0.333ArgCys: 0.333 ± 0.017	3.181ArgAsp: 3.181 ± 0.047	4.755ArgGlu: 4.755 ± 0.069	2.53ArgPhe: 2.53 ± 0.046	3.428ArgGly: 3.428 ± 0.053	1.169ArgHis: 1.169 ± 0.029	3.739ArgIle: 3.739 ± 0.053	3.094ArgLys: 3.094 ± 0.053	5.103ArgLeu: 5.103 ± 0.068	1.379ArgMet: 1.379 ± 0.029	2.548ArgAsn: 2.548 ± 0.049	2.073ArgPro: 2.073 ± 0.043	2.415ArgGln: 2.415 ± 0.045	3.11ArgArg: 3.11 ± 0.05	3.435ArgSer: 3.435 ± 0.054	2.735ArgThr: 2.735 ± 0.046	3.159ArgVal: 3.159 ± 0.051	0.889ArgTrp: 0.889 ± 0.026	2.4ArgTyr: 2.4 ± 0.054	0.0ArgXaa: 0.0 ± 0.0
Ser	4.368SerAla: 4.368 ± 0.056	0.52SerCys: 0.52 ± 0.021	4.143SerAsp: 4.143 ± 0.057	4.462SerGlu: 4.462 ± 0.056	3.172SerPhe: 3.172 ± 0.051	5.608SerGly: 5.608 ± 0.072	1.303SerHis: 1.303 ± 0.032	4.041SerIle: 4.041 ± 0.056	2.742SerLys: 2.742 ± 0.052	6.232SerLeu: 6.232 ± 0.068	1.486SerMet: 1.486 ± 0.033	2.702SerAsn: 2.702 ± 0.046	2.614SerPro: 2.614 ± 0.045	2.174SerGln: 2.174 ± 0.04	3.524SerArg: 3.524 ± 0.057	4.5SerSer: 4.5 ± 0.065	3.516SerThr: 3.516 ± 0.053	4.295SerVal: 4.295 ± 0.054	0.952SerTrp: 0.952 ± 0.025	2.539SerTyr: 2.539 ± 0.049	0.0SerXaa: 0.0 ± 0.0
Thr	4.025ThrAla: 4.025 ± 0.059	0.331ThrCys: 0.331 ± 0.015	3.584ThrAsp: 3.584 ± 0.053	3.63ThrGlu: 3.63 ± 0.053	2.538ThrPhe: 2.538 ± 0.044	5.007ThrGly: 5.007 ± 0.073	1.113ThrHis: 1.113 ± 0.03	3.83ThrIle: 3.83 ± 0.058	2.059ThrLys: 2.059 ± 0.038	5.322ThrLeu: 5.322 ± 0.075	1.17ThrMet: 1.17 ± 0.031	2.111ThrAsn: 2.111 ± 0.044	2.541ThrPro: 2.541 ± 0.043	1.717ThrGln: 1.717 ± 0.043	2.513ThrArg: 2.513 ± 0.044	3.458ThrSer: 3.458 ± 0.052	3.057ThrThr: 3.057 ± 0.055	3.884ThrVal: 3.884 ± 0.057	0.581ThrTrp: 0.581 ± 0.019	2.011ThrTyr: 2.011 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	4.559ValAla: 4.559 ± 0.062	0.471ValCys: 0.471 ± 0.02	4.032ValAsp: 4.032 ± 0.051	4.683ValGlu: 4.683 ± 0.062	2.692ValPhe: 2.692 ± 0.04	4.452ValGly: 4.452 ± 0.068	1.243ValHis: 1.243 ± 0.03	4.232ValIle: 4.232 ± 0.062	2.842ValLys: 2.842 ± 0.045	5.767ValLeu: 5.767 ± 0.069	1.566ValMet: 1.566 ± 0.036	2.785ValAsn: 2.785 ± 0.046	2.795ValPro: 2.795 ± 0.043	2.166ValGln: 2.166 ± 0.039	3.465ValArg: 3.465 ± 0.051	4.489ValSer: 4.489 ± 0.064	3.806ValThr: 3.806 ± 0.057	4.271ValVal: 4.271 ± 0.064	0.711ValTrp: 0.711 ± 0.024	2.087ValTyr: 2.087 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	0.843TrpAla: 0.843 ± 0.023	0.098TrpCys: 0.098 ± 0.007	0.774TrpAsp: 0.774 ± 0.024	0.944TrpGlu: 0.944 ± 0.028	0.555TrpPhe: 0.555 ± 0.023	0.998TrpGly: 0.998 ± 0.026	0.353TrpHis: 0.353 ± 0.018	0.913TrpIle: 0.913 ± 0.026	0.747TrpLys: 0.747 ± 0.026	1.246TrpLeu: 1.246 ± 0.032	0.437TrpMet: 0.437 ± 0.019	0.693TrpAsn: 0.693 ± 0.022	0.513TrpPro: 0.513 ± 0.02	0.618TrpGln: 0.618 ± 0.022	0.714TrpArg: 0.714 ± 0.024	0.855TrpSer: 0.855 ± 0.027	0.73TrpThr: 0.73 ± 0.021	0.769TrpVal: 0.769 ± 0.026	0.251TrpTrp: 0.251 ± 0.013	0.515TrpTyr: 0.515 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.4TyrAla: 2.4 ± 0.048	0.281TyrCys: 0.281 ± 0.014	2.383TyrAsp: 2.383 ± 0.048	2.674TyrGlu: 2.674 ± 0.048	1.698TyrPhe: 1.698 ± 0.04	2.86TyrGly: 2.86 ± 0.048	0.906TyrHis: 0.906 ± 0.025	2.144TyrIle: 2.144 ± 0.044	1.637TyrLys: 1.637 ± 0.034	3.606TyrLeu: 3.606 ± 0.049	0.72TyrMet: 0.72 ± 0.023	1.755TyrAsn: 1.755 ± 0.039	1.755TyrPro: 1.755 ± 0.037	1.557TyrGln: 1.557 ± 0.034	2.48TyrArg: 2.48 ± 0.048	2.43TyrSer: 2.43 ± 0.048	1.942TyrThr: 1.942 ± 0.04	1.978TyrVal: 1.978 ± 0.039	0.583TyrTrp: 0.583 ± 0.023	1.574TyrTyr: 1.574 ± 0.04	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4289 proteins (1460705 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---