Amino acid dipepetide frequency for Hubei picorna-like virus 28

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.362AlaAla: 3.362 ± 0.0
1.681AlaCys: 1.681 ± 0.0
2.69AlaAsp: 2.69 ± 0.0
4.707AlaGlu: 4.707 ± 0.0
2.354AlaPhe: 2.354 ± 0.0
3.362AlaGly: 3.362 ± 0.0
0.336AlaHis: 0.336 ± 0.0
5.38AlaIle: 5.38 ± 0.0
2.354AlaLys: 2.354 ± 0.0
3.026AlaLeu: 3.026 ± 0.0
2.017AlaMet: 2.017 ± 0.0
2.69AlaAsn: 2.69 ± 0.0
2.354AlaPro: 2.354 ± 0.0
1.345AlaGln: 1.345 ± 0.0
3.699AlaArg: 3.699 ± 0.0
8.742AlaSer: 8.742 ± 0.0
2.354AlaThr: 2.354 ± 0.0
4.035AlaVal: 4.035 ± 0.0
1.009AlaTrp: 1.009 ± 0.0
5.38AlaTyr: 5.38 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
2.017CysAla: 2.017 ± 0.0
0.672CysCys: 0.672 ± 0.0
2.017CysAsp: 2.017 ± 0.0
1.681CysGlu: 1.681 ± 0.0
0.672CysPhe: 0.672 ± 0.0
1.345CysGly: 1.345 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.672CysIle: 0.672 ± 0.0
1.345CysLys: 1.345 ± 0.0
2.69CysLeu: 2.69 ± 0.0
0.336CysMet: 0.336 ± 0.0
1.681CysAsn: 1.681 ± 0.0
1.009CysPro: 1.009 ± 0.0
1.009CysGln: 1.009 ± 0.0
2.017CysArg: 2.017 ± 0.0
1.681CysSer: 1.681 ± 0.0
0.0CysThr: 0.0 ± 0.0
1.681CysVal: 1.681 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.672CysTyr: 0.672 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.707AspAla: 4.707 ± 0.0
1.009AspCys: 1.009 ± 0.0
2.354AspAsp: 2.354 ± 0.0
4.035AspGlu: 4.035 ± 0.0
3.362AspPhe: 3.362 ± 0.0
3.699AspGly: 3.699 ± 0.0
1.009AspHis: 1.009 ± 0.0
2.017AspIle: 2.017 ± 0.0
3.026AspLys: 3.026 ± 0.0
5.716AspLeu: 5.716 ± 0.0
1.009AspMet: 1.009 ± 0.0
1.345AspAsn: 1.345 ± 0.0
2.354AspPro: 2.354 ± 0.0
2.017AspGln: 2.017 ± 0.0
2.354AspArg: 2.354 ± 0.0
3.026AspSer: 3.026 ± 0.0
1.681AspThr: 1.681 ± 0.0
2.69AspVal: 2.69 ± 0.0
1.009AspTrp: 1.009 ± 0.0
3.026AspTyr: 3.026 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
2.69GluAla: 2.69 ± 0.0
2.354GluCys: 2.354 ± 0.0
4.371GluAsp: 4.371 ± 0.0
4.035GluGlu: 4.035 ± 0.0
3.026GluPhe: 3.026 ± 0.0
2.69GluGly: 2.69 ± 0.0
0.672GluHis: 0.672 ± 0.0
4.707GluIle: 4.707 ± 0.0
2.69GluLys: 2.69 ± 0.0
5.044GluLeu: 5.044 ± 0.0
2.354GluMet: 2.354 ± 0.0
3.362GluAsn: 3.362 ± 0.0
2.354GluPro: 2.354 ± 0.0
3.026GluGln: 3.026 ± 0.0
2.017GluArg: 2.017 ± 0.0
2.354GluSer: 2.354 ± 0.0
2.69GluThr: 2.69 ± 0.0
5.716GluVal: 5.716 ± 0.0
1.345GluTrp: 1.345 ± 0.0
2.354GluTyr: 2.354 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.017PheAla: 2.017 ± 0.0
1.009PheCys: 1.009 ± 0.0
3.362PheAsp: 3.362 ± 0.0
3.026PheGlu: 3.026 ± 0.0
1.345PhePhe: 1.345 ± 0.0
3.362PheGly: 3.362 ± 0.0
0.336PheHis: 0.336 ± 0.0
4.371PheIle: 4.371 ± 0.0
4.035PheLys: 4.035 ± 0.0
1.681PheLeu: 1.681 ± 0.0
3.026PheMet: 3.026 ± 0.0
4.707PheAsn: 4.707 ± 0.0
2.017PhePro: 2.017 ± 0.0
2.69PheGln: 2.69 ± 0.0
2.354PheArg: 2.354 ± 0.0
3.026PheSer: 3.026 ± 0.0
5.38PheThr: 5.38 ± 0.0
2.017PheVal: 2.017 ± 0.0
1.345PheTrp: 1.345 ± 0.0
1.009PheTyr: 1.009 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.371GlyAla: 4.371 ± 0.0
1.009GlyCys: 1.009 ± 0.0
3.699GlyAsp: 3.699 ± 0.0
3.026GlyGlu: 3.026 ± 0.0
2.354GlyPhe: 2.354 ± 0.0
2.354GlyGly: 2.354 ± 0.0
1.345GlyHis: 1.345 ± 0.0
5.044GlyIle: 5.044 ± 0.0
4.707GlyLys: 4.707 ± 0.0
2.69GlyLeu: 2.69 ± 0.0
2.017GlyMet: 2.017 ± 0.0
1.681GlyAsn: 1.681 ± 0.0
3.362GlyPro: 3.362 ± 0.0
1.345GlyGln: 1.345 ± 0.0
2.69GlyArg: 2.69 ± 0.0
4.707GlySer: 4.707 ± 0.0
4.035GlyThr: 4.035 ± 0.0
2.69GlyVal: 2.69 ± 0.0
0.0GlyTrp: 0.0 ± 0.0
2.017GlyTyr: 2.017 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
3.026HisAla: 3.026 ± 0.0
1.345HisCys: 1.345 ± 0.0
0.672HisAsp: 0.672 ± 0.0
1.009HisGlu: 1.009 ± 0.0
1.009HisPhe: 1.009 ± 0.0
2.354HisGly: 2.354 ± 0.0
1.009HisHis: 1.009 ± 0.0
1.345HisIle: 1.345 ± 0.0
1.009HisLys: 1.009 ± 0.0
2.354HisLeu: 2.354 ± 0.0
0.336HisMet: 0.336 ± 0.0
2.017HisAsn: 2.017 ± 0.0
2.354HisPro: 2.354 ± 0.0
0.336HisGln: 0.336 ± 0.0
0.672HisArg: 0.672 ± 0.0
1.009HisSer: 1.009 ± 0.0
0.672HisThr: 0.672 ± 0.0
2.017HisVal: 2.017 ± 0.0
0.336HisTrp: 0.336 ± 0.0
1.009HisTyr: 1.009 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
5.716IleAla: 5.716 ± 0.0
2.017IleCys: 2.017 ± 0.0
3.026IleAsp: 3.026 ± 0.0
2.017IleGlu: 2.017 ± 0.0
3.026IlePhe: 3.026 ± 0.0
1.681IleGly: 1.681 ± 0.0
0.672IleHis: 0.672 ± 0.0
3.362IleIle: 3.362 ± 0.0
2.69IleLys: 2.69 ± 0.0
5.044IleLeu: 5.044 ± 0.0
2.017IleMet: 2.017 ± 0.0
3.362IleAsn: 3.362 ± 0.0
3.026IlePro: 3.026 ± 0.0
2.017IleGln: 2.017 ± 0.0
2.354IleArg: 2.354 ± 0.0
3.362IleSer: 3.362 ± 0.0
2.017IleThr: 2.017 ± 0.0
6.389IleVal: 6.389 ± 0.0
1.009IleTrp: 1.009 ± 0.0
3.026IleTyr: 3.026 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
1.681LysAla: 1.681 ± 0.0
0.672LysCys: 0.672 ± 0.0
2.017LysAsp: 2.017 ± 0.0
4.035LysGlu: 4.035 ± 0.0
4.371LysPhe: 4.371 ± 0.0
2.69LysGly: 2.69 ± 0.0
2.69LysHis: 2.69 ± 0.0
2.69LysIle: 2.69 ± 0.0
2.017LysLys: 2.017 ± 0.0
3.362LysLeu: 3.362 ± 0.0
0.672LysMet: 0.672 ± 0.0
4.371LysAsn: 4.371 ± 0.0
4.035LysPro: 4.035 ± 0.0
2.354LysGln: 2.354 ± 0.0
3.026LysArg: 3.026 ± 0.0
5.38LysSer: 5.38 ± 0.0
1.681LysThr: 1.681 ± 0.0
3.362LysVal: 3.362 ± 0.0
1.345LysTrp: 1.345 ± 0.0
1.345LysTyr: 1.345 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
7.734LeuAla: 7.734 ± 0.0
2.354LeuCys: 2.354 ± 0.0
3.699LeuAsp: 3.699 ± 0.0
6.052LeuGlu: 6.052 ± 0.0
4.707LeuPhe: 4.707 ± 0.0
4.371LeuGly: 4.371 ± 0.0
2.354LeuHis: 2.354 ± 0.0
2.354LeuIle: 2.354 ± 0.0
5.38LeuLys: 5.38 ± 0.0
6.725LeuLeu: 6.725 ± 0.0
2.354LeuMet: 2.354 ± 0.0
5.38LeuAsn: 5.38 ± 0.0
3.699LeuPro: 3.699 ± 0.0
2.69LeuGln: 2.69 ± 0.0
5.716LeuArg: 5.716 ± 0.0
5.38LeuSer: 5.38 ± 0.0
2.017LeuThr: 2.017 ± 0.0
6.052LeuVal: 6.052 ± 0.0
0.672LeuTrp: 0.672 ± 0.0
2.017LeuTyr: 2.017 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
1.681MetAla: 1.681 ± 0.0
1.009MetCys: 1.009 ± 0.0
1.681MetAsp: 1.681 ± 0.0
1.681MetGlu: 1.681 ± 0.0
2.017MetPhe: 2.017 ± 0.0
1.009MetGly: 1.009 ± 0.0
1.009MetHis: 1.009 ± 0.0
1.345MetIle: 1.345 ± 0.0
0.336MetLys: 0.336 ± 0.0
2.354MetLeu: 2.354 ± 0.0
1.009MetMet: 1.009 ± 0.0
1.009MetAsn: 1.009 ± 0.0
0.672MetPro: 0.672 ± 0.0
0.672MetGln: 0.672 ± 0.0
2.354MetArg: 2.354 ± 0.0
3.362MetSer: 3.362 ± 0.0
1.681MetThr: 1.681 ± 0.0
0.672MetVal: 0.672 ± 0.0
0.336MetTrp: 0.336 ± 0.0
0.672MetTyr: 0.672 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.017AsnAla: 2.017 ± 0.0
1.345AsnCys: 1.345 ± 0.0
3.362AsnAsp: 3.362 ± 0.0
2.69AsnGlu: 2.69 ± 0.0
4.035AsnPhe: 4.035 ± 0.0
3.026AsnGly: 3.026 ± 0.0
2.017AsnHis: 2.017 ± 0.0
5.716AsnIle: 5.716 ± 0.0
3.699AsnLys: 3.699 ± 0.0
3.026AsnLeu: 3.026 ± 0.0
1.009AsnMet: 1.009 ± 0.0
3.699AsnAsn: 3.699 ± 0.0
5.044AsnPro: 5.044 ± 0.0
0.336AsnGln: 0.336 ± 0.0
2.017AsnArg: 2.017 ± 0.0
3.699AsnSer: 3.699 ± 0.0
2.69AsnThr: 2.69 ± 0.0
5.38AsnVal: 5.38 ± 0.0
1.345AsnTrp: 1.345 ± 0.0
3.362AsnTyr: 3.362 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.026ProAla: 3.026 ± 0.0
1.681ProCys: 1.681 ± 0.0
2.017ProAsp: 2.017 ± 0.0
2.69ProGlu: 2.69 ± 0.0
3.026ProPhe: 3.026 ± 0.0
1.681ProGly: 1.681 ± 0.0
1.009ProHis: 1.009 ± 0.0
2.69ProIle: 2.69 ± 0.0
3.699ProLys: 3.699 ± 0.0
4.371ProLeu: 4.371 ± 0.0
1.345ProMet: 1.345 ± 0.0
4.035ProAsn: 4.035 ± 0.0
1.345ProPro: 1.345 ± 0.0
2.354ProGln: 2.354 ± 0.0
1.345ProArg: 1.345 ± 0.0
3.362ProSer: 3.362 ± 0.0
3.362ProThr: 3.362 ± 0.0
4.035ProVal: 4.035 ± 0.0
1.009ProTrp: 1.009 ± 0.0
1.681ProTyr: 1.681 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.69GlnAla: 2.69 ± 0.0
0.336GlnCys: 0.336 ± 0.0
0.672GlnAsp: 0.672 ± 0.0
2.017GlnGlu: 2.017 ± 0.0
2.354GlnPhe: 2.354 ± 0.0
2.354GlnGly: 2.354 ± 0.0
2.017GlnHis: 2.017 ± 0.0
1.009GlnIle: 1.009 ± 0.0
1.681GlnLys: 1.681 ± 0.0
2.69GlnLeu: 2.69 ± 0.0
1.345GlnMet: 1.345 ± 0.0
1.345GlnAsn: 1.345 ± 0.0
1.009GlnPro: 1.009 ± 0.0
2.69GlnGln: 2.69 ± 0.0
1.681GlnArg: 1.681 ± 0.0
3.026GlnSer: 3.026 ± 0.0
2.354GlnThr: 2.354 ± 0.0
2.69GlnVal: 2.69 ± 0.0
1.345GlnTrp: 1.345 ± 0.0
1.345GlnTyr: 1.345 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.354ArgAla: 2.354 ± 0.0
0.672ArgCys: 0.672 ± 0.0
3.699ArgAsp: 3.699 ± 0.0
3.362ArgGlu: 3.362 ± 0.0
2.69ArgPhe: 2.69 ± 0.0
4.035ArgGly: 4.035 ± 0.0
1.009ArgHis: 1.009 ± 0.0
2.017ArgIle: 2.017 ± 0.0
2.017ArgLys: 2.017 ± 0.0
6.725ArgLeu: 6.725 ± 0.0
1.009ArgMet: 1.009 ± 0.0
4.035ArgAsn: 4.035 ± 0.0
1.345ArgPro: 1.345 ± 0.0
1.681ArgGln: 1.681 ± 0.0
4.035ArgArg: 4.035 ± 0.0
1.681ArgSer: 1.681 ± 0.0
1.345ArgThr: 1.345 ± 0.0
4.035ArgVal: 4.035 ± 0.0
0.0ArgTrp: 0.0 ± 0.0
3.026ArgTyr: 3.026 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
4.707SerAla: 4.707 ± 0.0
0.336SerCys: 0.336 ± 0.0
3.362SerAsp: 3.362 ± 0.0
5.044SerGlu: 5.044 ± 0.0
3.362SerPhe: 3.362 ± 0.0
3.026SerGly: 3.026 ± 0.0
1.681SerHis: 1.681 ± 0.0
3.699SerIle: 3.699 ± 0.0
4.035SerLys: 4.035 ± 0.0
5.38SerLeu: 5.38 ± 0.0
1.345SerMet: 1.345 ± 0.0
5.716SerAsn: 5.716 ± 0.0
3.026SerPro: 3.026 ± 0.0
3.026SerGln: 3.026 ± 0.0
3.026SerArg: 3.026 ± 0.0
8.07SerSer: 8.07 ± 0.0
2.354SerThr: 2.354 ± 0.0
6.725SerVal: 6.725 ± 0.0
2.354SerTrp: 2.354 ± 0.0
3.362SerTyr: 3.362 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
1.681ThrAla: 1.681 ± 0.0
0.672ThrCys: 0.672 ± 0.0
2.69ThrAsp: 2.69 ± 0.0
1.681ThrGlu: 1.681 ± 0.0
2.354ThrPhe: 2.354 ± 0.0
4.371ThrGly: 4.371 ± 0.0
1.345ThrHis: 1.345 ± 0.0
3.362ThrIle: 3.362 ± 0.0
2.69ThrLys: 2.69 ± 0.0
4.371ThrLeu: 4.371 ± 0.0
0.336ThrMet: 0.336 ± 0.0
1.009ThrAsn: 1.009 ± 0.0
2.354ThrPro: 2.354 ± 0.0
2.69ThrGln: 2.69 ± 0.0
1.681ThrArg: 1.681 ± 0.0
4.371ThrSer: 4.371 ± 0.0
2.017ThrThr: 2.017 ± 0.0
2.69ThrVal: 2.69 ± 0.0
0.672ThrTrp: 0.672 ± 0.0
1.345ThrTyr: 1.345 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
4.035ValAla: 4.035 ± 0.0
0.672ValCys: 0.672 ± 0.0
3.699ValAsp: 3.699 ± 0.0
4.707ValGlu: 4.707 ± 0.0
2.69ValPhe: 2.69 ± 0.0
3.699ValGly: 3.699 ± 0.0
3.362ValHis: 3.362 ± 0.0
2.69ValIle: 2.69 ± 0.0
2.69ValLys: 2.69 ± 0.0
8.742ValLeu: 8.742 ± 0.0
0.672ValMet: 0.672 ± 0.0
4.707ValAsn: 4.707 ± 0.0
5.716ValPro: 5.716 ± 0.0
2.69ValGln: 2.69 ± 0.0
3.699ValArg: 3.699 ± 0.0
4.035ValSer: 4.035 ± 0.0
3.362ValThr: 3.362 ± 0.0
4.707ValVal: 4.707 ± 0.0
2.354ValTrp: 2.354 ± 0.0
3.026ValTyr: 3.026 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.336TrpAla: 0.336 ± 0.0
0.336TrpCys: 0.336 ± 0.0
1.009TrpAsp: 1.009 ± 0.0
0.672TrpGlu: 0.672 ± 0.0
0.672TrpPhe: 0.672 ± 0.0
1.009TrpGly: 1.009 ± 0.0
1.681TrpHis: 1.681 ± 0.0
0.336TrpIle: 0.336 ± 0.0
0.672TrpLys: 0.672 ± 0.0
2.69TrpLeu: 2.69 ± 0.0
1.009TrpMet: 1.009 ± 0.0
2.354TrpAsn: 2.354 ± 0.0
1.009TrpPro: 1.009 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.345TrpArg: 1.345 ± 0.0
0.336TrpSer: 0.336 ± 0.0
1.345TrpThr: 1.345 ± 0.0
1.681TrpVal: 1.681 ± 0.0
0.672TrpTrp: 0.672 ± 0.0
0.672TrpTyr: 0.672 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.026TyrAla: 3.026 ± 0.0
2.017TyrCys: 2.017 ± 0.0
1.345TyrAsp: 1.345 ± 0.0
2.017TyrGlu: 2.017 ± 0.0
2.69TyrPhe: 2.69 ± 0.0
3.026TyrGly: 3.026 ± 0.0
0.336TyrHis: 0.336 ± 0.0
3.026TyrIle: 3.026 ± 0.0
3.026TyrLys: 3.026 ± 0.0
3.026TyrLeu: 3.026 ± 0.0
1.009TyrMet: 1.009 ± 0.0
1.009TyrAsn: 1.009 ± 0.0
1.681TyrPro: 1.681 ± 0.0
1.681TyrGln: 1.681 ± 0.0
2.69TyrArg: 2.69 ± 0.0
3.026TyrSer: 3.026 ± 0.0
1.345TyrThr: 1.345 ± 0.0
2.69TyrVal: 2.69 ± 0.0
1.681TyrTrp: 1.681 ± 0.0
2.69TyrTyr: 2.69 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2975 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski