Amino acid dipepetide frequency for Wuhan coneheads virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.985AlaAla: 1.985 ± 0.0
0.993AlaCys: 0.993 ± 0.0
2.647AlaAsp: 2.647 ± 0.0
2.647AlaGlu: 2.647 ± 0.0
1.655AlaPhe: 1.655 ± 0.0
2.978AlaGly: 2.978 ± 0.0
0.993AlaHis: 0.993 ± 0.0
3.64AlaIle: 3.64 ± 0.0
3.309AlaLys: 3.309 ± 0.0
4.302AlaLeu: 4.302 ± 0.0
0.993AlaMet: 0.993 ± 0.0
0.993AlaAsn: 0.993 ± 0.0
1.985AlaPro: 1.985 ± 0.0
0.993AlaGln: 0.993 ± 0.0
3.309AlaArg: 3.309 ± 0.0
3.309AlaSer: 3.309 ± 0.0
3.309AlaThr: 3.309 ± 0.0
3.309AlaVal: 3.309 ± 0.0
0.993AlaTrp: 0.993 ± 0.0
2.647AlaTyr: 2.647 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.993CysAla: 0.993 ± 0.0
0.331CysCys: 0.331 ± 0.0
0.331CysAsp: 0.331 ± 0.0
0.331CysGlu: 0.331 ± 0.0
0.662CysPhe: 0.662 ± 0.0
1.324CysGly: 1.324 ± 0.0
0.662CysHis: 0.662 ± 0.0
0.993CysIle: 0.993 ± 0.0
2.316CysLys: 2.316 ± 0.0
2.978CysLeu: 2.978 ± 0.0
0.331CysMet: 0.331 ± 0.0
0.662CysAsn: 0.662 ± 0.0
0.331CysPro: 0.331 ± 0.0
0.662CysGln: 0.662 ± 0.0
0.662CysArg: 0.662 ± 0.0
2.647CysSer: 2.647 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.331CysVal: 0.331 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.662CysTyr: 0.662 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.978AspAla: 2.978 ± 0.0
1.985AspCys: 1.985 ± 0.0
3.64AspAsp: 3.64 ± 0.0
3.971AspGlu: 3.971 ± 0.0
3.309AspPhe: 3.309 ± 0.0
2.978AspGly: 2.978 ± 0.0
0.331AspHis: 0.331 ± 0.0
6.287AspIle: 6.287 ± 0.0
6.618AspLys: 6.618 ± 0.0
2.647AspLeu: 2.647 ± 0.0
0.331AspMet: 0.331 ± 0.0
2.978AspAsn: 2.978 ± 0.0
2.316AspPro: 2.316 ± 0.0
1.324AspGln: 1.324 ± 0.0
1.985AspArg: 1.985 ± 0.0
5.295AspSer: 5.295 ± 0.0
3.971AspThr: 3.971 ± 0.0
2.316AspVal: 2.316 ± 0.0
0.662AspTrp: 0.662 ± 0.0
1.655AspTyr: 1.655 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
4.633GluAla: 4.633 ± 0.0
1.324GluCys: 1.324 ± 0.0
2.978GluAsp: 2.978 ± 0.0
3.309GluGlu: 3.309 ± 0.0
2.978GluPhe: 2.978 ± 0.0
5.295GluGly: 5.295 ± 0.0
0.993GluHis: 0.993 ± 0.0
4.964GluIle: 4.964 ± 0.0
4.633GluLys: 4.633 ± 0.0
5.956GluLeu: 5.956 ± 0.0
0.993GluMet: 0.993 ± 0.0
4.302GluAsn: 4.302 ± 0.0
2.647GluPro: 2.647 ± 0.0
2.647GluGln: 2.647 ± 0.0
2.978GluArg: 2.978 ± 0.0
3.309GluSer: 3.309 ± 0.0
2.647GluThr: 2.647 ± 0.0
1.985GluVal: 1.985 ± 0.0
0.993GluTrp: 0.993 ± 0.0
3.309GluTyr: 3.309 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.978PheAla: 2.978 ± 0.0
0.662PheCys: 0.662 ± 0.0
2.978PheAsp: 2.978 ± 0.0
5.956PheGlu: 5.956 ± 0.0
1.655PhePhe: 1.655 ± 0.0
0.993PheGly: 0.993 ± 0.0
0.662PheHis: 0.662 ± 0.0
3.309PheIle: 3.309 ± 0.0
5.625PheLys: 5.625 ± 0.0
3.64PheLeu: 3.64 ± 0.0
0.993PheMet: 0.993 ± 0.0
4.302PheAsn: 4.302 ± 0.0
1.985PhePro: 1.985 ± 0.0
0.662PheGln: 0.662 ± 0.0
1.324PheArg: 1.324 ± 0.0
5.625PheSer: 5.625 ± 0.0
1.985PheThr: 1.985 ± 0.0
3.309PheVal: 3.309 ± 0.0
0.0PheTrp: 0.0 ± 0.0
1.324PheTyr: 1.324 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
1.655GlyAla: 1.655 ± 0.0
0.993GlyCys: 0.993 ± 0.0
2.978GlyAsp: 2.978 ± 0.0
1.324GlyGlu: 1.324 ± 0.0
3.309GlyPhe: 3.309 ± 0.0
1.985GlyGly: 1.985 ± 0.0
0.662GlyHis: 0.662 ± 0.0
4.964GlyIle: 4.964 ± 0.0
4.302GlyLys: 4.302 ± 0.0
3.64GlyLeu: 3.64 ± 0.0
0.662GlyMet: 0.662 ± 0.0
1.985GlyAsn: 1.985 ± 0.0
0.993GlyPro: 0.993 ± 0.0
2.978GlyGln: 2.978 ± 0.0
1.655GlyArg: 1.655 ± 0.0
4.302GlySer: 4.302 ± 0.0
0.993GlyThr: 0.993 ± 0.0
3.64GlyVal: 3.64 ± 0.0
1.655GlyTrp: 1.655 ± 0.0
3.64GlyTyr: 3.64 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.993HisAsp: 0.993 ± 0.0
0.662HisGlu: 0.662 ± 0.0
1.324HisPhe: 1.324 ± 0.0
0.993HisGly: 0.993 ± 0.0
0.662HisHis: 0.662 ± 0.0
0.993HisIle: 0.993 ± 0.0
0.662HisLys: 0.662 ± 0.0
1.324HisLeu: 1.324 ± 0.0
0.331HisMet: 0.331 ± 0.0
0.662HisAsn: 0.662 ± 0.0
1.985HisPro: 1.985 ± 0.0
0.0HisGln: 0.0 ± 0.0
0.331HisArg: 0.331 ± 0.0
0.662HisSer: 0.662 ± 0.0
1.985HisThr: 1.985 ± 0.0
1.324HisVal: 1.324 ± 0.0
0.331HisTrp: 0.331 ± 0.0
1.324HisTyr: 1.324 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.633IleAla: 4.633 ± 0.0
1.324IleCys: 1.324 ± 0.0
4.302IleAsp: 4.302 ± 0.0
4.964IleGlu: 4.964 ± 0.0
2.978IlePhe: 2.978 ± 0.0
5.625IleGly: 5.625 ± 0.0
1.655IleHis: 1.655 ± 0.0
3.309IleIle: 3.309 ± 0.0
6.618IleLys: 6.618 ± 0.0
6.618IleLeu: 6.618 ± 0.0
0.331IleMet: 0.331 ± 0.0
5.625IleAsn: 5.625 ± 0.0
3.64IlePro: 3.64 ± 0.0
2.316IleGln: 2.316 ± 0.0
3.64IleArg: 3.64 ± 0.0
9.265IleSer: 9.265 ± 0.0
3.971IleThr: 3.971 ± 0.0
4.633IleVal: 4.633 ± 0.0
1.324IleTrp: 1.324 ± 0.0
2.316IleTyr: 2.316 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.309LysAla: 3.309 ± 0.0
0.331LysCys: 0.331 ± 0.0
4.964LysAsp: 4.964 ± 0.0
6.618LysGlu: 6.618 ± 0.0
3.64LysPhe: 3.64 ± 0.0
2.978LysGly: 2.978 ± 0.0
1.324LysHis: 1.324 ± 0.0
9.927LysIle: 9.927 ± 0.0
9.265LysLys: 9.265 ± 0.0
6.618LysLeu: 6.618 ± 0.0
2.978LysMet: 2.978 ± 0.0
2.978LysAsn: 2.978 ± 0.0
3.64LysPro: 3.64 ± 0.0
0.993LysGln: 0.993 ± 0.0
3.309LysArg: 3.309 ± 0.0
7.28LysSer: 7.28 ± 0.0
3.64LysThr: 3.64 ± 0.0
6.287LysVal: 6.287 ± 0.0
0.331LysTrp: 0.331 ± 0.0
1.655LysTyr: 1.655 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
5.625LeuAla: 5.625 ± 0.0
2.316LeuCys: 2.316 ± 0.0
6.618LeuAsp: 6.618 ± 0.0
5.625LeuGlu: 5.625 ± 0.0
3.971LeuPhe: 3.971 ± 0.0
2.316LeuGly: 2.316 ± 0.0
0.331LeuHis: 0.331 ± 0.0
6.618LeuIle: 6.618 ± 0.0
7.611LeuLys: 7.611 ± 0.0
3.971LeuLeu: 3.971 ± 0.0
0.993LeuMet: 0.993 ± 0.0
6.949LeuAsn: 6.949 ± 0.0
3.64LeuPro: 3.64 ± 0.0
3.64LeuGln: 3.64 ± 0.0
4.633LeuArg: 4.633 ± 0.0
8.604LeuSer: 8.604 ± 0.0
2.978LeuThr: 2.978 ± 0.0
5.956LeuVal: 5.956 ± 0.0
1.324LeuTrp: 1.324 ± 0.0
2.978LeuTyr: 2.978 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.662MetCys: 0.662 ± 0.0
2.316MetAsp: 2.316 ± 0.0
0.993MetGlu: 0.993 ± 0.0
1.324MetPhe: 1.324 ± 0.0
0.662MetGly: 0.662 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.331MetIle: 0.331 ± 0.0
1.985MetLys: 1.985 ± 0.0
1.324MetLeu: 1.324 ± 0.0
0.0MetMet: 0.0 ± 0.0
1.985MetAsn: 1.985 ± 0.0
0.662MetPro: 0.662 ± 0.0
0.0MetGln: 0.0 ± 0.0
1.985MetArg: 1.985 ± 0.0
0.993MetSer: 0.993 ± 0.0
1.324MetThr: 1.324 ± 0.0
0.993MetVal: 0.993 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.331MetTyr: 0.331 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.309AsnAla: 3.309 ± 0.0
0.662AsnCys: 0.662 ± 0.0
1.985AsnAsp: 1.985 ± 0.0
2.978AsnGlu: 2.978 ± 0.0
3.64AsnPhe: 3.64 ± 0.0
2.978AsnGly: 2.978 ± 0.0
0.662AsnHis: 0.662 ± 0.0
5.625AsnIle: 5.625 ± 0.0
5.625AsnLys: 5.625 ± 0.0
6.287AsnLeu: 6.287 ± 0.0
0.662AsnMet: 0.662 ± 0.0
3.64AsnAsn: 3.64 ± 0.0
1.985AsnPro: 1.985 ± 0.0
1.985AsnGln: 1.985 ± 0.0
2.316AsnArg: 2.316 ± 0.0
4.964AsnSer: 4.964 ± 0.0
2.647AsnThr: 2.647 ± 0.0
5.625AsnVal: 5.625 ± 0.0
0.993AsnTrp: 0.993 ± 0.0
3.971AsnTyr: 3.971 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
1.655ProAla: 1.655 ± 0.0
0.0ProCys: 0.0 ± 0.0
2.316ProAsp: 2.316 ± 0.0
2.316ProGlu: 2.316 ± 0.0
2.647ProPhe: 2.647 ± 0.0
1.324ProGly: 1.324 ± 0.0
0.662ProHis: 0.662 ± 0.0
1.985ProIle: 1.985 ± 0.0
3.971ProLys: 3.971 ± 0.0
4.302ProLeu: 4.302 ± 0.0
0.662ProMet: 0.662 ± 0.0
1.324ProAsn: 1.324 ± 0.0
2.316ProPro: 2.316 ± 0.0
2.978ProGln: 2.978 ± 0.0
1.655ProArg: 1.655 ± 0.0
2.316ProSer: 2.316 ± 0.0
2.647ProThr: 2.647 ± 0.0
3.64ProVal: 3.64 ± 0.0
1.655ProTrp: 1.655 ± 0.0
2.647ProTyr: 2.647 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
0.993GlnAla: 0.993 ± 0.0
0.662GlnCys: 0.662 ± 0.0
1.655GlnAsp: 1.655 ± 0.0
2.647GlnGlu: 2.647 ± 0.0
1.985GlnPhe: 1.985 ± 0.0
1.324GlnGly: 1.324 ± 0.0
0.662GlnHis: 0.662 ± 0.0
2.316GlnIle: 2.316 ± 0.0
2.316GlnLys: 2.316 ± 0.0
1.324GlnLeu: 1.324 ± 0.0
2.316GlnMet: 2.316 ± 0.0
1.324GlnAsn: 1.324 ± 0.0
1.985GlnPro: 1.985 ± 0.0
1.324GlnGln: 1.324 ± 0.0
1.985GlnArg: 1.985 ± 0.0
2.647GlnSer: 2.647 ± 0.0
0.662GlnThr: 0.662 ± 0.0
1.985GlnVal: 1.985 ± 0.0
0.993GlnTrp: 0.993 ± 0.0
0.993GlnTyr: 0.993 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
1.655ArgAla: 1.655 ± 0.0
1.985ArgCys: 1.985 ± 0.0
3.971ArgAsp: 3.971 ± 0.0
2.647ArgGlu: 2.647 ± 0.0
2.978ArgPhe: 2.978 ± 0.0
1.324ArgGly: 1.324 ± 0.0
0.331ArgHis: 0.331 ± 0.0
2.316ArgIle: 2.316 ± 0.0
1.655ArgLys: 1.655 ± 0.0
3.971ArgLeu: 3.971 ± 0.0
0.331ArgMet: 0.331 ± 0.0
2.647ArgAsn: 2.647 ± 0.0
1.324ArgPro: 1.324 ± 0.0
0.662ArgGln: 0.662 ± 0.0
2.647ArgArg: 2.647 ± 0.0
3.971ArgSer: 3.971 ± 0.0
2.316ArgThr: 2.316 ± 0.0
1.985ArgVal: 1.985 ± 0.0
0.662ArgTrp: 0.662 ± 0.0
2.316ArgTyr: 2.316 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
1.985SerAla: 1.985 ± 0.0
0.662SerCys: 0.662 ± 0.0
3.64SerAsp: 3.64 ± 0.0
4.302SerGlu: 4.302 ± 0.0
4.964SerPhe: 4.964 ± 0.0
5.625SerGly: 5.625 ± 0.0
0.331SerHis: 0.331 ± 0.0
7.942SerIle: 7.942 ± 0.0
3.309SerLys: 3.309 ± 0.0
10.589SerLeu: 10.589 ± 0.0
0.993SerMet: 0.993 ± 0.0
7.28SerAsn: 7.28 ± 0.0
3.64SerPro: 3.64 ± 0.0
2.316SerGln: 2.316 ± 0.0
1.324SerArg: 1.324 ± 0.0
7.942SerSer: 7.942 ± 0.0
5.295SerThr: 5.295 ± 0.0
5.956SerVal: 5.956 ± 0.0
2.978SerTrp: 2.978 ± 0.0
2.978SerTyr: 2.978 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
1.985ThrAla: 1.985 ± 0.0
0.331ThrCys: 0.331 ± 0.0
3.971ThrAsp: 3.971 ± 0.0
3.309ThrGlu: 3.309 ± 0.0
1.655ThrPhe: 1.655 ± 0.0
1.324ThrGly: 1.324 ± 0.0
1.985ThrHis: 1.985 ± 0.0
3.971ThrIle: 3.971 ± 0.0
1.655ThrLys: 1.655 ± 0.0
4.302ThrLeu: 4.302 ± 0.0
0.993ThrMet: 0.993 ± 0.0
5.295ThrAsn: 5.295 ± 0.0
1.985ThrPro: 1.985 ± 0.0
1.985ThrGln: 1.985 ± 0.0
0.662ThrArg: 0.662 ± 0.0
3.971ThrSer: 3.971 ± 0.0
2.316ThrThr: 2.316 ± 0.0
2.978ThrVal: 2.978 ± 0.0
0.993ThrTrp: 0.993 ± 0.0
2.316ThrTyr: 2.316 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
3.309ValAla: 3.309 ± 0.0
0.993ValCys: 0.993 ± 0.0
3.64ValAsp: 3.64 ± 0.0
2.978ValGlu: 2.978 ± 0.0
3.64ValPhe: 3.64 ± 0.0
3.64ValGly: 3.64 ± 0.0
1.655ValHis: 1.655 ± 0.0
3.971ValIle: 3.971 ± 0.0
6.949ValLys: 6.949 ± 0.0
6.618ValLeu: 6.618 ± 0.0
0.662ValMet: 0.662 ± 0.0
3.64ValAsn: 3.64 ± 0.0
3.64ValPro: 3.64 ± 0.0
2.647ValGln: 2.647 ± 0.0
2.647ValArg: 2.647 ± 0.0
3.309ValSer: 3.309 ± 0.0
1.324ValThr: 1.324 ± 0.0
2.647ValVal: 2.647 ± 0.0
0.993ValTrp: 0.993 ± 0.0
3.309ValTyr: 3.309 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.662TrpAla: 0.662 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.662TrpAsp: 0.662 ± 0.0
2.316TrpGlu: 2.316 ± 0.0
0.993TrpPhe: 0.993 ± 0.0
0.331TrpGly: 0.331 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.662TrpIle: 0.662 ± 0.0
0.993TrpLys: 0.993 ± 0.0
2.316TrpLeu: 2.316 ± 0.0
0.662TrpMet: 0.662 ± 0.0
0.662TrpAsn: 0.662 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.662TrpGln: 0.662 ± 0.0
1.655TrpArg: 1.655 ± 0.0
1.324TrpSer: 1.324 ± 0.0
0.993TrpThr: 0.993 ± 0.0
1.655TrpVal: 1.655 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.993TrpTyr: 0.993 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.647TyrAla: 2.647 ± 0.0
0.993TyrCys: 0.993 ± 0.0
0.993TyrAsp: 0.993 ± 0.0
2.978TyrGlu: 2.978 ± 0.0
0.662TyrPhe: 0.662 ± 0.0
2.316TyrGly: 2.316 ± 0.0
1.985TyrHis: 1.985 ± 0.0
5.295TyrIle: 5.295 ± 0.0
2.647TyrLys: 2.647 ± 0.0
3.971TyrLeu: 3.971 ± 0.0
1.324TyrMet: 1.324 ± 0.0
3.309TyrAsn: 3.309 ± 0.0
2.316TyrPro: 2.316 ± 0.0
1.324TyrGln: 1.324 ± 0.0
0.993TyrArg: 0.993 ± 0.0
2.316TyrSer: 2.316 ± 0.0
2.978TyrThr: 2.978 ± 0.0
1.655TyrVal: 1.655 ± 0.0
0.662TyrTrp: 0.662 ± 0.0
2.316TyrTyr: 2.316 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (3023 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski