Amino acid dipepetide frequency for Isaria javanica chrysovirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.371AlaAla: 5.371 ± 1.677
1.023AlaCys: 1.023 ± 0.326
4.092AlaAsp: 4.092 ± 0.19
5.882AlaGlu: 5.882 ± 0.854
2.558AlaPhe: 2.558 ± 0.869
7.161AlaGly: 7.161 ± 0.612
2.046AlaHis: 2.046 ± 0.608
4.859AlaIle: 4.859 ± 1.027
3.069AlaLys: 3.069 ± 0.435
7.928AlaLeu: 7.928 ± 0.44
2.558AlaMet: 2.558 ± 0.347
3.325AlaAsn: 3.325 ± 0.455
1.023AlaPro: 1.023 ± 0.047
0.767AlaGln: 0.767 ± 0.629
6.65AlaArg: 6.65 ± 0.465
5.115AlaSer: 5.115 ± 0.451
2.813AlaThr: 2.813 ± 0.654
4.092AlaVal: 4.092 ± 0.781
1.023AlaTrp: 1.023 ± 0.673
2.558AlaTyr: 2.558 ± 0.977
0.0AlaXaa: 0.0 ± 0.0
Cys
1.535CysAla: 1.535 ± 0.651
0.0CysCys: 0.0 ± 0.0
0.767CysAsp: 0.767 ± 0.248
1.79CysGlu: 1.79 ± 0.165
0.256CysPhe: 0.256 ± 0.227
1.535CysGly: 1.535 ± 0.574
0.767CysHis: 0.767 ± 0.629
0.512CysIle: 0.512 ± 0.42
0.767CysLys: 0.767 ± 0.63
0.512CysLeu: 0.512 ± 0.42
0.256CysMet: 0.256 ± 0.257
0.512CysAsn: 0.512 ± 0.454
0.512CysPro: 0.512 ± 0.278
0.767CysGln: 0.767 ± 0.193
1.279CysArg: 1.279 ± 0.482
2.302CysSer: 2.302 ± 0.505
0.256CysThr: 0.256 ± 0.257
1.279CysVal: 1.279 ± 0.556
0.512CysTrp: 0.512 ± 0.278
0.767CysTyr: 0.767 ± 0.63
0.0CysXaa: 0.0 ± 0.0
Asp
4.348AspAla: 4.348 ± 0.578
0.767AspCys: 0.767 ± 0.437
1.79AspAsp: 1.79 ± 0.449
3.325AspGlu: 3.325 ± 0.425
3.581AspPhe: 3.581 ± 0.785
3.836AspGly: 3.836 ± 0.914
0.512AspHis: 0.512 ± 0.42
4.092AspIle: 4.092 ± 1.195
2.302AspLys: 2.302 ± 1.483
4.604AspLeu: 4.604 ± 0.436
1.535AspMet: 1.535 ± 0.213
2.302AspAsn: 2.302 ± 0.467
2.046AspPro: 2.046 ± 0.743
3.325AspGln: 3.325 ± 0.707
5.627AspArg: 5.627 ± 0.744
3.325AspSer: 3.325 ± 0.909
1.79AspThr: 1.79 ± 0.384
4.859AspVal: 4.859 ± 1.058
1.023AspTrp: 1.023 ± 0.59
3.325AspTyr: 3.325 ± 1.033
0.0AspXaa: 0.0 ± 0.0
Glu
5.115GluAla: 5.115 ± 0.693
1.535GluCys: 1.535 ± 0.558
4.092GluAsp: 4.092 ± 0.44
5.882GluGlu: 5.882 ± 1.733
3.325GluPhe: 3.325 ± 0.776
4.859GluGly: 4.859 ± 0.438
1.023GluHis: 1.023 ± 0.047
2.813GluIle: 2.813 ± 0.827
5.371GluLys: 5.371 ± 0.429
6.65GluLeu: 6.65 ± 1.349
2.813GluMet: 2.813 ± 0.56
1.279GluAsn: 1.279 ± 0.628
2.813GluPro: 2.813 ± 0.283
2.558GluGln: 2.558 ± 0.547
5.627GluArg: 5.627 ± 0.919
2.302GluSer: 2.302 ± 0.306
1.79GluThr: 1.79 ± 0.165
6.394GluVal: 6.394 ± 1.058
1.535GluTrp: 1.535 ± 0.75
2.302GluTyr: 2.302 ± 0.546
0.0GluXaa: 0.0 ± 0.0
Phe
1.79PheAla: 1.79 ± 0.506
0.767PheCys: 0.767 ± 0.63
3.836PheAsp: 3.836 ± 1.0
2.558PheGlu: 2.558 ± 0.759
0.512PhePhe: 0.512 ± 0.278
3.581PheGly: 3.581 ± 1.268
0.256PheHis: 0.256 ± 0.21
2.046PheIle: 2.046 ± 0.581
1.79PheLys: 1.79 ± 0.329
2.558PheLeu: 2.558 ± 0.918
0.767PheMet: 0.767 ± 0.398
1.535PheAsn: 1.535 ± 0.699
0.512PhePro: 0.512 ± 0.237
0.767PheGln: 0.767 ± 0.193
1.79PheArg: 1.79 ± 0.506
3.325PheSer: 3.325 ± 1.141
2.046PheThr: 2.046 ± 0.399
2.046PheVal: 2.046 ± 0.512
0.256PheTrp: 0.256 ± 0.21
0.767PheTyr: 0.767 ± 0.398
0.0PheXaa: 0.0 ± 0.0
Gly
5.115GlyAla: 5.115 ± 0.956
1.279GlyCys: 1.279 ± 0.218
6.394GlyAsp: 6.394 ± 1.473
5.115GlyGlu: 5.115 ± 0.596
2.302GlyPhe: 2.302 ± 0.505
4.092GlyGly: 4.092 ± 1.141
1.535GlyHis: 1.535 ± 0.425
3.069GlyIle: 3.069 ± 0.862
4.859GlyLys: 4.859 ± 1.226
9.719GlyLeu: 9.719 ± 1.881
2.813GlyMet: 2.813 ± 0.615
2.558GlyAsn: 2.558 ± 0.347
2.813GlyPro: 2.813 ± 0.761
2.302GlyGln: 2.302 ± 0.424
6.138GlyArg: 6.138 ± 0.828
3.325GlySer: 3.325 ± 0.509
4.348GlyThr: 4.348 ± 1.399
5.115GlyVal: 5.115 ± 0.237
1.79GlyTrp: 1.79 ± 0.329
1.279GlyTyr: 1.279 ± 0.503
0.0GlyXaa: 0.0 ± 0.0
His
1.279HisAla: 1.279 ± 0.582
0.256HisCys: 0.256 ± 0.21
1.535HisAsp: 1.535 ± 0.308
0.767HisGlu: 0.767 ± 0.257
0.512HisPhe: 0.512 ± 0.42
1.535HisGly: 1.535 ± 0.579
0.0HisHis: 0.0 ± 0.0
1.535HisIle: 1.535 ± 0.671
1.279HisLys: 1.279 ± 0.442
3.069HisLeu: 3.069 ± 0.475
0.512HisMet: 0.512 ± 0.278
0.512HisAsn: 0.512 ± 0.42
0.256HisPro: 0.256 ± 0.21
0.767HisGln: 0.767 ± 0.494
1.279HisArg: 1.279 ± 0.684
2.302HisSer: 2.302 ± 0.796
1.535HisThr: 1.535 ± 0.651
1.79HisVal: 1.79 ± 0.506
1.023HisTrp: 1.023 ± 0.379
0.512HisTyr: 0.512 ± 0.514
0.0HisXaa: 0.0 ± 0.0
Ile
4.092IleAla: 4.092 ± 0.659
1.023IleCys: 1.023 ± 0.371
3.325IleAsp: 3.325 ± 0.532
3.836IleGlu: 3.836 ± 0.782
1.279IlePhe: 1.279 ± 0.503
3.836IleGly: 3.836 ± 1.032
0.767IleHis: 0.767 ± 0.494
1.535IleIle: 1.535 ± 0.284
1.279IleLys: 1.279 ± 0.431
3.581IleLeu: 3.581 ± 0.707
2.046IleMet: 2.046 ± 0.721
2.813IleAsn: 2.813 ± 0.283
3.069IlePro: 3.069 ± 0.142
1.279IleGln: 1.279 ± 0.265
2.046IleArg: 2.046 ± 0.837
4.092IleSer: 4.092 ± 0.94
2.302IleThr: 2.302 ± 0.608
3.325IleVal: 3.325 ± 0.421
0.512IleTrp: 0.512 ± 0.42
0.767IleTyr: 0.767 ± 0.193
0.0IleXaa: 0.0 ± 0.0
Lys
2.558LysAla: 2.558 ± 0.623
0.512LysCys: 0.512 ± 0.454
2.558LysAsp: 2.558 ± 0.552
4.348LysGlu: 4.348 ± 0.754
1.79LysPhe: 1.79 ± 0.362
4.604LysGly: 4.604 ± 1.172
1.79LysHis: 1.79 ± 0.662
3.581LysIle: 3.581 ± 0.45
1.79LysLys: 1.79 ± 0.266
4.092LysLeu: 4.092 ± 0.74
1.279LysMet: 1.279 ± 0.493
1.279LysAsn: 1.279 ± 0.378
2.558LysPro: 2.558 ± 0.759
2.046LysGln: 2.046 ± 0.243
3.581LysArg: 3.581 ± 0.186
4.348LysSer: 4.348 ± 0.649
3.069LysThr: 3.069 ± 0.142
5.371LysVal: 5.371 ± 0.566
1.279LysTrp: 1.279 ± 0.35
1.023LysTyr: 1.023 ± 0.549
0.0LysXaa: 0.0 ± 0.0
Leu
10.23LeuAla: 10.23 ± 0.767
1.79LeuCys: 1.79 ± 0.596
5.882LeuAsp: 5.882 ± 0.891
7.928LeuGlu: 7.928 ± 1.018
2.558LeuPhe: 2.558 ± 0.865
5.371LeuGly: 5.371 ± 1.431
1.79LeuHis: 1.79 ± 0.362
3.581LeuIle: 3.581 ± 0.924
3.836LeuLys: 3.836 ± 0.557
8.696LeuLeu: 8.696 ± 1.597
3.069LeuMet: 3.069 ± 0.631
4.348LeuAsn: 4.348 ± 0.87
4.859LeuPro: 4.859 ± 1.454
2.813LeuGln: 2.813 ± 1.075
5.371LeuArg: 5.371 ± 0.5
7.928LeuSer: 7.928 ± 1.174
4.604LeuThr: 4.604 ± 1.014
6.65LeuVal: 6.65 ± 0.833
1.279LeuTrp: 1.279 ± 0.662
2.302LeuTyr: 2.302 ± 0.43
0.0LeuXaa: 0.0 ± 0.0
Met
4.604MetAla: 4.604 ± 0.344
1.279MetCys: 1.279 ± 0.503
1.535MetAsp: 1.535 ± 0.212
1.279MetGlu: 1.279 ± 0.218
1.279MetPhe: 1.279 ± 0.469
1.279MetGly: 1.279 ± 0.482
0.512MetHis: 0.512 ± 0.239
0.767MetIle: 0.767 ± 0.437
1.79MetLys: 1.79 ± 0.489
2.813MetLeu: 2.813 ± 0.584
0.512MetMet: 0.512 ± 0.271
0.767MetAsn: 0.767 ± 0.367
3.325MetPro: 3.325 ± 0.93
0.512MetGln: 0.512 ± 0.514
2.046MetArg: 2.046 ± 0.608
3.581MetSer: 3.581 ± 0.186
0.767MetThr: 0.767 ± 0.448
3.325MetVal: 3.325 ± 0.674
0.512MetTrp: 0.512 ± 0.271
1.023MetTyr: 1.023 ± 0.555
0.0MetXaa: 0.0 ± 0.0
Asn
1.79AsnAla: 1.79 ± 0.471
0.767AsnCys: 0.767 ± 0.257
0.767AsnAsp: 0.767 ± 0.494
2.813AsnGlu: 2.813 ± 0.821
1.023AsnPhe: 1.023 ± 0.291
3.069AsnGly: 3.069 ± 0.617
0.512AsnHis: 0.512 ± 0.454
1.279AsnIle: 1.279 ± 0.482
2.046AsnLys: 2.046 ± 0.837
4.092AsnLeu: 4.092 ± 0.759
2.046AsnMet: 2.046 ± 0.845
1.79AsnAsn: 1.79 ± 0.506
0.767AsnPro: 0.767 ± 0.494
0.512AsnGln: 0.512 ± 0.42
2.558AsnArg: 2.558 ± 0.995
2.813AsnSer: 2.813 ± 0.247
2.302AsnThr: 2.302 ± 1.107
2.302AsnVal: 2.302 ± 1.016
0.512AsnTrp: 0.512 ± 0.278
0.512AsnTyr: 0.512 ± 0.237
0.0AsnXaa: 0.0 ± 0.0
Pro
1.535ProAla: 1.535 ± 0.425
0.256ProCys: 0.256 ± 0.21
2.813ProAsp: 2.813 ± 1.2
2.813ProGlu: 2.813 ± 0.855
0.512ProPhe: 0.512 ± 0.279
3.581ProGly: 3.581 ± 0.767
1.279ProHis: 1.279 ± 0.422
1.79ProIle: 1.79 ± 0.561
3.069ProLys: 3.069 ± 0.652
2.046ProLeu: 2.046 ± 0.401
1.279ProMet: 1.279 ± 0.265
1.023ProAsn: 1.023 ± 0.717
2.302ProPro: 2.302 ± 0.424
1.279ProGln: 1.279 ± 0.176
5.115ProArg: 5.115 ± 1.504
4.092ProSer: 4.092 ± 1.527
2.813ProThr: 2.813 ± 0.582
2.046ProVal: 2.046 ± 0.804
0.256ProTrp: 0.256 ± 0.21
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
3.069GlnAla: 3.069 ± 0.739
0.767GlnCys: 0.767 ± 0.257
1.535GlnAsp: 1.535 ± 0.713
2.046GlnGlu: 2.046 ± 0.773
1.279GlnPhe: 1.279 ± 0.378
2.558GlnGly: 2.558 ± 0.78
0.512GlnHis: 0.512 ± 0.278
1.535GlnIle: 1.535 ± 0.734
1.279GlnLys: 1.279 ± 0.218
3.581GlnLeu: 3.581 ± 0.906
1.279GlnMet: 1.279 ± 0.265
1.023GlnAsn: 1.023 ± 0.475
0.767GlnPro: 0.767 ± 0.193
1.023GlnGln: 1.023 ± 0.737
0.767GlnArg: 0.767 ± 0.437
2.813GlnSer: 2.813 ± 1.234
1.023GlnThr: 1.023 ± 0.291
2.302GlnVal: 2.302 ± 0.517
0.256GlnTrp: 0.256 ± 0.21
0.767GlnTyr: 0.767 ± 0.398
0.0GlnXaa: 0.0 ± 0.0
Arg
4.859ArgAla: 4.859 ± 0.776
1.279ArgCys: 1.279 ± 0.442
3.836ArgAsp: 3.836 ± 1.214
6.65ArgGlu: 6.65 ± 1.619
1.79ArgPhe: 1.79 ± 0.554
5.882ArgGly: 5.882 ± 0.79
2.558ArgHis: 2.558 ± 0.628
2.558ArgIle: 2.558 ± 1.262
3.325ArgLys: 3.325 ± 0.896
8.184ArgLeu: 8.184 ± 1.487
1.79ArgMet: 1.79 ± 0.929
2.558ArgAsn: 2.558 ± 0.623
2.558ArgPro: 2.558 ± 0.619
3.069ArgGln: 3.069 ± 0.794
6.65ArgArg: 6.65 ± 1.287
4.859ArgSer: 4.859 ± 0.602
3.069ArgThr: 3.069 ± 0.811
4.604ArgVal: 4.604 ± 0.617
1.279ArgTrp: 1.279 ± 0.55
1.279ArgTyr: 1.279 ± 0.503
0.0ArgXaa: 0.0 ± 0.0
Ser
5.115SerAla: 5.115 ± 0.806
0.512SerCys: 0.512 ± 0.268
4.859SerAsp: 4.859 ± 1.181
4.348SerGlu: 4.348 ± 0.393
3.069SerPhe: 3.069 ± 0.764
5.115SerGly: 5.115 ± 1.096
2.558SerHis: 2.558 ± 0.435
3.325SerIle: 3.325 ± 0.349
4.859SerLys: 4.859 ± 0.933
7.417SerLeu: 7.417 ± 0.211
2.302SerMet: 2.302 ± 0.791
2.046SerAsn: 2.046 ± 0.386
3.069SerPro: 3.069 ± 0.905
2.813SerGln: 2.813 ± 0.785
5.627SerArg: 5.627 ± 1.006
8.951SerSer: 8.951 ± 2.351
3.325SerThr: 3.325 ± 0.455
5.627SerVal: 5.627 ± 1.28
1.023SerTrp: 1.023 ± 0.047
3.581SerTyr: 3.581 ± 1.003
0.0SerXaa: 0.0 ± 0.0
Thr
2.046ThrAla: 2.046 ± 0.862
0.256ThrCys: 0.256 ± 0.21
0.767ThrAsp: 0.767 ± 0.257
3.325ThrGlu: 3.325 ± 0.964
2.302ThrPhe: 2.302 ± 0.856
3.325ThrGly: 3.325 ± 0.513
0.767ThrHis: 0.767 ± 0.422
3.325ThrIle: 3.325 ± 0.349
3.325ThrLys: 3.325 ± 1.151
4.604ThrLeu: 4.604 ± 0.881
2.558ThrMet: 2.558 ± 0.909
0.767ThrAsn: 0.767 ± 0.462
2.046ThrPro: 2.046 ± 0.456
1.279ThrGln: 1.279 ± 0.422
2.302ThrArg: 2.302 ± 0.623
4.092ThrSer: 4.092 ± 1.322
3.069ThrThr: 3.069 ± 0.762
4.092ThrVal: 4.092 ± 0.58
0.512ThrTrp: 0.512 ± 0.42
2.046ThrTyr: 2.046 ± 0.708
0.0ThrXaa: 0.0 ± 0.0
Val
6.138ValAla: 6.138 ± 0.961
2.046ValCys: 2.046 ± 0.96
5.371ValAsp: 5.371 ± 1.429
2.046ValGlu: 2.046 ± 0.793
2.302ValPhe: 2.302 ± 1.014
6.394ValGly: 6.394 ± 0.784
1.79ValHis: 1.79 ± 0.719
2.558ValIle: 2.558 ± 0.57
3.581ValLys: 3.581 ± 1.217
7.161ValLeu: 7.161 ± 0.78
3.069ValMet: 3.069 ± 0.588
2.046ValAsn: 2.046 ± 0.512
2.813ValPro: 2.813 ± 0.56
1.279ValGln: 1.279 ± 0.266
5.371ValArg: 5.371 ± 0.621
6.394ValSer: 6.394 ± 0.632
3.581ValThr: 3.581 ± 0.544
4.604ValVal: 4.604 ± 0.198
1.023ValTrp: 1.023 ± 0.047
2.558ValTyr: 2.558 ± 0.977
0.0ValXaa: 0.0 ± 0.0
Trp
1.023TrpAla: 1.023 ± 0.589
0.256TrpCys: 0.256 ± 0.21
0.0TrpAsp: 0.0 ± 0.0
1.535TrpGlu: 1.535 ± 0.308
0.256TrpPhe: 0.256 ± 0.21
1.279TrpGly: 1.279 ± 0.678
0.256TrpHis: 0.256 ± 0.227
1.279TrpIle: 1.279 ± 0.566
1.535TrpLys: 1.535 ± 0.574
1.79TrpLeu: 1.79 ± 0.561
0.256TrpMet: 0.256 ± 0.21
0.767TrpAsn: 0.767 ± 0.193
0.0TrpPro: 0.0 ± 0.0
0.256TrpGln: 0.256 ± 0.21
1.023TrpArg: 1.023 ± 0.324
1.535TrpSer: 1.535 ± 0.213
0.512TrpThr: 0.512 ± 0.42
1.023TrpVal: 1.023 ± 0.371
0.0TrpTrp: 0.0 ± 0.0
1.023TrpTyr: 1.023 ± 0.386
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.302TyrAla: 2.302 ± 0.623
0.512TyrCys: 0.512 ± 0.278
2.558TyrAsp: 2.558 ± 0.352
1.79TyrGlu: 1.79 ± 0.854
1.023TyrPhe: 1.023 ± 0.475
3.069TyrGly: 3.069 ± 0.407
1.023TyrHis: 1.023 ± 0.423
0.767TyrIle: 0.767 ± 0.193
2.302TyrLys: 2.302 ± 0.424
1.79TyrLeu: 1.79 ± 0.774
0.512TyrMet: 0.512 ± 0.278
1.023TyrAsn: 1.023 ± 0.381
1.79TyrPro: 1.79 ± 0.225
0.767TyrGln: 0.767 ± 0.193
1.79TyrArg: 1.79 ± 0.492
2.046TyrSer: 2.046 ± 0.433
1.79TyrThr: 1.79 ± 0.757
1.535TyrVal: 1.535 ± 0.948
0.0TyrTrp: 0.0 ± 0.0
1.023TyrTyr: 1.023 ± 0.59
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3911 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski