Amino acid dipepetide frequency for Hubei picorna-like virus 10

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.108AlaAla: 4.108 ± 0.0
0.0AlaCys: 0.0 ± 0.0
2.614AlaAsp: 2.614 ± 0.0
2.614AlaGlu: 2.614 ± 0.0
1.12AlaPhe: 1.12 ± 0.0
5.601AlaGly: 5.601 ± 0.0
0.747AlaHis: 0.747 ± 0.0
5.228AlaIle: 5.228 ± 0.0
3.361AlaLys: 3.361 ± 0.0
4.854AlaLeu: 4.854 ± 0.0
1.867AlaMet: 1.867 ± 0.0
1.494AlaAsn: 1.494 ± 0.0
3.361AlaPro: 3.361 ± 0.0
0.373AlaGln: 0.373 ± 0.0
2.24AlaArg: 2.24 ± 0.0
3.734AlaSer: 3.734 ± 0.0
3.734AlaThr: 3.734 ± 0.0
5.601AlaVal: 5.601 ± 0.0
0.373AlaTrp: 0.373 ± 0.0
2.614AlaTyr: 2.614 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.747CysAla: 0.747 ± 0.0
0.373CysCys: 0.373 ± 0.0
1.867CysAsp: 1.867 ± 0.0
1.867CysGlu: 1.867 ± 0.0
0.747CysPhe: 0.747 ± 0.0
2.24CysGly: 2.24 ± 0.0
0.373CysHis: 0.373 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.494CysLys: 1.494 ± 0.0
1.494CysLeu: 1.494 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.747CysPro: 0.747 ± 0.0
0.747CysGln: 0.747 ± 0.0
0.747CysArg: 0.747 ± 0.0
0.373CysSer: 0.373 ± 0.0
0.747CysThr: 0.747 ± 0.0
0.373CysVal: 0.373 ± 0.0
0.373CysTrp: 0.373 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.481AspAla: 4.481 ± 0.0
1.494AspCys: 1.494 ± 0.0
4.108AspAsp: 4.108 ± 0.0
3.361AspGlu: 3.361 ± 0.0
2.614AspPhe: 2.614 ± 0.0
3.361AspGly: 3.361 ± 0.0
1.12AspHis: 1.12 ± 0.0
5.228AspIle: 5.228 ± 0.0
2.24AspLys: 2.24 ± 0.0
3.361AspLeu: 3.361 ± 0.0
1.12AspMet: 1.12 ± 0.0
2.987AspAsn: 2.987 ± 0.0
1.494AspPro: 1.494 ± 0.0
3.361AspGln: 3.361 ± 0.0
1.867AspArg: 1.867 ± 0.0
1.12AspSer: 1.12 ± 0.0
3.734AspThr: 3.734 ± 0.0
2.614AspVal: 2.614 ± 0.0
1.12AspTrp: 1.12 ± 0.0
4.108AspTyr: 4.108 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
2.987GluAla: 2.987 ± 0.0
0.747GluCys: 0.747 ± 0.0
2.24GluAsp: 2.24 ± 0.0
1.867GluGlu: 1.867 ± 0.0
5.228GluPhe: 5.228 ± 0.0
3.734GluGly: 3.734 ± 0.0
1.12GluHis: 1.12 ± 0.0
3.361GluIle: 3.361 ± 0.0
4.108GluLys: 4.108 ± 0.0
6.348GluLeu: 6.348 ± 0.0
1.12GluMet: 1.12 ± 0.0
2.614GluAsn: 2.614 ± 0.0
2.987GluPro: 2.987 ± 0.0
1.867GluGln: 1.867 ± 0.0
2.987GluArg: 2.987 ± 0.0
5.228GluSer: 5.228 ± 0.0
4.481GluThr: 4.481 ± 0.0
6.721GluVal: 6.721 ± 0.0
0.373GluTrp: 0.373 ± 0.0
2.24GluTyr: 2.24 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
3.361PheAla: 3.361 ± 0.0
1.12PheCys: 1.12 ± 0.0
2.987PheAsp: 2.987 ± 0.0
2.614PheGlu: 2.614 ± 0.0
2.24PhePhe: 2.24 ± 0.0
5.228PheGly: 5.228 ± 0.0
1.867PheHis: 1.867 ± 0.0
1.494PheIle: 1.494 ± 0.0
3.361PheLys: 3.361 ± 0.0
2.987PheLeu: 2.987 ± 0.0
1.494PheMet: 1.494 ± 0.0
1.867PheAsn: 1.867 ± 0.0
2.614PhePro: 2.614 ± 0.0
1.12PheGln: 1.12 ± 0.0
2.614PheArg: 2.614 ± 0.0
7.468PheSer: 7.468 ± 0.0
4.481PheThr: 4.481 ± 0.0
5.228PheVal: 5.228 ± 0.0
0.747PheTrp: 0.747 ± 0.0
0.747PheTyr: 0.747 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
2.614GlyAla: 2.614 ± 0.0
0.373GlyCys: 0.373 ± 0.0
4.108GlyAsp: 4.108 ± 0.0
2.987GlyGlu: 2.987 ± 0.0
2.24GlyPhe: 2.24 ± 0.0
3.734GlyGly: 3.734 ± 0.0
1.12GlyHis: 1.12 ± 0.0
5.975GlyIle: 5.975 ± 0.0
3.361GlyLys: 3.361 ± 0.0
5.601GlyLeu: 5.601 ± 0.0
1.867GlyMet: 1.867 ± 0.0
3.361GlyAsn: 3.361 ± 0.0
2.987GlyPro: 2.987 ± 0.0
1.494GlyGln: 1.494 ± 0.0
1.867GlyArg: 1.867 ± 0.0
5.228GlySer: 5.228 ± 0.0
5.601GlyThr: 5.601 ± 0.0
5.228GlyVal: 5.228 ± 0.0
0.747GlyTrp: 0.747 ± 0.0
1.867GlyTyr: 1.867 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.12HisAla: 1.12 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.747HisAsp: 0.747 ± 0.0
2.614HisGlu: 2.614 ± 0.0
1.12HisPhe: 1.12 ± 0.0
2.24HisGly: 2.24 ± 0.0
0.747HisHis: 0.747 ± 0.0
0.747HisIle: 0.747 ± 0.0
0.0HisLys: 0.0 ± 0.0
1.494HisLeu: 1.494 ± 0.0
0.747HisMet: 0.747 ± 0.0
0.747HisAsn: 0.747 ± 0.0
1.494HisPro: 1.494 ± 0.0
0.373HisGln: 0.373 ± 0.0
1.494HisArg: 1.494 ± 0.0
1.12HisSer: 1.12 ± 0.0
1.494HisThr: 1.494 ± 0.0
2.24HisVal: 2.24 ± 0.0
0.373HisTrp: 0.373 ± 0.0
1.494HisTyr: 1.494 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.734IleAla: 3.734 ± 0.0
1.12IleCys: 1.12 ± 0.0
3.361IleAsp: 3.361 ± 0.0
4.108IleGlu: 4.108 ± 0.0
1.867IlePhe: 1.867 ± 0.0
4.854IleGly: 4.854 ± 0.0
2.24IleHis: 2.24 ± 0.0
4.854IleIle: 4.854 ± 0.0
4.854IleLys: 4.854 ± 0.0
5.975IleLeu: 5.975 ± 0.0
1.12IleMet: 1.12 ± 0.0
2.614IleAsn: 2.614 ± 0.0
6.348IlePro: 6.348 ± 0.0
2.987IleGln: 2.987 ± 0.0
3.734IleArg: 3.734 ± 0.0
5.228IleSer: 5.228 ± 0.0
3.361IleThr: 3.361 ± 0.0
4.854IleVal: 4.854 ± 0.0
0.373IleTrp: 0.373 ± 0.0
3.361IleTyr: 3.361 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
1.867LysAla: 1.867 ± 0.0
0.0LysCys: 0.0 ± 0.0
2.24LysAsp: 2.24 ± 0.0
5.975LysGlu: 5.975 ± 0.0
3.734LysPhe: 3.734 ± 0.0
3.361LysGly: 3.361 ± 0.0
1.494LysHis: 1.494 ± 0.0
5.601LysIle: 5.601 ± 0.0
4.108LysLys: 4.108 ± 0.0
4.481LysLeu: 4.481 ± 0.0
1.494LysMet: 1.494 ± 0.0
2.987LysAsn: 2.987 ± 0.0
1.494LysPro: 1.494 ± 0.0
2.24LysGln: 2.24 ± 0.0
2.24LysArg: 2.24 ± 0.0
4.108LysSer: 4.108 ± 0.0
1.867LysThr: 1.867 ± 0.0
3.734LysVal: 3.734 ± 0.0
1.494LysTrp: 1.494 ± 0.0
0.747LysTyr: 0.747 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
7.095LeuAla: 7.095 ± 0.0
2.24LeuCys: 2.24 ± 0.0
4.108LeuAsp: 4.108 ± 0.0
2.24LeuGlu: 2.24 ± 0.0
1.494LeuPhe: 1.494 ± 0.0
4.481LeuGly: 4.481 ± 0.0
0.373LeuHis: 0.373 ± 0.0
5.228LeuIle: 5.228 ± 0.0
4.481LeuLys: 4.481 ± 0.0
8.962LeuLeu: 8.962 ± 0.0
1.494LeuMet: 1.494 ± 0.0
4.108LeuAsn: 4.108 ± 0.0
3.361LeuPro: 3.361 ± 0.0
3.361LeuGln: 3.361 ± 0.0
4.481LeuArg: 4.481 ± 0.0
4.854LeuSer: 4.854 ± 0.0
7.095LeuThr: 7.095 ± 0.0
5.975LeuVal: 5.975 ± 0.0
0.747LeuTrp: 0.747 ± 0.0
2.24LeuTyr: 2.24 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
1.867MetAla: 1.867 ± 0.0
0.747MetCys: 0.747 ± 0.0
1.867MetAsp: 1.867 ± 0.0
1.867MetGlu: 1.867 ± 0.0
1.12MetPhe: 1.12 ± 0.0
1.12MetGly: 1.12 ± 0.0
0.747MetHis: 0.747 ± 0.0
1.494MetIle: 1.494 ± 0.0
1.494MetLys: 1.494 ± 0.0
2.24MetLeu: 2.24 ± 0.0
0.373MetMet: 0.373 ± 0.0
1.867MetAsn: 1.867 ± 0.0
2.24MetPro: 2.24 ± 0.0
0.373MetGln: 0.373 ± 0.0
0.373MetArg: 0.373 ± 0.0
2.24MetSer: 2.24 ± 0.0
1.12MetThr: 1.12 ± 0.0
0.747MetVal: 0.747 ± 0.0
0.747MetTrp: 0.747 ± 0.0
1.12MetTyr: 1.12 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.24AsnAla: 2.24 ± 0.0
0.747AsnCys: 0.747 ± 0.0
1.867AsnAsp: 1.867 ± 0.0
4.108AsnGlu: 4.108 ± 0.0
4.108AsnPhe: 4.108 ± 0.0
0.747AsnGly: 0.747 ± 0.0
0.747AsnHis: 0.747 ± 0.0
4.481AsnIle: 4.481 ± 0.0
2.614AsnLys: 2.614 ± 0.0
3.734AsnLeu: 3.734 ± 0.0
1.494AsnMet: 1.494 ± 0.0
4.854AsnAsn: 4.854 ± 0.0
1.867AsnPro: 1.867 ± 0.0
1.867AsnGln: 1.867 ± 0.0
1.12AsnArg: 1.12 ± 0.0
2.614AsnSer: 2.614 ± 0.0
4.854AsnThr: 4.854 ± 0.0
5.975AsnVal: 5.975 ± 0.0
0.373AsnTrp: 0.373 ± 0.0
2.24AsnTyr: 2.24 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
1.867ProAla: 1.867 ± 0.0
1.12ProCys: 1.12 ± 0.0
3.734ProAsp: 3.734 ± 0.0
2.614ProGlu: 2.614 ± 0.0
3.734ProPhe: 3.734 ± 0.0
3.361ProGly: 3.361 ± 0.0
0.0ProHis: 0.0 ± 0.0
4.854ProIle: 4.854 ± 0.0
2.24ProLys: 2.24 ± 0.0
3.734ProLeu: 3.734 ± 0.0
2.24ProMet: 2.24 ± 0.0
2.987ProAsn: 2.987 ± 0.0
3.361ProPro: 3.361 ± 0.0
2.614ProGln: 2.614 ± 0.0
2.987ProArg: 2.987 ± 0.0
2.614ProSer: 2.614 ± 0.0
3.734ProThr: 3.734 ± 0.0
4.108ProVal: 4.108 ± 0.0
0.0ProTrp: 0.0 ± 0.0
0.747ProTyr: 0.747 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.867GlnAla: 1.867 ± 0.0
0.747GlnCys: 0.747 ± 0.0
2.614GlnAsp: 2.614 ± 0.0
3.361GlnGlu: 3.361 ± 0.0
1.867GlnPhe: 1.867 ± 0.0
0.747GlnGly: 0.747 ± 0.0
0.747GlnHis: 0.747 ± 0.0
1.494GlnIle: 1.494 ± 0.0
1.494GlnLys: 1.494 ± 0.0
2.614GlnLeu: 2.614 ± 0.0
0.747GlnMet: 0.747 ± 0.0
2.614GlnAsn: 2.614 ± 0.0
1.12GlnPro: 1.12 ± 0.0
1.494GlnGln: 1.494 ± 0.0
0.0GlnArg: 0.0 ± 0.0
2.987GlnSer: 2.987 ± 0.0
3.361GlnThr: 3.361 ± 0.0
1.12GlnVal: 1.12 ± 0.0
0.373GlnTrp: 0.373 ± 0.0
0.747GlnTyr: 0.747 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.24ArgAla: 2.24 ± 0.0
0.373ArgCys: 0.373 ± 0.0
2.24ArgAsp: 2.24 ± 0.0
2.24ArgGlu: 2.24 ± 0.0
2.987ArgPhe: 2.987 ± 0.0
0.747ArgGly: 0.747 ± 0.0
0.747ArgHis: 0.747 ± 0.0
4.481ArgIle: 4.481 ± 0.0
1.494ArgLys: 1.494 ± 0.0
2.614ArgLeu: 2.614 ± 0.0
1.867ArgMet: 1.867 ± 0.0
4.108ArgAsn: 4.108 ± 0.0
2.24ArgPro: 2.24 ± 0.0
0.747ArgGln: 0.747 ± 0.0
1.867ArgArg: 1.867 ± 0.0
2.614ArgSer: 2.614 ± 0.0
2.24ArgThr: 2.24 ± 0.0
3.734ArgVal: 3.734 ± 0.0
0.0ArgTrp: 0.0 ± 0.0
2.24ArgTyr: 2.24 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
2.24SerAla: 2.24 ± 0.0
1.494SerCys: 1.494 ± 0.0
2.614SerAsp: 2.614 ± 0.0
5.975SerGlu: 5.975 ± 0.0
5.228SerPhe: 5.228 ± 0.0
7.468SerGly: 7.468 ± 0.0
2.24SerHis: 2.24 ± 0.0
4.481SerIle: 4.481 ± 0.0
2.987SerLys: 2.987 ± 0.0
2.987SerLeu: 2.987 ± 0.0
1.867SerMet: 1.867 ± 0.0
4.854SerAsn: 4.854 ± 0.0
3.361SerPro: 3.361 ± 0.0
0.747SerGln: 0.747 ± 0.0
3.734SerArg: 3.734 ± 0.0
5.228SerSer: 5.228 ± 0.0
4.108SerThr: 4.108 ± 0.0
5.601SerVal: 5.601 ± 0.0
1.494SerTrp: 1.494 ± 0.0
1.494SerTyr: 1.494 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
2.987ThrAla: 2.987 ± 0.0
0.747ThrCys: 0.747 ± 0.0
2.987ThrAsp: 2.987 ± 0.0
5.975ThrGlu: 5.975 ± 0.0
4.854ThrPhe: 4.854 ± 0.0
2.614ThrGly: 2.614 ± 0.0
1.12ThrHis: 1.12 ± 0.0
7.095ThrIle: 7.095 ± 0.0
4.854ThrLys: 4.854 ± 0.0
5.228ThrLeu: 5.228 ± 0.0
1.867ThrMet: 1.867 ± 0.0
2.987ThrAsn: 2.987 ± 0.0
4.481ThrPro: 4.481 ± 0.0
2.614ThrGln: 2.614 ± 0.0
2.24ThrArg: 2.24 ± 0.0
4.108ThrSer: 4.108 ± 0.0
5.228ThrThr: 5.228 ± 0.0
3.734ThrVal: 3.734 ± 0.0
0.373ThrTrp: 0.373 ± 0.0
2.987ThrTyr: 2.987 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
6.348ValAla: 6.348 ± 0.0
0.747ValCys: 0.747 ± 0.0
5.601ValAsp: 5.601 ± 0.0
3.361ValGlu: 3.361 ± 0.0
7.095ValPhe: 7.095 ± 0.0
2.987ValGly: 2.987 ± 0.0
2.24ValHis: 2.24 ± 0.0
3.361ValIle: 3.361 ± 0.0
4.854ValLys: 4.854 ± 0.0
5.975ValLeu: 5.975 ± 0.0
1.867ValMet: 1.867 ± 0.0
3.734ValAsn: 3.734 ± 0.0
4.108ValPro: 4.108 ± 0.0
1.867ValGln: 1.867 ± 0.0
2.24ValArg: 2.24 ± 0.0
5.975ValSer: 5.975 ± 0.0
5.975ValThr: 5.975 ± 0.0
4.481ValVal: 4.481 ± 0.0
0.373ValTrp: 0.373 ± 0.0
2.24ValTyr: 2.24 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.373TrpAla: 0.373 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.747TrpAsp: 0.747 ± 0.0
0.747TrpGlu: 0.747 ± 0.0
1.12TrpPhe: 1.12 ± 0.0
0.373TrpGly: 0.373 ± 0.0
0.373TrpHis: 0.373 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.373TrpLys: 0.373 ± 0.0
1.494TrpLeu: 1.494 ± 0.0
0.373TrpMet: 0.373 ± 0.0
0.373TrpAsn: 0.373 ± 0.0
1.12TrpPro: 1.12 ± 0.0
0.373TrpGln: 0.373 ± 0.0
0.747TrpArg: 0.747 ± 0.0
1.12TrpSer: 1.12 ± 0.0
0.373TrpThr: 0.373 ± 0.0
1.12TrpVal: 1.12 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.494TyrAla: 1.494 ± 0.0
1.12TyrCys: 1.12 ± 0.0
2.24TyrAsp: 2.24 ± 0.0
1.867TyrGlu: 1.867 ± 0.0
1.12TyrPhe: 1.12 ± 0.0
3.361TyrGly: 3.361 ± 0.0
2.24TyrHis: 2.24 ± 0.0
1.494TyrIle: 1.494 ± 0.0
1.494TyrLys: 1.494 ± 0.0
2.614TyrLeu: 2.614 ± 0.0
0.373TyrMet: 0.373 ± 0.0
1.494TyrAsn: 1.494 ± 0.0
1.867TyrPro: 1.867 ± 0.0
1.494TyrGln: 1.494 ± 0.0
2.24TyrArg: 2.24 ± 0.0
2.24TyrSer: 2.24 ± 0.0
1.494TyrThr: 1.494 ± 0.0
2.24TyrVal: 2.24 ± 0.0
0.747TyrTrp: 0.747 ± 0.0
2.614TyrTyr: 2.614 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2679 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski