Amino acid dipepetide frequency for Robiginitalea biformata (strain ATCC BAA-864 / HTCC2501 / KCTC 12146)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.563AlaAla: 7.563 ± 0.104	0.788AlaCys: 0.788 ± 0.024	4.993AlaAsp: 4.993 ± 0.08	5.475AlaGlu: 5.475 ± 0.078	3.89AlaPhe: 3.89 ± 0.062	7.256AlaGly: 7.256 ± 0.105	1.486AlaHis: 1.486 ± 0.043	4.912AlaIle: 4.912 ± 0.071	2.888AlaLys: 2.888 ± 0.064	8.394AlaLeu: 8.394 ± 0.104	1.841AlaMet: 1.841 ± 0.042	2.963AlaAsn: 2.963 ± 0.064	3.058AlaPro: 3.058 ± 0.072	2.725AlaGln: 2.725 ± 0.053	4.961AlaArg: 4.961 ± 0.088	4.993AlaSer: 4.993 ± 0.084	4.047AlaThr: 4.047 ± 0.081	5.432AlaVal: 5.432 ± 0.083	1.015AlaTrp: 1.015 ± 0.034	3.109AlaTyr: 3.109 ± 0.06	0.0AlaXaa: 0.0 ± 0.0
Cys	0.528CysAla: 0.528 ± 0.026	0.103CysCys: 0.103 ± 0.011	0.421CysAsp: 0.421 ± 0.025	0.444CysGlu: 0.444 ± 0.02	0.335CysPhe: 0.335 ± 0.018	0.727CysGly: 0.727 ± 0.029	0.199CysHis: 0.199 ± 0.015	0.468CysIle: 0.468 ± 0.019	0.303CysLys: 0.303 ± 0.017	0.772CysLeu: 0.772 ± 0.028	0.179CysMet: 0.179 ± 0.012	0.313CysAsn: 0.313 ± 0.019	0.398CysPro: 0.398 ± 0.024	0.239CysGln: 0.239 ± 0.014	0.422CysArg: 0.422 ± 0.021	0.495CysSer: 0.495 ± 0.022	0.448CysThr: 0.448 ± 0.027	0.38CysVal: 0.38 ± 0.022	0.078CysTrp: 0.078 ± 0.008	0.281CysTyr: 0.281 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	4.996AspAla: 4.996 ± 0.085	0.454AspCys: 0.454 ± 0.029	2.868AspAsp: 2.868 ± 0.084	3.236AspGlu: 3.236 ± 0.06	3.204AspPhe: 3.204 ± 0.055	5.025AspGly: 5.025 ± 0.117	1.152AspHis: 1.152 ± 0.033	3.673AspIle: 3.673 ± 0.065	2.475AspLys: 2.475 ± 0.059	5.852AspLeu: 5.852 ± 0.092	1.308AspMet: 1.308 ± 0.032	2.39AspAsn: 2.39 ± 0.089	3.271AspPro: 3.271 ± 0.077	2.004AspGln: 2.004 ± 0.06	3.557AspArg: 3.557 ± 0.064	3.605AspSer: 3.605 ± 0.063	3.182AspThr: 3.182 ± 0.055	3.326AspVal: 3.326 ± 0.074	0.855AspTrp: 0.855 ± 0.031	2.528AspTyr: 2.528 ± 0.056	0.0AspXaa: 0.0 ± 0.0
Glu	6.43GluAla: 6.43 ± 0.099	0.311GluCys: 0.311 ± 0.02	3.811GluAsp: 3.811 ± 0.065	5.097GluGlu: 5.097 ± 0.09	2.883GluPhe: 2.883 ± 0.055	4.756GluGly: 4.756 ± 0.065	1.273GluHis: 1.273 ± 0.034	4.667GluIle: 4.667 ± 0.083	4.244GluLys: 4.244 ± 0.086	6.587GluLeu: 6.587 ± 0.096	1.651GluMet: 1.651 ± 0.04	3.286GluAsn: 3.286 ± 0.055	2.506GluPro: 2.506 ± 0.05	2.504GluGln: 2.504 ± 0.058	3.609GluArg: 3.609 ± 0.066	3.612GluSer: 3.612 ± 0.059	3.698GluThr: 3.698 ± 0.054	4.813GluVal: 4.813 ± 0.069	0.73GluTrp: 0.73 ± 0.025	2.307GluTyr: 2.307 ± 0.041	0.0GluXaa: 0.0 ± 0.0
Phe	3.278PheAla: 3.278 ± 0.058	0.375PheCys: 0.375 ± 0.019	3.038PheAsp: 3.038 ± 0.051	3.058PheGlu: 3.058 ± 0.054	2.306PhePhe: 2.306 ± 0.069	3.826PheGly: 3.826 ± 0.062	0.802PheHis: 0.802 ± 0.031	2.584PheIle: 2.584 ± 0.056	1.889PheLys: 1.889 ± 0.05	4.579PheLeu: 4.579 ± 0.082	1.025PheMet: 1.025 ± 0.033	2.141PheAsn: 2.141 ± 0.05	1.964PhePro: 1.964 ± 0.042	1.488PheGln: 1.488 ± 0.047	3.161PheArg: 3.161 ± 0.053	3.145PheSer: 3.145 ± 0.058	2.746PheThr: 2.746 ± 0.063	2.617PheVal: 2.617 ± 0.052	0.629PheTrp: 0.629 ± 0.027	1.793PheTyr: 1.793 ± 0.044	0.0PheXaa: 0.0 ± 0.0
Gly	5.885GlyAla: 5.885 ± 0.103	0.765GlyCys: 0.765 ± 0.041	4.474GlyAsp: 4.474 ± 0.081	4.951GlyGlu: 4.951 ± 0.069	3.897GlyPhe: 3.897 ± 0.06	6.199GlyGly: 6.199 ± 0.107	1.511GlyHis: 1.511 ± 0.042	5.434GlyIle: 5.434 ± 0.075	4.307GlyLys: 4.307 ± 0.069	7.525GlyLeu: 7.525 ± 0.097	2.176GlyMet: 2.176 ± 0.051	3.64GlyAsn: 3.64 ± 0.099	2.533GlyPro: 2.533 ± 0.061	2.734GlyGln: 2.734 ± 0.05	4.061GlyArg: 4.061 ± 0.072	5.017GlySer: 5.017 ± 0.094	4.825GlyThr: 4.825 ± 0.115	5.223GlyVal: 5.223 ± 0.091	1.09GlyTrp: 1.09 ± 0.038	3.166GlyTyr: 3.166 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	1.381HisAla: 1.381 ± 0.035	0.204HisCys: 0.204 ± 0.014	0.793HisAsp: 0.793 ± 0.03	0.98HisGlu: 0.98 ± 0.029	1.078HisPhe: 1.078 ± 0.033	1.379HisGly: 1.379 ± 0.039	0.489HisHis: 0.489 ± 0.026	1.202HisIle: 1.202 ± 0.035	0.847HisLys: 0.847 ± 0.032	2.103HisLeu: 2.103 ± 0.05	0.419HisMet: 0.419 ± 0.019	0.722HisAsn: 0.722 ± 0.026	1.298HisPro: 1.298 ± 0.037	0.727HisGln: 0.727 ± 0.026	1.192HisArg: 1.192 ± 0.035	1.023HisSer: 1.023 ± 0.035	1.034HisThr: 1.034 ± 0.031	1.069HisVal: 1.069 ± 0.033	0.301HisTrp: 0.301 ± 0.015	0.843HisTyr: 0.843 ± 0.03	0.0HisXaa: 0.0 ± 0.0
Ile	5.209IleAla: 5.209 ± 0.076	0.571IleCys: 0.571 ± 0.021	3.728IleAsp: 3.728 ± 0.067	3.79IleGlu: 3.79 ± 0.071	2.558IlePhe: 2.558 ± 0.056	4.697IleGly: 4.697 ± 0.078	1.222IleHis: 1.222 ± 0.037	3.162IleIle: 3.162 ± 0.07	2.335IleLys: 2.335 ± 0.055	6.013IleLeu: 6.013 ± 0.088	0.988IleMet: 0.988 ± 0.036	2.469IleAsn: 2.469 ± 0.049	3.262IlePro: 3.262 ± 0.063	2.006IleGln: 2.006 ± 0.049	4.478IleArg: 4.478 ± 0.078	3.979IleSer: 3.979 ± 0.066	3.351IleThr: 3.351 ± 0.061	3.639IleVal: 3.639 ± 0.072	0.669IleTrp: 0.669 ± 0.026	2.094IleTyr: 2.094 ± 0.048	0.0IleXaa: 0.0 ± 0.0
Lys	3.859LysAla: 3.859 ± 0.077	0.213LysCys: 0.213 ± 0.014	2.622LysAsp: 2.622 ± 0.053	3.38LysGlu: 3.38 ± 0.074	1.679LysPhe: 1.679 ± 0.041	3.371LysGly: 3.371 ± 0.064	0.899LysHis: 0.899 ± 0.03	3.044LysIle: 3.044 ± 0.065	3.504LysLys: 3.504 ± 0.082	4.24LysLeu: 4.24 ± 0.077	1.243LysMet: 1.243 ± 0.041	2.207LysAsn: 2.207 ± 0.051	2.019LysPro: 2.019 ± 0.051	1.66LysGln: 1.66 ± 0.042	2.605LysArg: 2.605 ± 0.061	2.763LysSer: 2.763 ± 0.066	2.679LysThr: 2.679 ± 0.059	2.912LysVal: 2.912 ± 0.062	0.552LysTrp: 0.552 ± 0.022	1.72LysTyr: 1.72 ± 0.039	0.0LysXaa: 0.0 ± 0.0
Leu	8.416LeuAla: 8.416 ± 0.125	0.711LeuCys: 0.711 ± 0.028	5.77LeuAsp: 5.77 ± 0.087	7.736LeuGlu: 7.736 ± 0.111	4.462LeuPhe: 4.462 ± 0.082	7.474LeuGly: 7.474 ± 0.108	1.793LeuHis: 1.793 ± 0.053	5.532LeuIle: 5.532 ± 0.096	4.944LeuLys: 4.944 ± 0.082	10.261LeuLeu: 10.261 ± 0.168	2.242LeuMet: 2.242 ± 0.049	3.917LeuAsn: 3.917 ± 0.063	4.632LeuPro: 4.632 ± 0.073	3.684LeuGln: 3.684 ± 0.06	5.644LeuArg: 5.644 ± 0.093	6.446LeuSer: 6.446 ± 0.122	5.126LeuThr: 5.126 ± 0.102	6.414LeuVal: 6.414 ± 0.091	1.047LeuTrp: 1.047 ± 0.039	3.126LeuTyr: 3.126 ± 0.053	0.0LeuXaa: 0.0 ± 0.0
Met	2.099MetAla: 2.099 ± 0.048	0.126MetCys: 0.126 ± 0.011	1.463MetAsp: 1.463 ± 0.041	1.874MetGlu: 1.874 ± 0.043	0.659MetPhe: 0.659 ± 0.026	1.832MetGly: 1.832 ± 0.046	0.461MetHis: 0.461 ± 0.023	1.224MetIle: 1.224 ± 0.035	1.624MetLys: 1.624 ± 0.045	2.022MetLeu: 2.022 ± 0.049	0.569MetMet: 0.569 ± 0.029	0.983MetAsn: 0.983 ± 0.028	1.06MetPro: 1.06 ± 0.034	0.967MetGln: 0.967 ± 0.033	1.256MetArg: 1.256 ± 0.036	1.257MetSer: 1.257 ± 0.036	1.105MetThr: 1.105 ± 0.034	1.427MetVal: 1.427 ± 0.046	0.165MetTrp: 0.165 ± 0.011	0.615MetTyr: 0.615 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	3.145AsnAla: 3.145 ± 0.055	0.323AsnCys: 0.323 ± 0.02	2.097AsnAsp: 2.097 ± 0.067	2.175AsnGlu: 2.175 ± 0.058	2.057AsnPhe: 2.057 ± 0.05	3.253AsnGly: 3.253 ± 0.089	0.783AsnHis: 0.783 ± 0.028	2.604AsnIle: 2.604 ± 0.053	1.713AsnLys: 1.713 ± 0.049	4.227AsnLeu: 4.227 ± 0.077	0.959AsnMet: 0.959 ± 0.031	1.806AsnAsn: 1.806 ± 0.058	2.799AsnPro: 2.799 ± 0.059	1.607AsnGln: 1.607 ± 0.047	2.819AsnArg: 2.819 ± 0.051	2.478AsnSer: 2.478 ± 0.053	2.562AsnThr: 2.562 ± 0.101	2.268AsnVal: 2.268 ± 0.055	0.631AsnTrp: 0.631 ± 0.027	1.745AsnTyr: 1.745 ± 0.043	0.0AsnXaa: 0.0 ± 0.0
Pro	3.841ProAla: 3.841 ± 0.07	0.25ProCys: 0.25 ± 0.016	3.615ProAsp: 3.615 ± 0.083	4.56ProGlu: 4.56 ± 0.069	1.997ProPhe: 1.997 ± 0.036	4.374ProGly: 4.374 ± 0.085	0.799ProHis: 0.799 ± 0.027	2.242ProIle: 2.242 ± 0.046	1.687ProLys: 1.687 ± 0.04	3.856ProLeu: 3.856 ± 0.06	0.998ProMet: 0.998 ± 0.03	1.763ProAsn: 1.763 ± 0.046	1.683ProPro: 1.683 ± 0.058	1.362ProGln: 1.362 ± 0.035	1.896ProArg: 1.896 ± 0.044	2.216ProSer: 2.216 ± 0.056	2.045ProThr: 2.045 ± 0.052	3.564ProVal: 3.564 ± 0.066	0.554ProTrp: 0.554 ± 0.028	1.646ProTyr: 1.646 ± 0.042	0.0ProXaa: 0.0 ± 0.0
Gln	3.219GlnAla: 3.219 ± 0.066	0.176GlnCys: 0.176 ± 0.014	1.825GlnAsp: 1.825 ± 0.047	2.606GlnGlu: 2.606 ± 0.058	1.497GlnPhe: 1.497 ± 0.036	2.394GlnGly: 2.394 ± 0.045	0.618GlnHis: 0.618 ± 0.025	2.136GlnIle: 2.136 ± 0.049	1.743GlnLys: 1.743 ± 0.045	3.662GlnLeu: 3.662 ± 0.064	0.883GlnMet: 0.883 ± 0.03	1.458GlnAsn: 1.458 ± 0.047	1.723GlnPro: 1.723 ± 0.044	1.638GlnGln: 1.638 ± 0.047	1.931GlnArg: 1.931 ± 0.05	1.812GlnSer: 1.812 ± 0.039	1.852GlnThr: 1.852 ± 0.046	2.52GlnVal: 2.52 ± 0.049	0.499GlnTrp: 0.499 ± 0.023	1.194GlnTyr: 1.194 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	4.161ArgAla: 4.161 ± 0.073	0.312ArgCys: 0.312 ± 0.019	3.552ArgAsp: 3.552 ± 0.074	5.351ArgGlu: 5.351 ± 0.089	2.82ArgPhe: 2.82 ± 0.06	3.526ArgGly: 3.526 ± 0.065	1.203ArgHis: 1.203 ± 0.031	4.189ArgIle: 4.189 ± 0.061	3.452ArgLys: 3.452 ± 0.063	5.616ArgLeu: 5.616 ± 0.098	1.609ArgMet: 1.609 ± 0.039	2.692ArgAsn: 2.692 ± 0.053	2.163ArgPro: 2.163 ± 0.052	2.438ArgGln: 2.438 ± 0.05	3.126ArgArg: 3.126 ± 0.073	3.102ArgSer: 3.102 ± 0.062	2.798ArgThr: 2.798 ± 0.049	3.795ArgVal: 3.795 ± 0.056	0.721ArgTrp: 0.721 ± 0.028	2.376ArgTyr: 2.376 ± 0.054	0.0ArgXaa: 0.0 ± 0.0
Ser	4.29SerAla: 4.29 ± 0.058	0.515SerCys: 0.515 ± 0.021	3.608SerAsp: 3.608 ± 0.061	3.793SerGlu: 3.793 ± 0.067	2.797SerPhe: 2.797 ± 0.06	6.178SerGly: 6.178 ± 0.102	1.104SerHis: 1.104 ± 0.042	3.319SerIle: 3.319 ± 0.055	2.52SerLys: 2.52 ± 0.055	6.274SerLeu: 6.274 ± 0.104	1.267SerMet: 1.267 ± 0.034	2.361SerAsn: 2.361 ± 0.059	2.636SerPro: 2.636 ± 0.056	2.031SerGln: 2.031 ± 0.043	3.792SerArg: 3.792 ± 0.069	3.197SerSer: 3.197 ± 0.071	2.794SerThr: 2.794 ± 0.055	3.817SerVal: 3.817 ± 0.073	0.745SerTrp: 0.745 ± 0.028	2.255SerTyr: 2.255 ± 0.052	0.0SerXaa: 0.0 ± 0.0
Thr	4.505ThrAla: 4.505 ± 0.089	0.377ThrCys: 0.377 ± 0.027	3.531ThrAsp: 3.531 ± 0.116	3.173ThrGlu: 3.173 ± 0.058	2.445ThrPhe: 2.445 ± 0.054	5.047ThrGly: 5.047 ± 0.093	0.996ThrHis: 0.996 ± 0.03	3.209ThrIle: 3.209 ± 0.061	1.665ThrLys: 1.665 ± 0.048	5.475ThrLeu: 5.475 ± 0.106	0.898ThrMet: 0.898 ± 0.029	1.977ThrAsn: 1.977 ± 0.07	2.838ThrPro: 2.838 ± 0.057	1.605ThrGln: 1.605 ± 0.043	3.111ThrArg: 3.111 ± 0.052	2.991ThrSer: 2.991 ± 0.06	2.77ThrThr: 2.77 ± 0.067	3.861ThrVal: 3.861 ± 0.1	0.629ThrTrp: 0.629 ± 0.03	2.245ThrTyr: 2.245 ± 0.063	0.0ThrXaa: 0.0 ± 0.0
Val	5.475ValAla: 5.475 ± 0.085	0.562ValCys: 0.562 ± 0.022	3.758ValAsp: 3.758 ± 0.082	3.951ValGlu: 3.951 ± 0.067	3.195ValPhe: 3.195 ± 0.058	4.389ValGly: 4.389 ± 0.069	1.199ValHis: 1.199 ± 0.035	3.939ValIle: 3.939 ± 0.06	2.724ValLys: 2.724 ± 0.056	6.719ValLeu: 6.719 ± 0.088	1.382ValMet: 1.382 ± 0.038	2.689ValAsn: 2.689 ± 0.065	3.058ValPro: 3.058 ± 0.053	1.972ValGln: 1.972 ± 0.044	4.023ValArg: 4.023 ± 0.07	4.319ValSer: 4.319 ± 0.069	3.575ValThr: 3.575 ± 0.107	4.718ValVal: 4.718 ± 0.078	0.679ValTrp: 0.679 ± 0.025	2.349ValTyr: 2.349 ± 0.055	0.0ValXaa: 0.0 ± 0.0
Trp	0.806TrpAla: 0.806 ± 0.03	0.086TrpCys: 0.086 ± 0.009	0.796TrpAsp: 0.796 ± 0.031	0.887TrpGlu: 0.887 ± 0.032	0.61TrpPhe: 0.61 ± 0.025	0.882TrpGly: 0.882 ± 0.033	0.284TrpHis: 0.284 ± 0.018	0.773TrpIle: 0.773 ± 0.029	0.713TrpLys: 0.713 ± 0.022	1.202TrpLeu: 1.202 ± 0.039	0.383TrpMet: 0.383 ± 0.018	0.585TrpAsn: 0.585 ± 0.026	0.401TrpPro: 0.401 ± 0.02	0.498TrpGln: 0.498 ± 0.023	0.615TrpArg: 0.615 ± 0.025	0.651TrpSer: 0.651 ± 0.024	0.623TrpThr: 0.623 ± 0.026	0.853TrpVal: 0.853 ± 0.028	0.179TrpTrp: 0.179 ± 0.014	0.453TrpTyr: 0.453 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.702TyrAla: 2.702 ± 0.052	0.311TyrCys: 0.311 ± 0.017	2.197TyrAsp: 2.197 ± 0.053	2.256TyrGlu: 2.256 ± 0.04	2.078TyrPhe: 2.078 ± 0.051	2.827TyrGly: 2.827 ± 0.057	0.812TyrHis: 0.812 ± 0.028	1.909TyrIle: 1.909 ± 0.037	1.594TyrLys: 1.594 ± 0.042	3.997TyrLeu: 3.997 ± 0.065	0.769TyrMet: 0.769 ± 0.025	1.689TyrAsn: 1.689 ± 0.045	1.643TyrPro: 1.643 ± 0.043	1.496TyrGln: 1.496 ± 0.042	2.745TyrArg: 2.745 ± 0.057	2.193TyrSer: 2.193 ± 0.05	2.089TyrThr: 2.089 ± 0.065	2.029TyrVal: 2.029 ± 0.042	0.509TyrTrp: 0.509 ± 0.024	1.608TyrTyr: 1.608 ± 0.038	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3211 proteins (1075592 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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