Amino acid dipepetide frequency for Budgerigar fledgling disease virus (BFPyV) (Aves polyomavirus 1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.985AlaAla: 5.985 ± 1.898
0.544AlaCys: 0.544 ± 0.477
3.264AlaAsp: 3.264 ± 1.365
4.353AlaGlu: 4.353 ± 1.502
5.441AlaPhe: 5.441 ± 1.519
3.264AlaGly: 3.264 ± 1.845
2.176AlaHis: 2.176 ± 0.904
4.353AlaIle: 4.353 ± 1.879
1.632AlaLys: 1.632 ± 0.83
10.881AlaLeu: 10.881 ± 2.485
1.632AlaMet: 1.632 ± 0.572
1.632AlaAsn: 1.632 ± 1.05
2.72AlaPro: 2.72 ± 1.789
4.897AlaGln: 4.897 ± 1.663
5.441AlaArg: 5.441 ± 1.013
3.808AlaSer: 3.808 ± 1.092
3.264AlaThr: 3.264 ± 1.439
8.705AlaVal: 8.705 ± 3.093
1.088AlaTrp: 1.088 ± 0.674
2.176AlaTyr: 2.176 ± 0.788
0.0AlaXaa: 0.0 ± 0.0
Cys
2.72CysAla: 2.72 ± 0.921
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.544CysGly: 0.544 ± 0.477
0.544CysHis: 0.544 ± 0.376
0.0CysIle: 0.0 ± 0.0
1.088CysLys: 1.088 ± 0.484
1.088CysLeu: 1.088 ± 0.653
1.632CysMet: 1.632 ± 0.644
0.0CysAsn: 0.0 ± 0.0
2.72CysPro: 2.72 ± 1.344
1.088CysGln: 1.088 ± 0.751
0.0CysArg: 0.0 ± 0.0
1.088CysSer: 1.088 ± 0.751
1.632CysThr: 1.632 ± 1.127
1.088CysVal: 1.088 ± 0.751
0.544CysTrp: 0.544 ± 0.477
0.544CysTyr: 0.544 ± 0.477
0.0CysXaa: 0.0 ± 0.0
Asp
3.264AspAla: 3.264 ± 0.804
1.088AspCys: 1.088 ± 0.751
1.632AspAsp: 1.632 ± 0.723
4.353AspGlu: 4.353 ± 1.876
1.632AspPhe: 1.632 ± 0.734
2.72AspGly: 2.72 ± 0.965
1.088AspHis: 1.088 ± 0.751
7.617AspIle: 7.617 ± 1.912
2.72AspLys: 2.72 ± 1.053
4.353AspLeu: 4.353 ± 0.853
1.088AspMet: 1.088 ± 0.484
0.544AspAsn: 0.544 ± 0.376
2.176AspPro: 2.176 ± 0.595
2.72AspGln: 2.72 ± 0.473
0.544AspArg: 0.544 ± 0.376
2.72AspSer: 2.72 ± 0.534
2.72AspThr: 2.72 ± 0.473
4.897AspVal: 4.897 ± 0.877
1.088AspTrp: 1.088 ± 0.674
0.544AspTyr: 0.544 ± 0.376
0.0AspXaa: 0.0 ± 0.0
Glu
3.264GluAla: 3.264 ± 0.829
1.632GluCys: 1.632 ± 0.723
3.264GluAsp: 3.264 ± 1.194
5.441GluGlu: 5.441 ± 1.68
1.632GluPhe: 1.632 ± 0.876
6.529GluGly: 6.529 ± 1.131
0.544GluHis: 0.544 ± 0.376
2.176GluIle: 2.176 ± 0.77
3.264GluLys: 3.264 ± 1.866
6.529GluLeu: 6.529 ± 2.327
2.176GluMet: 2.176 ± 0.757
2.72GluAsn: 2.72 ± 0.965
2.176GluPro: 2.176 ± 0.788
2.72GluGln: 2.72 ± 1.192
7.073GluArg: 7.073 ± 0.848
1.632GluSer: 1.632 ± 0.876
5.985GluThr: 5.985 ± 0.978
3.808GluVal: 3.808 ± 1.602
2.176GluTrp: 2.176 ± 1.347
0.544GluTyr: 0.544 ± 0.607
0.0GluXaa: 0.0 ± 0.0
Phe
0.544PheAla: 0.544 ± 0.502
0.544PheCys: 0.544 ± 0.376
0.544PheAsp: 0.544 ± 0.502
4.897PheGlu: 4.897 ± 1.524
3.808PhePhe: 3.808 ± 0.979
1.088PheGly: 1.088 ± 0.751
0.0PheHis: 0.0 ± 0.0
0.544PheIle: 0.544 ± 0.502
2.72PheLys: 2.72 ± 1.499
1.632PheLeu: 1.632 ± 0.723
1.632PheMet: 1.632 ± 0.854
1.632PheAsn: 1.632 ± 0.885
2.176PhePro: 2.176 ± 0.694
2.176PheGln: 2.176 ± 0.992
4.353PheArg: 4.353 ± 0.738
4.353PheSer: 4.353 ± 1.009
1.632PheThr: 1.632 ± 1.034
0.544PheVal: 0.544 ± 0.376
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
5.985GlyAla: 5.985 ± 1.642
0.544GlyCys: 0.544 ± 0.376
3.264GlyAsp: 3.264 ± 0.788
3.808GlyGlu: 3.808 ± 1.141
1.088GlyPhe: 1.088 ± 0.484
5.441GlyGly: 5.441 ± 1.89
0.544GlyHis: 0.544 ± 0.376
4.353GlyIle: 4.353 ± 0.991
2.176GlyLys: 2.176 ± 0.451
8.705GlyLeu: 8.705 ± 1.683
1.088GlyMet: 1.088 ± 0.484
2.72GlyAsn: 2.72 ± 1.161
4.353GlyPro: 4.353 ± 2.066
4.897GlyGln: 4.897 ± 2.19
4.353GlyArg: 4.353 ± 1.977
1.632GlySer: 1.632 ± 0.885
3.808GlyThr: 3.808 ± 0.675
2.176GlyVal: 2.176 ± 0.966
0.0GlyTrp: 0.0 ± 0.0
3.264GlyTyr: 3.264 ± 1.764
0.0GlyXaa: 0.0 ± 0.0
His
2.176HisAla: 2.176 ± 0.694
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
2.176HisGlu: 2.176 ± 0.694
1.088HisPhe: 1.088 ± 0.484
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
2.176HisIle: 2.176 ± 1.502
0.0HisLys: 0.0 ± 0.0
3.808HisLeu: 3.808 ± 1.691
0.0HisMet: 0.0 ± 0.0
2.176HisAsn: 2.176 ± 0.694
1.632HisPro: 1.632 ± 0.876
3.264HisGln: 3.264 ± 0.801
0.0HisArg: 0.0 ± 0.0
1.088HisSer: 1.088 ± 0.955
0.544HisThr: 0.544 ± 0.376
0.0HisVal: 0.0 ± 0.0
0.544HisTrp: 0.544 ± 0.376
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.632IleAla: 1.632 ± 0.92
1.088IleCys: 1.088 ± 0.484
4.353IleAsp: 4.353 ± 2.066
6.529IleGlu: 6.529 ± 2.274
2.72IlePhe: 2.72 ± 0.884
3.264IleGly: 3.264 ± 1.545
1.632IleHis: 1.632 ± 0.682
1.088IleIle: 1.088 ± 0.492
3.808IleLys: 3.808 ± 2.225
5.985IleLeu: 5.985 ± 1.322
0.0IleMet: 0.0 ± 0.0
1.632IleAsn: 1.632 ± 0.682
1.088IlePro: 1.088 ± 0.553
2.72IleGln: 2.72 ± 0.473
2.176IleArg: 2.176 ± 0.992
2.72IleSer: 2.72 ± 1.38
4.897IleThr: 4.897 ± 1.606
2.176IleVal: 2.176 ± 0.694
1.088IleTrp: 1.088 ± 0.674
1.632IleTyr: 1.632 ± 0.572
0.0IleXaa: 0.0 ± 0.0
Lys
4.353LysAla: 4.353 ± 0.572
1.632LysCys: 1.632 ± 0.876
2.176LysAsp: 2.176 ± 1.045
3.264LysGlu: 3.264 ± 0.97
0.544LysPhe: 0.544 ± 0.376
4.897LysGly: 4.897 ± 1.834
1.088LysHis: 1.088 ± 0.751
0.0LysIle: 0.0 ± 0.0
3.264LysLys: 3.264 ± 0.97
3.264LysLeu: 3.264 ± 1.194
2.176LysMet: 2.176 ± 0.993
2.176LysAsn: 2.176 ± 0.968
1.088LysPro: 1.088 ± 0.751
1.632LysGln: 1.632 ± 0.876
8.161LysArg: 8.161 ± 2.112
1.632LysSer: 1.632 ± 0.682
3.264LysThr: 3.264 ± 1.133
2.72LysVal: 2.72 ± 0.766
0.0LysTrp: 0.0 ± 0.0
1.632LysTyr: 1.632 ± 0.876
0.0LysXaa: 0.0 ± 0.0
Leu
10.337LeuAla: 10.337 ± 2.591
3.264LeuCys: 3.264 ± 1.371
5.985LeuAsp: 5.985 ± 2.3
7.617LeuGlu: 7.617 ± 1.643
6.529LeuPhe: 6.529 ± 0.482
3.808LeuGly: 3.808 ± 1.518
3.264LeuHis: 3.264 ± 1.654
7.073LeuIle: 7.073 ± 1.346
5.985LeuLys: 5.985 ± 1.707
18.498LeuLeu: 18.498 ± 8.269
3.264LeuMet: 3.264 ± 1.289
4.897LeuAsn: 4.897 ± 0.798
8.161LeuPro: 8.161 ± 2.132
4.897LeuGln: 4.897 ± 0.89
7.617LeuArg: 7.617 ± 2.531
1.088LeuSer: 1.088 ± 0.553
6.529LeuThr: 6.529 ± 2.095
2.176LeuVal: 2.176 ± 0.547
0.0LeuTrp: 0.0 ± 0.0
3.808LeuTyr: 3.808 ± 0.913
0.0LeuXaa: 0.0 ± 0.0
Met
2.176MetAla: 2.176 ± 0.716
0.0MetCys: 0.0 ± 0.0
1.088MetAsp: 1.088 ± 0.674
1.632MetGlu: 1.632 ± 0.644
0.544MetPhe: 0.544 ± 0.607
0.544MetGly: 0.544 ± 0.502
1.088MetHis: 1.088 ± 0.484
0.0MetIle: 0.0 ± 0.0
2.176MetLys: 2.176 ± 1.307
1.088MetLeu: 1.088 ± 0.751
0.0MetMet: 0.0 ± 0.0
1.088MetAsn: 1.088 ± 0.751
2.72MetPro: 2.72 ± 1.213
3.264MetGln: 3.264 ± 0.716
0.0MetArg: 0.0 ± 0.0
0.544MetSer: 0.544 ± 0.477
3.808MetThr: 3.808 ± 1.141
1.632MetVal: 1.632 ± 1.127
0.544MetTrp: 0.544 ± 0.477
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.632AsnAla: 1.632 ± 0.572
0.544AsnCys: 0.544 ± 0.376
2.176AsnAsp: 2.176 ± 0.966
1.632AsnGlu: 1.632 ± 0.644
1.088AsnPhe: 1.088 ± 0.751
3.264AsnGly: 3.264 ± 1.596
0.0AsnHis: 0.0 ± 0.0
3.264AsnIle: 3.264 ± 1.143
0.544AsnLys: 0.544 ± 0.376
3.264AsnLeu: 3.264 ± 1.755
1.632AsnMet: 1.632 ± 0.659
2.176AsnAsn: 2.176 ± 1.034
2.176AsnPro: 2.176 ± 0.451
0.0AsnGln: 0.0 ± 0.0
2.72AsnArg: 2.72 ± 2.199
1.088AsnSer: 1.088 ± 0.955
3.808AsnThr: 3.808 ± 0.814
3.808AsnVal: 3.808 ± 0.666
0.0AsnTrp: 0.0 ± 0.0
1.632AsnTyr: 1.632 ± 0.572
0.0AsnXaa: 0.0 ± 0.0
Pro
2.72ProAla: 2.72 ± 1.247
0.544ProCys: 0.544 ± 0.477
5.441ProAsp: 5.441 ± 2.107
7.073ProGlu: 7.073 ± 1.921
0.0ProPhe: 0.0 ± 0.0
4.353ProGly: 4.353 ± 0.903
1.088ProHis: 1.088 ± 0.484
0.544ProIle: 0.544 ± 0.477
2.176ProLys: 2.176 ± 0.451
7.073ProLeu: 7.073 ± 3.096
0.544ProMet: 0.544 ± 0.592
2.176ProAsn: 2.176 ± 2.314
5.441ProPro: 5.441 ± 1.536
2.176ProGln: 2.176 ± 0.451
4.897ProArg: 4.897 ± 3.333
3.808ProSer: 3.808 ± 1.631
4.353ProThr: 4.353 ± 0.853
4.353ProVal: 4.353 ± 0.845
0.544ProTrp: 0.544 ± 0.607
0.544ProTyr: 0.544 ± 0.477
0.0ProXaa: 0.0 ± 0.0
Gln
3.264GlnAla: 3.264 ± 0.829
0.544GlnCys: 0.544 ± 0.376
3.264GlnAsp: 3.264 ± 1.424
1.632GlnGlu: 1.632 ± 0.572
1.632GlnPhe: 1.632 ± 1.127
2.72GlnGly: 2.72 ± 1.131
0.544GlnHis: 0.544 ± 0.376
2.176GlnIle: 2.176 ± 0.694
3.264GlnLys: 3.264 ± 0.65
2.72GlnLeu: 2.72 ± 0.473
1.088GlnMet: 1.088 ± 0.674
1.088GlnAsn: 1.088 ± 0.484
3.264GlnPro: 3.264 ± 2.258
2.72GlnGln: 2.72 ± 0.727
2.176GlnArg: 2.176 ± 0.451
4.353GlnSer: 4.353 ± 1.693
6.529GlnThr: 6.529 ± 2.024
3.808GlnVal: 3.808 ± 1.603
0.0GlnTrp: 0.0 ± 0.0
1.088GlnTyr: 1.088 ± 0.484
0.0GlnXaa: 0.0 ± 0.0
Arg
3.808ArgAla: 3.808 ± 0.666
0.0ArgCys: 0.0 ± 0.0
2.72ArgAsp: 2.72 ± 0.775
1.632ArgGlu: 1.632 ± 0.644
1.632ArgPhe: 1.632 ± 1.127
4.353ArgGly: 4.353 ± 1.25
1.632ArgHis: 1.632 ± 0.572
3.808ArgIle: 3.808 ± 1.064
5.985ArgLys: 5.985 ± 1.354
11.97ArgLeu: 11.97 ± 4.719
2.176ArgMet: 2.176 ± 0.952
2.176ArgAsn: 2.176 ± 0.968
3.808ArgPro: 3.808 ± 1.759
1.088ArgGln: 1.088 ± 0.932
7.617ArgArg: 7.617 ± 1.811
4.353ArgSer: 4.353 ± 1.172
4.897ArgThr: 4.897 ± 1.222
1.632ArgVal: 1.632 ± 0.682
1.088ArgTrp: 1.088 ± 0.674
4.897ArgTyr: 4.897 ± 1.663
0.0ArgXaa: 0.0 ± 0.0
Ser
3.808SerAla: 3.808 ± 1.037
2.72SerCys: 2.72 ± 1.213
2.72SerAsp: 2.72 ± 0.534
1.088SerGlu: 1.088 ± 0.653
1.088SerPhe: 1.088 ± 0.674
5.985SerGly: 5.985 ± 1.188
0.0SerHis: 0.0 ± 0.0
5.441SerIle: 5.441 ± 1.093
1.632SerLys: 1.632 ± 0.682
5.985SerLeu: 5.985 ± 1.203
0.544SerMet: 0.544 ± 0.477
1.088SerAsn: 1.088 ± 0.674
1.632SerPro: 1.632 ± 0.989
1.088SerGln: 1.088 ± 0.484
2.72SerArg: 2.72 ± 1.506
0.544SerSer: 0.544 ± 0.477
3.264SerThr: 3.264 ± 1.155
5.985SerVal: 5.985 ± 1.473
0.0SerTrp: 0.0 ± 0.0
1.088SerTyr: 1.088 ± 0.674
0.0SerXaa: 0.0 ± 0.0
Thr
11.97ThrAla: 11.97 ± 2.897
0.544ThrCys: 0.544 ± 0.477
1.088ThrAsp: 1.088 ± 0.751
3.808ThrGlu: 3.808 ± 1.39
1.088ThrPhe: 1.088 ± 0.653
5.441ThrGly: 5.441 ± 1.009
0.544ThrHis: 0.544 ± 0.376
4.353ThrIle: 4.353 ± 1.478
1.088ThrLys: 1.088 ± 0.751
8.705ThrLeu: 8.705 ± 1.444
1.632ThrMet: 1.632 ± 1.127
1.088ThrAsn: 1.088 ± 0.484
4.897ThrPro: 4.897 ± 0.986
1.632ThrGln: 1.632 ± 1.582
2.176ThrArg: 2.176 ± 0.89
6.529ThrSer: 6.529 ± 2.508
5.985ThrThr: 5.985 ± 1.983
4.897ThrVal: 4.897 ± 1.859
0.0ThrTrp: 0.0 ± 0.0
2.72ThrTyr: 2.72 ± 0.534
0.0ThrXaa: 0.0 ± 0.0
Val
4.353ValAla: 4.353 ± 1.502
0.0ValCys: 0.0 ± 0.0
4.897ValAsp: 4.897 ± 1.303
1.632ValGlu: 1.632 ± 0.682
0.0ValPhe: 0.0 ± 0.0
2.72ValGly: 2.72 ± 1.362
2.72ValHis: 2.72 ± 0.959
2.72ValIle: 2.72 ± 0.473
3.808ValLys: 3.808 ± 1.177
7.073ValLeu: 7.073 ± 1.263
0.0ValMet: 0.0 ± 0.0
4.353ValAsn: 4.353 ± 2.076
5.985ValPro: 5.985 ± 1.033
1.088ValGln: 1.088 ± 0.484
4.353ValArg: 4.353 ± 1.201
4.353ValSer: 4.353 ± 0.93
1.632ValThr: 1.632 ± 0.876
1.088ValVal: 1.088 ± 0.484
1.088ValTrp: 1.088 ± 0.674
2.72ValTyr: 2.72 ± 0.732
0.0ValXaa: 0.0 ± 0.0
Trp
1.088TrpAla: 1.088 ± 0.674
0.544TrpCys: 0.544 ± 0.477
0.0TrpAsp: 0.0 ± 0.0
0.544TrpGlu: 0.544 ± 0.477
1.088TrpPhe: 1.088 ± 0.674
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.544TrpLys: 0.544 ± 0.607
1.088TrpLeu: 1.088 ± 0.674
0.0TrpMet: 0.0 ± 0.0
1.088TrpAsn: 1.088 ± 0.674
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
2.72TrpArg: 2.72 ± 1.269
0.0TrpSer: 0.0 ± 0.0
1.632TrpThr: 1.632 ± 0.572
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.176TyrAla: 2.176 ± 1.179
0.544TyrCys: 0.544 ± 0.376
1.632TyrAsp: 1.632 ± 0.572
2.176TyrGlu: 2.176 ± 0.451
2.176TyrPhe: 2.176 ± 1.154
3.264TyrGly: 3.264 ± 1.365
2.176TyrHis: 2.176 ± 0.716
0.544TyrIle: 0.544 ± 0.376
1.088TyrLys: 1.088 ± 0.484
1.088TyrLeu: 1.088 ± 0.484
1.088TyrMet: 1.088 ± 0.674
0.544TyrAsn: 0.544 ± 0.376
1.632TyrPro: 1.632 ± 1.432
3.808TyrGln: 3.808 ± 1.914
2.176TyrArg: 2.176 ± 0.716
1.088TyrSer: 1.088 ± 0.955
0.0TyrThr: 0.0 ± 0.0
1.088TyrVal: 1.088 ± 0.484
0.544TyrTrp: 0.544 ± 0.477
2.176TyrTyr: 2.176 ± 0.451
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (1839 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski