Amino acid dipepetide frequency for Mycoplasma anatis 1340

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.606AlaAla: 2.606 ± 0.132
0.243AlaCys: 0.243 ± 0.028
2.004AlaAsp: 2.004 ± 0.093
2.667AlaGlu: 2.667 ± 0.129
2.156AlaPhe: 2.156 ± 0.093
2.269AlaGly: 2.269 ± 0.129
0.638AlaHis: 0.638 ± 0.054
4.682AlaIle: 4.682 ± 0.145
5.045AlaLys: 5.045 ± 0.156
4.548AlaLeu: 4.548 ± 0.16
0.924AlaMet: 0.924 ± 0.075
3.247AlaAsn: 3.247 ± 0.126
1.04AlaPro: 1.04 ± 0.065
1.45AlaGln: 1.45 ± 0.069
1.656AlaArg: 1.656 ± 0.086
2.899AlaSer: 2.899 ± 0.108
2.483AlaThr: 2.483 ± 0.114
2.327AlaVal: 2.327 ± 0.117
0.337AlaTrp: 0.337 ± 0.033
1.703AlaTyr: 1.703 ± 0.074
0.0AlaXaa: 0.0 ± 0.0
Cys
0.243CysAla: 0.243 ± 0.034
0.062CysCys: 0.062 ± 0.015
0.42CysAsp: 0.42 ± 0.041
0.42CysGlu: 0.42 ± 0.041
0.362CysPhe: 0.362 ± 0.037
0.402CysGly: 0.402 ± 0.037
0.112CysHis: 0.112 ± 0.022
0.486CysIle: 0.486 ± 0.048
0.41CysLys: 0.41 ± 0.039
0.638CysLeu: 0.638 ± 0.053
0.105CysMet: 0.105 ± 0.022
0.359CysAsn: 0.359 ± 0.039
0.178CysPro: 0.178 ± 0.025
0.12CysGln: 0.12 ± 0.022
0.159CysArg: 0.159 ± 0.023
0.497CysSer: 0.497 ± 0.048
0.21CysThr: 0.21 ± 0.031
0.312CysVal: 0.312 ± 0.034
0.036CysTrp: 0.036 ± 0.011
0.243CysTyr: 0.243 ± 0.034
0.0CysXaa: 0.0 ± 0.0
Asp
2.254AspAla: 2.254 ± 0.097
0.286AspCys: 0.286 ± 0.036
2.718AspAsp: 2.718 ± 0.108
4.49AspGlu: 4.49 ± 0.17
3.559AspPhe: 3.559 ± 0.118
2.287AspGly: 2.287 ± 0.12
0.609AspHis: 0.609 ± 0.046
4.983AspIle: 4.983 ± 0.141
5.933AspLys: 5.933 ± 0.156
5.331AspLeu: 5.331 ± 0.147
0.757AspMet: 0.757 ± 0.058
3.918AspAsn: 3.918 ± 0.142
1.457AspPro: 1.457 ± 0.073
1.602AspGln: 1.602 ± 0.096
1.337AspArg: 1.337 ± 0.068
3.461AspSer: 3.461 ± 0.115
2.327AspThr: 2.327 ± 0.1
2.968AspVal: 2.968 ± 0.103
0.522AspTrp: 0.522 ± 0.049
2.892AspTyr: 2.892 ± 0.128
0.0AspXaa: 0.0 ± 0.0
Glu
2.899GluAla: 2.899 ± 0.134
0.308GluCys: 0.308 ± 0.038
2.841GluAsp: 2.841 ± 0.106
5.19GluGlu: 5.19 ± 0.167
4.211GluPhe: 4.211 ± 0.139
2.193GluGly: 2.193 ± 0.105
0.852GluHis: 0.852 ± 0.052
8.292GluIle: 8.292 ± 0.197
7.488GluLys: 7.488 ± 0.186
8.154GluLeu: 8.154 ± 0.21
1.432GluMet: 1.432 ± 0.082
6.357GluAsn: 6.357 ± 0.168
1.294GluPro: 1.294 ± 0.075
2.638GluGln: 2.638 ± 0.112
2.059GluArg: 2.059 ± 0.095
3.544GluSer: 3.544 ± 0.125
3.233GluThr: 3.233 ± 0.12
3.94GluVal: 3.94 ± 0.158
0.558GluTrp: 0.558 ± 0.041
3.139GluTyr: 3.139 ± 0.12
0.0GluXaa: 0.0 ± 0.0
Phe
2.461PheAla: 2.461 ± 0.11
0.373PheCys: 0.373 ± 0.036
3.588PheAsp: 3.588 ± 0.124
3.602PheGlu: 3.602 ± 0.118
2.53PhePhe: 2.53 ± 0.099
2.533PheGly: 2.533 ± 0.097
0.529PheHis: 0.529 ± 0.051
5.933PheIle: 5.933 ± 0.211
4.603PheLys: 4.603 ± 0.141
4.788PheLeu: 4.788 ± 0.144
0.957PheMet: 0.957 ± 0.053
5.367PheAsn: 5.367 ± 0.189
1.134PhePro: 1.134 ± 0.061
1.116PheGln: 1.116 ± 0.06
1.551PheArg: 1.551 ± 0.076
4.153PheSer: 4.153 ± 0.149
2.704PheThr: 2.704 ± 0.112
3.226PheVal: 3.226 ± 0.131
0.529PheTrp: 0.529 ± 0.051
2.381PheTyr: 2.381 ± 0.119
0.0PheXaa: 0.0 ± 0.0
Gly
2.417GlyAla: 2.417 ± 0.123
0.239GlyCys: 0.239 ± 0.032
2.258GlyAsp: 2.258 ± 0.113
2.428GlyGlu: 2.428 ± 0.128
2.624GlyPhe: 2.624 ± 0.103
2.548GlyGly: 2.548 ± 0.144
0.699GlyHis: 0.699 ± 0.06
4.476GlyIle: 4.476 ± 0.156
4.008GlyLys: 4.008 ± 0.16
3.925GlyLeu: 3.925 ± 0.138
1.051GlyMet: 1.051 ± 0.074
2.276GlyAsn: 2.276 ± 0.112
0.819GlyPro: 0.819 ± 0.053
1.297GlyGln: 1.297 ± 0.072
1.479GlyArg: 1.479 ± 0.103
3.004GlySer: 3.004 ± 0.118
2.566GlyThr: 2.566 ± 0.111
3.019GlyVal: 3.019 ± 0.124
0.413GlyTrp: 0.413 ± 0.04
2.08GlyTyr: 2.08 ± 0.085
0.0GlyXaa: 0.0 ± 0.0
His
0.576HisAla: 0.576 ± 0.048
0.109HisCys: 0.109 ± 0.02
0.703HisAsp: 0.703 ± 0.06
0.968HisGlu: 0.968 ± 0.064
0.844HisPhe: 0.844 ± 0.056
0.728HisGly: 0.728 ± 0.057
0.246HisHis: 0.246 ± 0.032
1.192HisIle: 1.192 ± 0.072
1.116HisLys: 1.116 ± 0.063
1.268HisLeu: 1.268 ± 0.076
0.21HisMet: 0.21 ± 0.03
1.029HisAsn: 1.029 ± 0.054
0.511HisPro: 0.511 ± 0.045
0.399HisGln: 0.399 ± 0.037
0.37HisArg: 0.37 ± 0.04
0.964HisSer: 0.964 ± 0.056
0.536HisThr: 0.536 ± 0.05
0.602HisVal: 0.602 ± 0.048
0.134HisTrp: 0.134 ± 0.019
0.703HisTyr: 0.703 ± 0.049
0.0HisXaa: 0.0 ± 0.0
Ile
4.682IleAla: 4.682 ± 0.151
0.623IleCys: 0.623 ± 0.053
6.277IleAsp: 6.277 ± 0.166
6.694IleGlu: 6.694 ± 0.203
5.607IlePhe: 5.607 ± 0.228
4.24IleGly: 4.24 ± 0.161
1.326IleHis: 1.326 ± 0.075
9.256IleIle: 9.256 ± 0.325
10.572IleLys: 10.572 ± 0.263
8.796IleLeu: 8.796 ± 0.218
1.363IleMet: 1.363 ± 0.066
9.234IleAsn: 9.234 ± 0.257
2.729IlePro: 2.729 ± 0.099
3.015IleGln: 3.015 ± 0.107
2.624IleArg: 2.624 ± 0.113
8.466IleSer: 8.466 ± 0.213
5.277IleThr: 5.277 ± 0.147
5.458IleVal: 5.458 ± 0.16
0.844IleTrp: 0.844 ± 0.057
4.164IleTyr: 4.164 ± 0.147
0.0IleXaa: 0.0 ± 0.0
Lys
3.983LysAla: 3.983 ± 0.151
0.449LysCys: 0.449 ± 0.041
5.429LysAsp: 5.429 ± 0.146
7.575LysGlu: 7.575 ± 0.168
4.991LysPhe: 4.991 ± 0.153
3.352LysGly: 3.352 ± 0.114
1.381LysHis: 1.381 ± 0.08
11.192LysIle: 11.192 ± 0.254
9.35LysLys: 9.35 ± 0.216
9.8LysLeu: 9.8 ± 0.226
2.493LysMet: 2.493 ± 0.105
10.021LysAsn: 10.021 ± 0.27
2.04LysPro: 2.04 ± 0.106
3.323LysGln: 3.323 ± 0.123
2.994LysArg: 2.994 ± 0.117
5.944LysSer: 5.944 ± 0.15
5.491LysThr: 5.491 ± 0.144
5.371LysVal: 5.371 ± 0.168
0.931LysTrp: 0.931 ± 0.06
5.074LysTyr: 5.074 ± 0.159
0.004LysXaa: 0.004 ± 0.004
Leu
4.574LeuAla: 4.574 ± 0.152
0.587LeuCys: 0.587 ± 0.047
5.088LeuAsp: 5.088 ± 0.137
6.462LeuGlu: 6.462 ± 0.161
4.762LeuPhe: 4.762 ± 0.159
4.11LeuGly: 4.11 ± 0.146
1.279LeuHis: 1.279 ± 0.075
10.742LeuIle: 10.742 ± 0.279
9.372LeuLys: 9.372 ± 0.231
8.31LeuLeu: 8.31 ± 0.213
1.624LeuMet: 1.624 ± 0.079
8.579LeuAsn: 8.579 ± 0.249
2.425LeuPro: 2.425 ± 0.098
2.388LeuGln: 2.388 ± 0.096
2.925LeuArg: 2.925 ± 0.108
7.477LeuSer: 7.477 ± 0.158
5.215LeuThr: 5.215 ± 0.15
5.715LeuVal: 5.715 ± 0.166
0.696LeuTrp: 0.696 ± 0.047
3.229LeuTyr: 3.229 ± 0.11
0.0LeuXaa: 0.0 ± 0.0
Met
0.819MetAla: 0.819 ± 0.061
0.101MetCys: 0.101 ± 0.02
0.91MetAsp: 0.91 ± 0.071
0.939MetGlu: 0.939 ± 0.071
0.942MetPhe: 0.942 ± 0.059
0.699MetGly: 0.699 ± 0.058
0.272MetHis: 0.272 ± 0.031
2.019MetIle: 2.019 ± 0.097
1.874MetLys: 1.874 ± 0.086
1.656MetLeu: 1.656 ± 0.087
0.381MetMet: 0.381 ± 0.041
1.664MetAsn: 1.664 ± 0.085
0.555MetPro: 0.555 ± 0.048
0.468MetGln: 0.468 ± 0.047
0.612MetArg: 0.612 ± 0.05
1.345MetSer: 1.345 ± 0.077
0.783MetThr: 0.783 ± 0.063
0.931MetVal: 0.931 ± 0.064
0.109MetTrp: 0.109 ± 0.02
0.547MetTyr: 0.547 ± 0.041
0.0MetXaa: 0.0 ± 0.0
Asn
3.207AsnAla: 3.207 ± 0.126
0.399AsnCys: 0.399 ± 0.045
4.664AsnAsp: 4.664 ± 0.152
6.375AsnGlu: 6.375 ± 0.2
4.287AsnPhe: 4.287 ± 0.163
3.457AsnGly: 3.457 ± 0.116
1.066AsnHis: 1.066 ± 0.079
8.14AsnIle: 8.14 ± 0.184
9.887AsnLys: 9.887 ± 0.217
8.067AsnLeu: 8.067 ± 0.255
1.203AsnMet: 1.203 ± 0.077
8.006AsnAsn: 8.006 ± 0.333
2.475AsnPro: 2.475 ± 0.121
2.932AsnGln: 2.932 ± 0.137
2.222AsnArg: 2.222 ± 0.083
6.411AsnSer: 6.411 ± 0.229
3.838AsnThr: 3.838 ± 0.15
4.001AsnVal: 4.001 ± 0.119
0.837AsnTrp: 0.837 ± 0.056
3.94AsnTyr: 3.94 ± 0.143
0.0AsnXaa: 0.0 ± 0.0
Pro
1.105ProAla: 1.105 ± 0.075
0.109ProCys: 0.109 ± 0.017
1.102ProAsp: 1.102 ± 0.058
2.258ProGlu: 2.258 ± 0.116
1.366ProPhe: 1.366 ± 0.082
1.272ProGly: 1.272 ± 0.082
0.442ProHis: 0.442 ± 0.041
2.265ProIle: 2.265 ± 0.084
2.135ProLys: 2.135 ± 0.081
1.928ProLeu: 1.928 ± 0.086
0.373ProMet: 0.373 ± 0.038
1.964ProAsn: 1.964 ± 0.091
0.377ProPro: 0.377 ± 0.036
0.667ProGln: 0.667 ± 0.053
0.703ProArg: 0.703 ± 0.053
1.899ProSer: 1.899 ± 0.095
1.58ProThr: 1.58 ± 0.086
1.461ProVal: 1.461 ± 0.088
0.268ProTrp: 0.268 ± 0.029
1.134ProTyr: 1.134 ± 0.073
0.0ProXaa: 0.0 ± 0.0
Gln
1.548GlnAla: 1.548 ± 0.087
0.105GlnCys: 0.105 ± 0.021
1.276GlnAsp: 1.276 ± 0.064
2.073GlnGlu: 2.073 ± 0.1
1.5GlnPhe: 1.5 ± 0.083
1.095GlnGly: 1.095 ± 0.067
0.359GlnHis: 0.359 ± 0.035
3.139GlnIle: 3.139 ± 0.107
3.418GlnLys: 3.418 ± 0.11
2.874GlnLeu: 2.874 ± 0.14
0.605GlnMet: 0.605 ± 0.045
2.99GlnAsn: 2.99 ± 0.129
0.743GlnPro: 0.743 ± 0.064
0.957GlnGln: 0.957 ± 0.064
1.029GlnArg: 1.029 ± 0.061
1.819GlnSer: 1.819 ± 0.091
1.475GlnThr: 1.475 ± 0.072
1.533GlnVal: 1.533 ± 0.081
0.301GlnTrp: 0.301 ± 0.038
1.171GlnTyr: 1.171 ± 0.071
0.0GlnXaa: 0.0 ± 0.0
Arg
1.45ArgAla: 1.45 ± 0.076
0.145ArgCys: 0.145 ± 0.021
1.609ArgAsp: 1.609 ± 0.08
2.381ArgGlu: 2.381 ± 0.101
1.522ArgPhe: 1.522 ± 0.078
1.334ArgGly: 1.334 ± 0.091
0.366ArgHis: 0.366 ± 0.037
2.888ArgIle: 2.888 ± 0.119
2.983ArgLys: 2.983 ± 0.125
2.584ArgLeu: 2.584 ± 0.096
0.634ArgMet: 0.634 ± 0.051
2.392ArgAsn: 2.392 ± 0.092
0.75ArgPro: 0.75 ± 0.058
0.873ArgGln: 0.873 ± 0.062
1.138ArgArg: 1.138 ± 0.062
1.674ArgSer: 1.674 ± 0.087
1.475ArgThr: 1.475 ± 0.075
1.787ArgVal: 1.787 ± 0.086
0.239ArgTrp: 0.239 ± 0.027
1.384ArgTyr: 1.384 ± 0.08
0.0ArgXaa: 0.0 ± 0.0
Ser
2.932SerAla: 2.932 ± 0.106
0.504SerCys: 0.504 ± 0.042
3.552SerAsp: 3.552 ± 0.124
5.096SerGlu: 5.096 ± 0.139
3.925SerPhe: 3.925 ± 0.129
3.465SerGly: 3.465 ± 0.134
0.808SerHis: 0.808 ± 0.05
6.629SerIle: 6.629 ± 0.186
7.183SerLys: 7.183 ± 0.19
7.314SerLeu: 7.314 ± 0.189
1.004SerMet: 1.004 ± 0.057
5.639SerAsn: 5.639 ± 0.187
1.388SerPro: 1.388 ± 0.069
2.193SerGln: 2.193 ± 0.103
1.997SerArg: 1.997 ± 0.094
5.201SerSer: 5.201 ± 0.15
3.733SerThr: 3.733 ± 0.124
3.787SerVal: 3.787 ± 0.114
0.66SerTrp: 0.66 ± 0.048
3.128SerTyr: 3.128 ± 0.126
0.0SerXaa: 0.0 ± 0.0
Thr
1.982ThrAla: 1.982 ± 0.091
0.279ThrCys: 0.279 ± 0.034
2.49ThrAsp: 2.49 ± 0.091
3.088ThrGlu: 3.088 ± 0.1
2.802ThrPhe: 2.802 ± 0.104
2.428ThrGly: 2.428 ± 0.121
0.812ThrHis: 0.812 ± 0.048
5.078ThrIle: 5.078 ± 0.137
5.291ThrLys: 5.291 ± 0.144
5.088ThrLeu: 5.088 ± 0.138
0.649ThrMet: 0.649 ± 0.052
4.226ThrAsn: 4.226 ± 0.178
1.66ThrPro: 1.66 ± 0.093
1.653ThrGln: 1.653 ± 0.087
1.584ThrArg: 1.584 ± 0.079
3.432ThrSer: 3.432 ± 0.131
3.2ThrThr: 3.2 ± 0.129
2.722ThrVal: 2.722 ± 0.111
0.515ThrTrp: 0.515 ± 0.041
1.99ThrTyr: 1.99 ± 0.098
0.0ThrXaa: 0.0 ± 0.0
Val
2.838ValAla: 2.838 ± 0.13
0.497ValCys: 0.497 ± 0.047
3.494ValAsp: 3.494 ± 0.136
4.219ValGlu: 4.219 ± 0.142
2.925ValPhe: 2.925 ± 0.098
2.878ValGly: 2.878 ± 0.119
0.776ValHis: 0.776 ± 0.063
5.117ValIle: 5.117 ± 0.156
5.324ValLys: 5.324 ± 0.159
5.222ValLeu: 5.222 ± 0.145
0.964ValMet: 0.964 ± 0.062
4.005ValAsn: 4.005 ± 0.111
1.453ValPro: 1.453 ± 0.082
1.493ValGln: 1.493 ± 0.077
1.493ValArg: 1.493 ± 0.086
4.215ValSer: 4.215 ± 0.131
2.49ValThr: 2.49 ± 0.11
3.671ValVal: 3.671 ± 0.147
0.457ValTrp: 0.457 ± 0.045
2.16ValTyr: 2.16 ± 0.105
0.0ValXaa: 0.0 ± 0.0
Trp
0.42TrpAla: 0.42 ± 0.04
0.033TrpCys: 0.033 ± 0.012
0.439TrpAsp: 0.439 ± 0.042
0.645TrpGlu: 0.645 ± 0.053
0.526TrpPhe: 0.526 ± 0.042
0.348TrpGly: 0.348 ± 0.036
0.076TrpHis: 0.076 ± 0.017
1.047TrpIle: 1.047 ± 0.066
0.747TrpLys: 0.747 ± 0.054
0.823TrpLeu: 0.823 ± 0.056
0.21TrpMet: 0.21 ± 0.028
0.826TrpAsn: 0.826 ± 0.058
0.217TrpPro: 0.217 ± 0.028
0.17TrpGln: 0.17 ± 0.026
0.286TrpArg: 0.286 ± 0.029
0.435TrpSer: 0.435 ± 0.038
0.569TrpThr: 0.569 ± 0.053
0.587TrpVal: 0.587 ± 0.047
0.094TrpTrp: 0.094 ± 0.017
0.428TrpTyr: 0.428 ± 0.041
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.928TyrAla: 1.928 ± 0.085
0.323TyrCys: 0.323 ± 0.036
2.831TyrAsp: 2.831 ± 0.109
3.052TyrGlu: 3.052 ± 0.114
2.617TyrPhe: 2.617 ± 0.135
1.99TyrGly: 1.99 ± 0.089
0.562TyrHis: 0.562 ± 0.046
3.693TyrIle: 3.693 ± 0.106
4.454TyrLys: 4.454 ± 0.153
4.443TyrLeu: 4.443 ± 0.144
0.681TyrMet: 0.681 ± 0.044
3.313TyrAsn: 3.313 ± 0.14
1.163TyrPro: 1.163 ± 0.065
1.254TyrGln: 1.254 ± 0.07
1.392TyrArg: 1.392 ± 0.077
3.294TyrSer: 3.294 ± 0.139
1.783TyrThr: 1.783 ± 0.075
2.272TyrVal: 2.272 ± 0.099
0.446TyrTrp: 0.446 ± 0.04
1.812TyrTyr: 1.812 ± 0.095
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.004XaaAsn: 0.004 ± 0.004
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 803 proteins (275923 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski