Amino acid dipepetide frequency for Wuhan House Fly Virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.253AlaAla: 2.253 ± 0.67
1.502AlaCys: 1.502 ± 0.56
3.756AlaAsp: 3.756 ± 1.484
3.505AlaGlu: 3.505 ± 0.868
2.504AlaPhe: 2.504 ± 1.208
2.003AlaGly: 2.003 ± 0.714
1.502AlaHis: 1.502 ± 0.918
4.757AlaIle: 4.757 ± 1.532
3.255AlaLys: 3.255 ± 0.792
4.256AlaLeu: 4.256 ± 1.296
0.751AlaMet: 0.751 ± 0.378
2.504AlaAsn: 2.504 ± 0.921
2.003AlaPro: 2.003 ± 0.595
1.502AlaGln: 1.502 ± 0.67
3.005AlaArg: 3.005 ± 1.525
5.759AlaSer: 5.759 ± 0.754
3.756AlaThr: 3.756 ± 1.258
2.754AlaVal: 2.754 ± 0.733
0.501AlaTrp: 0.501 ± 0.651
1.753AlaTyr: 1.753 ± 0.71
0.0AlaXaa: 0.0 ± 0.0
Cys
0.501CysAla: 0.501 ± 0.329
0.25CysCys: 0.25 ± 0.367
0.25CysAsp: 0.25 ± 0.143
0.751CysGlu: 0.751 ± 0.354
0.25CysPhe: 0.25 ± 0.143
0.25CysGly: 0.25 ± 0.326
0.751CysHis: 0.751 ± 0.363
0.751CysIle: 0.751 ± 0.303
1.002CysLys: 1.002 ± 0.376
1.753CysLeu: 1.753 ± 0.803
0.0CysMet: 0.0 ± 0.0
0.751CysAsn: 0.751 ± 0.413
0.501CysPro: 0.501 ± 0.429
0.751CysGln: 0.751 ± 0.363
0.751CysArg: 0.751 ± 0.544
1.753CysSer: 1.753 ± 0.418
2.003CysThr: 2.003 ± 0.659
1.502CysVal: 1.502 ± 0.709
0.501CysTrp: 0.501 ± 0.286
0.501CysTyr: 0.501 ± 0.455
0.0CysXaa: 0.0 ± 0.0
Asp
4.006AspAla: 4.006 ± 1.119
1.252AspCys: 1.252 ± 0.602
3.255AspAsp: 3.255 ± 0.868
3.756AspGlu: 3.756 ± 1.112
1.502AspPhe: 1.502 ± 0.837
3.005AspGly: 3.005 ± 0.716
1.502AspHis: 1.502 ± 0.509
4.507AspIle: 4.507 ± 0.726
3.756AspLys: 3.756 ± 1.297
5.008AspLeu: 5.008 ± 0.865
2.253AspMet: 2.253 ± 0.772
2.003AspAsn: 2.003 ± 0.584
4.256AspPro: 4.256 ± 0.713
2.754AspGln: 2.754 ± 0.471
2.253AspArg: 2.253 ± 0.785
3.005AspSer: 3.005 ± 1.47
2.253AspThr: 2.253 ± 0.845
3.255AspVal: 3.255 ± 1.008
1.252AspTrp: 1.252 ± 0.714
1.753AspTyr: 1.753 ± 0.565
0.0AspXaa: 0.0 ± 0.0
Glu
1.502GluAla: 1.502 ± 0.674
1.002GluCys: 1.002 ± 0.346
2.504GluAsp: 2.504 ± 0.48
3.005GluGlu: 3.005 ± 1.377
4.006GluPhe: 4.006 ± 0.521
3.255GluGly: 3.255 ± 0.846
1.002GluHis: 1.002 ± 0.393
4.507GluIle: 4.507 ± 1.47
3.255GluLys: 3.255 ± 0.51
6.009GluLeu: 6.009 ± 1.069
2.003GluMet: 2.003 ± 0.533
2.754GluAsn: 2.754 ± 0.79
2.003GluPro: 2.003 ± 0.888
1.753GluGln: 1.753 ± 0.346
1.753GluArg: 1.753 ± 0.603
3.255GluSer: 3.255 ± 0.553
2.754GluThr: 2.754 ± 1.246
3.255GluVal: 3.255 ± 0.844
0.751GluTrp: 0.751 ± 0.513
3.005GluTyr: 3.005 ± 0.865
0.0GluXaa: 0.0 ± 0.0
Phe
2.003PheAla: 2.003 ± 0.704
0.501PheCys: 0.501 ± 0.429
2.754PheAsp: 2.754 ± 0.798
2.003PheGlu: 2.003 ± 0.395
1.753PhePhe: 1.753 ± 0.803
2.003PheGly: 2.003 ± 0.723
1.502PheHis: 1.502 ± 0.537
3.255PheIle: 3.255 ± 0.879
2.504PheLys: 2.504 ± 0.8
4.757PheLeu: 4.757 ± 2.282
0.501PheMet: 0.501 ± 0.264
3.255PheAsn: 3.255 ± 1.093
3.005PhePro: 3.005 ± 1.044
2.754PheGln: 2.754 ± 0.674
2.754PheArg: 2.754 ± 0.767
3.255PheSer: 3.255 ± 0.628
2.003PheThr: 2.003 ± 0.986
1.753PheVal: 1.753 ± 0.394
0.501PheTrp: 0.501 ± 0.306
1.753PheTyr: 1.753 ± 1.096
0.0PheXaa: 0.0 ± 0.0
Gly
1.502GlyAla: 1.502 ± 0.345
0.501GlyCys: 0.501 ± 0.331
3.756GlyAsp: 3.756 ± 0.69
2.504GlyGlu: 2.504 ± 0.667
2.504GlyPhe: 2.504 ± 0.798
2.003GlyGly: 2.003 ± 1.143
1.252GlyHis: 1.252 ± 0.382
4.256GlyIle: 4.256 ± 1.476
1.753GlyLys: 1.753 ± 0.677
6.51GlyLeu: 6.51 ± 2.178
1.002GlyMet: 1.002 ± 0.437
1.753GlyAsn: 1.753 ± 0.46
2.003GlyPro: 2.003 ± 0.481
2.253GlyGln: 2.253 ± 0.744
2.754GlyArg: 2.754 ± 0.975
4.757GlySer: 4.757 ± 1.146
3.505GlyThr: 3.505 ± 0.744
3.005GlyVal: 3.005 ± 1.282
0.751GlyTrp: 0.751 ± 0.303
0.501GlyTyr: 0.501 ± 0.306
0.0GlyXaa: 0.0 ± 0.0
His
2.003HisAla: 2.003 ± 0.626
0.25HisCys: 0.25 ± 0.143
1.502HisAsp: 1.502 ± 0.574
1.252HisGlu: 1.252 ± 0.641
1.252HisPhe: 1.252 ± 0.539
0.25HisGly: 0.25 ± 0.143
0.501HisHis: 0.501 ± 0.464
2.504HisIle: 2.504 ± 0.87
1.002HisLys: 1.002 ± 0.346
2.754HisLeu: 2.754 ± 0.546
0.25HisMet: 0.25 ± 0.143
2.003HisAsn: 2.003 ± 0.612
2.003HisPro: 2.003 ± 1.104
0.501HisGln: 0.501 ± 0.286
1.502HisArg: 1.502 ± 0.442
2.504HisSer: 2.504 ± 1.079
2.003HisThr: 2.003 ± 0.446
1.502HisVal: 1.502 ± 0.948
0.25HisTrp: 0.25 ± 0.143
2.253HisTyr: 2.253 ± 0.781
0.0HisXaa: 0.0 ± 0.0
Ile
4.006IleAla: 4.006 ± 1.255
1.002IleCys: 1.002 ± 0.348
4.507IleAsp: 4.507 ± 1.293
4.757IleGlu: 4.757 ± 0.839
3.505IlePhe: 3.505 ± 0.886
4.757IleGly: 4.757 ± 1.264
3.255IleHis: 3.255 ± 1.132
8.262IleIle: 8.262 ± 1.864
6.51IleLys: 6.51 ± 1.196
6.259IleLeu: 6.259 ± 0.723
1.002IleMet: 1.002 ± 0.429
3.505IleAsn: 3.505 ± 0.93
3.505IlePro: 3.505 ± 0.71
3.756IleGln: 3.756 ± 0.572
3.005IleArg: 3.005 ± 0.738
6.51IleSer: 6.51 ± 0.724
4.256IleThr: 4.256 ± 1.686
2.754IleVal: 2.754 ± 0.347
2.003IleTrp: 2.003 ± 1.301
2.253IleTyr: 2.253 ± 0.789
0.0IleXaa: 0.0 ± 0.0
Lys
1.753LysAla: 1.753 ± 0.916
1.252LysCys: 1.252 ± 0.508
2.754LysAsp: 2.754 ± 0.694
2.504LysGlu: 2.504 ± 0.84
3.005LysPhe: 3.005 ± 0.942
3.005LysGly: 3.005 ± 1.065
0.25LysHis: 0.25 ± 0.143
3.756LysIle: 3.756 ± 0.799
5.508LysLys: 5.508 ± 1.963
5.008LysLeu: 5.008 ± 1.195
1.753LysMet: 1.753 ± 0.603
2.754LysAsn: 2.754 ± 0.665
3.505LysPro: 3.505 ± 1.599
1.753LysGln: 1.753 ± 1.283
3.255LysArg: 3.255 ± 1.4
5.008LysSer: 5.008 ± 1.255
5.008LysThr: 5.008 ± 0.828
3.005LysVal: 3.005 ± 0.668
1.753LysTrp: 1.753 ± 0.697
2.754LysTyr: 2.754 ± 1.038
0.0LysXaa: 0.0 ± 0.0
Leu
5.508LeuAla: 5.508 ± 1.183
1.753LeuCys: 1.753 ± 0.604
5.759LeuAsp: 5.759 ± 1.567
6.259LeuGlu: 6.259 ± 1.42
4.507LeuPhe: 4.507 ± 1.185
4.757LeuGly: 4.757 ± 1.095
2.754LeuHis: 2.754 ± 0.793
8.262LeuIle: 8.262 ± 1.253
5.258LeuLys: 5.258 ± 1.071
9.514LeuLeu: 9.514 ± 0.965
1.753LeuMet: 1.753 ± 0.401
4.507LeuAsn: 4.507 ± 1.146
2.253LeuPro: 2.253 ± 0.715
2.754LeuGln: 2.754 ± 1.034
5.759LeuArg: 5.759 ± 0.985
11.017LeuSer: 11.017 ± 0.783
7.762LeuThr: 7.762 ± 2.036
4.757LeuVal: 4.757 ± 0.869
0.751LeuTrp: 0.751 ± 0.513
5.258LeuTyr: 5.258 ± 0.757
0.0LeuXaa: 0.0 ± 0.0
Met
1.002MetAla: 1.002 ± 0.427
0.25MetCys: 0.25 ± 0.143
1.502MetAsp: 1.502 ± 0.778
1.252MetGlu: 1.252 ± 0.388
1.753MetPhe: 1.753 ± 0.601
1.252MetGly: 1.252 ± 0.39
0.501MetHis: 0.501 ± 0.264
1.252MetIle: 1.252 ± 0.714
2.253MetLys: 2.253 ± 1.231
1.502MetLeu: 1.502 ± 0.52
0.501MetMet: 0.501 ± 0.286
0.501MetAsn: 0.501 ± 0.286
1.002MetPro: 1.002 ± 0.45
0.25MetGln: 0.25 ± 0.143
0.25MetArg: 0.25 ± 0.143
1.753MetSer: 1.753 ± 0.76
1.252MetThr: 1.252 ± 0.389
1.002MetVal: 1.002 ± 0.356
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.505AsnAla: 3.505 ± 1.321
0.0AsnCys: 0.0 ± 0.0
2.003AsnAsp: 2.003 ± 0.481
2.253AsnGlu: 2.253 ± 0.816
1.502AsnPhe: 1.502 ± 0.455
2.504AsnGly: 2.504 ± 0.682
2.003AsnHis: 2.003 ± 0.747
4.256AsnIle: 4.256 ± 0.455
2.504AsnLys: 2.504 ± 1.095
8.262AsnLeu: 8.262 ± 0.87
0.501AsnMet: 0.501 ± 0.306
2.003AsnAsn: 2.003 ± 0.936
4.757AsnPro: 4.757 ± 0.922
2.504AsnGln: 2.504 ± 0.624
2.253AsnArg: 2.253 ± 0.857
3.505AsnSer: 3.505 ± 1.191
2.754AsnThr: 2.754 ± 1.019
2.504AsnVal: 2.504 ± 0.916
1.002AsnTrp: 1.002 ± 0.643
2.003AsnTyr: 2.003 ± 0.481
0.0AsnXaa: 0.0 ± 0.0
Pro
4.256ProAla: 4.256 ± 1.397
0.751ProCys: 0.751 ± 0.466
4.256ProAsp: 4.256 ± 0.816
2.003ProGlu: 2.003 ± 0.832
1.753ProPhe: 1.753 ± 0.671
1.502ProGly: 1.502 ± 0.807
2.253ProHis: 2.253 ± 0.604
3.005ProIle: 3.005 ± 0.979
1.502ProLys: 1.502 ± 0.515
4.256ProLeu: 4.256 ± 0.833
0.25ProMet: 0.25 ± 0.326
2.253ProAsn: 2.253 ± 0.775
2.253ProPro: 2.253 ± 1.101
1.252ProGln: 1.252 ± 0.375
2.754ProArg: 2.754 ± 0.719
6.009ProSer: 6.009 ± 1.532
2.253ProThr: 2.253 ± 1.098
3.505ProVal: 3.505 ± 1.016
1.252ProTrp: 1.252 ± 0.389
1.753ProTyr: 1.753 ± 0.884
0.0ProXaa: 0.0 ± 0.0
Gln
1.252GlnAla: 1.252 ± 0.643
0.501GlnCys: 0.501 ± 0.429
1.002GlnAsp: 1.002 ± 0.356
2.253GlnGlu: 2.253 ± 0.629
1.252GlnPhe: 1.252 ± 0.714
2.504GlnGly: 2.504 ± 0.854
1.252GlnHis: 1.252 ± 0.375
4.006GlnIle: 4.006 ± 0.447
2.253GlnLys: 2.253 ± 0.53
3.505GlnLeu: 3.505 ± 0.478
0.501GlnMet: 0.501 ± 0.355
2.754GlnAsn: 2.754 ± 0.636
2.003GlnPro: 2.003 ± 0.431
1.502GlnGln: 1.502 ± 0.662
1.502GlnArg: 1.502 ± 0.529
2.504GlnSer: 2.504 ± 0.623
2.253GlnThr: 2.253 ± 0.585
2.754GlnVal: 2.754 ± 1.248
0.25GlnTrp: 0.25 ± 0.143
0.751GlnTyr: 0.751 ± 0.344
0.0GlnXaa: 0.0 ± 0.0
Arg
3.005ArgAla: 3.005 ± 0.651
1.252ArgCys: 1.252 ± 0.523
1.502ArgAsp: 1.502 ± 0.755
3.005ArgGlu: 3.005 ± 0.897
2.754ArgPhe: 2.754 ± 0.377
2.003ArgGly: 2.003 ± 0.875
1.252ArgHis: 1.252 ± 0.539
4.006ArgIle: 4.006 ± 0.678
2.504ArgLys: 2.504 ± 1.388
4.757ArgLeu: 4.757 ± 0.777
0.501ArgMet: 0.501 ± 0.306
3.005ArgAsn: 3.005 ± 0.941
2.504ArgPro: 2.504 ± 0.906
2.003ArgGln: 2.003 ± 0.626
2.504ArgArg: 2.504 ± 1.092
3.005ArgSer: 3.005 ± 0.908
3.005ArgThr: 3.005 ± 0.934
1.753ArgVal: 1.753 ± 0.942
1.502ArgTrp: 1.502 ± 0.673
2.003ArgTyr: 2.003 ± 1.357
0.0ArgXaa: 0.0 ± 0.0
Ser
6.259SerAla: 6.259 ± 1.087
1.002SerCys: 1.002 ± 0.572
5.508SerAsp: 5.508 ± 1.255
4.256SerGlu: 4.256 ± 1.099
3.005SerPhe: 3.005 ± 0.716
3.756SerGly: 3.756 ± 0.679
2.253SerHis: 2.253 ± 0.95
6.51SerIle: 6.51 ± 1.782
5.508SerLys: 5.508 ± 0.855
10.015SerLeu: 10.015 ± 1.849
2.003SerMet: 2.003 ± 0.696
4.256SerAsn: 4.256 ± 1.739
2.253SerPro: 2.253 ± 0.748
3.005SerGln: 3.005 ± 0.955
4.507SerArg: 4.507 ± 0.698
6.76SerSer: 6.76 ± 1.12
6.009SerThr: 6.009 ± 1.636
4.256SerVal: 4.256 ± 1.02
1.753SerTrp: 1.753 ± 0.576
3.005SerTyr: 3.005 ± 0.655
0.0SerXaa: 0.0 ± 0.0
Thr
3.505ThrAla: 3.505 ± 1.646
0.751ThrCys: 0.751 ± 0.303
3.505ThrAsp: 3.505 ± 1.754
3.005ThrGlu: 3.005 ± 0.698
2.504ThrPhe: 2.504 ± 0.569
2.754ThrGly: 2.754 ± 0.908
1.252ThrHis: 1.252 ± 0.841
4.757ThrIle: 4.757 ± 1.389
3.756ThrLys: 3.756 ± 0.905
6.009ThrLeu: 6.009 ± 1.744
1.252ThrMet: 1.252 ± 0.549
3.255ThrAsn: 3.255 ± 0.616
4.006ThrPro: 4.006 ± 1.68
2.253ThrGln: 2.253 ± 0.624
3.255ThrArg: 3.255 ± 0.491
6.009ThrSer: 6.009 ± 2.036
7.762ThrThr: 7.762 ± 2.19
3.255ThrVal: 3.255 ± 0.881
0.751ThrTrp: 0.751 ± 0.349
2.003ThrTyr: 2.003 ± 0.682
0.0ThrXaa: 0.0 ± 0.0
Val
2.253ValAla: 2.253 ± 0.923
0.751ValCys: 0.751 ± 0.354
3.756ValAsp: 3.756 ± 1.147
3.005ValGlu: 3.005 ± 0.631
2.003ValPhe: 2.003 ± 0.438
4.006ValGly: 4.006 ± 0.966
1.502ValHis: 1.502 ± 0.942
3.505ValIle: 3.505 ± 0.911
1.002ValLys: 1.002 ± 0.358
5.258ValLeu: 5.258 ± 1.26
0.751ValMet: 0.751 ± 0.344
4.256ValAsn: 4.256 ± 0.596
2.253ValPro: 2.253 ± 0.897
1.753ValGln: 1.753 ± 0.371
2.253ValArg: 2.253 ± 0.778
4.757ValSer: 4.757 ± 2.106
2.253ValThr: 2.253 ± 0.928
3.005ValVal: 3.005 ± 1.514
0.751ValTrp: 0.751 ± 0.521
1.753ValTyr: 1.753 ± 0.346
0.0ValXaa: 0.0 ± 0.0
Trp
0.751TrpAla: 0.751 ± 0.616
0.25TrpCys: 0.25 ± 0.326
1.002TrpAsp: 1.002 ± 0.427
1.002TrpGlu: 1.002 ± 0.869
1.252TrpPhe: 1.252 ± 0.389
1.502TrpGly: 1.502 ± 0.857
0.751TrpHis: 0.751 ± 0.544
1.252TrpIle: 1.252 ± 0.641
1.502TrpLys: 1.502 ± 1.042
0.751TrpLeu: 0.751 ± 0.544
0.501TrpMet: 0.501 ± 0.464
1.502TrpAsn: 1.502 ± 0.606
0.501TrpPro: 0.501 ± 0.286
0.25TrpGln: 0.25 ± 0.143
0.25TrpArg: 0.25 ± 0.367
1.753TrpSer: 1.753 ± 0.565
1.502TrpThr: 1.502 ± 1.034
0.0TrpVal: 0.0 ± 0.0
0.25TrpTrp: 0.25 ± 0.298
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.754TyrAla: 2.754 ± 1.012
0.751TyrCys: 0.751 ± 0.344
2.003TyrAsp: 2.003 ± 0.781
1.002TyrGlu: 1.002 ± 0.393
2.003TyrPhe: 2.003 ± 0.449
1.753TyrGly: 1.753 ± 0.501
0.751TyrHis: 0.751 ± 0.429
2.003TyrIle: 2.003 ± 0.431
2.754TyrLys: 2.754 ± 0.781
4.757TyrLeu: 4.757 ± 0.801
0.751TyrMet: 0.751 ± 0.429
3.005TyrAsn: 3.005 ± 0.987
2.504TyrPro: 2.504 ± 0.608
1.252TyrGln: 1.252 ± 0.634
1.502TyrArg: 1.502 ± 0.903
3.005TyrSer: 3.005 ± 1.291
1.252TyrThr: 1.252 ± 0.748
1.252TyrVal: 1.252 ± 0.545
0.0TyrTrp: 0.0 ± 0.0
1.002TyrTyr: 1.002 ± 0.967
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (3995 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski