Amino acid dipepetide frequency for Hubei picorna-like virus 49

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.303AlaAla: 5.303 ± 0.0
1.989AlaCys: 1.989 ± 0.0
4.309AlaAsp: 4.309 ± 0.0
3.315AlaGlu: 3.315 ± 0.0
3.646AlaPhe: 3.646 ± 0.0
6.298AlaGly: 6.298 ± 0.0
1.989AlaHis: 1.989 ± 0.0
5.303AlaIle: 5.303 ± 0.0
1.326AlaLys: 1.326 ± 0.0
5.635AlaLeu: 5.635 ± 0.0
0.663AlaMet: 0.663 ± 0.0
2.32AlaAsn: 2.32 ± 0.0
3.315AlaPro: 3.315 ± 0.0
0.663AlaGln: 0.663 ± 0.0
2.983AlaArg: 2.983 ± 0.0
5.966AlaSer: 5.966 ± 0.0
4.972AlaThr: 4.972 ± 0.0
4.972AlaVal: 4.972 ± 0.0
0.994AlaTrp: 0.994 ± 0.0
2.32AlaTyr: 2.32 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.657CysAla: 1.657 ± 0.0
0.331CysCys: 0.331 ± 0.0
1.657CysAsp: 1.657 ± 0.0
1.989CysGlu: 1.989 ± 0.0
1.657CysPhe: 1.657 ± 0.0
2.32CysGly: 2.32 ± 0.0
1.326CysHis: 1.326 ± 0.0
0.663CysIle: 0.663 ± 0.0
0.331CysLys: 0.331 ± 0.0
1.326CysLeu: 1.326 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.657CysAsn: 1.657 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.663CysGln: 0.663 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.989CysSer: 1.989 ± 0.0
0.994CysThr: 0.994 ± 0.0
1.657CysVal: 1.657 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.994CysTyr: 0.994 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.646AspAla: 3.646 ± 0.0
0.663AspCys: 0.663 ± 0.0
5.966AspAsp: 5.966 ± 0.0
2.983AspGlu: 2.983 ± 0.0
2.983AspPhe: 2.983 ± 0.0
2.983AspGly: 2.983 ± 0.0
1.657AspHis: 1.657 ± 0.0
3.646AspIle: 3.646 ± 0.0
1.989AspLys: 1.989 ± 0.0
5.635AspLeu: 5.635 ± 0.0
0.663AspMet: 0.663 ± 0.0
1.989AspAsn: 1.989 ± 0.0
2.983AspPro: 2.983 ± 0.0
0.994AspGln: 0.994 ± 0.0
2.652AspArg: 2.652 ± 0.0
5.966AspSer: 5.966 ± 0.0
4.972AspThr: 4.972 ± 0.0
3.646AspVal: 3.646 ± 0.0
0.331AspTrp: 0.331 ± 0.0
0.994AspTyr: 0.994 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
4.64GluAla: 4.64 ± 0.0
0.994GluCys: 0.994 ± 0.0
2.32GluAsp: 2.32 ± 0.0
3.315GluGlu: 3.315 ± 0.0
1.657GluPhe: 1.657 ± 0.0
1.657GluGly: 1.657 ± 0.0
1.326GluHis: 1.326 ± 0.0
2.983GluIle: 2.983 ± 0.0
1.989GluLys: 1.989 ± 0.0
5.966GluLeu: 5.966 ± 0.0
1.989GluMet: 1.989 ± 0.0
1.326GluAsn: 1.326 ± 0.0
2.32GluPro: 2.32 ± 0.0
3.315GluGln: 3.315 ± 0.0
2.983GluArg: 2.983 ± 0.0
1.989GluSer: 1.989 ± 0.0
4.309GluThr: 4.309 ± 0.0
2.652GluVal: 2.652 ± 0.0
0.663GluTrp: 0.663 ± 0.0
1.326GluTyr: 1.326 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
3.646PheAla: 3.646 ± 0.0
1.326PheCys: 1.326 ± 0.0
2.32PheAsp: 2.32 ± 0.0
4.64PheGlu: 4.64 ± 0.0
3.646PhePhe: 3.646 ± 0.0
3.315PheGly: 3.315 ± 0.0
0.331PheHis: 0.331 ± 0.0
3.646PheIle: 3.646 ± 0.0
1.657PheLys: 1.657 ± 0.0
3.977PheLeu: 3.977 ± 0.0
0.663PheMet: 0.663 ± 0.0
2.32PheAsn: 2.32 ± 0.0
2.652PhePro: 2.652 ± 0.0
2.652PheGln: 2.652 ± 0.0
3.315PheArg: 3.315 ± 0.0
4.309PheSer: 4.309 ± 0.0
2.983PheThr: 2.983 ± 0.0
5.635PheVal: 5.635 ± 0.0
0.663PheTrp: 0.663 ± 0.0
1.989PheTyr: 1.989 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.309GlyAla: 4.309 ± 0.0
0.663GlyCys: 0.663 ± 0.0
4.972GlyAsp: 4.972 ± 0.0
2.32GlyGlu: 2.32 ± 0.0
3.977GlyPhe: 3.977 ± 0.0
2.32GlyGly: 2.32 ± 0.0
1.326GlyHis: 1.326 ± 0.0
3.977GlyIle: 3.977 ± 0.0
2.652GlyLys: 2.652 ± 0.0
4.972GlyLeu: 4.972 ± 0.0
0.331GlyMet: 0.331 ± 0.0
2.652GlyAsn: 2.652 ± 0.0
0.663GlyPro: 0.663 ± 0.0
1.989GlyGln: 1.989 ± 0.0
3.646GlyArg: 3.646 ± 0.0
4.64GlySer: 4.64 ± 0.0
2.983GlyThr: 2.983 ± 0.0
5.966GlyVal: 5.966 ± 0.0
0.0GlyTrp: 0.0 ± 0.0
2.32GlyTyr: 2.32 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.32HisAla: 2.32 ± 0.0
0.994HisCys: 0.994 ± 0.0
1.326HisAsp: 1.326 ± 0.0
1.657HisGlu: 1.657 ± 0.0
1.989HisPhe: 1.989 ± 0.0
1.326HisGly: 1.326 ± 0.0
1.657HisHis: 1.657 ± 0.0
2.652HisIle: 2.652 ± 0.0
1.657HisLys: 1.657 ± 0.0
2.652HisLeu: 2.652 ± 0.0
0.663HisMet: 0.663 ± 0.0
0.663HisAsn: 0.663 ± 0.0
1.657HisPro: 1.657 ± 0.0
1.657HisGln: 1.657 ± 0.0
1.326HisArg: 1.326 ± 0.0
1.657HisSer: 1.657 ± 0.0
1.657HisThr: 1.657 ± 0.0
1.326HisVal: 1.326 ± 0.0
0.331HisTrp: 0.331 ± 0.0
1.657HisTyr: 1.657 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.309IleAla: 4.309 ± 0.0
1.989IleCys: 1.989 ± 0.0
2.652IleAsp: 2.652 ± 0.0
3.977IleGlu: 3.977 ± 0.0
3.315IlePhe: 3.315 ± 0.0
3.315IleGly: 3.315 ± 0.0
1.326IleHis: 1.326 ± 0.0
5.635IleIle: 5.635 ± 0.0
3.977IleLys: 3.977 ± 0.0
3.315IleLeu: 3.315 ± 0.0
1.657IleMet: 1.657 ± 0.0
2.32IleAsn: 2.32 ± 0.0
4.972IlePro: 4.972 ± 0.0
2.32IleGln: 2.32 ± 0.0
4.64IleArg: 4.64 ± 0.0
5.303IleSer: 5.303 ± 0.0
3.977IleThr: 3.977 ± 0.0
4.64IleVal: 4.64 ± 0.0
0.663IleTrp: 0.663 ± 0.0
2.32IleTyr: 2.32 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
1.657LysAla: 1.657 ± 0.0
0.331LysCys: 0.331 ± 0.0
2.32LysAsp: 2.32 ± 0.0
0.663LysGlu: 0.663 ± 0.0
2.983LysPhe: 2.983 ± 0.0
1.989LysGly: 1.989 ± 0.0
1.989LysHis: 1.989 ± 0.0
3.315LysIle: 3.315 ± 0.0
0.663LysLys: 0.663 ± 0.0
2.652LysLeu: 2.652 ± 0.0
0.663LysMet: 0.663 ± 0.0
2.32LysAsn: 2.32 ± 0.0
2.32LysPro: 2.32 ± 0.0
2.983LysGln: 2.983 ± 0.0
2.652LysArg: 2.652 ± 0.0
2.983LysSer: 2.983 ± 0.0
2.32LysThr: 2.32 ± 0.0
2.652LysVal: 2.652 ± 0.0
0.663LysTrp: 0.663 ± 0.0
1.657LysTyr: 1.657 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
5.635LeuAla: 5.635 ± 0.0
2.652LeuCys: 2.652 ± 0.0
5.966LeuAsp: 5.966 ± 0.0
1.989LeuGlu: 1.989 ± 0.0
3.977LeuPhe: 3.977 ± 0.0
3.646LeuGly: 3.646 ± 0.0
0.994LeuHis: 0.994 ± 0.0
3.315LeuIle: 3.315 ± 0.0
4.972LeuLys: 4.972 ± 0.0
4.972LeuLeu: 4.972 ± 0.0
1.989LeuMet: 1.989 ± 0.0
3.977LeuAsn: 3.977 ± 0.0
4.64LeuPro: 4.64 ± 0.0
3.646LeuGln: 3.646 ± 0.0
3.315LeuArg: 3.315 ± 0.0
6.629LeuSer: 6.629 ± 0.0
5.966LeuThr: 5.966 ± 0.0
4.64LeuVal: 4.64 ± 0.0
1.326LeuTrp: 1.326 ± 0.0
3.977LeuTyr: 3.977 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
1.326MetAla: 1.326 ± 0.0
0.0MetCys: 0.0 ± 0.0
0.994MetAsp: 0.994 ± 0.0
0.331MetGlu: 0.331 ± 0.0
0.994MetPhe: 0.994 ± 0.0
0.331MetGly: 0.331 ± 0.0
0.994MetHis: 0.994 ± 0.0
0.994MetIle: 0.994 ± 0.0
1.657MetLys: 1.657 ± 0.0
1.989MetLeu: 1.989 ± 0.0
0.0MetMet: 0.0 ± 0.0
1.326MetAsn: 1.326 ± 0.0
1.989MetPro: 1.989 ± 0.0
0.994MetGln: 0.994 ± 0.0
0.331MetArg: 0.331 ± 0.0
1.989MetSer: 1.989 ± 0.0
0.663MetThr: 0.663 ± 0.0
0.994MetVal: 0.994 ± 0.0
0.331MetTrp: 0.331 ± 0.0
1.657MetTyr: 1.657 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
6.298AsnAla: 6.298 ± 0.0
0.331AsnCys: 0.331 ± 0.0
2.32AsnAsp: 2.32 ± 0.0
1.326AsnGlu: 1.326 ± 0.0
1.657AsnPhe: 1.657 ± 0.0
1.657AsnGly: 1.657 ± 0.0
1.657AsnHis: 1.657 ± 0.0
4.64AsnIle: 4.64 ± 0.0
1.657AsnLys: 1.657 ± 0.0
2.983AsnLeu: 2.983 ± 0.0
2.32AsnMet: 2.32 ± 0.0
1.989AsnAsn: 1.989 ± 0.0
1.657AsnPro: 1.657 ± 0.0
1.326AsnGln: 1.326 ± 0.0
1.989AsnArg: 1.989 ± 0.0
2.983AsnSer: 2.983 ± 0.0
2.652AsnThr: 2.652 ± 0.0
3.977AsnVal: 3.977 ± 0.0
0.331AsnTrp: 0.331 ± 0.0
0.331AsnTyr: 0.331 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
2.652ProAla: 2.652 ± 0.0
0.994ProCys: 0.994 ± 0.0
2.983ProAsp: 2.983 ± 0.0
3.646ProGlu: 3.646 ± 0.0
2.983ProPhe: 2.983 ± 0.0
3.315ProGly: 3.315 ± 0.0
1.657ProHis: 1.657 ± 0.0
3.977ProIle: 3.977 ± 0.0
1.989ProLys: 1.989 ± 0.0
2.983ProLeu: 2.983 ± 0.0
1.657ProMet: 1.657 ± 0.0
0.994ProAsn: 0.994 ± 0.0
4.64ProPro: 4.64 ± 0.0
1.989ProGln: 1.989 ± 0.0
0.994ProArg: 0.994 ± 0.0
5.635ProSer: 5.635 ± 0.0
1.989ProThr: 1.989 ± 0.0
4.64ProVal: 4.64 ± 0.0
0.994ProTrp: 0.994 ± 0.0
2.652ProTyr: 2.652 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.989GlnAla: 1.989 ± 0.0
0.994GlnCys: 0.994 ± 0.0
0.994GlnAsp: 0.994 ± 0.0
1.989GlnGlu: 1.989 ± 0.0
3.315GlnPhe: 3.315 ± 0.0
3.315GlnGly: 3.315 ± 0.0
3.315GlnHis: 3.315 ± 0.0
0.994GlnIle: 0.994 ± 0.0
1.657GlnLys: 1.657 ± 0.0
2.652GlnLeu: 2.652 ± 0.0
0.994GlnMet: 0.994 ± 0.0
1.989GlnAsn: 1.989 ± 0.0
1.989GlnPro: 1.989 ± 0.0
1.989GlnGln: 1.989 ± 0.0
1.657GlnArg: 1.657 ± 0.0
2.652GlnSer: 2.652 ± 0.0
1.989GlnThr: 1.989 ± 0.0
3.977GlnVal: 3.977 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
0.663GlnTyr: 0.663 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.315ArgAla: 3.315 ± 0.0
0.994ArgCys: 0.994 ± 0.0
3.315ArgAsp: 3.315 ± 0.0
1.657ArgGlu: 1.657 ± 0.0
3.315ArgPhe: 3.315 ± 0.0
3.646ArgGly: 3.646 ± 0.0
0.994ArgHis: 0.994 ± 0.0
2.32ArgIle: 2.32 ± 0.0
0.663ArgLys: 0.663 ± 0.0
4.309ArgLeu: 4.309 ± 0.0
0.663ArgMet: 0.663 ± 0.0
1.657ArgAsn: 1.657 ± 0.0
1.657ArgPro: 1.657 ± 0.0
2.652ArgGln: 2.652 ± 0.0
3.646ArgArg: 3.646 ± 0.0
3.977ArgSer: 3.977 ± 0.0
2.32ArgThr: 2.32 ± 0.0
6.629ArgVal: 6.629 ± 0.0
0.0ArgTrp: 0.0 ± 0.0
2.652ArgTyr: 2.652 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
5.966SerAla: 5.966 ± 0.0
2.32SerCys: 2.32 ± 0.0
4.309SerAsp: 4.309 ± 0.0
3.977SerGlu: 3.977 ± 0.0
3.646SerPhe: 3.646 ± 0.0
5.635SerGly: 5.635 ± 0.0
1.657SerHis: 1.657 ± 0.0
7.623SerIle: 7.623 ± 0.0
3.977SerLys: 3.977 ± 0.0
6.961SerLeu: 6.961 ± 0.0
1.657SerMet: 1.657 ± 0.0
4.309SerAsn: 4.309 ± 0.0
4.64SerPro: 4.64 ± 0.0
1.989SerGln: 1.989 ± 0.0
2.652SerArg: 2.652 ± 0.0
9.944SerSer: 9.944 ± 0.0
3.977SerThr: 3.977 ± 0.0
5.303SerVal: 5.303 ± 0.0
0.994SerTrp: 0.994 ± 0.0
1.989SerTyr: 1.989 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
2.652ThrAla: 2.652 ± 0.0
0.994ThrCys: 0.994 ± 0.0
2.32ThrAsp: 2.32 ± 0.0
2.32ThrGlu: 2.32 ± 0.0
3.977ThrPhe: 3.977 ± 0.0
2.652ThrGly: 2.652 ± 0.0
1.989ThrHis: 1.989 ± 0.0
5.635ThrIle: 5.635 ± 0.0
1.989ThrLys: 1.989 ± 0.0
5.635ThrLeu: 5.635 ± 0.0
0.994ThrMet: 0.994 ± 0.0
2.983ThrAsn: 2.983 ± 0.0
4.972ThrPro: 4.972 ± 0.0
2.652ThrGln: 2.652 ± 0.0
4.309ThrArg: 4.309 ± 0.0
4.64ThrSer: 4.64 ± 0.0
5.303ThrThr: 5.303 ± 0.0
3.315ThrVal: 3.315 ± 0.0
0.663ThrTrp: 0.663 ± 0.0
2.983ThrTyr: 2.983 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
4.309ValAla: 4.309 ± 0.0
1.657ValCys: 1.657 ± 0.0
4.972ValAsp: 4.972 ± 0.0
5.303ValGlu: 5.303 ± 0.0
4.309ValPhe: 4.309 ± 0.0
4.309ValGly: 4.309 ± 0.0
2.983ValHis: 2.983 ± 0.0
3.315ValIle: 3.315 ± 0.0
2.652ValLys: 2.652 ± 0.0
6.961ValLeu: 6.961 ± 0.0
0.663ValMet: 0.663 ± 0.0
3.646ValAsn: 3.646 ± 0.0
2.983ValPro: 2.983 ± 0.0
1.989ValGln: 1.989 ± 0.0
3.646ValArg: 3.646 ± 0.0
7.292ValSer: 7.292 ± 0.0
6.298ValThr: 6.298 ± 0.0
4.309ValVal: 4.309 ± 0.0
0.994ValTrp: 0.994 ± 0.0
2.652ValTyr: 2.652 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.663TrpAla: 0.663 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.331TrpAsp: 0.331 ± 0.0
0.663TrpGlu: 0.663 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.331TrpHis: 0.331 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.331TrpLys: 0.331 ± 0.0
1.326TrpLeu: 1.326 ± 0.0
0.331TrpMet: 0.331 ± 0.0
0.663TrpAsn: 0.663 ± 0.0
0.663TrpPro: 0.663 ± 0.0
0.663TrpGln: 0.663 ± 0.0
1.326TrpArg: 1.326 ± 0.0
1.326TrpSer: 1.326 ± 0.0
0.663TrpThr: 0.663 ± 0.0
0.663TrpVal: 0.663 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.331TrpTyr: 0.331 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.989TyrAla: 1.989 ± 0.0
0.994TyrCys: 0.994 ± 0.0
1.326TyrAsp: 1.326 ± 0.0
1.657TyrGlu: 1.657 ± 0.0
1.657TyrPhe: 1.657 ± 0.0
2.652TyrGly: 2.652 ± 0.0
1.326TyrHis: 1.326 ± 0.0
1.989TyrIle: 1.989 ± 0.0
1.989TyrLys: 1.989 ± 0.0
1.326TyrLeu: 1.326 ± 0.0
0.994TyrMet: 0.994 ± 0.0
2.983TyrAsn: 2.983 ± 0.0
2.652TyrPro: 2.652 ± 0.0
1.989TyrGln: 1.989 ± 0.0
2.32TyrArg: 2.32 ± 0.0
1.657TyrSer: 1.657 ± 0.0
1.989TyrThr: 1.989 ± 0.0
3.646TyrVal: 3.646 ± 0.0
0.331TyrTrp: 0.331 ± 0.0
1.326TyrTyr: 1.326 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (3018 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski