Amino acid dipepetide frequency for Tortoise microvirus 49

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.914AlaAla: 6.914 ± 2.309
0.0AlaCys: 0.0 ± 0.0
1.886AlaAsp: 1.886 ± 1.25
2.514AlaGlu: 2.514 ± 1.896
3.143AlaPhe: 3.143 ± 0.66
6.285AlaGly: 6.285 ± 3.487
1.886AlaHis: 1.886 ± 0.924
1.886AlaIle: 1.886 ± 1.167
1.257AlaLys: 1.257 ± 1.079
6.285AlaLeu: 6.285 ± 1.443
3.143AlaMet: 3.143 ± 1.31
5.028AlaAsn: 5.028 ± 2.439
2.514AlaPro: 2.514 ± 0.897
1.257AlaGln: 1.257 ± 0.899
6.285AlaArg: 6.285 ± 3.371
7.542AlaSer: 7.542 ± 1.607
1.886AlaThr: 1.886 ± 0.798
5.028AlaVal: 5.028 ± 1.243
1.257AlaTrp: 1.257 ± 0.531
4.4AlaTyr: 4.4 ± 0.676
0.0AlaXaa: 0.0 ± 0.0
Cys
0.629CysAla: 0.629 ± 0.889
0.629CysCys: 0.629 ± 0.743
1.257CysAsp: 1.257 ± 0.928
0.629CysGlu: 0.629 ± 0.54
0.0CysPhe: 0.0 ± 0.0
1.886CysGly: 1.886 ± 1.23
0.629CysHis: 0.629 ± 0.743
0.0CysIle: 0.0 ± 0.0
1.257CysLys: 1.257 ± 0.863
1.886CysLeu: 1.886 ± 1.23
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
1.886CysGln: 1.886 ± 1.317
1.886CysArg: 1.886 ± 1.736
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.629CysVal: 0.629 ± 0.743
0.0CysTrp: 0.0 ± 0.0
1.257CysTyr: 1.257 ± 0.531
0.0CysXaa: 0.0 ± 0.0
Asp
5.028AspAla: 5.028 ± 1.336
0.0AspCys: 0.0 ± 0.0
4.4AspAsp: 4.4 ± 2.394
1.886AspGlu: 1.886 ± 0.829
5.657AspPhe: 5.657 ± 0.509
3.771AspGly: 3.771 ± 1.06
1.886AspHis: 1.886 ± 0.835
3.143AspIle: 3.143 ± 1.74
5.657AspLys: 5.657 ± 2.868
6.914AspLeu: 6.914 ± 2.254
0.0AspMet: 0.0 ± 0.0
1.257AspAsn: 1.257 ± 0.863
0.629AspPro: 0.629 ± 0.426
2.514AspGln: 2.514 ± 1.081
3.771AspArg: 3.771 ± 1.28
3.771AspSer: 3.771 ± 1.584
1.886AspThr: 1.886 ± 1.234
3.143AspVal: 3.143 ± 1.342
0.0AspTrp: 0.0 ± 0.0
3.143AspTyr: 3.143 ± 1.102
0.0AspXaa: 0.0 ± 0.0
Glu
4.4GluAla: 4.4 ± 1.869
1.257GluCys: 1.257 ± 0.928
1.886GluAsp: 1.886 ± 0.798
3.143GluGlu: 3.143 ± 1.464
3.771GluPhe: 3.771 ± 1.435
3.771GluGly: 3.771 ± 1.586
2.514GluHis: 2.514 ± 1.063
1.886GluIle: 1.886 ± 0.994
3.143GluLys: 3.143 ± 2.202
5.028GluLeu: 5.028 ± 1.322
0.0GluMet: 0.0 ± 0.0
4.4GluAsn: 4.4 ± 2.306
0.629GluPro: 0.629 ± 0.561
3.143GluGln: 3.143 ± 0.735
6.285GluArg: 6.285 ± 3.219
1.257GluSer: 1.257 ± 0.521
1.257GluThr: 1.257 ± 0.899
3.771GluVal: 3.771 ± 1.293
0.0GluTrp: 0.0 ± 0.0
3.143GluTyr: 3.143 ± 1.014
0.0GluXaa: 0.0 ± 0.0
Phe
3.143PheAla: 3.143 ± 1.305
0.629PheCys: 0.629 ± 0.889
6.914PheAsp: 6.914 ± 0.897
2.514PheGlu: 2.514 ± 0.986
3.771PhePhe: 3.771 ± 1.428
4.4PheGly: 4.4 ± 1.76
0.629PheHis: 0.629 ± 0.54
3.771PheIle: 3.771 ± 1.594
1.886PheLys: 1.886 ± 1.227
1.886PheLeu: 1.886 ± 0.724
1.257PheMet: 1.257 ± 0.811
2.514PheAsn: 2.514 ± 0.949
1.257PhePro: 1.257 ± 0.531
1.886PheGln: 1.886 ± 0.768
5.657PheArg: 5.657 ± 2.041
0.629PheSer: 0.629 ± 0.426
1.886PheThr: 1.886 ± 0.798
5.028PheVal: 5.028 ± 1.446
1.257PheTrp: 1.257 ± 0.966
4.4PheTyr: 4.4 ± 2.545
0.0PheXaa: 0.0 ± 0.0
Gly
3.143GlyAla: 3.143 ± 1.102
0.0GlyCys: 0.0 ± 0.0
5.028GlyAsp: 5.028 ± 1.647
5.028GlyGlu: 5.028 ± 1.828
1.257GlyPhe: 1.257 ± 0.722
4.4GlyGly: 4.4 ± 1.742
0.0GlyHis: 0.0 ± 0.0
5.657GlyIle: 5.657 ± 2.309
2.514GlyLys: 2.514 ± 1.234
4.4GlyLeu: 4.4 ± 0.847
1.257GlyMet: 1.257 ± 0.886
3.771GlyAsn: 3.771 ± 1.239
1.886GlyPro: 1.886 ± 0.798
1.886GlyGln: 1.886 ± 0.994
1.886GlyArg: 1.886 ± 1.196
5.657GlySer: 5.657 ± 2.646
4.4GlyThr: 4.4 ± 1.825
6.285GlyVal: 6.285 ± 3.531
0.0GlyTrp: 0.0 ± 0.0
2.514GlyTyr: 2.514 ± 1.145
0.0GlyXaa: 0.0 ± 0.0
His
0.629HisAla: 0.629 ± 0.889
0.0HisCys: 0.0 ± 0.0
0.629HisAsp: 0.629 ± 0.54
0.0HisGlu: 0.0 ± 0.0
0.629HisPhe: 0.629 ± 0.426
1.886HisGly: 1.886 ± 0.798
0.0HisHis: 0.0 ± 0.0
0.629HisIle: 0.629 ± 0.743
0.0HisLys: 0.0 ± 0.0
1.886HisLeu: 1.886 ± 1.102
1.886HisMet: 1.886 ± 1.198
1.886HisAsn: 1.886 ± 0.798
1.886HisPro: 1.886 ± 0.983
0.629HisGln: 0.629 ± 0.889
1.257HisArg: 1.257 ± 0.852
0.0HisSer: 0.0 ± 0.0
1.886HisThr: 1.886 ± 1.402
0.629HisVal: 0.629 ± 0.426
0.629HisTrp: 0.629 ± 0.54
0.629HisTyr: 0.629 ± 0.54
0.0HisXaa: 0.0 ± 0.0
Ile
3.143IleAla: 3.143 ± 1.24
1.257IleCys: 1.257 ± 0.928
3.143IleAsp: 3.143 ± 1.884
1.886IleGlu: 1.886 ± 0.559
5.028IlePhe: 5.028 ± 1.574
3.771IleGly: 3.771 ± 1.562
0.0IleHis: 0.0 ± 0.0
2.514IleIle: 2.514 ± 1.063
3.771IleLys: 3.771 ± 1.983
2.514IleLeu: 2.514 ± 1.041
3.143IleMet: 3.143 ± 0.814
1.886IleAsn: 1.886 ± 0.559
3.143IlePro: 3.143 ± 0.966
0.629IleGln: 0.629 ± 0.561
3.143IleArg: 3.143 ± 0.981
1.257IleSer: 1.257 ± 0.722
2.514IleThr: 2.514 ± 0.772
0.0IleVal: 0.0 ± 0.0
1.257IleTrp: 1.257 ± 0.531
2.514IleTyr: 2.514 ± 1.444
0.0IleXaa: 0.0 ± 0.0
Lys
0.0LysAla: 0.0 ± 0.0
2.514LysCys: 2.514 ± 1.856
4.4LysAsp: 4.4 ± 1.267
1.886LysGlu: 1.886 ± 1.054
2.514LysPhe: 2.514 ± 1.163
1.257LysGly: 1.257 ± 0.918
1.886LysHis: 1.886 ± 1.736
4.4LysIle: 4.4 ± 1.862
3.771LysLys: 3.771 ± 1.639
1.257LysLeu: 1.257 ± 1.485
1.257LysMet: 1.257 ± 0.964
2.514LysAsn: 2.514 ± 1.041
1.886LysPro: 1.886 ± 0.798
5.028LysGln: 5.028 ± 2.689
3.143LysArg: 3.143 ± 0.981
5.028LysSer: 5.028 ± 1.079
5.657LysThr: 5.657 ± 2.304
3.771LysVal: 3.771 ± 1.537
0.629LysTrp: 0.629 ± 0.54
5.028LysTyr: 5.028 ± 1.763
0.0LysXaa: 0.0 ± 0.0
Leu
5.028LeuAla: 5.028 ± 1.803
1.257LeuCys: 1.257 ± 1.485
6.914LeuAsp: 6.914 ± 2.403
5.028LeuGlu: 5.028 ± 2.286
2.514LeuPhe: 2.514 ± 1.163
4.4LeuGly: 4.4 ± 1.742
1.257LeuHis: 1.257 ± 0.928
2.514LeuIle: 2.514 ± 1.111
4.4LeuLys: 4.4 ± 0.873
1.886LeuLeu: 1.886 ± 1.402
3.771LeuMet: 3.771 ± 2.039
5.028LeuAsn: 5.028 ± 1.545
3.143LeuPro: 3.143 ± 1.485
5.028LeuGln: 5.028 ± 1.112
5.028LeuArg: 5.028 ± 0.728
5.028LeuSer: 5.028 ± 1.298
5.028LeuThr: 5.028 ± 1.426
3.771LeuVal: 3.771 ± 2.007
0.629LeuTrp: 0.629 ± 0.561
3.771LeuTyr: 3.771 ± 1.074
0.0LeuXaa: 0.0 ± 0.0
Met
4.4MetAla: 4.4 ± 2.15
0.629MetCys: 0.629 ± 0.54
3.143MetAsp: 3.143 ± 2.618
1.886MetGlu: 1.886 ± 0.959
1.257MetPhe: 1.257 ± 0.739
1.257MetGly: 1.257 ± 0.531
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.886MetLys: 1.886 ± 0.559
1.257MetLeu: 1.257 ± 0.948
0.0MetMet: 0.0 ± 0.0
1.886MetAsn: 1.886 ± 0.559
0.629MetPro: 0.629 ± 0.426
1.257MetGln: 1.257 ± 0.521
1.886MetArg: 1.886 ± 1.289
2.514MetSer: 2.514 ± 1.409
1.257MetThr: 1.257 ± 0.899
1.886MetVal: 1.886 ± 1.278
0.0MetTrp: 0.0 ± 0.0
1.257MetTyr: 1.257 ± 0.862
0.0MetXaa: 0.0 ± 0.0
Asn
8.171AsnAla: 8.171 ± 2.098
0.629AsnCys: 0.629 ± 0.743
2.514AsnAsp: 2.514 ± 0.986
5.657AsnGlu: 5.657 ± 1.685
2.514AsnPhe: 2.514 ± 1.288
5.657AsnGly: 5.657 ± 2.555
0.0AsnHis: 0.0 ± 0.0
5.028AsnIle: 5.028 ± 2.256
2.514AsnLys: 2.514 ± 0.665
3.143AsnLeu: 3.143 ± 0.936
0.0AsnMet: 0.0 ± 0.0
2.514AsnAsn: 2.514 ± 1.163
2.514AsnPro: 2.514 ± 0.949
1.886AsnGln: 1.886 ± 1.682
0.629AsnArg: 0.629 ± 0.874
3.143AsnSer: 3.143 ± 0.735
6.285AsnThr: 6.285 ± 2.188
1.886AsnVal: 1.886 ± 0.559
0.629AsnTrp: 0.629 ± 0.426
1.257AsnTyr: 1.257 ± 0.863
0.0AsnXaa: 0.0 ± 0.0
Pro
1.886ProAla: 1.886 ± 0.768
1.257ProCys: 1.257 ± 0.531
3.143ProAsp: 3.143 ± 1.965
3.771ProGlu: 3.771 ± 1.595
2.514ProPhe: 2.514 ± 1.063
1.257ProGly: 1.257 ± 0.852
0.629ProHis: 0.629 ± 0.54
0.629ProIle: 0.629 ± 0.54
3.771ProLys: 3.771 ± 1.259
3.143ProLeu: 3.143 ± 1.147
2.514ProMet: 2.514 ± 0.986
1.257ProAsn: 1.257 ± 0.852
1.886ProPro: 1.886 ± 0.983
1.886ProGln: 1.886 ± 0.994
2.514ProArg: 2.514 ± 1.055
3.143ProSer: 3.143 ± 1.111
1.886ProThr: 1.886 ± 0.768
3.143ProVal: 3.143 ± 1.56
0.629ProTrp: 0.629 ± 0.426
0.629ProTyr: 0.629 ± 0.426
0.0ProXaa: 0.0 ± 0.0
Gln
3.771GlnAla: 3.771 ± 1.989
0.0GlnCys: 0.0 ± 0.0
1.257GlnAsp: 1.257 ± 0.521
3.143GlnGlu: 3.143 ± 2.575
2.514GlnPhe: 2.514 ± 1.111
3.143GlnGly: 3.143 ± 0.983
0.629GlnHis: 0.629 ± 0.54
1.257GlnIle: 1.257 ± 0.852
2.514GlnLys: 2.514 ± 1.28
3.143GlnLeu: 3.143 ± 1.24
1.886GlnMet: 1.886 ± 0.959
3.143GlnAsn: 3.143 ± 1.518
0.629GlnPro: 0.629 ± 0.561
3.143GlnGln: 3.143 ± 1.557
3.143GlnArg: 3.143 ± 0.966
4.4GlnSer: 4.4 ± 2.233
2.514GlnThr: 2.514 ± 1.128
0.629GlnVal: 0.629 ± 0.426
0.0GlnTrp: 0.0 ± 0.0
3.771GlnTyr: 3.771 ± 1.691
0.0GlnXaa: 0.0 ± 0.0
Arg
7.542ArgAla: 7.542 ± 2.496
1.257ArgCys: 1.257 ± 1.327
1.257ArgAsp: 1.257 ± 0.531
5.028ArgGlu: 5.028 ± 1.812
4.4ArgPhe: 4.4 ± 0.681
1.257ArgGly: 1.257 ± 0.521
0.0ArgHis: 0.0 ± 0.0
2.514ArgIle: 2.514 ± 1.063
4.4ArgLys: 4.4 ± 2.153
5.028ArgLeu: 5.028 ± 1.378
1.886ArgMet: 1.886 ± 1.102
3.143ArgAsn: 3.143 ± 1.48
2.514ArgPro: 2.514 ± 1.063
3.143ArgGln: 3.143 ± 1.281
3.771ArgArg: 3.771 ± 2.376
6.285ArgSer: 6.285 ± 2.648
1.257ArgThr: 1.257 ± 0.877
4.4ArgVal: 4.4 ± 2.47
1.257ArgTrp: 1.257 ± 0.852
3.771ArgTyr: 3.771 ± 1.706
0.0ArgXaa: 0.0 ± 0.0
Ser
5.028SerAla: 5.028 ± 1.797
0.0SerCys: 0.0 ± 0.0
1.257SerAsp: 1.257 ± 0.863
3.143SerGlu: 3.143 ± 1.109
3.771SerPhe: 3.771 ± 1.444
5.657SerGly: 5.657 ± 3.408
0.629SerHis: 0.629 ± 0.743
6.914SerIle: 6.914 ± 2.162
6.285SerLys: 6.285 ± 1.252
11.942SerLeu: 11.942 ± 3.304
2.514SerMet: 2.514 ± 0.949
5.028SerAsn: 5.028 ± 1.191
3.143SerPro: 3.143 ± 1.222
4.4SerGln: 4.4 ± 1.742
2.514SerArg: 2.514 ± 1.755
2.514SerSer: 2.514 ± 1.79
3.143SerThr: 3.143 ± 1.467
5.028SerVal: 5.028 ± 1.622
0.629SerTrp: 0.629 ± 0.743
1.886SerTyr: 1.886 ± 0.698
0.0SerXaa: 0.0 ± 0.0
Thr
3.143ThrAla: 3.143 ± 1.342
1.886ThrCys: 1.886 ± 1.23
1.257ThrAsp: 1.257 ± 0.521
3.143ThrGlu: 3.143 ± 1.48
3.771ThrPhe: 3.771 ± 1.174
3.143ThrGly: 3.143 ± 1.965
1.257ThrHis: 1.257 ± 0.852
0.629ThrIle: 0.629 ± 0.743
1.886ThrLys: 1.886 ± 0.559
3.771ThrLeu: 3.771 ± 1.085
0.629ThrMet: 0.629 ± 0.874
0.629ThrAsn: 0.629 ± 0.54
5.028ThrPro: 5.028 ± 1.462
1.886ThrGln: 1.886 ± 0.994
3.143ThrArg: 3.143 ± 1.754
8.799ThrSer: 8.799 ± 2.939
3.143ThrThr: 3.143 ± 2.129
3.143ThrVal: 3.143 ± 1.238
0.0ThrTrp: 0.0 ± 0.0
3.143ThrTyr: 3.143 ± 1.287
0.0ThrXaa: 0.0 ± 0.0
Val
1.886ValAla: 1.886 ± 0.806
0.0ValCys: 0.0 ± 0.0
3.143ValAsp: 3.143 ± 0.66
0.629ValGlu: 0.629 ± 0.426
3.143ValPhe: 3.143 ± 0.91
1.257ValGly: 1.257 ± 0.521
2.514ValHis: 2.514 ± 1.704
0.629ValIle: 0.629 ± 0.54
2.514ValLys: 2.514 ± 0.968
5.028ValLeu: 5.028 ± 1.378
1.886ValMet: 1.886 ± 1.278
5.028ValAsn: 5.028 ± 2.293
8.171ValPro: 8.171 ± 3.142
3.143ValGln: 3.143 ± 0.91
5.657ValArg: 5.657 ± 1.33
6.285ValSer: 6.285 ± 3.102
5.028ValThr: 5.028 ± 1.206
1.257ValVal: 1.257 ± 0.531
0.629ValTrp: 0.629 ± 0.426
1.886ValTyr: 1.886 ± 0.698
0.0ValXaa: 0.0 ± 0.0
Trp
0.629TrpAla: 0.629 ± 0.426
0.0TrpCys: 0.0 ± 0.0
0.629TrpAsp: 0.629 ± 0.426
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.629TrpIle: 0.629 ± 0.54
2.514TrpLys: 2.514 ± 1.128
1.257TrpLeu: 1.257 ± 0.521
0.0TrpMet: 0.0 ± 0.0
2.514TrpAsn: 2.514 ± 0.968
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
1.257TrpSer: 1.257 ± 0.928
0.0TrpThr: 0.0 ± 0.0
0.629TrpVal: 0.629 ± 0.426
0.0TrpTrp: 0.0 ± 0.0
1.886TrpTyr: 1.886 ± 0.724
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.886TyrAla: 1.886 ± 1.25
1.257TyrCys: 1.257 ± 1.079
4.4TyrAsp: 4.4 ± 3.014
3.771TyrGlu: 3.771 ± 1.934
3.143TyrPhe: 3.143 ± 1.342
2.514TyrGly: 2.514 ± 0.968
1.257TyrHis: 1.257 ± 0.531
1.886TyrIle: 1.886 ± 1.518
2.514TyrLys: 2.514 ± 0.713
3.771TyrLeu: 3.771 ± 1.706
0.629TyrMet: 0.629 ± 0.561
3.143TyrAsn: 3.143 ± 0.983
0.0TyrPro: 0.0 ± 0.0
0.0TyrGln: 0.0 ± 0.0
2.514TyrArg: 2.514 ± 0.665
6.914TyrSer: 6.914 ± 2.675
2.514TyrThr: 2.514 ± 1.658
5.657TyrVal: 5.657 ± 1.163
2.514TyrTrp: 2.514 ± 0.665
2.514TyrTyr: 2.514 ± 1.345
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1592 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski