Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires;

Average proteome isoelectric point is 6.7

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 45022 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A2K5MS98|A0A2K5MS98_CERAT Centromere protein A OS=Cercocebus atys OX=9531 GN=CENPA PE=3 SV=1
MM1 pKa = 7.44GNVLTCCVCPKK12 pKa = 10.26VSSNCGWHH20 pKa = 5.81SGKK23 pKa = 10.16LASSYY28 pKa = 11.03EE29 pKa = 3.93SDD31 pKa = 3.58FYY33 pKa = 11.61EE34 pKa = 4.52VVAAATSEE42 pKa = 4.32STTVEE47 pKa = 4.0PGKK50 pKa = 10.53LDD52 pKa = 3.35VGATEE57 pKa = 5.0DD58 pKa = 4.46HH59 pKa = 7.0DD60 pKa = 4.16LQHH63 pKa = 7.07ISNQKK68 pKa = 8.81MPTGSPEE75 pKa = 4.02DD76 pKa = 3.78SLSLKK81 pKa = 10.28SLPPSEE87 pKa = 4.97EE88 pKa = 4.52DD89 pKa = 3.84NDD91 pKa = 4.08DD92 pKa = 3.9AQILPSRR99 pKa = 11.84FQASPEE105 pKa = 4.26DD106 pKa = 3.58NLSFVSLSRR115 pKa = 11.84NEE117 pKa = 5.49DD118 pKa = 3.33YY119 pKa = 11.47DD120 pKa = 6.35DD121 pKa = 6.72DD122 pKa = 7.45DD123 pKa = 7.6DD124 pKa = 7.69DD125 pKa = 7.64DD126 pKa = 7.35DD127 pKa = 7.52DD128 pKa = 7.51DD129 pKa = 5.22DD130 pKa = 5.27AQILPSRR137 pKa = 11.84VRR139 pKa = 11.84DD140 pKa = 3.51GCYY143 pKa = 10.25KK144 pKa = 10.28FDD146 pKa = 3.88SSCSSGYY153 pKa = 10.04NLSLVTPPPSEE164 pKa = 6.24DD165 pKa = 3.71YY166 pKa = 11.33DD167 pKa = 5.43CDD169 pKa = 6.07DD170 pKa = 5.56DD171 pKa = 7.2DD172 pKa = 6.23EE173 pKa = 7.62DD174 pKa = 6.9DD175 pKa = 5.11DD176 pKa = 4.9VQILPSRR183 pKa = 11.84VQAWPEE189 pKa = 3.47DD190 pKa = 3.82RR191 pKa = 11.84LFLRR195 pKa = 11.84CSPRR199 pKa = 11.84YY200 pKa = 9.48KK201 pKa = 10.78DD202 pKa = 5.12EE203 pKa = 4.66EE204 pKa = 5.63DD205 pKa = 5.48DD206 pKa = 5.44DD207 pKa = 6.05AADD210 pKa = 5.08CDD212 pKa = 4.66DD213 pKa = 4.97DD214 pKa = 6.2CDD216 pKa = 4.03VHH218 pKa = 5.76ITAWNEE224 pKa = 3.33NDD226 pKa = 3.54LTLEE230 pKa = 4.44SISDD234 pKa = 3.95EE235 pKa = 4.19EE236 pKa = 4.45THH238 pKa = 6.98PGG240 pKa = 3.26

Molecular weight: 26.57 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A2K5L9H2|A0A2K5L9H2_CERAT Mitochondrial ribosomal protein L27 OS=Cercocebus atys OX=9531 GN=MRPL27 PE=3 SV=1
MM1 pKa = 7.1RR2 pKa = 11.84AKK4 pKa = 9.12WRR6 pKa = 11.84KK7 pKa = 9.1KK8 pKa = 9.32RR9 pKa = 11.84MRR11 pKa = 11.84RR12 pKa = 11.84LKK14 pKa = 10.08RR15 pKa = 11.84KK16 pKa = 8.21RR17 pKa = 11.84RR18 pKa = 11.84KK19 pKa = 8.46MRR21 pKa = 11.84QRR23 pKa = 11.84SKK25 pKa = 11.41

Molecular weight: 3.46 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

20883

24139

45022

24628997

12

34310

547.0

61.03

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.891 ± 0.011

2.2 ± 0.01

4.873 ± 0.008

7.225 ± 0.015

3.625 ± 0.01

6.452 ± 0.016

2.594 ± 0.007

4.419 ± 0.011

5.898 ± 0.017

9.845 ± 0.02

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.161 ± 0.006

3.671 ± 0.009

6.191 ± 0.016

4.8 ± 0.014

5.633 ± 0.009

8.311 ± 0.016

5.34 ± 0.015

6.011 ± 0.015

1.202 ± 0.005

2.654 ± 0.007
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski