Amino acid dipepetide frequency for Zymoseptoria tritici (strain CBS 115943 / IPO323) (Speckled leaf blotch fungus) (Septoria tritici)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.795AlaAla: 9.795 ± 0.065
1.14AlaCys: 1.14 ± 0.016
4.617AlaAsp: 4.617 ± 0.036
5.648AlaGlu: 5.648 ± 0.044
3.297AlaPhe: 3.297 ± 0.033
6.312AlaGly: 6.312 ± 0.046
1.871AlaHis: 1.871 ± 0.019
4.296AlaIle: 4.296 ± 0.033
4.485AlaLys: 4.485 ± 0.043
7.992AlaLeu: 7.992 ± 0.051
2.187AlaMet: 2.187 ± 0.022
3.144AlaAsn: 3.144 ± 0.025
4.911AlaPro: 4.911 ± 0.038
3.63AlaGln: 3.63 ± 0.034
5.322AlaArg: 5.322 ± 0.039
7.36AlaSer: 7.36 ± 0.051
5.523AlaThr: 5.523 ± 0.037
5.74AlaVal: 5.74 ± 0.042
1.229AlaTrp: 1.229 ± 0.017
2.257AlaTyr: 2.257 ± 0.021
0.0AlaXaa: 0.0 ± 0.0
Cys
1.035CysAla: 1.035 ± 0.016
0.259CysCys: 0.259 ± 0.009
0.674CysAsp: 0.674 ± 0.013
0.643CysGlu: 0.643 ± 0.012
0.547CysPhe: 0.547 ± 0.01
0.989CysGly: 0.989 ± 0.018
0.34CysHis: 0.34 ± 0.008
0.7CysIle: 0.7 ± 0.013
0.546CysLys: 0.546 ± 0.012
1.223CysLeu: 1.223 ± 0.015
0.288CysMet: 0.288 ± 0.009
0.426CysAsn: 0.426 ± 0.011
0.674CysPro: 0.674 ± 0.015
0.451CysGln: 0.451 ± 0.009
0.817CysArg: 0.817 ± 0.016
0.927CysSer: 0.927 ± 0.016
0.751CysThr: 0.751 ± 0.013
0.816CysVal: 0.816 ± 0.015
0.202CysTrp: 0.202 ± 0.007
0.357CysTyr: 0.357 ± 0.008
0.0CysXaa: 0.0 ± 0.0
Asp
5.113AspAla: 5.113 ± 0.039
0.67AspCys: 0.67 ± 0.011
4.473AspAsp: 4.473 ± 0.05
4.695AspGlu: 4.695 ± 0.042
2.335AspPhe: 2.335 ± 0.021
4.345AspGly: 4.345 ± 0.035
1.333AspHis: 1.333 ± 0.019
2.841AspIle: 2.841 ± 0.026
2.334AspLys: 2.334 ± 0.025
5.171AspLeu: 5.171 ± 0.037
1.315AspMet: 1.315 ± 0.017
1.822AspAsn: 1.822 ± 0.019
3.191AspPro: 3.191 ± 0.029
1.946AspGln: 1.946 ± 0.02
3.167AspArg: 3.167 ± 0.031
3.989AspSer: 3.989 ± 0.032
2.958AspThr: 2.958 ± 0.026
3.918AspVal: 3.918 ± 0.032
0.92AspTrp: 0.92 ± 0.014
1.542AspTyr: 1.542 ± 0.019
0.0AspXaa: 0.0 ± 0.0
Glu
5.618GluAla: 5.618 ± 0.046
0.663GluCys: 0.663 ± 0.012
4.554GluAsp: 4.554 ± 0.035
5.73GluGlu: 5.73 ± 0.052
1.854GluPhe: 1.854 ± 0.019
4.098GluGly: 4.098 ± 0.034
1.51GluHis: 1.51 ± 0.02
2.839GluIle: 2.839 ± 0.028
3.763GluLys: 3.763 ± 0.038
5.264GluLeu: 5.264 ± 0.042
1.599GluMet: 1.599 ± 0.02
2.076GluAsn: 2.076 ± 0.021
2.578GluPro: 2.578 ± 0.028
2.698GluGln: 2.698 ± 0.027
4.133GluArg: 4.133 ± 0.036
3.967GluSer: 3.967 ± 0.037
3.308GluThr: 3.308 ± 0.025
4.001GluVal: 4.001 ± 0.032
0.934GluTrp: 0.934 ± 0.014
1.612GluTyr: 1.612 ± 0.021
0.0GluXaa: 0.0 ± 0.0
Phe
3.325PheAla: 3.325 ± 0.03
0.55PheCys: 0.55 ± 0.012
2.326PheAsp: 2.326 ± 0.022
2.179PheGlu: 2.179 ± 0.024
1.531PhePhe: 1.531 ± 0.021
2.895PheGly: 2.895 ± 0.031
0.911PheHis: 0.911 ± 0.015
1.649PheIle: 1.649 ± 0.022
1.464PheLys: 1.464 ± 0.019
3.27PheLeu: 3.27 ± 0.032
0.748PheMet: 0.748 ± 0.014
1.392PheAsn: 1.392 ± 0.017
1.805PhePro: 1.805 ± 0.018
1.312PheGln: 1.312 ± 0.016
1.928PheArg: 1.928 ± 0.019
2.751PheSer: 2.751 ± 0.025
2.219PheThr: 2.219 ± 0.02
2.383PheVal: 2.383 ± 0.023
0.631PheTrp: 0.631 ± 0.013
1.048PheTyr: 1.048 ± 0.017
0.0PheXaa: 0.0 ± 0.0
Gly
5.48GlyAla: 5.48 ± 0.041
0.909GlyCys: 0.909 ± 0.016
3.764GlyAsp: 3.764 ± 0.031
4.051GlyGlu: 4.051 ± 0.03
2.781GlyPhe: 2.781 ± 0.03
6.486GlyGly: 6.486 ± 0.063
1.692GlyHis: 1.692 ± 0.02
3.344GlyIle: 3.344 ± 0.03
3.749GlyLys: 3.749 ± 0.034
6.069GlyLeu: 6.069 ± 0.04
1.807GlyMet: 1.807 ± 0.022
2.543GlyAsn: 2.543 ± 0.03
3.17GlyPro: 3.17 ± 0.032
2.623GlyGln: 2.623 ± 0.031
4.297GlyArg: 4.297 ± 0.032
5.543GlySer: 5.543 ± 0.051
4.001GlyThr: 4.001 ± 0.033
4.557GlyVal: 4.557 ± 0.038
1.202GlyTrp: 1.202 ± 0.019
2.104GlyTyr: 2.104 ± 0.024
0.0GlyXaa: 0.0 ± 0.0
His
2.101HisAla: 2.101 ± 0.02
0.373HisCys: 0.373 ± 0.009
1.424HisAsp: 1.424 ± 0.02
1.363HisGlu: 1.363 ± 0.017
0.969HisPhe: 0.969 ± 0.015
1.739HisGly: 1.739 ± 0.022
0.858HisHis: 0.858 ± 0.017
1.178HisIle: 1.178 ± 0.017
0.932HisLys: 0.932 ± 0.015
2.341HisLeu: 2.341 ± 0.023
0.482HisMet: 0.482 ± 0.01
0.867HisAsn: 0.867 ± 0.015
1.621HisPro: 1.621 ± 0.019
0.973HisGln: 0.973 ± 0.015
1.551HisArg: 1.551 ± 0.02
1.823HisSer: 1.823 ± 0.023
1.332HisThr: 1.332 ± 0.017
1.439HisVal: 1.439 ± 0.018
0.363HisTrp: 0.363 ± 0.009
0.673HisTyr: 0.673 ± 0.01
0.0HisXaa: 0.0 ± 0.0
Ile
4.371IleAla: 4.371 ± 0.036
0.728IleCys: 0.728 ± 0.014
2.82IleAsp: 2.82 ± 0.025
2.774IleGlu: 2.774 ± 0.025
1.877IlePhe: 1.877 ± 0.024
3.164IleGly: 3.164 ± 0.027
1.141IleHis: 1.141 ± 0.015
2.241IleIle: 2.241 ± 0.029
2.062IleLys: 2.062 ± 0.02
4.221IleLeu: 4.221 ± 0.036
0.993IleMet: 0.993 ± 0.014
1.668IleAsn: 1.668 ± 0.02
2.785IlePro: 2.785 ± 0.025
1.659IleGln: 1.659 ± 0.019
2.685IleArg: 2.685 ± 0.024
3.58IleSer: 3.58 ± 0.029
2.806IleThr: 2.806 ± 0.029
3.12IleVal: 3.12 ± 0.033
0.677IleTrp: 0.677 ± 0.013
1.323IleTyr: 1.323 ± 0.016
0.0IleXaa: 0.0 ± 0.0
Lys
4.588LysAla: 4.588 ± 0.045
0.523LysCys: 0.523 ± 0.011
2.973LysAsp: 2.973 ± 0.028
3.469LysGlu: 3.469 ± 0.037
1.435LysPhe: 1.435 ± 0.02
3.043LysGly: 3.043 ± 0.029
1.174LysHis: 1.174 ± 0.019
2.148LysIle: 2.148 ± 0.022
3.415LysLys: 3.415 ± 0.051
4.042LysLeu: 4.042 ± 0.039
1.095LysMet: 1.095 ± 0.017
1.645LysAsn: 1.645 ± 0.023
2.647LysPro: 2.647 ± 0.026
1.957LysGln: 1.957 ± 0.025
3.51LysArg: 3.51 ± 0.03
3.487LysSer: 3.487 ± 0.032
2.873LysThr: 2.873 ± 0.027
2.967LysVal: 2.967 ± 0.026
0.694LysTrp: 0.694 ± 0.014
1.284LysTyr: 1.284 ± 0.018
0.0LysXaa: 0.0 ± 0.0
Leu
8.104LeuAla: 8.104 ± 0.045
1.218LeuCys: 1.218 ± 0.017
5.089LeuAsp: 5.089 ± 0.036
5.411LeuGlu: 5.411 ± 0.043
3.126LeuPhe: 3.126 ± 0.029
5.722LeuGly: 5.722 ± 0.035
2.325LeuHis: 2.325 ± 0.024
3.776LeuIle: 3.776 ± 0.031
4.188LeuLys: 4.188 ± 0.035
8.239LeuLeu: 8.239 ± 0.055
1.787LeuMet: 1.787 ± 0.02
3.02LeuAsn: 3.02 ± 0.027
5.565LeuPro: 5.565 ± 0.042
3.853LeuGln: 3.853 ± 0.036
5.864LeuArg: 5.864 ± 0.042
6.893LeuSer: 6.893 ± 0.046
4.939LeuThr: 4.939 ± 0.036
5.242LeuVal: 5.242 ± 0.035
1.178LeuTrp: 1.178 ± 0.018
2.239LeuTyr: 2.239 ± 0.025
0.0LeuXaa: 0.0 ± 0.0
Met
2.298MetAla: 2.298 ± 0.026
0.277MetCys: 0.277 ± 0.008
1.298MetAsp: 1.298 ± 0.018
1.365MetGlu: 1.365 ± 0.019
0.759MetPhe: 0.759 ± 0.014
1.499MetGly: 1.499 ± 0.022
0.516MetHis: 0.516 ± 0.011
0.985MetIle: 0.985 ± 0.014
1.077MetLys: 1.077 ± 0.015
1.974MetLeu: 1.974 ± 0.022
0.587MetMet: 0.587 ± 0.011
0.79MetAsn: 0.79 ± 0.015
1.387MetPro: 1.387 ± 0.018
0.957MetGln: 0.957 ± 0.016
1.373MetArg: 1.373 ± 0.016
1.902MetSer: 1.902 ± 0.02
1.273MetThr: 1.273 ± 0.017
1.318MetVal: 1.318 ± 0.018
0.284MetTrp: 0.284 ± 0.008
0.558MetTyr: 0.558 ± 0.012
0.0MetXaa: 0.0 ± 0.0
Asn
3.36AsnAla: 3.36 ± 0.028
0.416AsnCys: 0.416 ± 0.01
2.065AsnAsp: 2.065 ± 0.02
2.0AsnGlu: 2.0 ± 0.02
1.347AsnPhe: 1.347 ± 0.018
3.121AsnGly: 3.121 ± 0.029
0.824AsnHis: 0.824 ± 0.014
1.909AsnIle: 1.909 ± 0.023
1.5AsnLys: 1.5 ± 0.019
3.034AsnLeu: 3.034 ± 0.029
0.804AsnMet: 0.804 ± 0.012
1.454AsnAsn: 1.454 ± 0.023
2.249AsnPro: 2.249 ± 0.023
1.175AsnGln: 1.175 ± 0.019
1.836AsnArg: 1.836 ± 0.02
2.544AsnSer: 2.544 ± 0.027
2.194AsnThr: 2.194 ± 0.025
2.35AsnVal: 2.35 ± 0.024
0.517AsnTrp: 0.517 ± 0.01
0.99AsnTyr: 0.99 ± 0.015
0.0AsnXaa: 0.0 ± 0.0
Pro
5.486ProAla: 5.486 ± 0.044
0.545ProCys: 0.545 ± 0.013
3.072ProAsp: 3.072 ± 0.025
3.534ProGlu: 3.534 ± 0.035
1.957ProPhe: 1.957 ± 0.018
3.773ProGly: 3.773 ± 0.034
1.331ProHis: 1.331 ± 0.018
2.441ProIle: 2.441 ± 0.025
2.608ProLys: 2.608 ± 0.027
4.443ProLeu: 4.443 ± 0.036
1.069ProMet: 1.069 ± 0.018
2.123ProAsn: 2.123 ± 0.02
4.997ProPro: 4.997 ± 0.073
2.372ProGln: 2.372 ± 0.033
3.248ProArg: 3.248 ± 0.03
5.671ProSer: 5.671 ± 0.047
4.057ProThr: 4.057 ± 0.032
3.268ProVal: 3.268 ± 0.026
0.708ProTrp: 0.708 ± 0.013
1.434ProTyr: 1.434 ± 0.021
0.0ProXaa: 0.0 ± 0.0
Gln
3.645GlnAla: 3.645 ± 0.035
0.474GlnCys: 0.474 ± 0.01
2.165GlnAsp: 2.165 ± 0.02
2.34GlnGlu: 2.34 ± 0.024
1.215GlnPhe: 1.215 ± 0.018
2.371GlnGly: 2.371 ± 0.028
1.192GlnHis: 1.192 ± 0.018
1.804GlnIle: 1.804 ± 0.02
1.967GlnLys: 1.967 ± 0.025
3.403GlnLeu: 3.403 ± 0.031
0.916GlnMet: 0.916 ± 0.016
1.501GlnAsn: 1.501 ± 0.021
2.416GlnPro: 2.416 ± 0.032
2.597GlnGln: 2.597 ± 0.062
2.78GlnArg: 2.78 ± 0.027
3.111GlnSer: 3.111 ± 0.034
2.439GlnThr: 2.439 ± 0.032
2.156GlnVal: 2.156 ± 0.022
0.565GlnTrp: 0.565 ± 0.011
1.197GlnTyr: 1.197 ± 0.019
0.0GlnXaa: 0.0 ± 0.0
Arg
5.008ArgAla: 5.008 ± 0.038
0.77ArgCys: 0.77 ± 0.014
3.365ArgAsp: 3.365 ± 0.031
3.97ArgGlu: 3.97 ± 0.041
2.114ArgPhe: 2.114 ± 0.023
3.814ArgGly: 3.814 ± 0.032
1.582ArgHis: 1.582 ± 0.02
2.874ArgIle: 2.874 ± 0.028
3.61ArgLys: 3.61 ± 0.029
5.461ArgLeu: 5.461 ± 0.038
1.458ArgMet: 1.458 ± 0.018
2.217ArgAsn: 2.217 ± 0.024
3.476ArgPro: 3.476 ± 0.031
2.699ArgGln: 2.699 ± 0.023
5.081ArgArg: 5.081 ± 0.051
4.886ArgSer: 4.886 ± 0.044
3.58ArgThr: 3.58 ± 0.031
3.347ArgVal: 3.347 ± 0.03
0.943ArgTrp: 0.943 ± 0.015
1.606ArgTyr: 1.606 ± 0.02
0.0ArgXaa: 0.0 ± 0.0
Ser
6.942SerAla: 6.942 ± 0.049
0.879SerCys: 0.879 ± 0.015
4.2SerAsp: 4.2 ± 0.033
4.019SerGlu: 4.019 ± 0.034
2.765SerPhe: 2.765 ± 0.022
5.538SerGly: 5.538 ± 0.044
1.872SerHis: 1.872 ± 0.022
3.8SerIle: 3.8 ± 0.03
3.671SerLys: 3.671 ± 0.034
6.727SerLeu: 6.727 ± 0.045
1.763SerMet: 1.763 ± 0.021
2.964SerAsn: 2.964 ± 0.029
5.016SerPro: 5.016 ± 0.055
3.073SerGln: 3.073 ± 0.037
4.846SerArg: 4.846 ± 0.042
8.229SerSer: 8.229 ± 0.117
5.818SerThr: 5.818 ± 0.066
4.345SerVal: 4.345 ± 0.033
1.059SerTrp: 1.059 ± 0.017
1.95SerTyr: 1.95 ± 0.023
0.0SerXaa: 0.0 ± 0.0
Thr
5.706ThrAla: 5.706 ± 0.036
0.796ThrCys: 0.796 ± 0.015
2.895ThrAsp: 2.895 ± 0.028
3.019ThrGlu: 3.019 ± 0.028
2.363ThrPhe: 2.363 ± 0.024
4.204ThrGly: 4.204 ± 0.041
1.354ThrHis: 1.354 ± 0.015
3.107ThrIle: 3.107 ± 0.026
2.698ThrLys: 2.698 ± 0.025
5.36ThrLeu: 5.36 ± 0.037
1.279ThrMet: 1.279 ± 0.018
2.14ThrAsn: 2.14 ± 0.023
4.186ThrPro: 4.186 ± 0.032
2.119ThrGln: 2.119 ± 0.026
3.185ThrArg: 3.185 ± 0.025
5.535ThrSer: 5.535 ± 0.053
4.688ThrThr: 4.688 ± 0.051
3.622ThrVal: 3.622 ± 0.032
0.855ThrTrp: 0.855 ± 0.015
1.627ThrTyr: 1.627 ± 0.018
0.0ThrXaa: 0.0 ± 0.0
Val
5.42ValAla: 5.42 ± 0.04
0.838ValCys: 0.838 ± 0.013
3.757ValAsp: 3.757 ± 0.032
4.257ValGlu: 4.257 ± 0.032
2.376ValPhe: 2.376 ± 0.031
4.159ValGly: 4.159 ± 0.034
1.452ValHis: 1.452 ± 0.019
2.699ValIle: 2.699 ± 0.027
3.066ValLys: 3.066 ± 0.028
5.696ValLeu: 5.696 ± 0.036
1.349ValMet: 1.349 ± 0.017
2.181ValAsn: 2.181 ± 0.025
3.438ValPro: 3.438 ± 0.028
2.46ValGln: 2.46 ± 0.024
3.646ValArg: 3.646 ± 0.032
4.283ValSer: 4.283 ± 0.034
3.339ValThr: 3.339 ± 0.029
4.408ValVal: 4.408 ± 0.035
0.905ValTrp: 0.905 ± 0.015
1.667ValTyr: 1.667 ± 0.019
0.0ValXaa: 0.0 ± 0.0
Trp
1.1TrpAla: 1.1 ± 0.015
0.214TrpCys: 0.214 ± 0.007
0.865TrpAsp: 0.865 ± 0.016
0.844TrpGlu: 0.844 ± 0.014
0.538TrpPhe: 0.538 ± 0.012
0.832TrpGly: 0.832 ± 0.015
0.381TrpHis: 0.381 ± 0.01
0.746TrpIle: 0.746 ± 0.013
0.788TrpLys: 0.788 ± 0.012
1.355TrpLeu: 1.355 ± 0.02
0.378TrpMet: 0.378 ± 0.008
0.614TrpAsn: 0.614 ± 0.011
0.616TrpPro: 0.616 ± 0.013
0.632TrpGln: 0.632 ± 0.012
1.037TrpArg: 1.037 ± 0.017
1.101TrpSer: 1.101 ± 0.015
1.003TrpThr: 1.003 ± 0.014
0.828TrpVal: 0.828 ± 0.013
0.269TrpTrp: 0.269 ± 0.008
0.423TrpTyr: 0.423 ± 0.011
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.26TyrAla: 2.26 ± 0.025
0.422TyrCys: 0.422 ± 0.01
1.682TyrAsp: 1.682 ± 0.022
1.49TyrGlu: 1.49 ± 0.018
1.132TyrPhe: 1.132 ± 0.016
2.069TyrGly: 2.069 ± 0.024
0.743TyrHis: 0.743 ± 0.014
1.314TyrIle: 1.314 ± 0.017
1.049TyrLys: 1.049 ± 0.016
2.494TyrLeu: 2.494 ± 0.026
0.572TyrMet: 0.572 ± 0.012
1.104TyrAsn: 1.104 ± 0.014
1.405TyrPro: 1.405 ± 0.019
1.067TyrGln: 1.067 ± 0.016
1.556TyrArg: 1.556 ± 0.02
1.895TyrSer: 1.895 ± 0.024
1.637TyrThr: 1.637 ± 0.022
1.572TyrVal: 1.572 ± 0.019
0.431TyrTrp: 0.431 ± 0.01
0.884TyrTyr: 0.884 ± 0.016
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 10972 proteins (4798142 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski