Amino acid dipepetide frequency for Beihai picorna-like virus 112

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.506AlaAla: 4.506 ± 1.231
0.901AlaCys: 0.901 ± 0.128
2.103AlaAsp: 2.103 ± 0.49
5.107AlaGlu: 5.107 ± 0.922
3.004AlaPhe: 3.004 ± 0.229
3.605AlaGly: 3.605 ± 2.877
0.901AlaHis: 0.901 ± 0.463
5.707AlaIle: 5.707 ± 1.205
4.506AlaLys: 4.506 ± 1.725
5.407AlaLeu: 5.407 ± 0.177
1.202AlaMet: 1.202 ± 0.799
1.502AlaAsn: 1.502 ± 0.41
2.704AlaPro: 2.704 ± 0.799
2.403AlaGln: 2.403 ± 1.129
2.103AlaArg: 2.103 ± 0.101
5.107AlaSer: 5.107 ± 0.331
4.205AlaThr: 4.205 ± 0.203
5.107AlaVal: 5.107 ± 3.878
0.901AlaTrp: 0.901 ± 0.463
2.704AlaTyr: 2.704 ± 0.799
0.0AlaXaa: 0.0 ± 0.0
Cys
0.601CysAla: 0.601 ± 0.309
0.0CysCys: 0.0 ± 0.0
1.502CysAsp: 1.502 ± 0.772
1.502CysGlu: 1.502 ± 0.772
0.601CysPhe: 0.601 ± 0.282
1.202CysGly: 1.202 ± 0.618
0.0CysHis: 0.0 ± 0.0
0.3CysIle: 0.3 ± 0.437
1.202CysLys: 1.202 ± 0.618
1.202CysLeu: 1.202 ± 0.026
0.601CysMet: 0.601 ± 0.309
0.901CysAsn: 0.901 ± 0.128
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.802CysArg: 1.802 ± 0.335
0.3CysSer: 0.3 ± 0.154
0.0CysThr: 0.0 ± 0.0
1.502CysVal: 1.502 ± 0.181
0.601CysTrp: 0.601 ± 0.282
0.601CysTyr: 0.601 ± 0.309
0.0CysXaa: 0.0 ± 0.0
Asp
3.905AspAla: 3.905 ± 0.949
1.502AspCys: 1.502 ± 0.772
4.205AspAsp: 4.205 ± 0.979
4.506AspGlu: 4.506 ± 1.725
3.605AspPhe: 3.605 ± 0.079
4.205AspGly: 4.205 ± 1.385
1.502AspHis: 1.502 ± 0.772
3.304AspIle: 3.304 ± 0.075
2.704AspLys: 2.704 ± 0.975
4.205AspLeu: 4.205 ± 0.388
0.601AspMet: 0.601 ± 0.282
1.802AspAsn: 1.802 ± 0.335
2.403AspPro: 2.403 ± 0.538
1.502AspGln: 1.502 ± 0.181
3.905AspArg: 3.905 ± 0.825
3.304AspSer: 3.304 ± 0.075
3.605AspThr: 3.605 ± 0.512
4.806AspVal: 4.806 ± 0.485
1.202AspTrp: 1.202 ± 0.618
2.103AspTyr: 2.103 ± 1.081
0.0AspXaa: 0.0 ± 0.0
Glu
3.905GluAla: 3.905 ± 0.234
0.901GluCys: 0.901 ± 0.463
3.605GluAsp: 3.605 ± 0.671
6.008GluGlu: 6.008 ± 0.132
2.704GluPhe: 2.704 ± 0.799
3.304GluGly: 3.304 ± 0.666
2.403GluHis: 2.403 ± 0.644
3.905GluIle: 3.905 ± 1.54
3.905GluLys: 3.905 ± 2.007
7.209GluLeu: 7.209 ± 1.615
2.704GluMet: 2.704 ± 0.207
2.103GluAsn: 2.103 ± 0.49
3.004GluPro: 3.004 ± 0.229
1.202GluGln: 1.202 ± 0.618
4.205GluArg: 4.205 ± 0.979
4.506GluSer: 4.506 ± 1.822
3.004GluThr: 3.004 ± 0.821
6.008GluVal: 6.008 ± 1.05
0.3GluTrp: 0.3 ± 0.154
1.502GluTyr: 1.502 ± 0.772
0.0GluXaa: 0.0 ± 0.0
Phe
3.004PheAla: 3.004 ± 0.229
0.0PheCys: 0.0 ± 0.0
4.506PheAsp: 4.506 ± 0.543
3.004PheGlu: 3.004 ± 0.362
1.802PhePhe: 1.802 ± 0.256
1.502PheGly: 1.502 ± 0.41
1.202PheHis: 1.202 ± 1.156
3.004PheIle: 3.004 ± 0.229
4.506PheLys: 4.506 ± 1.134
5.407PheLeu: 5.407 ± 1.597
1.202PheMet: 1.202 ± 0.559
1.502PheAsn: 1.502 ± 0.181
3.605PhePro: 3.605 ± 0.512
3.004PheGln: 3.004 ± 1.544
2.704PheArg: 2.704 ± 0.384
5.107PheSer: 5.107 ± 0.331
1.802PheThr: 1.802 ± 0.335
3.304PheVal: 3.304 ± 0.666
0.901PheTrp: 0.901 ± 0.128
1.502PheTyr: 1.502 ± 0.772
0.0PheXaa: 0.0 ± 0.0
Gly
3.304GlyAla: 3.304 ± 1.849
0.901GlyCys: 0.901 ± 0.128
3.905GlyAsp: 3.905 ± 0.357
1.502GlyGlu: 1.502 ± 0.41
2.403GlyPhe: 2.403 ± 0.644
3.004GlyGly: 3.004 ± 1.412
1.202GlyHis: 1.202 ± 0.026
3.605GlyIle: 3.605 ± 1.853
4.205GlyLys: 4.205 ± 0.388
3.605GlyLeu: 3.605 ± 1.262
1.802GlyMet: 1.802 ± 0.847
1.802GlyAsn: 1.802 ± 0.335
2.704GlyPro: 2.704 ± 0.799
3.004GlyGln: 3.004 ± 0.821
3.004GlyArg: 3.004 ± 0.229
5.407GlySer: 5.407 ± 1.95
2.103GlyThr: 2.103 ± 0.101
3.304GlyVal: 3.304 ± 1.257
0.601GlyTrp: 0.601 ± 0.282
2.403GlyTyr: 2.403 ± 0.053
0.0GlyXaa: 0.0 ± 0.0
His
0.3HisAla: 0.3 ± 0.154
0.0HisCys: 0.0 ± 0.0
0.901HisAsp: 0.901 ± 0.128
0.601HisGlu: 0.601 ± 0.309
1.502HisPhe: 1.502 ± 1.002
1.502HisGly: 1.502 ± 0.772
0.0HisHis: 0.0 ± 0.0
2.403HisIle: 2.403 ± 1.235
1.502HisLys: 1.502 ± 0.772
3.304HisLeu: 3.304 ± 0.075
1.502HisMet: 1.502 ± 1.002
1.202HisAsn: 1.202 ± 0.618
0.601HisPro: 0.601 ± 0.309
0.901HisGln: 0.901 ± 0.128
2.103HisArg: 2.103 ± 0.101
2.704HisSer: 2.704 ± 0.207
1.502HisThr: 1.502 ± 0.181
0.901HisVal: 0.901 ± 0.463
0.3HisTrp: 0.3 ± 0.437
1.202HisTyr: 1.202 ± 0.026
0.0HisXaa: 0.0 ± 0.0
Ile
3.605IleAla: 3.605 ± 0.671
0.0IleCys: 0.0 ± 0.0
4.205IleAsp: 4.205 ± 0.388
3.605IleGlu: 3.605 ± 0.079
3.004IlePhe: 3.004 ± 0.229
3.304IleGly: 3.304 ± 1.257
0.901IleHis: 0.901 ± 0.463
3.905IleIle: 3.905 ± 1.416
4.506IleLys: 4.506 ± 0.64
4.506IleLeu: 4.506 ± 0.64
0.901IleMet: 0.901 ± 0.463
2.704IleAsn: 2.704 ± 0.207
4.205IlePro: 4.205 ± 0.203
2.103IleGln: 2.103 ± 1.284
1.802IleArg: 1.802 ± 1.438
3.905IleSer: 3.905 ± 0.357
4.506IleThr: 4.506 ± 0.64
3.605IleVal: 3.605 ± 0.079
0.601IleTrp: 0.601 ± 0.309
0.601IleTyr: 0.601 ± 0.309
0.0IleXaa: 0.0 ± 0.0
Lys
2.103LysAla: 2.103 ± 0.49
0.601LysCys: 0.601 ± 0.309
3.605LysAsp: 3.605 ± 1.262
8.411LysGlu: 8.411 ± 1.368
3.905LysPhe: 3.905 ± 1.416
3.905LysGly: 3.905 ± 1.416
2.704LysHis: 2.704 ± 0.207
2.704LysIle: 2.704 ± 0.207
4.506LysLys: 4.506 ± 0.049
4.506LysLeu: 4.506 ± 0.543
1.202LysMet: 1.202 ± 0.618
2.704LysAsn: 2.704 ± 0.207
3.304LysPro: 3.304 ± 0.075
3.605LysGln: 3.605 ± 0.512
3.605LysArg: 3.605 ± 0.512
6.008LysSer: 6.008 ± 1.315
4.205LysThr: 4.205 ± 0.203
3.304LysVal: 3.304 ± 1.107
1.202LysTrp: 1.202 ± 0.565
1.502LysTyr: 1.502 ± 0.181
0.0LysXaa: 0.0 ± 0.0
Leu
7.51LeuAla: 7.51 ± 0.904
1.202LeuCys: 1.202 ± 0.618
5.107LeuAsp: 5.107 ± 0.922
3.905LeuGlu: 3.905 ± 1.54
4.205LeuPhe: 4.205 ± 0.388
3.004LeuGly: 3.004 ± 1.544
2.403LeuHis: 2.403 ± 0.644
6.008LeuIle: 6.008 ± 0.132
6.609LeuLys: 6.609 ± 0.441
8.111LeuLeu: 8.111 ± 0.031
1.802LeuMet: 1.802 ± 0.335
3.605LeuAsn: 3.605 ± 1.853
4.806LeuPro: 4.806 ± 1.077
2.403LeuGln: 2.403 ± 0.053
3.605LeuArg: 3.605 ± 0.079
6.609LeuSer: 6.609 ± 0.441
5.407LeuThr: 5.407 ± 0.415
4.506LeuVal: 4.506 ± 0.64
0.901LeuTrp: 0.901 ± 0.128
1.802LeuTyr: 1.802 ± 0.847
0.0LeuXaa: 0.0 ± 0.0
Met
1.502MetAla: 1.502 ± 0.41
0.901MetCys: 0.901 ± 0.463
0.3MetAsp: 0.3 ± 0.154
2.103MetGlu: 2.103 ± 0.693
1.502MetPhe: 1.502 ± 0.41
1.502MetGly: 1.502 ± 0.181
0.3MetHis: 0.3 ± 0.154
1.802MetIle: 1.802 ± 0.847
1.502MetLys: 1.502 ± 0.772
1.502MetLeu: 1.502 ± 0.772
0.901MetMet: 0.901 ± 0.463
0.601MetAsn: 0.601 ± 0.309
1.502MetPro: 1.502 ± 1.002
0.601MetGln: 0.601 ± 0.309
0.601MetArg: 0.601 ± 0.282
1.502MetSer: 1.502 ± 0.41
1.802MetThr: 1.802 ± 0.335
2.704MetVal: 2.704 ± 0.207
0.901MetTrp: 0.901 ± 0.128
0.901MetTyr: 0.901 ± 0.128
0.0MetXaa: 0.0 ± 0.0
Asn
3.004AsnAla: 3.004 ± 0.362
0.901AsnCys: 0.901 ± 0.128
1.502AsnAsp: 1.502 ± 0.41
2.103AsnGlu: 2.103 ± 0.101
2.704AsnPhe: 2.704 ± 0.975
1.202AsnGly: 1.202 ± 0.618
0.3AsnHis: 0.3 ± 0.154
3.004AsnIle: 3.004 ± 0.362
1.802AsnLys: 1.802 ± 0.335
3.004AsnLeu: 3.004 ± 0.953
1.202AsnMet: 1.202 ± 0.618
2.403AsnAsn: 2.403 ± 0.053
1.202AsnPro: 1.202 ± 0.618
1.802AsnGln: 1.802 ± 0.256
2.403AsnArg: 2.403 ± 0.053
1.202AsnSer: 1.202 ± 0.618
1.502AsnThr: 1.502 ± 0.181
3.004AsnVal: 3.004 ± 0.362
0.901AsnTrp: 0.901 ± 0.128
2.403AsnTyr: 2.403 ± 0.538
0.0AsnXaa: 0.0 ± 0.0
Pro
3.304ProAla: 3.304 ± 3.031
0.3ProCys: 0.3 ± 0.154
4.506ProAsp: 4.506 ± 1.231
3.004ProGlu: 3.004 ± 0.362
2.103ProPhe: 2.103 ± 0.101
3.304ProGly: 3.304 ± 0.075
0.901ProHis: 0.901 ± 0.719
0.601ProIle: 0.601 ± 0.282
3.004ProLys: 3.004 ± 0.362
3.905ProLeu: 3.905 ± 0.234
1.202ProMet: 1.202 ± 0.026
1.202ProAsn: 1.202 ± 0.026
2.704ProPro: 2.704 ± 0.975
3.004ProGln: 3.004 ± 0.229
3.004ProArg: 3.004 ± 0.953
3.605ProSer: 3.605 ± 0.671
2.704ProThr: 2.704 ± 0.207
3.304ProVal: 3.304 ± 1.107
1.202ProTrp: 1.202 ± 0.618
1.202ProTyr: 1.202 ± 0.565
0.0ProXaa: 0.0 ± 0.0
Gln
1.502GlnAla: 1.502 ± 1.002
0.901GlnCys: 0.901 ± 0.128
1.202GlnAsp: 1.202 ± 0.026
3.905GlnGlu: 3.905 ± 0.357
1.802GlnPhe: 1.802 ± 0.847
2.103GlnGly: 2.103 ± 0.101
0.901GlnHis: 0.901 ± 1.31
1.202GlnIle: 1.202 ± 0.618
3.304GlnLys: 3.304 ± 0.075
3.004GlnLeu: 3.004 ± 0.362
0.601GlnMet: 0.601 ± 0.874
0.901GlnAsn: 0.901 ± 0.128
1.502GlnPro: 1.502 ± 0.181
2.704GlnGln: 2.704 ± 0.799
3.304GlnArg: 3.304 ± 0.516
4.506GlnSer: 4.506 ± 0.543
3.004GlnThr: 3.004 ± 0.229
1.802GlnVal: 1.802 ± 0.847
0.601GlnTrp: 0.601 ± 0.309
1.802GlnTyr: 1.802 ± 0.256
0.0GlnXaa: 0.0 ± 0.0
Arg
4.205ArgAla: 4.205 ± 0.794
0.601ArgCys: 0.601 ± 0.282
3.004ArgAsp: 3.004 ± 0.362
3.905ArgGlu: 3.905 ± 0.357
3.304ArgPhe: 3.304 ± 0.075
2.103ArgGly: 2.103 ± 0.49
1.802ArgHis: 1.802 ± 0.926
3.004ArgIle: 3.004 ± 0.362
4.806ArgLys: 4.806 ± 1.288
4.506ArgLeu: 4.506 ± 1.822
1.802ArgMet: 1.802 ± 0.335
2.103ArgAsn: 2.103 ± 0.49
1.502ArgPro: 1.502 ± 0.772
1.802ArgGln: 1.802 ± 0.335
2.103ArgArg: 2.103 ± 0.49
2.403ArgSer: 2.403 ± 0.053
3.605ArgThr: 3.605 ± 0.079
3.004ArgVal: 3.004 ± 0.229
0.601ArgTrp: 0.601 ± 0.309
2.704ArgTyr: 2.704 ± 0.207
0.0ArgXaa: 0.0 ± 0.0
Ser
5.407SerAla: 5.407 ± 0.768
1.502SerCys: 1.502 ± 0.181
4.806SerAsp: 4.806 ± 1.077
4.205SerGlu: 4.205 ± 0.203
3.004SerPhe: 3.004 ± 0.953
5.407SerGly: 5.407 ± 0.177
2.103SerHis: 2.103 ± 1.081
3.605SerIle: 3.605 ± 0.079
3.605SerLys: 3.605 ± 0.512
5.407SerLeu: 5.407 ± 0.177
1.802SerMet: 1.802 ± 0.256
3.605SerAsn: 3.605 ± 1.694
2.704SerPro: 2.704 ± 0.384
3.304SerGln: 3.304 ± 1.257
3.304SerArg: 3.304 ± 0.516
5.707SerSer: 5.707 ± 0.613
4.806SerThr: 4.806 ± 0.106
5.107SerVal: 5.107 ± 0.922
0.901SerTrp: 0.901 ± 0.128
3.304SerTyr: 3.304 ± 0.516
0.0SerXaa: 0.0 ± 0.0
Thr
4.205ThrAla: 4.205 ± 3.159
0.901ThrCys: 0.901 ± 0.463
4.205ThrAsp: 4.205 ± 0.979
3.004ThrGlu: 3.004 ± 0.229
2.704ThrPhe: 2.704 ± 1.39
4.806ThrGly: 4.806 ± 1.668
1.502ThrHis: 1.502 ± 0.41
3.605ThrIle: 3.605 ± 1.694
3.605ThrLys: 3.605 ± 0.671
4.205ThrLeu: 4.205 ± 0.794
1.802ThrMet: 1.802 ± 0.926
3.304ThrAsn: 3.304 ± 0.666
4.506ThrPro: 4.506 ± 1.822
1.802ThrGln: 1.802 ± 0.335
3.004ThrArg: 3.004 ± 0.229
3.605ThrSer: 3.605 ± 0.671
5.707ThrThr: 5.707 ± 1.16
3.905ThrVal: 3.905 ± 2.007
0.601ThrTrp: 0.601 ± 0.309
1.502ThrTyr: 1.502 ± 0.181
0.0ThrXaa: 0.0 ± 0.0
Val
4.205ValAla: 4.205 ± 0.388
0.901ValCys: 0.901 ± 0.128
2.704ValAsp: 2.704 ± 0.207
3.905ValGlu: 3.905 ± 0.949
6.008ValPhe: 6.008 ± 0.724
3.004ValGly: 3.004 ± 0.821
2.103ValHis: 2.103 ± 0.49
3.304ValIle: 3.304 ± 2.44
4.205ValLys: 4.205 ± 0.979
6.308ValLeu: 6.308 ± 1.469
0.601ValMet: 0.601 ± 0.282
1.502ValAsn: 1.502 ± 0.181
3.905ValPro: 3.905 ± 0.825
2.704ValGln: 2.704 ± 0.975
3.304ValArg: 3.304 ± 1.107
5.407ValSer: 5.407 ± 3.724
4.205ValThr: 4.205 ± 2.568
4.806ValVal: 4.806 ± 2.85
0.901ValTrp: 0.901 ± 0.128
3.304ValTyr: 3.304 ± 1.107
0.0ValXaa: 0.0 ± 0.0
Trp
0.3TrpAla: 0.3 ± 0.154
0.601TrpCys: 0.601 ± 0.309
0.901TrpAsp: 0.901 ± 0.128
0.3TrpGlu: 0.3 ± 0.154
0.601TrpPhe: 0.601 ± 0.309
0.601TrpGly: 0.601 ± 0.309
0.0TrpHis: 0.0 ± 0.0
0.601TrpIle: 0.601 ± 0.309
1.202TrpLys: 1.202 ± 0.026
1.202TrpLeu: 1.202 ± 0.026
0.901TrpMet: 0.901 ± 0.719
0.901TrpAsn: 0.901 ± 0.463
0.0TrpPro: 0.0 ± 0.0
0.901TrpGln: 0.901 ± 1.31
1.202TrpArg: 1.202 ± 0.618
0.3TrpSer: 0.3 ± 0.154
2.403TrpThr: 2.403 ± 0.053
0.901TrpVal: 0.901 ± 0.128
0.0TrpTrp: 0.0 ± 0.0
1.202TrpTyr: 1.202 ± 0.618
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.605TyrAla: 3.605 ± 0.671
0.901TyrCys: 0.901 ± 0.463
2.103TyrAsp: 2.103 ± 0.101
1.802TyrGlu: 1.802 ± 0.926
2.103TyrPhe: 2.103 ± 0.49
1.202TyrGly: 1.202 ± 0.618
1.802TyrHis: 1.802 ± 0.256
0.901TyrIle: 0.901 ± 0.128
2.403TyrLys: 2.403 ± 0.538
3.004TyrLeu: 3.004 ± 0.362
0.3TyrMet: 0.3 ± 0.154
1.202TyrAsn: 1.202 ± 0.026
1.202TyrPro: 1.202 ± 0.026
1.802TyrGln: 1.802 ± 0.926
1.802TyrArg: 1.802 ± 0.256
2.403TyrSer: 2.403 ± 0.053
2.403TyrThr: 2.403 ± 0.644
2.403TyrVal: 2.403 ± 0.053
0.901TyrTrp: 0.901 ± 0.463
1.202TyrTyr: 1.202 ± 0.618
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (3330 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski