Amino acid dipepetide frequency for Pseudomonas guangdongensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.594AlaAla: 17.594 ± 0.199	1.555AlaCys: 1.555 ± 0.043	6.296AlaAsp: 6.296 ± 0.08	8.896AlaGlu: 8.896 ± 0.12	3.827AlaPhe: 3.827 ± 0.069	10.938AlaGly: 10.938 ± 0.137	2.435AlaHis: 2.435 ± 0.057	5.122AlaIle: 5.122 ± 0.079	2.959AlaLys: 2.959 ± 0.072	16.98AlaLeu: 16.98 ± 0.204	2.873AlaMet: 2.873 ± 0.063	2.473AlaAsn: 2.473 ± 0.054	5.852AlaPro: 5.852 ± 0.096	5.673AlaGln: 5.673 ± 0.087	9.928AlaArg: 9.928 ± 0.133	6.285AlaSer: 6.285 ± 0.098	4.563AlaThr: 4.563 ± 0.078	8.047AlaVal: 8.047 ± 0.104	1.866AlaTrp: 1.866 ± 0.053	2.333AlaTyr: 2.333 ± 0.054	0.0AlaXaa: 0.0 ± 0.0
Cys	1.438CysAla: 1.438 ± 0.04	0.149CysCys: 0.149 ± 0.014	0.575CysAsp: 0.575 ± 0.022	0.574CysGlu: 0.574 ± 0.021	0.315CysPhe: 0.315 ± 0.019	1.095CysGly: 1.095 ± 0.038	0.292CysHis: 0.292 ± 0.018	0.419CysIle: 0.419 ± 0.023	0.258CysLys: 0.258 ± 0.018	1.192CysLeu: 1.192 ± 0.039	0.194CysMet: 0.194 ± 0.015	0.251CysAsn: 0.251 ± 0.016	0.548CysPro: 0.548 ± 0.027	0.42CysGln: 0.42 ± 0.022	0.864CysArg: 0.864 ± 0.033	0.624CysSer: 0.624 ± 0.031	0.431CysThr: 0.431 ± 0.019	0.708CysVal: 0.708 ± 0.031	0.158CysTrp: 0.158 ± 0.014	0.251CysTyr: 0.251 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	6.57AspAla: 6.57 ± 0.08	0.618AspCys: 0.618 ± 0.026	2.736AspAsp: 2.736 ± 0.065	3.566AspGlu: 3.566 ± 0.062	2.037AspPhe: 2.037 ± 0.042	4.886AspGly: 4.886 ± 0.075	1.078AspHis: 1.078 ± 0.044	2.387AspIle: 2.387 ± 0.052	1.699AspLys: 1.699 ± 0.047	6.017AspLeu: 6.017 ± 0.092	1.104AspMet: 1.104 ± 0.038	1.547AspAsn: 1.547 ± 0.045	2.756AspPro: 2.756 ± 0.054	1.589AspGln: 1.589 ± 0.04	3.164AspArg: 3.164 ± 0.07	2.904AspSer: 2.904 ± 0.06	2.154AspThr: 2.154 ± 0.048	3.072AspVal: 3.072 ± 0.059	1.04AspTrp: 1.04 ± 0.037	1.698AspTyr: 1.698 ± 0.046	0.0AspXaa: 0.0 ± 0.0
Glu	7.871GluAla: 7.871 ± 0.107	0.48GluCys: 0.48 ± 0.024	2.619GluAsp: 2.619 ± 0.049	3.555GluGlu: 3.555 ± 0.096	1.864GluPhe: 1.864 ± 0.051	4.273GluGly: 4.273 ± 0.079	1.631GluHis: 1.631 ± 0.042	2.857GluIle: 2.857 ± 0.064	1.813GluLys: 1.813 ± 0.051	8.094GluLeu: 8.094 ± 0.112	1.214GluMet: 1.214 ± 0.038	1.23GluAsn: 1.23 ± 0.036	2.624GluPro: 2.624 ± 0.058	3.964GluGln: 3.964 ± 0.07	6.228GluArg: 6.228 ± 0.091	2.456GluSer: 2.456 ± 0.049	2.296GluThr: 2.296 ± 0.052	4.509GluVal: 4.509 ± 0.073	0.743GluTrp: 0.743 ± 0.029	1.158GluTyr: 1.158 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	4.597PheAla: 4.597 ± 0.088	0.419PheCys: 0.419 ± 0.02	2.365PheAsp: 2.365 ± 0.047	2.025PheGlu: 2.025 ± 0.045	1.288PhePhe: 1.288 ± 0.041	3.081PheGly: 3.081 ± 0.067	0.724PheHis: 0.724 ± 0.028	1.384PheIle: 1.384 ± 0.041	0.943PheLys: 0.943 ± 0.034	3.177PheLeu: 3.177 ± 0.059	0.695PheMet: 0.695 ± 0.03	1.024PheAsn: 1.024 ± 0.028	1.352PhePro: 1.352 ± 0.032	1.055PheGln: 1.055 ± 0.034	1.953PheArg: 1.953 ± 0.047	2.024PheSer: 2.024 ± 0.048	1.477PheThr: 1.477 ± 0.046	2.552PheVal: 2.552 ± 0.053	0.498PheTrp: 0.498 ± 0.028	0.894PheTyr: 0.894 ± 0.029	0.0PheXaa: 0.0 ± 0.0
Gly	8.842GlyAla: 8.842 ± 0.097	1.038GlyCys: 1.038 ± 0.039	4.039GlyAsp: 4.039 ± 0.074	5.891GlyGlu: 5.891 ± 0.093	3.125GlyPhe: 3.125 ± 0.06	6.568GlyGly: 6.568 ± 0.092	1.995GlyHis: 1.995 ± 0.051	3.969GlyIle: 3.969 ± 0.069	2.992GlyLys: 2.992 ± 0.058	10.016GlyLeu: 10.016 ± 0.128	2.149GlyMet: 2.149 ± 0.045	2.224GlyAsn: 2.224 ± 0.055	2.527GlyPro: 2.527 ± 0.056	3.639GlyGln: 3.639 ± 0.06	6.116GlyArg: 6.116 ± 0.074	4.528GlySer: 4.528 ± 0.078	3.404GlyThr: 3.404 ± 0.071	5.939GlyVal: 5.939 ± 0.093	1.376GlyTrp: 1.376 ± 0.039	2.339GlyTyr: 2.339 ± 0.058	0.0GlyXaa: 0.0 ± 0.0
His	2.654HisAla: 2.654 ± 0.06	0.383HisCys: 0.383 ± 0.019	1.274HisAsp: 1.274 ± 0.043	1.192HisGlu: 1.192 ± 0.042	0.944HisPhe: 0.944 ± 0.038	2.25HisGly: 2.25 ± 0.055	0.587HisHis: 0.587 ± 0.027	0.896HisIle: 0.896 ± 0.029	0.59HisLys: 0.59 ± 0.025	2.742HisLeu: 2.742 ± 0.06	0.492HisMet: 0.492 ± 0.024	0.621HisAsn: 0.621 ± 0.026	1.48HisPro: 1.48 ± 0.038	0.824HisGln: 0.824 ± 0.031	1.466HisArg: 1.466 ± 0.038	1.171HisSer: 1.171 ± 0.041	0.938HisThr: 0.938 ± 0.031	1.273HisVal: 1.273 ± 0.036	0.487HisTrp: 0.487 ± 0.024	0.725HisTyr: 0.725 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	5.764IleAla: 5.764 ± 0.084	0.424IleCys: 0.424 ± 0.02	3.143IleAsp: 3.143 ± 0.064	3.166IleGlu: 3.166 ± 0.068	1.187IlePhe: 1.187 ± 0.042	4.093IleGly: 4.093 ± 0.08	0.988IleHis: 0.988 ± 0.033	1.411IleIle: 1.411 ± 0.045	1.36IleLys: 1.36 ± 0.038	3.953IleLeu: 3.953 ± 0.069	0.705IleMet: 0.705 ± 0.031	1.367IleAsn: 1.367 ± 0.04	2.027IlePro: 2.027 ± 0.048	1.341IleGln: 1.341 ± 0.04	3.011IleArg: 3.011 ± 0.052	2.139IleSer: 2.139 ± 0.049	1.916IleThr: 1.916 ± 0.05	3.105IleVal: 3.105 ± 0.064	0.365IleTrp: 0.365 ± 0.017	0.865IleTyr: 0.865 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	3.469LysAla: 3.469 ± 0.076	0.167LysCys: 0.167 ± 0.014	1.415LysAsp: 1.415 ± 0.046	1.364LysGlu: 1.364 ± 0.046	0.724LysPhe: 0.724 ± 0.036	2.189LysGly: 2.189 ± 0.056	0.646LysHis: 0.646 ± 0.026	1.327LysIle: 1.327 ± 0.043	1.114LysLys: 1.114 ± 0.039	3.165LysLeu: 3.165 ± 0.068	0.575LysMet: 0.575 ± 0.027	0.758LysAsn: 0.758 ± 0.031	1.651LysPro: 1.651 ± 0.044	1.215LysGln: 1.215 ± 0.035	2.061LysArg: 2.061 ± 0.053	1.522LysSer: 1.522 ± 0.039	1.479LysThr: 1.479 ± 0.043	2.301LysVal: 2.301 ± 0.057	0.274LysTrp: 0.274 ± 0.015	0.565LysTyr: 0.565 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	17.919LeuAla: 17.919 ± 0.19	1.386LeuCys: 1.386 ± 0.033	7.842LeuAsp: 7.842 ± 0.102	7.199LeuGlu: 7.199 ± 0.1	4.005LeuPhe: 4.005 ± 0.09	10.48LeuGly: 10.48 ± 0.132	2.702LeuHis: 2.702 ± 0.059	5.062LeuIle: 5.062 ± 0.081	3.767LeuLys: 3.767 ± 0.063	16.502LeuLeu: 16.502 ± 0.239	2.211LeuMet: 2.211 ± 0.046	3.17LeuAsn: 3.17 ± 0.06	7.199LeuPro: 7.199 ± 0.1	5.286LeuGln: 5.286 ± 0.101	9.19LeuArg: 9.19 ± 0.138	6.488LeuSer: 6.488 ± 0.088	4.914LeuThr: 4.914 ± 0.077	7.859LeuVal: 7.859 ± 0.102	1.613LeuTrp: 1.613 ± 0.05	2.562LeuTyr: 2.562 ± 0.056	0.0LeuXaa: 0.0 ± 0.0
Met	2.433MetAla: 2.433 ± 0.058	0.166MetCys: 0.166 ± 0.014	0.981MetAsp: 0.981 ± 0.032	0.891MetGlu: 0.891 ± 0.03	0.509MetPhe: 0.509 ± 0.023	1.533MetGly: 1.533 ± 0.039	0.529MetHis: 0.529 ± 0.024	0.896MetIle: 0.896 ± 0.035	0.714MetLys: 0.714 ± 0.029	2.487MetLeu: 2.487 ± 0.05	0.384MetMet: 0.384 ± 0.021	0.695MetAsn: 0.695 ± 0.031	1.244MetPro: 1.244 ± 0.036	0.988MetGln: 0.988 ± 0.038	1.511MetArg: 1.511 ± 0.042	1.628MetSer: 1.628 ± 0.04	1.169MetThr: 1.169 ± 0.04	1.326MetVal: 1.326 ± 0.045	0.142MetTrp: 0.142 ± 0.012	0.327MetTyr: 0.327 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	2.895AsnAla: 2.895 ± 0.067	0.23AsnCys: 0.23 ± 0.016	1.243AsnAsp: 1.243 ± 0.041	1.164AsnGlu: 1.164 ± 0.033	0.901AsnPhe: 0.901 ± 0.028	2.117AsnGly: 2.117 ± 0.054	0.528AsnHis: 0.528 ± 0.023	1.17AsnIle: 1.17 ± 0.041	0.694AsnLys: 0.694 ± 0.031	3.061AsnLeu: 3.061 ± 0.063	0.482AsnMet: 0.482 ± 0.024	0.638AsnAsn: 0.638 ± 0.028	1.859AsnPro: 1.859 ± 0.044	0.949AsnGln: 0.949 ± 0.033	1.846AsnArg: 1.846 ± 0.044	1.17AsnSer: 1.17 ± 0.042	1.086AsnThr: 1.086 ± 0.038	1.613AsnVal: 1.613 ± 0.051	0.339AsnTrp: 0.339 ± 0.019	0.628AsnTyr: 0.628 ± 0.028	0.0AsnXaa: 0.0 ± 0.0
Pro	7.143ProAla: 7.143 ± 0.114	0.482ProCys: 0.482 ± 0.026	2.663ProAsp: 2.663 ± 0.061	3.415ProGlu: 3.415 ± 0.061	1.693ProPhe: 1.693 ± 0.047	4.222ProGly: 4.222 ± 0.071	1.16ProHis: 1.16 ± 0.033	1.666ProIle: 1.666 ± 0.049	1.137ProLys: 1.137 ± 0.033	6.495ProLeu: 6.495 ± 0.1	1.02ProMet: 1.02 ± 0.031	1.093ProAsn: 1.093 ± 0.04	2.322ProPro: 2.322 ± 0.06	2.518ProGln: 2.518 ± 0.054	3.294ProArg: 3.294 ± 0.068	2.282ProSer: 2.282 ± 0.053	1.825ProThr: 1.825 ± 0.041	3.613ProVal: 3.613 ± 0.058	0.785ProTrp: 0.785 ± 0.03	1.039ProTyr: 1.039 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	6.323GlnAla: 6.323 ± 0.099	0.328GlnCys: 0.328 ± 0.016	1.669GlnAsp: 1.669 ± 0.045	1.901GlnGlu: 1.901 ± 0.052	1.249GlnPhe: 1.249 ± 0.039	3.366GlnGly: 3.366 ± 0.061	1.08GlnHis: 1.08 ± 0.034	1.864GlnIle: 1.864 ± 0.046	0.988GlnLys: 0.988 ± 0.037	5.805GlnLeu: 5.805 ± 0.114	0.951GlnMet: 0.951 ± 0.031	0.891GlnAsn: 0.891 ± 0.032	2.496GlnPro: 2.496 ± 0.052	2.626GlnGln: 2.626 ± 0.076	4.355GlnArg: 4.355 ± 0.095	1.909GlnSer: 1.909 ± 0.044	1.741GlnThr: 1.741 ± 0.046	3.384GlnVal: 3.384 ± 0.06	0.6GlnTrp: 0.6 ± 0.026	0.81GlnTyr: 0.81 ± 0.037	0.0GlnXaa: 0.0 ± 0.0
Arg	8.202ArgAla: 8.202 ± 0.095	0.76ArgCys: 0.76 ± 0.028	3.808ArgAsp: 3.808 ± 0.07	5.393ArgGlu: 5.393 ± 0.086	2.91ArgPhe: 2.91 ± 0.059	5.008ArgGly: 5.008 ± 0.088	2.256ArgHis: 2.256 ± 0.046	3.619ArgIle: 3.619 ± 0.07	1.876ArgLys: 1.876 ± 0.052	10.877ArgLeu: 10.877 ± 0.158	1.664ArgMet: 1.664 ± 0.042	1.731ArgAsn: 1.731 ± 0.041	3.475ArgPro: 3.475 ± 0.069	4.129ArgGln: 4.129 ± 0.088	5.946ArgArg: 5.946 ± 0.096	3.643ArgSer: 3.643 ± 0.065	2.549ArgThr: 2.549 ± 0.049	4.874ArgVal: 4.874 ± 0.077	1.205ArgTrp: 1.205 ± 0.037	2.046ArgTyr: 2.046 ± 0.052	0.0ArgXaa: 0.0 ± 0.0
Ser	6.129SerAla: 6.129 ± 0.081	0.499SerCys: 0.499 ± 0.025	2.479SerAsp: 2.479 ± 0.056	2.81SerGlu: 2.81 ± 0.058	1.804SerPhe: 1.804 ± 0.043	5.041SerGly: 5.041 ± 0.094	1.218SerHis: 1.218 ± 0.037	2.157SerIle: 2.157 ± 0.055	1.298SerLys: 1.298 ± 0.041	6.93SerLeu: 6.93 ± 0.091	1.059SerMet: 1.059 ± 0.038	1.269SerAsn: 1.269 ± 0.043	2.379SerPro: 2.379 ± 0.051	1.956SerGln: 1.956 ± 0.049	3.74SerArg: 3.74 ± 0.064	2.721SerSer: 2.721 ± 0.063	2.201SerThr: 2.201 ± 0.046	3.454SerVal: 3.454 ± 0.077	0.653SerTrp: 0.653 ± 0.025	1.223SerTyr: 1.223 ± 0.039	0.0SerXaa: 0.0 ± 0.0
Thr	4.644ThrAla: 4.644 ± 0.077	0.441ThrCys: 0.441 ± 0.023	1.875ThrAsp: 1.875 ± 0.043	1.951ThrGlu: 1.951 ± 0.048	1.455ThrPhe: 1.455 ± 0.041	3.641ThrGly: 3.641 ± 0.079	0.871ThrHis: 0.871 ± 0.029	1.489ThrIle: 1.489 ± 0.042	0.825ThrLys: 0.825 ± 0.029	6.197ThrLeu: 6.197 ± 0.103	0.666ThrMet: 0.666 ± 0.028	0.835ThrAsn: 0.835 ± 0.032	2.935ThrPro: 2.935 ± 0.067	1.459ThrGln: 1.459 ± 0.047	3.041ThrArg: 3.041 ± 0.057	1.987ThrSer: 1.987 ± 0.054	1.802ThrThr: 1.802 ± 0.057	2.969ThrVal: 2.969 ± 0.06	0.511ThrTrp: 0.511 ± 0.023	0.94ThrTyr: 0.94 ± 0.039	0.0ThrXaa: 0.0 ± 0.0
Val	8.156ValAla: 8.156 ± 0.117	0.774ValCys: 0.774 ± 0.029	3.863ValAsp: 3.863 ± 0.072	4.946ValGlu: 4.946 ± 0.073	2.356ValPhe: 2.356 ± 0.048	5.144ValGly: 5.144 ± 0.077	1.364ValHis: 1.364 ± 0.042	3.277ValIle: 3.277 ± 0.067	1.96ValLys: 1.96 ± 0.049	8.29ValLeu: 8.29 ± 0.099	1.408ValMet: 1.408 ± 0.037	1.864ValAsn: 1.864 ± 0.048	3.161ValPro: 3.161 ± 0.066	2.607ValGln: 2.607 ± 0.054	4.789ValArg: 4.789 ± 0.072	3.544ValSer: 3.544 ± 0.08	3.079ValThr: 3.079 ± 0.061	5.126ValVal: 5.126 ± 0.091	0.813ValTrp: 0.813 ± 0.027	1.459ValTyr: 1.459 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	1.192TrpAla: 1.192 ± 0.039	0.183TrpCys: 0.183 ± 0.014	0.589TrpAsp: 0.589 ± 0.028	0.532TrpGlu: 0.532 ± 0.023	0.482TrpPhe: 0.482 ± 0.021	0.876TrpGly: 0.876 ± 0.032	0.402TrpHis: 0.402 ± 0.021	0.515TrpIle: 0.515 ± 0.023	0.383TrpLys: 0.383 ± 0.021	2.512TrpLeu: 2.512 ± 0.062	0.327TrpMet: 0.327 ± 0.018	0.365TrpAsn: 0.365 ± 0.019	0.732TrpPro: 0.732 ± 0.032	1.042TrpGln: 1.042 ± 0.037	1.265TrpArg: 1.265 ± 0.042	0.749TrpSer: 0.749 ± 0.026	0.522TrpThr: 0.522 ± 0.025	0.83TrpVal: 0.83 ± 0.03	0.244TrpTrp: 0.244 ± 0.018	0.329TrpTyr: 0.329 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.662TyrAla: 2.662 ± 0.057	0.273TyrCys: 0.273 ± 0.019	1.147TyrAsp: 1.147 ± 0.037	1.049TyrGlu: 1.049 ± 0.037	0.849TyrPhe: 0.849 ± 0.023	1.914TyrGly: 1.914 ± 0.046	0.502TyrHis: 0.502 ± 0.023	0.843TyrIle: 0.843 ± 0.029	0.611TyrLys: 0.611 ± 0.026	2.863TyrLeu: 2.863 ± 0.058	0.377TyrMet: 0.377 ± 0.022	0.568TyrAsn: 0.568 ± 0.024	1.248TyrPro: 1.248 ± 0.033	1.057TyrGln: 1.057 ± 0.037	2.204TyrArg: 2.204 ± 0.058	1.245TyrSer: 1.245 ± 0.04	0.988TyrThr: 0.988 ± 0.032	1.429TyrVal: 1.429 ± 0.04	0.362TyrTrp: 0.362 ± 0.02	0.619TyrTyr: 0.619 ± 0.027	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2871 proteins (945301 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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