Amino acid dipepetide frequency for Tortoise microvirus 25

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.133AlaAla: 7.133 ± 4.087
0.0AlaCys: 0.0 ± 0.0
4.28AlaAsp: 4.28 ± 2.078
5.706AlaGlu: 5.706 ± 1.5
0.713AlaPhe: 0.713 ± 0.738
8.559AlaGly: 8.559 ± 1.654
4.28AlaHis: 4.28 ± 1.938
7.133AlaIle: 7.133 ± 1.553
2.14AlaLys: 2.14 ± 1.594
3.566AlaLeu: 3.566 ± 1.033
0.0AlaMet: 0.0 ± 0.0
2.853AlaAsn: 2.853 ± 1.432
5.706AlaPro: 5.706 ± 1.561
3.566AlaGln: 3.566 ± 2.432
3.566AlaArg: 3.566 ± 1.198
3.566AlaSer: 3.566 ± 1.152
2.853AlaThr: 2.853 ± 1.084
4.993AlaVal: 4.993 ± 1.104
0.713AlaTrp: 0.713 ± 0.508
2.853AlaTyr: 2.853 ± 1.084
0.0AlaXaa: 0.0 ± 0.0
Cys
1.427CysAla: 1.427 ± 0.542
0.0CysCys: 0.0 ± 0.0
2.14CysAsp: 2.14 ± 1.098
0.713CysGlu: 0.713 ± 0.738
0.713CysPhe: 0.713 ± 0.738
0.713CysGly: 0.713 ± 0.738
0.0CysHis: 0.0 ± 0.0
0.713CysIle: 0.713 ± 0.508
0.0CysLys: 0.0 ± 0.0
0.713CysLeu: 0.713 ± 0.738
0.0CysMet: 0.0 ± 0.0
1.427CysAsn: 1.427 ± 1.12
1.427CysPro: 1.427 ± 1.476
0.0CysGln: 0.0 ± 0.0
2.14CysArg: 2.14 ± 2.214
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.713CysVal: 0.713 ± 0.508
0.0CysTrp: 0.0 ± 0.0
0.713CysTyr: 0.713 ± 0.738
0.0CysXaa: 0.0 ± 0.0
Asp
2.14AspAla: 2.14 ± 1.824
0.0AspCys: 0.0 ± 0.0
4.28AspAsp: 4.28 ± 3.929
5.706AspGlu: 5.706 ± 3.857
2.853AspPhe: 2.853 ± 0.998
1.427AspGly: 1.427 ± 1.015
0.713AspHis: 0.713 ± 0.508
2.853AspIle: 2.853 ± 0.998
2.853AspLys: 2.853 ± 0.807
4.993AspLeu: 4.993 ± 1.669
3.566AspMet: 3.566 ± 1.623
3.566AspAsn: 3.566 ± 3.641
3.566AspPro: 3.566 ± 2.47
2.853AspGln: 2.853 ± 0.635
3.566AspArg: 3.566 ± 0.952
1.427AspSer: 1.427 ± 0.893
2.853AspThr: 2.853 ± 1.809
4.28AspVal: 4.28 ± 3.07
0.0AspTrp: 0.0 ± 0.0
2.853AspTyr: 2.853 ± 1.022
0.0AspXaa: 0.0 ± 0.0
Glu
4.28GluAla: 4.28 ± 2.529
2.14GluCys: 2.14 ± 1.098
0.713GluAsp: 0.713 ± 0.951
2.14GluGlu: 2.14 ± 2.066
4.993GluPhe: 4.993 ± 2.04
2.853GluGly: 2.853 ± 1.918
0.713GluHis: 0.713 ± 0.641
3.566GluIle: 3.566 ± 1.834
1.427GluLys: 1.427 ± 1.476
2.14GluLeu: 2.14 ± 1.191
3.566GluMet: 3.566 ± 1.591
1.427GluAsn: 1.427 ± 0.664
0.713GluPro: 0.713 ± 0.508
4.993GluGln: 4.993 ± 2.031
2.853GluArg: 2.853 ± 1.809
4.28GluSer: 4.28 ± 1.938
4.993GluThr: 4.993 ± 2.362
4.28GluVal: 4.28 ± 0.717
2.14GluTrp: 2.14 ± 2.214
4.28GluTyr: 4.28 ± 0.976
0.0GluXaa: 0.0 ± 0.0
Phe
1.427PheAla: 1.427 ± 1.476
0.713PheCys: 0.713 ± 0.738
2.14PheAsp: 2.14 ± 1.094
0.713PheGlu: 0.713 ± 0.508
1.427PhePhe: 1.427 ± 1.12
6.419PheGly: 6.419 ± 2.242
0.713PheHis: 0.713 ± 0.641
2.853PheIle: 2.853 ± 0.635
0.0PheLys: 0.0 ± 0.0
2.14PheLeu: 2.14 ± 1.28
1.427PheMet: 1.427 ± 0.57
2.14PheAsn: 2.14 ± 1.523
0.713PhePro: 0.713 ± 0.508
0.0PheGln: 0.0 ± 0.0
2.14PheArg: 2.14 ± 0.747
2.14PheSer: 2.14 ± 2.24
3.566PheThr: 3.566 ± 1.989
1.427PheVal: 1.427 ± 0.542
0.0PheTrp: 0.0 ± 0.0
0.713PheTyr: 0.713 ± 0.508
0.0PheXaa: 0.0 ± 0.0
Gly
5.706GlyAla: 5.706 ± 1.904
2.853GlyCys: 2.853 ± 1.906
3.566GlyAsp: 3.566 ± 1.989
3.566GlyGlu: 3.566 ± 1.865
0.713GlyPhe: 0.713 ± 0.508
4.993GlyGly: 4.993 ± 1.496
2.14GlyHis: 2.14 ± 0.604
5.706GlyIle: 5.706 ± 1.269
2.853GlyLys: 2.853 ± 2.23
5.706GlyLeu: 5.706 ± 1.896
2.14GlyMet: 2.14 ± 1.4
2.14GlyAsn: 2.14 ± 1.08
0.0GlyPro: 0.0 ± 0.0
4.993GlyGln: 4.993 ± 2.886
2.853GlyArg: 2.853 ± 1.752
4.993GlySer: 4.993 ± 2.277
4.993GlyThr: 4.993 ± 1.449
3.566GlyVal: 3.566 ± 1.246
0.0GlyTrp: 0.0 ± 0.0
4.993GlyTyr: 4.993 ± 2.005
0.0GlyXaa: 0.0 ± 0.0
His
1.427HisAla: 1.427 ± 1.281
0.713HisCys: 0.713 ± 0.738
2.14HisAsp: 2.14 ± 1.098
2.14HisGlu: 2.14 ± 0.604
1.427HisPhe: 1.427 ± 1.015
2.14HisGly: 2.14 ± 0.604
0.0HisHis: 0.0 ± 0.0
1.427HisIle: 1.427 ± 0.918
1.427HisLys: 1.427 ± 0.918
1.427HisLeu: 1.427 ± 0.542
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.713HisPro: 0.713 ± 0.641
1.427HisGln: 1.427 ± 1.281
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
0.713HisThr: 0.713 ± 0.508
1.427HisVal: 1.427 ± 0.664
0.0HisTrp: 0.0 ± 0.0
2.14HisTyr: 2.14 ± 1.08
0.0HisXaa: 0.0 ± 0.0
Ile
4.993IleAla: 4.993 ± 2.258
1.427IleCys: 1.427 ± 1.476
3.566IleAsp: 3.566 ± 1.283
2.853IleGlu: 2.853 ± 1.121
0.0IlePhe: 0.0 ± 0.0
4.993IleGly: 4.993 ± 1.521
1.427IleHis: 1.427 ± 0.542
3.566IleIle: 3.566 ± 1.033
1.427IleLys: 1.427 ± 1.344
4.28IleLeu: 4.28 ± 2.774
2.14IleMet: 2.14 ± 0.721
4.28IleAsn: 4.28 ± 2.108
4.993IlePro: 4.993 ± 1.709
1.427IleGln: 1.427 ± 1.12
4.28IleArg: 4.28 ± 2.345
3.566IleSer: 3.566 ± 1.203
2.853IleThr: 2.853 ± 1.174
1.427IleVal: 1.427 ± 0.664
0.0IleTrp: 0.0 ± 0.0
3.566IleTyr: 3.566 ± 1.203
0.0IleXaa: 0.0 ± 0.0
Lys
2.14LysAla: 2.14 ± 1.537
0.0LysCys: 0.0 ± 0.0
1.427LysAsp: 1.427 ± 0.542
3.566LysGlu: 3.566 ± 1.984
1.427LysPhe: 1.427 ± 0.542
3.566LysGly: 3.566 ± 0.978
0.713LysHis: 0.713 ± 0.508
2.14LysIle: 2.14 ± 2.214
2.853LysLys: 2.853 ± 2.23
2.853LysLeu: 2.853 ± 2.432
0.713LysMet: 0.713 ± 0.641
3.566LysAsn: 3.566 ± 0.804
1.427LysPro: 1.427 ± 0.542
0.713LysGln: 0.713 ± 1.176
4.993LysArg: 4.993 ± 2.688
1.427LysSer: 1.427 ± 0.918
1.427LysThr: 1.427 ± 0.542
3.566LysVal: 3.566 ± 1.355
0.713LysTrp: 0.713 ± 0.508
1.427LysTyr: 1.427 ± 1.004
0.0LysXaa: 0.0 ± 0.0
Leu
2.14LeuAla: 2.14 ± 1.202
0.713LeuCys: 0.713 ± 1.176
4.993LeuAsp: 4.993 ± 3.986
5.706LeuGlu: 5.706 ± 1.614
4.28LeuPhe: 4.28 ± 1.192
2.853LeuGly: 2.853 ± 1.174
2.14LeuHis: 2.14 ± 1.364
3.566LeuIle: 3.566 ± 1.203
2.853LeuLys: 2.853 ± 1.121
4.993LeuLeu: 4.993 ± 1.629
0.713LeuMet: 0.713 ± 0.508
2.14LeuAsn: 2.14 ± 0.994
3.566LeuPro: 3.566 ± 0.978
2.853LeuGln: 2.853 ± 2.031
9.272LeuArg: 9.272 ± 1.086
7.846LeuSer: 7.846 ± 4.118
2.14LeuThr: 2.14 ± 1.537
2.14LeuVal: 2.14 ± 0.994
1.427LeuTrp: 1.427 ± 1.015
0.713LeuTyr: 0.713 ± 0.738
0.0LeuXaa: 0.0 ± 0.0
Met
1.427MetAla: 1.427 ± 1.281
1.427MetCys: 1.427 ± 0.542
2.14MetAsp: 2.14 ± 1.39
0.0MetGlu: 0.0 ± 0.0
1.427MetPhe: 1.427 ± 0.542
1.427MetGly: 1.427 ± 0.664
1.427MetHis: 1.427 ± 0.664
0.713MetIle: 0.713 ± 1.176
0.0MetLys: 0.0 ± 0.0
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
2.853MetPro: 2.853 ± 1.432
3.566MetGln: 3.566 ± 1.468
4.993MetArg: 4.993 ± 0.75
2.853MetSer: 2.853 ± 0.887
2.14MetThr: 2.14 ± 1.098
2.14MetVal: 2.14 ± 1.523
0.0MetTrp: 0.0 ± 0.0
2.853MetTyr: 2.853 ± 2.212
0.0MetXaa: 0.0 ± 0.0
Asn
2.853AsnAla: 2.853 ± 0.925
0.0AsnCys: 0.0 ± 0.0
2.14AsnAsp: 2.14 ± 2.24
2.853AsnGlu: 2.853 ± 1.157
1.427AsnPhe: 1.427 ± 1.015
2.853AsnGly: 2.853 ± 1.473
0.0AsnHis: 0.0 ± 0.0
1.427AsnIle: 1.427 ± 1.281
2.14AsnLys: 2.14 ± 0.747
6.419AsnLeu: 6.419 ± 1.99
2.14AsnMet: 2.14 ± 1.08
1.427AsnAsn: 1.427 ± 1.12
2.853AsnPro: 2.853 ± 1.157
2.14AsnGln: 2.14 ± 0.821
6.419AsnArg: 6.419 ± 2.339
0.713AsnSer: 0.713 ± 0.508
1.427AsnThr: 1.427 ± 0.893
5.706AsnVal: 5.706 ± 2.759
0.713AsnTrp: 0.713 ± 0.641
0.713AsnTyr: 0.713 ± 0.641
0.0AsnXaa: 0.0 ± 0.0
Pro
4.28ProAla: 4.28 ± 0.717
0.0ProCys: 0.0 ± 0.0
1.427ProAsp: 1.427 ± 1.12
2.853ProGlu: 2.853 ± 0.635
1.427ProPhe: 1.427 ± 1.015
4.993ProGly: 4.993 ± 1.23
0.713ProHis: 0.713 ± 0.951
3.566ProIle: 3.566 ± 1.905
2.853ProLys: 2.853 ± 1.648
5.706ProLeu: 5.706 ± 2.187
3.566ProMet: 3.566 ± 2.174
2.14ProAsn: 2.14 ± 0.942
4.28ProPro: 4.28 ± 4.328
2.14ProGln: 2.14 ± 0.821
3.566ProArg: 3.566 ± 0.978
4.993ProSer: 4.993 ± 1.379
2.853ProThr: 2.853 ± 0.998
3.566ProVal: 3.566 ± 1.623
0.713ProTrp: 0.713 ± 0.508
1.427ProTyr: 1.427 ± 0.542
0.0ProXaa: 0.0 ± 0.0
Gln
3.566GlnAla: 3.566 ± 1.723
0.0GlnCys: 0.0 ± 0.0
2.14GlnAsp: 2.14 ± 1.098
2.14GlnGlu: 2.14 ± 1.094
2.14GlnPhe: 2.14 ± 1.094
3.566GlnGly: 3.566 ± 1.096
0.713GlnHis: 0.713 ± 0.641
2.14GlnIle: 2.14 ± 0.994
2.14GlnLys: 2.14 ± 0.747
2.14GlnLeu: 2.14 ± 1.222
2.853GlnMet: 2.853 ± 1.105
2.853GlnAsn: 2.853 ± 1.809
2.14GlnPro: 2.14 ± 0.821
2.853GlnGln: 2.853 ± 2.562
8.559GlnArg: 8.559 ± 4.004
1.427GlnSer: 1.427 ± 1.015
3.566GlnThr: 3.566 ± 1.623
2.853GlnVal: 2.853 ± 1.174
0.713GlnTrp: 0.713 ± 0.508
3.566GlnTyr: 3.566 ± 1.246
0.0GlnXaa: 0.0 ± 0.0
Arg
10.699ArgAla: 10.699 ± 2.644
0.0ArgCys: 0.0 ± 0.0
4.993ArgAsp: 4.993 ± 1.867
5.706ArgGlu: 5.706 ± 3.207
2.14ArgPhe: 2.14 ± 0.747
2.14ArgGly: 2.14 ± 1.523
0.713ArgHis: 0.713 ± 0.508
4.28ArgIle: 4.28 ± 1.46
7.133ArgLys: 7.133 ± 3.439
6.419ArgLeu: 6.419 ± 1.145
2.853ArgMet: 2.853 ± 0.635
3.566ArgAsn: 3.566 ± 0.804
4.993ArgPro: 4.993 ± 1.496
5.706ArgGln: 5.706 ± 1.265
9.272ArgArg: 9.272 ± 1.949
2.853ArgSer: 2.853 ± 1.121
0.0ArgThr: 0.0 ± 0.0
7.846ArgVal: 7.846 ± 0.77
0.713ArgTrp: 0.713 ± 0.508
3.566ArgTyr: 3.566 ± 1.865
0.0ArgXaa: 0.0 ± 0.0
Ser
4.993SerAla: 4.993 ± 1.13
0.713SerCys: 0.713 ± 0.738
3.566SerAsp: 3.566 ± 2.538
4.28SerGlu: 4.28 ± 1.531
0.713SerPhe: 0.713 ± 0.641
5.706SerGly: 5.706 ± 2.052
0.713SerHis: 0.713 ± 0.508
2.14SerIle: 2.14 ± 0.994
0.0SerLys: 0.0 ± 0.0
3.566SerLeu: 3.566 ± 1.24
0.0SerMet: 0.0 ± 0.0
1.427SerAsn: 1.427 ± 0.542
4.993SerPro: 4.993 ± 0.966
4.993SerGln: 4.993 ± 1.365
4.28SerArg: 4.28 ± 1.064
2.853SerSer: 2.853 ± 2.031
4.993SerThr: 4.993 ± 1.104
2.14SerVal: 2.14 ± 0.942
1.427SerTrp: 1.427 ± 0.542
3.566SerTyr: 3.566 ± 1.096
0.0SerXaa: 0.0 ± 0.0
Thr
4.993ThrAla: 4.993 ± 0.966
0.713ThrCys: 0.713 ± 0.508
2.14ThrAsp: 2.14 ± 2.066
3.566ThrGlu: 3.566 ± 1.375
1.427ThrPhe: 1.427 ± 1.015
4.28ThrGly: 4.28 ± 1.035
1.427ThrHis: 1.427 ± 0.664
1.427ThrIle: 1.427 ± 0.918
1.427ThrLys: 1.427 ± 0.542
2.853ThrLeu: 2.853 ± 1.164
1.427ThrMet: 1.427 ± 1.015
4.28ThrAsn: 4.28 ± 1.53
7.133ThrPro: 7.133 ± 1.512
2.14ThrGln: 2.14 ± 1.08
4.28ThrArg: 4.28 ± 1.208
4.993ThrSer: 4.993 ± 1.892
4.28ThrThr: 4.28 ± 3.359
2.853ThrVal: 2.853 ± 1.813
0.713ThrTrp: 0.713 ± 0.508
1.427ThrTyr: 1.427 ± 0.542
0.0ThrXaa: 0.0 ± 0.0
Val
4.993ValAla: 4.993 ± 2.886
1.427ValCys: 1.427 ± 0.542
4.993ValAsp: 4.993 ± 3.509
1.427ValGlu: 1.427 ± 0.893
0.713ValPhe: 0.713 ± 0.508
2.14ValGly: 2.14 ± 1.28
0.0ValHis: 0.0 ± 0.0
3.566ValIle: 3.566 ± 2.096
4.28ValLys: 4.28 ± 1.53
3.566ValLeu: 3.566 ± 1.207
2.14ValMet: 2.14 ± 0.747
4.28ValAsn: 4.28 ± 0.717
3.566ValPro: 3.566 ± 1.198
4.28ValGln: 4.28 ± 2.392
1.427ValArg: 1.427 ± 0.542
4.28ValSer: 4.28 ± 1.181
7.133ValThr: 7.133 ± 3.39
4.28ValVal: 4.28 ± 3.675
0.0ValTrp: 0.0 ± 0.0
2.853ValTyr: 2.853 ± 1.542
0.0ValXaa: 0.0 ± 0.0
Trp
0.713TrpAla: 0.713 ± 0.738
0.0TrpCys: 0.0 ± 0.0
1.427TrpAsp: 1.427 ± 1.015
1.427TrpGlu: 1.427 ± 0.664
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.713TrpLys: 0.713 ± 0.738
1.427TrpLeu: 1.427 ± 1.015
0.0TrpMet: 0.0 ± 0.0
0.713TrpAsn: 0.713 ± 0.508
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.427TrpArg: 1.427 ± 1.015
0.713TrpSer: 0.713 ± 0.738
1.427TrpThr: 1.427 ± 1.015
0.0TrpVal: 0.0 ± 0.0
0.713TrpTrp: 0.713 ± 0.508
0.713TrpTyr: 0.713 ± 0.738
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.853TyrAla: 2.853 ± 0.635
0.713TyrCys: 0.713 ± 0.738
2.14TyrAsp: 2.14 ± 0.747
1.427TyrGlu: 1.427 ± 1.226
2.853TyrPhe: 2.853 ± 2.031
2.853TyrGly: 2.853 ± 2.443
2.14TyrHis: 2.14 ± 1.191
4.993TyrIle: 4.993 ± 2.463
2.14TyrLys: 2.14 ± 1.821
2.14TyrLeu: 2.14 ± 1.28
1.427TyrMet: 1.427 ± 0.918
2.14TyrAsn: 2.14 ± 1.523
1.427TyrPro: 1.427 ± 0.893
1.427TyrGln: 1.427 ± 0.664
5.706TyrArg: 5.706 ± 0.871
2.14TyrSer: 2.14 ± 1.191
3.566TyrThr: 3.566 ± 1.311
2.14TyrVal: 2.14 ± 3.529
0.713TyrTrp: 0.713 ± 0.508
5.706TyrTyr: 5.706 ± 4.204
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1403 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski