Amino acid dipepetide frequency for Pyrenophora teres f. teres (strain 0-1) (Barley net blotch fungus) (Drechslera teres f. teres)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.02AlaAla: 9.02 ± 0.06
1.037AlaCys: 1.037 ± 0.014
4.272AlaAsp: 4.272 ± 0.028
5.254AlaGlu: 5.254 ± 0.047
3.146AlaPhe: 3.146 ± 0.028
5.664AlaGly: 5.664 ± 0.041
1.947AlaHis: 1.947 ± 0.018
4.309AlaIle: 4.309 ± 0.034
4.58AlaLys: 4.58 ± 0.037
7.541AlaLeu: 7.541 ± 0.049
2.065AlaMet: 2.065 ± 0.021
3.19AlaAsn: 3.19 ± 0.029
5.279AlaPro: 5.279 ± 0.053
3.697AlaGln: 3.697 ± 0.03
4.908AlaArg: 4.908 ± 0.033
7.309AlaSer: 7.309 ± 0.051
5.573AlaThr: 5.573 ± 0.036
5.248AlaVal: 5.248 ± 0.041
1.192AlaTrp: 1.192 ± 0.017
2.322AlaTyr: 2.322 ± 0.022
0.0AlaXaa: 0.0 ± 0.0
Cys
0.919CysAla: 0.919 ± 0.014
0.222CysCys: 0.222 ± 0.007
0.635CysAsp: 0.635 ± 0.012
0.584CysGlu: 0.584 ± 0.009
0.498CysPhe: 0.498 ± 0.009
0.891CysGly: 0.891 ± 0.016
0.287CysHis: 0.287 ± 0.008
0.705CysIle: 0.705 ± 0.013
0.54CysLys: 0.54 ± 0.01
1.098CysLeu: 1.098 ± 0.015
0.28CysMet: 0.28 ± 0.008
0.45CysAsn: 0.45 ± 0.011
0.615CysPro: 0.615 ± 0.013
0.405CysGln: 0.405 ± 0.008
0.66CysArg: 0.66 ± 0.012
0.841CysSer: 0.841 ± 0.013
0.711CysThr: 0.711 ± 0.011
0.752CysVal: 0.752 ± 0.012
0.185CysTrp: 0.185 ± 0.006
0.347CysTyr: 0.347 ± 0.007
0.0CysXaa: 0.0 ± 0.0
Asp
5.069AspAla: 5.069 ± 0.031
0.599AspCys: 0.599 ± 0.012
4.444AspAsp: 4.444 ± 0.044
4.592AspGlu: 4.592 ± 0.041
2.223AspPhe: 2.223 ± 0.022
3.882AspGly: 3.882 ± 0.03
1.232AspHis: 1.232 ± 0.015
3.079AspIle: 3.079 ± 0.024
2.553AspLys: 2.553 ± 0.027
4.736AspLeu: 4.736 ± 0.028
1.489AspMet: 1.489 ± 0.017
1.92AspAsn: 1.92 ± 0.019
3.171AspPro: 3.171 ± 0.027
1.881AspGln: 1.881 ± 0.021
2.969AspArg: 2.969 ± 0.026
3.969AspSer: 3.969 ± 0.031
3.187AspThr: 3.187 ± 0.025
3.793AspVal: 3.793 ± 0.029
0.915AspTrp: 0.915 ± 0.013
1.665AspTyr: 1.665 ± 0.02
0.0AspXaa: 0.0 ± 0.0
Glu
5.634GluAla: 5.634 ± 0.046
0.605GluCys: 0.605 ± 0.011
4.442GluAsp: 4.442 ± 0.041
5.851GluGlu: 5.851 ± 0.061
1.872GluPhe: 1.872 ± 0.022
3.788GluGly: 3.788 ± 0.03
1.536GluHis: 1.536 ± 0.019
2.952GluIle: 2.952 ± 0.022
4.057GluLys: 4.057 ± 0.035
5.178GluLeu: 5.178 ± 0.035
1.536GluMet: 1.536 ± 0.016
2.23GluAsn: 2.23 ± 0.022
2.828GluPro: 2.828 ± 0.044
2.71GluGln: 2.71 ± 0.025
4.036GluArg: 4.036 ± 0.038
4.022GluSer: 4.022 ± 0.033
3.376GluThr: 3.376 ± 0.032
3.543GluVal: 3.543 ± 0.026
0.902GluTrp: 0.902 ± 0.013
1.734GluTyr: 1.734 ± 0.018
0.0GluXaa: 0.0 ± 0.0
Phe
3.123PheAla: 3.123 ± 0.027
0.524PheCys: 0.524 ± 0.01
2.293PheAsp: 2.293 ± 0.021
2.113PheGlu: 2.113 ± 0.021
1.54PhePhe: 1.54 ± 0.022
2.78PheGly: 2.78 ± 0.029
0.847PheHis: 0.847 ± 0.013
1.703PheIle: 1.703 ± 0.02
1.569PheLys: 1.569 ± 0.02
3.166PheLeu: 3.166 ± 0.03
0.764PheMet: 0.764 ± 0.014
1.477PheAsn: 1.477 ± 0.018
1.85PhePro: 1.85 ± 0.019
1.36PheGln: 1.36 ± 0.017
1.862PheArg: 1.862 ± 0.02
2.85PheSer: 2.85 ± 0.026
2.207PheThr: 2.207 ± 0.024
2.311PheVal: 2.311 ± 0.024
0.602PheTrp: 0.602 ± 0.013
1.053PheTyr: 1.053 ± 0.015
0.0PheXaa: 0.0 ± 0.0
Gly
5.308GlyAla: 5.308 ± 0.045
0.828GlyCys: 0.828 ± 0.014
3.552GlyAsp: 3.552 ± 0.028
3.676GlyGlu: 3.676 ± 0.028
2.715GlyPhe: 2.715 ± 0.026
5.811GlyGly: 5.811 ± 0.06
1.638GlyHis: 1.638 ± 0.018
3.381GlyIle: 3.381 ± 0.029
3.686GlyLys: 3.686 ± 0.034
5.661GlyLeu: 5.661 ± 0.041
1.695GlyMet: 1.695 ± 0.02
2.532GlyAsn: 2.532 ± 0.025
3.197GlyPro: 3.197 ± 0.031
2.506GlyGln: 2.506 ± 0.027
3.931GlyArg: 3.931 ± 0.036
5.312GlySer: 5.312 ± 0.042
3.919GlyThr: 3.919 ± 0.029
4.256GlyVal: 4.256 ± 0.035
1.131GlyTrp: 1.131 ± 0.015
2.118GlyTyr: 2.118 ± 0.022
0.0GlyXaa: 0.0 ± 0.0
His
2.004HisAla: 2.004 ± 0.02
0.323HisCys: 0.323 ± 0.009
1.374HisAsp: 1.374 ± 0.018
1.377HisGlu: 1.377 ± 0.015
0.919HisPhe: 0.919 ± 0.014
1.691HisGly: 1.691 ± 0.02
0.884HisHis: 0.884 ± 0.015
1.254HisIle: 1.254 ± 0.017
1.001HisLys: 1.001 ± 0.015
2.177HisLeu: 2.177 ± 0.023
0.559HisMet: 0.559 ± 0.01
0.894HisAsn: 0.894 ± 0.014
1.618HisPro: 1.618 ± 0.019
1.053HisGln: 1.053 ± 0.017
1.46HisArg: 1.46 ± 0.017
1.818HisSer: 1.818 ± 0.021
1.394HisThr: 1.394 ± 0.017
1.558HisVal: 1.558 ± 0.016
0.341HisTrp: 0.341 ± 0.007
0.692HisTyr: 0.692 ± 0.012
0.0HisXaa: 0.0 ± 0.0
Ile
4.343IleAla: 4.343 ± 0.032
0.706IleCys: 0.706 ± 0.013
2.867IleAsp: 2.867 ± 0.028
2.937IleGlu: 2.937 ± 0.026
1.861IlePhe: 1.861 ± 0.019
3.078IleGly: 3.078 ± 0.029
1.201IleHis: 1.201 ± 0.015
2.418IleIle: 2.418 ± 0.025
2.352IleLys: 2.352 ± 0.02
4.263IleLeu: 4.263 ± 0.037
1.044IleMet: 1.044 ± 0.013
1.819IleAsn: 1.819 ± 0.016
3.037IlePro: 3.037 ± 0.022
1.92IleGln: 1.92 ± 0.019
2.719IleArg: 2.719 ± 0.025
3.643IleSer: 3.643 ± 0.03
2.981IleThr: 2.981 ± 0.027
3.11IleVal: 3.11 ± 0.027
0.68IleTrp: 0.68 ± 0.012
1.39IleTyr: 1.39 ± 0.017
0.0IleXaa: 0.0 ± 0.0
Lys
4.676LysAla: 4.676 ± 0.037
0.498LysCys: 0.498 ± 0.009
3.096LysAsp: 3.096 ± 0.028
3.76LysGlu: 3.76 ± 0.037
1.488LysPhe: 1.488 ± 0.021
3.205LysGly: 3.205 ± 0.03
1.231LysHis: 1.231 ± 0.013
2.367LysIle: 2.367 ± 0.021
3.935LysLys: 3.935 ± 0.055
4.295LysLeu: 4.295 ± 0.033
1.137LysMet: 1.137 ± 0.017
1.931LysAsn: 1.931 ± 0.021
2.995LysPro: 2.995 ± 0.03
2.103LysGln: 2.103 ± 0.02
3.646LysArg: 3.646 ± 0.028
3.606LysSer: 3.606 ± 0.031
3.119LysThr: 3.119 ± 0.024
2.951LysVal: 2.951 ± 0.027
0.699LysTrp: 0.699 ± 0.01
1.428LysTyr: 1.428 ± 0.018
0.0LysXaa: 0.0 ± 0.0
Leu
7.498LeuAla: 7.498 ± 0.056
1.131LeuCys: 1.131 ± 0.015
4.995LeuAsp: 4.995 ± 0.034
5.332LeuGlu: 5.332 ± 0.042
3.095LeuPhe: 3.095 ± 0.027
5.526LeuGly: 5.526 ± 0.041
2.159LeuHis: 2.159 ± 0.02
3.716LeuIle: 3.716 ± 0.03
4.316LeuLys: 4.316 ± 0.029
7.75LeuLeu: 7.75 ± 0.063
1.721LeuMet: 1.721 ± 0.018
3.142LeuAsn: 3.142 ± 0.026
5.397LeuPro: 5.397 ± 0.037
3.843LeuGln: 3.843 ± 0.035
5.466LeuArg: 5.466 ± 0.039
6.813LeuSer: 6.813 ± 0.04
4.674LeuThr: 4.674 ± 0.035
5.193LeuVal: 5.193 ± 0.037
1.11LeuTrp: 1.11 ± 0.016
2.297LeuTyr: 2.297 ± 0.025
0.0LeuXaa: 0.0 ± 0.0
Met
2.264MetAla: 2.264 ± 0.02
0.25MetCys: 0.25 ± 0.008
1.353MetAsp: 1.353 ± 0.016
1.352MetGlu: 1.352 ± 0.016
0.757MetPhe: 0.757 ± 0.013
1.529MetGly: 1.529 ± 0.022
0.53MetHis: 0.53 ± 0.01
0.976MetIle: 0.976 ± 0.013
1.124MetLys: 1.124 ± 0.017
1.932MetLeu: 1.932 ± 0.02
0.628MetMet: 0.628 ± 0.011
0.864MetAsn: 0.864 ± 0.014
1.397MetPro: 1.397 ± 0.017
0.986MetGln: 0.986 ± 0.016
1.358MetArg: 1.358 ± 0.013
1.999MetSer: 1.999 ± 0.02
1.338MetThr: 1.338 ± 0.016
1.334MetVal: 1.334 ± 0.016
0.274MetTrp: 0.274 ± 0.008
0.606MetTyr: 0.606 ± 0.011
0.0MetXaa: 0.0 ± 0.0
Asn
3.372AsnAla: 3.372 ± 0.026
0.427AsnCys: 0.427 ± 0.01
2.043AsnAsp: 2.043 ± 0.021
2.112AsnGlu: 2.112 ± 0.021
1.405AsnPhe: 1.405 ± 0.017
3.023AsnGly: 3.023 ± 0.027
0.874AsnHis: 0.874 ± 0.013
2.062AsnIle: 2.062 ± 0.021
1.796AsnLys: 1.796 ± 0.018
3.162AsnLeu: 3.162 ± 0.026
0.927AsnMet: 0.927 ± 0.014
1.631AsnAsn: 1.631 ± 0.025
2.424AsnPro: 2.424 ± 0.027
1.37AsnGln: 1.37 ± 0.019
1.946AsnArg: 1.946 ± 0.02
2.735AsnSer: 2.735 ± 0.024
2.473AsnThr: 2.473 ± 0.024
2.407AsnVal: 2.407 ± 0.022
0.57AsnTrp: 0.57 ± 0.011
1.089AsnTyr: 1.089 ± 0.014
0.0AsnXaa: 0.0 ± 0.0
Pro
5.414ProAla: 5.414 ± 0.048
0.47ProCys: 0.47 ± 0.01
3.109ProAsp: 3.109 ± 0.023
3.758ProGlu: 3.758 ± 0.033
2.018ProPhe: 2.018 ± 0.02
3.695ProGly: 3.695 ± 0.033
1.431ProHis: 1.431 ± 0.018
2.636ProIle: 2.636 ± 0.021
3.007ProLys: 3.007 ± 0.031
4.58ProLeu: 4.58 ± 0.032
1.216ProMet: 1.216 ± 0.015
2.393ProAsn: 2.393 ± 0.024
5.349ProPro: 5.349 ± 0.071
2.68ProGln: 2.68 ± 0.033
3.358ProArg: 3.358 ± 0.036
5.927ProSer: 5.927 ± 0.057
4.514ProThr: 4.514 ± 0.038
3.628ProVal: 3.628 ± 0.036
0.69ProTrp: 0.69 ± 0.012
1.593ProTyr: 1.593 ± 0.021
0.0ProXaa: 0.0 ± 0.0
Gln
3.586GlnAla: 3.586 ± 0.03
0.443GlnCys: 0.443 ± 0.009
2.239GlnAsp: 2.239 ± 0.024
2.527GlnGlu: 2.527 ± 0.027
1.277GlnPhe: 1.277 ± 0.014
2.437GlnGly: 2.437 ± 0.025
1.257GlnHis: 1.257 ± 0.019
1.885GlnIle: 1.885 ± 0.023
2.132GlnLys: 2.132 ± 0.025
3.463GlnLeu: 3.463 ± 0.03
0.932GlnMet: 0.932 ± 0.016
1.597GlnAsn: 1.597 ± 0.02
2.697GlnPro: 2.697 ± 0.032
2.842GlnGln: 2.842 ± 0.054
2.756GlnArg: 2.756 ± 0.026
3.156GlnSer: 3.156 ± 0.028
2.44GlnThr: 2.44 ± 0.022
2.179GlnVal: 2.179 ± 0.022
0.567GlnTrp: 0.567 ± 0.01
1.298GlnTyr: 1.298 ± 0.015
0.0GlnXaa: 0.0 ± 0.0
Arg
4.659ArgAla: 4.659 ± 0.03
0.654ArgCys: 0.654 ± 0.011
3.271ArgAsp: 3.271 ± 0.03
3.791ArgGlu: 3.791 ± 0.04
2.032ArgPhe: 2.032 ± 0.019
3.596ArgGly: 3.596 ± 0.037
1.518ArgHis: 1.518 ± 0.019
2.925ArgIle: 2.925 ± 0.026
3.639ArgLys: 3.639 ± 0.031
5.156ArgLeu: 5.156 ± 0.036
1.382ArgMet: 1.382 ± 0.016
2.383ArgAsn: 2.383 ± 0.021
3.465ArgPro: 3.465 ± 0.034
2.633ArgGln: 2.633 ± 0.028
4.801ArgArg: 4.801 ± 0.049
4.58ArgSer: 4.58 ± 0.045
3.407ArgThr: 3.407 ± 0.028
3.202ArgVal: 3.202 ± 0.026
0.863ArgTrp: 0.863 ± 0.014
1.663ArgTyr: 1.663 ± 0.021
0.0ArgXaa: 0.0 ± 0.0
Ser
6.539SerAla: 6.539 ± 0.042
0.78SerCys: 0.78 ± 0.015
4.171SerAsp: 4.171 ± 0.034
4.109SerGlu: 4.109 ± 0.037
2.866SerPhe: 2.866 ± 0.024
5.193SerGly: 5.193 ± 0.037
1.921SerHis: 1.921 ± 0.019
3.884SerIle: 3.884 ± 0.033
3.826SerLys: 3.826 ± 0.032
6.614SerLeu: 6.614 ± 0.04
1.785SerMet: 1.785 ± 0.018
3.051SerAsn: 3.051 ± 0.028
5.525SerPro: 5.525 ± 0.055
3.219SerGln: 3.219 ± 0.029
4.702SerArg: 4.702 ± 0.048
8.259SerSer: 8.259 ± 0.07
5.688SerThr: 5.688 ± 0.045
4.417SerVal: 4.417 ± 0.029
1.02SerTrp: 1.02 ± 0.014
2.115SerTyr: 2.115 ± 0.02
0.0SerXaa: 0.0 ± 0.0
Thr
5.459ThrAla: 5.459 ± 0.036
0.754ThrCys: 0.754 ± 0.012
2.909ThrAsp: 2.909 ± 0.021
3.23ThrGlu: 3.23 ± 0.032
2.252ThrPhe: 2.252 ± 0.02
4.085ThrGly: 4.085 ± 0.034
1.4ThrHis: 1.4 ± 0.018
3.154ThrIle: 3.154 ± 0.028
2.926ThrLys: 2.926 ± 0.024
5.31ThrLeu: 5.31 ± 0.035
1.297ThrMet: 1.297 ± 0.016
2.276ThrAsn: 2.276 ± 0.022
4.86ThrPro: 4.86 ± 0.053
2.304ThrGln: 2.304 ± 0.023
3.201ThrArg: 3.201 ± 0.025
5.458ThrSer: 5.458 ± 0.042
4.649ThrThr: 4.649 ± 0.037
3.726ThrVal: 3.726 ± 0.028
0.868ThrTrp: 0.868 ± 0.015
1.684ThrTyr: 1.684 ± 0.021
0.0ThrXaa: 0.0 ± 0.0
Val
5.268ValAla: 5.268 ± 0.04
0.775ValCys: 0.775 ± 0.014
3.67ValAsp: 3.67 ± 0.025
4.013ValGlu: 4.013 ± 0.029
2.336ValPhe: 2.336 ± 0.025
4.037ValGly: 4.037 ± 0.032
1.405ValHis: 1.405 ± 0.015
2.804ValIle: 2.804 ± 0.026
3.066ValLys: 3.066 ± 0.028
5.289ValLeu: 5.289 ± 0.04
1.313ValMet: 1.313 ± 0.016
2.2ValAsn: 2.2 ± 0.021
3.625ValPro: 3.625 ± 0.031
2.48ValGln: 2.48 ± 0.026
3.334ValArg: 3.334 ± 0.029
4.374ValSer: 4.374 ± 0.032
3.497ValThr: 3.497 ± 0.027
4.24ValVal: 4.24 ± 0.032
0.843ValTrp: 0.843 ± 0.015
1.738ValTyr: 1.738 ± 0.018
0.0ValXaa: 0.0 ± 0.0
Trp
1.122TrpAla: 1.122 ± 0.017
0.2TrpCys: 0.2 ± 0.005
0.896TrpAsp: 0.896 ± 0.014
0.842TrpGlu: 0.842 ± 0.014
0.535TrpPhe: 0.535 ± 0.011
0.896TrpGly: 0.896 ± 0.015
0.347TrpHis: 0.347 ± 0.008
0.74TrpIle: 0.74 ± 0.013
0.818TrpLys: 0.818 ± 0.011
1.263TrpLeu: 1.263 ± 0.018
0.375TrpMet: 0.375 ± 0.008
0.641TrpAsn: 0.641 ± 0.011
0.577TrpPro: 0.577 ± 0.011
0.575TrpGln: 0.575 ± 0.01
0.878TrpArg: 0.878 ± 0.013
1.003TrpSer: 1.003 ± 0.016
0.907TrpThr: 0.907 ± 0.014
0.855TrpVal: 0.855 ± 0.015
0.27TrpTrp: 0.27 ± 0.008
0.427TrpTyr: 0.427 ± 0.009
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.276TyrAla: 2.276 ± 0.023
0.4TyrCys: 0.4 ± 0.008
1.735TyrAsp: 1.735 ± 0.021
1.618TyrGlu: 1.618 ± 0.02
1.16TyrPhe: 1.16 ± 0.016
2.047TyrGly: 2.047 ± 0.024
0.748TyrHis: 0.748 ± 0.012
1.42TyrIle: 1.42 ± 0.019
1.243TyrLys: 1.243 ± 0.016
2.541TyrLeu: 2.541 ± 0.023
0.704TyrMet: 0.704 ± 0.011
1.228TyrAsn: 1.228 ± 0.017
1.562TyrPro: 1.562 ± 0.018
1.145TyrGln: 1.145 ± 0.016
1.627TyrArg: 1.627 ± 0.018
2.006TyrSer: 2.006 ± 0.02
1.748TyrThr: 1.748 ± 0.018
1.606TyrVal: 1.606 ± 0.019
0.447TyrTrp: 0.447 ± 0.01
0.945TyrTyr: 0.945 ± 0.014
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 11705 proteins (5424802 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski