Amino acid dipepetide frequency for Slackia piriformis YIT 12062

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
14.045AlaAla: 14.045 ± 0.207
2.453AlaCys: 2.453 ± 0.079
6.257AlaAsp: 6.257 ± 0.122
7.159AlaGlu: 7.159 ± 0.15
4.883AlaPhe: 4.883 ± 0.114
8.763AlaGly: 8.763 ± 0.151
2.123AlaHis: 2.123 ± 0.065
5.829AlaIle: 5.829 ± 0.112
4.681AlaLys: 4.681 ± 0.101
11.454AlaLeu: 11.454 ± 0.176
3.246AlaMet: 3.246 ± 0.075
2.918AlaAsn: 2.918 ± 0.071
4.067AlaPro: 4.067 ± 0.106
3.722AlaGln: 3.722 ± 0.087
6.39AlaArg: 6.39 ± 0.12
7.536AlaSer: 7.536 ± 0.14
5.049AlaThr: 5.049 ± 0.098
8.415AlaVal: 8.415 ± 0.15
1.231AlaTrp: 1.231 ± 0.048
2.999AlaTyr: 2.999 ± 0.087
0.0AlaXaa: 0.0 ± 0.0
Cys
1.968CysAla: 1.968 ± 0.066
0.33CysCys: 0.33 ± 0.024
1.084CysAsp: 1.084 ± 0.043
1.121CysGlu: 1.121 ± 0.042
0.631CysPhe: 0.631 ± 0.03
1.913CysGly: 1.913 ± 0.067
0.336CysHis: 0.336 ± 0.029
0.934CysIle: 0.934 ± 0.04
0.596CysLys: 0.596 ± 0.03
1.434CysLeu: 1.434 ± 0.053
0.513CysMet: 0.513 ± 0.031
0.455CysAsn: 0.455 ± 0.029
0.831CysPro: 0.831 ± 0.045
0.353CysGln: 0.353 ± 0.025
0.854CysArg: 0.854 ± 0.037
1.081CysSer: 1.081 ± 0.043
0.823CysThr: 0.823 ± 0.039
1.537CysVal: 1.537 ± 0.063
0.163CysTrp: 0.163 ± 0.019
0.438CysTyr: 0.438 ± 0.03
0.0CysXaa: 0.0 ± 0.0
Asp
7.58AspAla: 7.58 ± 0.135
0.801AspCys: 0.801 ± 0.039
3.366AspAsp: 3.366 ± 0.089
5.407AspGlu: 5.407 ± 0.102
2.561AspPhe: 2.561 ± 0.065
4.829AspGly: 4.829 ± 0.114
0.911AspHis: 0.911 ± 0.04
3.451AspIle: 3.451 ± 0.078
2.112AspLys: 2.112 ± 0.064
4.893AspLeu: 4.893 ± 0.099
1.785AspMet: 1.785 ± 0.056
1.429AspAsn: 1.429 ± 0.051
2.661AspPro: 2.661 ± 0.075
1.317AspGln: 1.317 ± 0.053
3.126AspArg: 3.126 ± 0.09
3.212AspSer: 3.212 ± 0.083
2.561AspThr: 2.561 ± 0.069
4.903AspVal: 4.903 ± 0.094
0.605AspTrp: 0.605 ± 0.03
1.852AspTyr: 1.852 ± 0.057
0.0AspXaa: 0.0 ± 0.0
Glu
7.682GluAla: 7.682 ± 0.145
0.933GluCys: 0.933 ± 0.042
3.802GluAsp: 3.802 ± 0.087
5.764GluGlu: 5.764 ± 0.134
2.333GluPhe: 2.333 ± 0.063
5.697GluGly: 5.697 ± 0.111
1.557GluHis: 1.557 ± 0.05
3.382GluIle: 3.382 ± 0.077
3.547GluLys: 3.547 ± 0.091
6.017GluLeu: 6.017 ± 0.114
1.809GluMet: 1.809 ± 0.06
2.406GluAsn: 2.406 ± 0.068
2.368GluPro: 2.368 ± 0.067
2.403GluGln: 2.403 ± 0.058
4.946GluArg: 4.946 ± 0.101
4.015GluSer: 4.015 ± 0.092
3.416GluThr: 3.416 ± 0.095
4.526GluVal: 4.526 ± 0.095
0.629GluTrp: 0.629 ± 0.032
1.83GluTyr: 1.83 ± 0.064
0.0GluXaa: 0.0 ± 0.0
Phe
4.63PheAla: 4.63 ± 0.103
0.778PheCys: 0.778 ± 0.037
3.124PheAsp: 3.124 ± 0.077
2.759PheGlu: 2.759 ± 0.071
1.73PhePhe: 1.73 ± 0.063
3.815PheGly: 3.815 ± 0.084
0.664PheHis: 0.664 ± 0.03
1.978PheIle: 1.978 ± 0.065
1.321PheLys: 1.321 ± 0.047
3.504PheLeu: 3.504 ± 0.099
1.091PheMet: 1.091 ± 0.042
1.117PheAsn: 1.117 ± 0.047
1.394PhePro: 1.394 ± 0.049
0.876PheGln: 0.876 ± 0.039
1.627PheArg: 1.627 ± 0.045
3.159PheSer: 3.159 ± 0.084
1.867PheThr: 1.867 ± 0.053
3.89PheVal: 3.89 ± 0.091
0.446PheTrp: 0.446 ± 0.03
1.116PheTyr: 1.116 ± 0.048
0.0PheXaa: 0.0 ± 0.0
Gly
8.097GlyAla: 8.097 ± 0.121
1.674GlyCys: 1.674 ± 0.057
4.092GlyAsp: 4.092 ± 0.095
4.789GlyGlu: 4.789 ± 0.097
3.704GlyPhe: 3.704 ± 0.076
6.25GlyGly: 6.25 ± 0.146
1.437GlyHis: 1.437 ± 0.051
5.292GlyIle: 5.292 ± 0.102
3.864GlyLys: 3.864 ± 0.084
7.071GlyLeu: 7.071 ± 0.137
2.61GlyMet: 2.61 ± 0.075
2.475GlyAsn: 2.475 ± 0.066
2.205GlyPro: 2.205 ± 0.064
2.032GlyGln: 2.032 ± 0.053
4.378GlyArg: 4.378 ± 0.101
5.449GlySer: 5.449 ± 0.109
4.105GlyThr: 4.105 ± 0.098
7.227GlyVal: 7.227 ± 0.125
0.939GlyTrp: 0.939 ± 0.059
2.616GlyTyr: 2.616 ± 0.077
0.0GlyXaa: 0.0 ± 0.0
His
2.23HisAla: 2.23 ± 0.078
0.288HisCys: 0.288 ± 0.021
1.232HisAsp: 1.232 ± 0.049
1.286HisGlu: 1.286 ± 0.052
0.699HisPhe: 0.699 ± 0.033
1.645HisGly: 1.645 ± 0.052
0.418HisHis: 0.418 ± 0.029
1.089HisIle: 1.089 ± 0.039
0.611HisLys: 0.611 ± 0.029
1.407HisLeu: 1.407 ± 0.055
0.515HisMet: 0.515 ± 0.037
0.508HisAsn: 0.508 ± 0.025
1.021HisPro: 1.021 ± 0.044
0.448HisGln: 0.448 ± 0.027
1.014HisArg: 1.014 ± 0.04
0.969HisSer: 0.969 ± 0.042
0.881HisThr: 0.881 ± 0.037
1.61HisVal: 1.61 ± 0.057
0.17HisTrp: 0.17 ± 0.018
0.571HisTyr: 0.571 ± 0.025
0.0HisXaa: 0.0 ± 0.0
Ile
7.051IleAla: 7.051 ± 0.126
0.848IleCys: 0.848 ± 0.038
3.879IleAsp: 3.879 ± 0.082
4.122IleGlu: 4.122 ± 0.092
1.744IlePhe: 1.744 ± 0.066
4.468IleGly: 4.468 ± 0.105
0.824IleHis: 0.824 ± 0.035
2.565IleIle: 2.565 ± 0.089
1.858IleLys: 1.858 ± 0.058
4.158IleLeu: 4.158 ± 0.105
1.431IleMet: 1.431 ± 0.058
1.462IleAsn: 1.462 ± 0.049
2.528IlePro: 2.528 ± 0.072
1.236IleGln: 1.236 ± 0.042
2.391IleArg: 2.391 ± 0.06
3.162IleSer: 3.162 ± 0.084
2.595IleThr: 2.595 ± 0.068
5.071IleVal: 5.071 ± 0.087
0.491IleTrp: 0.491 ± 0.029
1.244IleTyr: 1.244 ± 0.049
0.0IleXaa: 0.0 ± 0.0
Lys
4.58LysAla: 4.58 ± 0.105
0.448LysCys: 0.448 ± 0.027
2.41LysAsp: 2.41 ± 0.062
3.043LysGlu: 3.043 ± 0.085
1.054LysPhe: 1.054 ± 0.046
3.207LysGly: 3.207 ± 0.084
0.848LysHis: 0.848 ± 0.038
1.893LysIle: 1.893 ± 0.055
2.806LysLys: 2.806 ± 0.077
3.389LysLeu: 3.389 ± 0.069
1.161LysMet: 1.161 ± 0.038
1.592LysAsn: 1.592 ± 0.055
1.862LysPro: 1.862 ± 0.055
1.277LysGln: 1.277 ± 0.052
3.006LysArg: 3.006 ± 0.071
2.361LysSer: 2.361 ± 0.061
2.668LysThr: 2.668 ± 0.071
2.858LysVal: 2.858 ± 0.08
0.368LysTrp: 0.368 ± 0.033
0.928LysTyr: 0.928 ± 0.043
0.0LysXaa: 0.0 ± 0.0
Leu
10.451LeuAla: 10.451 ± 0.153
1.619LeuCys: 1.619 ± 0.049
5.609LeuAsp: 5.609 ± 0.107
5.734LeuGlu: 5.734 ± 0.113
3.972LeuPhe: 3.972 ± 0.1
7.234LeuGly: 7.234 ± 0.114
1.609LeuHis: 1.609 ± 0.058
4.451LeuIle: 4.451 ± 0.12
3.354LeuLys: 3.354 ± 0.083
7.97LeuLeu: 7.97 ± 0.153
2.515LeuMet: 2.515 ± 0.068
2.18LeuAsn: 2.18 ± 0.054
3.962LeuPro: 3.962 ± 0.089
2.17LeuGln: 2.17 ± 0.068
5.112LeuArg: 5.112 ± 0.117
6.606LeuSer: 6.606 ± 0.123
4.14LeuThr: 4.14 ± 0.094
7.377LeuVal: 7.377 ± 0.135
0.843LeuTrp: 0.843 ± 0.039
2.375LeuTyr: 2.375 ± 0.065
0.0LeuXaa: 0.0 ± 0.0
Met
3.394MetAla: 3.394 ± 0.077
0.415MetCys: 0.415 ± 0.029
1.522MetAsp: 1.522 ± 0.05
1.694MetGlu: 1.694 ± 0.052
0.988MetPhe: 0.988 ± 0.043
2.408MetGly: 2.408 ± 0.063
0.545MetHis: 0.545 ± 0.028
1.241MetIle: 1.241 ± 0.051
1.421MetLys: 1.421 ± 0.051
2.778MetLeu: 2.778 ± 0.069
0.831MetMet: 0.831 ± 0.038
1.059MetAsn: 1.059 ± 0.041
1.447MetPro: 1.447 ± 0.055
0.993MetGln: 0.993 ± 0.04
1.827MetArg: 1.827 ± 0.057
1.679MetSer: 1.679 ± 0.053
1.602MetThr: 1.602 ± 0.048
2.107MetVal: 2.107 ± 0.062
0.24MetTrp: 0.24 ± 0.023
0.651MetTyr: 0.651 ± 0.032
0.0MetXaa: 0.0 ± 0.0
Asn
3.54AsnAla: 3.54 ± 0.078
0.39AsnCys: 0.39 ± 0.026
1.64AsnAsp: 1.64 ± 0.053
2.037AsnGlu: 2.037 ± 0.057
0.941AsnPhe: 0.941 ± 0.042
2.383AsnGly: 2.383 ± 0.07
0.513AsnHis: 0.513 ± 0.031
1.597AsnIle: 1.597 ± 0.053
1.056AsnLys: 1.056 ± 0.047
2.526AsnLeu: 2.526 ± 0.062
0.821AsnMet: 0.821 ± 0.035
0.884AsnAsn: 0.884 ± 0.045
1.86AsnPro: 1.86 ± 0.061
0.789AsnGln: 0.789 ± 0.04
1.622AsnArg: 1.622 ± 0.046
1.431AsnSer: 1.431 ± 0.055
1.522AsnThr: 1.522 ± 0.049
2.435AsnVal: 2.435 ± 0.071
0.348AsnTrp: 0.348 ± 0.027
0.831AsnTyr: 0.831 ± 0.034
0.0AsnXaa: 0.0 ± 0.0
Pro
4.346ProAla: 4.346 ± 0.09
0.653ProCys: 0.653 ± 0.033
2.555ProAsp: 2.555 ± 0.061
3.436ProGlu: 3.436 ± 0.081
1.945ProPhe: 1.945 ± 0.057
2.929ProGly: 2.929 ± 0.075
0.891ProHis: 0.891 ± 0.043
1.843ProIle: 1.843 ± 0.059
1.63ProLys: 1.63 ± 0.058
3.717ProLeu: 3.717 ± 0.084
0.946ProMet: 0.946 ± 0.036
1.191ProAsn: 1.191 ± 0.049
1.064ProPro: 1.064 ± 0.049
1.342ProGln: 1.342 ± 0.058
2.095ProArg: 2.095 ± 0.061
2.843ProSer: 2.843 ± 0.073
1.96ProThr: 1.96 ± 0.067
3.441ProVal: 3.441 ± 0.081
0.465ProTrp: 0.465 ± 0.027
1.412ProTyr: 1.412 ± 0.051
0.0ProXaa: 0.0 ± 0.0
Gln
3.272GlnAla: 3.272 ± 0.076
0.368GlnCys: 0.368 ± 0.03
1.56GlnAsp: 1.56 ± 0.057
1.957GlnGlu: 1.957 ± 0.058
0.901GlnPhe: 0.901 ± 0.038
2.276GlnGly: 2.276 ± 0.055
0.553GlnHis: 0.553 ± 0.032
1.432GlnIle: 1.432 ± 0.052
1.302GlnLys: 1.302 ± 0.051
2.163GlnLeu: 2.163 ± 0.066
0.828GlnMet: 0.828 ± 0.038
0.909GlnAsn: 0.909 ± 0.043
1.142GlnPro: 1.142 ± 0.055
1.011GlnGln: 1.011 ± 0.05
1.993GlnArg: 1.993 ± 0.072
1.685GlnSer: 1.685 ± 0.059
1.424GlnThr: 1.424 ± 0.051
2.012GlnVal: 2.012 ± 0.057
0.276GlnTrp: 0.276 ± 0.022
0.734GlnTyr: 0.734 ± 0.039
0.0GlnXaa: 0.0 ± 0.0
Arg
5.809ArgAla: 5.809 ± 0.135
0.969ArgCys: 0.969 ± 0.043
3.226ArgAsp: 3.226 ± 0.086
4.32ArgGlu: 4.32 ± 0.095
2.541ArgPhe: 2.541 ± 0.068
3.789ArgGly: 3.789 ± 0.092
1.107ArgHis: 1.107 ± 0.039
3.602ArgIle: 3.602 ± 0.086
2.671ArgLys: 2.671 ± 0.08
4.943ArgLeu: 4.943 ± 0.113
2.088ArgMet: 2.088 ± 0.062
1.807ArgAsn: 1.807 ± 0.065
2.21ArgPro: 2.21 ± 0.064
1.547ArgGln: 1.547 ± 0.058
4.147ArgArg: 4.147 ± 0.108
3.354ArgSer: 3.354 ± 0.088
2.891ArgThr: 2.891 ± 0.068
4.288ArgVal: 4.288 ± 0.099
0.545ArgTrp: 0.545 ± 0.029
1.843ArgTyr: 1.843 ± 0.056
0.0ArgXaa: 0.0 ± 0.0
Ser
6.823SerAla: 6.823 ± 0.116
1.162SerCys: 1.162 ± 0.05
3.809SerAsp: 3.809 ± 0.103
3.84SerGlu: 3.84 ± 0.082
2.929SerPhe: 2.929 ± 0.076
5.224SerGly: 5.224 ± 0.096
1.174SerHis: 1.174 ± 0.043
3.575SerIle: 3.575 ± 0.084
2.411SerLys: 2.411 ± 0.07
5.704SerLeu: 5.704 ± 0.122
1.972SerMet: 1.972 ± 0.064
1.868SerAsn: 1.868 ± 0.055
2.418SerPro: 2.418 ± 0.063
1.792SerGln: 1.792 ± 0.065
3.579SerArg: 3.579 ± 0.096
4.964SerSer: 4.964 ± 0.137
3.059SerThr: 3.059 ± 0.093
5.024SerVal: 5.024 ± 0.1
0.731SerTrp: 0.731 ± 0.035
2.023SerTyr: 2.023 ± 0.059
0.0SerXaa: 0.0 ± 0.0
Thr
4.731ThrAla: 4.731 ± 0.099
0.898ThrCys: 0.898 ± 0.041
2.669ThrAsp: 2.669 ± 0.067
2.763ThrGlu: 2.763 ± 0.073
2.023ThrPhe: 2.023 ± 0.077
4.313ThrGly: 4.313 ± 0.096
1.034ThrHis: 1.034 ± 0.042
2.751ThrIle: 2.751 ± 0.077
1.953ThrLys: 1.953 ± 0.064
4.708ThrLeu: 4.708 ± 0.107
1.349ThrMet: 1.349 ± 0.052
1.394ThrAsn: 1.394 ± 0.054
2.585ThrPro: 2.585 ± 0.078
1.369ThrGln: 1.369 ± 0.05
2.378ThrArg: 2.378 ± 0.064
2.938ThrSer: 2.938 ± 0.076
2.596ThrThr: 2.596 ± 0.068
4.355ThrVal: 4.355 ± 0.099
0.49ThrTrp: 0.49 ± 0.031
1.559ThrTyr: 1.559 ± 0.056
0.0ThrXaa: 0.0 ± 0.0
Val
8.913ValAla: 8.913 ± 0.155
1.657ValCys: 1.657 ± 0.055
4.901ValAsp: 4.901 ± 0.093
5.267ValGlu: 5.267 ± 0.111
3.662ValPhe: 3.662 ± 0.094
5.872ValGly: 5.872 ± 0.11
1.402ValHis: 1.402 ± 0.05
4.292ValIle: 4.292 ± 0.102
3.147ValLys: 3.147 ± 0.074
7.88ValLeu: 7.88 ± 0.131
2.205ValMet: 2.205 ± 0.06
2.283ValAsn: 2.283 ± 0.076
3.454ValPro: 3.454 ± 0.08
2.03ValGln: 2.03 ± 0.053
4.763ValArg: 4.763 ± 0.087
5.629ValSer: 5.629 ± 0.09
3.745ValThr: 3.745 ± 0.085
7.411ValVal: 7.411 ± 0.132
0.774ValTrp: 0.774 ± 0.035
2.107ValTyr: 2.107 ± 0.07
0.0ValXaa: 0.0 ± 0.0
Trp
0.981TrpAla: 0.981 ± 0.038
0.208TrpCys: 0.208 ± 0.025
0.54TrpAsp: 0.54 ± 0.029
0.591TrpGlu: 0.591 ± 0.03
0.463TrpPhe: 0.463 ± 0.025
0.881TrpGly: 0.881 ± 0.042
0.236TrpHis: 0.236 ± 0.021
0.568TrpIle: 0.568 ± 0.033
0.431TrpLys: 0.431 ± 0.027
0.984TrpLeu: 0.984 ± 0.043
0.356TrpMet: 0.356 ± 0.024
0.401TrpAsn: 0.401 ± 0.033
0.37TrpPro: 0.37 ± 0.027
0.32TrpGln: 0.32 ± 0.028
0.634TrpArg: 0.634 ± 0.035
0.548TrpSer: 0.548 ± 0.032
0.46TrpThr: 0.46 ± 0.031
0.771TrpVal: 0.771 ± 0.037
0.138TrpTrp: 0.138 ± 0.015
0.278TrpTyr: 0.278 ± 0.031
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.094TyrAla: 3.094 ± 0.071
0.506TyrCys: 0.506 ± 0.029
2.087TyrAsp: 2.087 ± 0.068
1.975TyrGlu: 1.975 ± 0.059
1.182TyrPhe: 1.182 ± 0.056
2.406TyrGly: 2.406 ± 0.071
0.43TyrHis: 0.43 ± 0.029
1.361TyrIle: 1.361 ± 0.045
0.984TyrLys: 0.984 ± 0.04
2.583TyrLeu: 2.583 ± 0.073
0.768TyrMet: 0.768 ± 0.037
0.828TyrAsn: 0.828 ± 0.042
1.256TyrPro: 1.256 ± 0.043
0.774TyrGln: 0.774 ± 0.038
1.815TyrArg: 1.815 ± 0.053
1.462TyrSer: 1.462 ± 0.052
1.492TyrThr: 1.492 ± 0.056
2.137TyrVal: 2.137 ± 0.052
0.268TyrTrp: 0.268 ± 0.024
0.888TyrTyr: 0.888 ± 0.05
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1794 proteins (600490 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski