Amino acid dipepetide frequency for Hubei mosquito virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.509AlaAla: 2.509 ± 1.327
2.509AlaCys: 2.509 ± 1.327
1.255AlaAsp: 1.255 ± 0.664
5.019AlaGlu: 5.019 ± 3.889
1.255AlaPhe: 1.255 ± 0.664
6.274AlaGly: 6.274 ± 1.137
5.019AlaHis: 5.019 ± 0.473
1.255AlaIle: 1.255 ± 0.664
7.528AlaLys: 7.528 ± 1.801
10.038AlaLeu: 10.038 ± 3.128
0.0AlaMet: 0.0 ± 0.0
0.0AlaAsn: 0.0 ± 0.0
1.255AlaPro: 1.255 ± 0.664
3.764AlaGln: 3.764 ± 2.371
5.019AlaArg: 5.019 ± 0.473
6.274AlaSer: 6.274 ± 1.044
3.764AlaThr: 3.764 ± 0.19
5.019AlaVal: 5.019 ± 0.473
2.509AlaTrp: 2.509 ± 1.327
2.509AlaTyr: 2.509 ± 1.327
0.0AlaXaa: 0.0 ± 0.0
Cys
3.764CysAla: 3.764 ± 0.19
0.0CysCys: 0.0 ± 0.0
1.255CysAsp: 1.255 ± 0.664
2.509CysGlu: 2.509 ± 3.035
3.764CysPhe: 3.764 ± 0.19
3.764CysGly: 3.764 ± 2.371
0.0CysHis: 0.0 ± 0.0
1.255CysIle: 1.255 ± 0.664
0.0CysLys: 0.0 ± 0.0
3.764CysLeu: 3.764 ± 0.19
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.255CysPro: 1.255 ± 1.517
1.255CysGln: 1.255 ± 1.517
2.509CysArg: 2.509 ± 0.854
5.019CysSer: 5.019 ± 1.708
2.509CysThr: 2.509 ± 1.327
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.509AspAla: 2.509 ± 1.327
0.0AspCys: 0.0 ± 0.0
3.764AspAsp: 3.764 ± 0.19
2.509AspGlu: 2.509 ± 1.327
1.255AspPhe: 1.255 ± 1.517
3.764AspGly: 3.764 ± 0.19
0.0AspHis: 0.0 ± 0.0
1.255AspIle: 1.255 ± 0.664
2.509AspLys: 2.509 ± 1.327
3.764AspLeu: 3.764 ± 1.991
2.509AspMet: 2.509 ± 0.854
0.0AspAsn: 0.0 ± 0.0
1.255AspPro: 1.255 ± 0.664
1.255AspGln: 1.255 ± 1.517
6.274AspArg: 6.274 ± 1.137
2.509AspSer: 2.509 ± 0.854
1.255AspThr: 1.255 ± 1.517
2.509AspVal: 2.509 ± 0.854
0.0AspTrp: 0.0 ± 0.0
5.019AspTyr: 5.019 ± 2.654
0.0AspXaa: 0.0 ± 0.0
Glu
6.274GluAla: 6.274 ± 1.044
2.509GluCys: 2.509 ± 3.035
0.0GluAsp: 0.0 ± 0.0
0.0GluGlu: 0.0 ± 0.0
8.783GluPhe: 8.783 ± 0.283
2.509GluGly: 2.509 ± 0.854
1.255GluHis: 1.255 ± 0.664
1.255GluIle: 1.255 ± 0.664
1.255GluLys: 1.255 ± 0.664
7.528GluLeu: 7.528 ± 0.38
3.764GluMet: 3.764 ± 2.371
2.509GluAsn: 2.509 ± 1.327
3.764GluPro: 3.764 ± 2.371
1.255GluGln: 1.255 ± 0.664
0.0GluArg: 0.0 ± 0.0
1.255GluSer: 1.255 ± 0.664
1.255GluThr: 1.255 ± 0.664
1.255GluVal: 1.255 ± 0.664
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
6.274PheCys: 6.274 ± 3.225
1.255PheAsp: 1.255 ± 0.664
2.509PheGlu: 2.509 ± 1.327
0.0PhePhe: 0.0 ± 0.0
1.255PheGly: 1.255 ± 0.664
1.255PheHis: 1.255 ± 0.664
3.764PheIle: 3.764 ± 0.19
0.0PheLys: 0.0 ± 0.0
2.509PheLeu: 2.509 ± 0.854
2.509PheMet: 2.509 ± 1.071
0.0PheAsn: 0.0 ± 0.0
8.783PhePro: 8.783 ± 0.283
1.255PheGln: 1.255 ± 0.664
3.764PheArg: 3.764 ± 1.991
5.019PheSer: 5.019 ± 3.889
5.019PheThr: 5.019 ± 2.654
1.255PheVal: 1.255 ± 0.664
1.255PheTrp: 1.255 ± 0.664
1.255PheTyr: 1.255 ± 0.664
0.0PheXaa: 0.0 ± 0.0
Gly
2.509GlyAla: 2.509 ± 3.035
1.255GlyCys: 1.255 ± 0.664
1.255GlyAsp: 1.255 ± 0.664
6.274GlyGlu: 6.274 ± 3.318
1.255GlyPhe: 1.255 ± 1.517
8.783GlyGly: 8.783 ± 1.898
0.0GlyHis: 0.0 ± 0.0
5.019GlyIle: 5.019 ± 3.889
6.274GlyLys: 6.274 ± 3.318
5.019GlyLeu: 5.019 ± 1.708
2.509GlyMet: 2.509 ± 1.327
0.0GlyAsn: 0.0 ± 0.0
5.019GlyPro: 5.019 ± 1.708
3.764GlyGln: 3.764 ± 0.19
5.019GlyArg: 5.019 ± 0.473
12.547GlySer: 12.547 ± 0.093
6.274GlyThr: 6.274 ± 1.137
3.764GlyVal: 3.764 ± 2.371
1.255GlyTrp: 1.255 ± 1.517
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.509HisAla: 2.509 ± 0.854
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.255HisGlu: 1.255 ± 1.517
0.0HisPhe: 0.0 ± 0.0
2.509HisGly: 2.509 ± 1.327
0.0HisHis: 0.0 ± 0.0
1.255HisIle: 1.255 ± 0.664
1.255HisLys: 1.255 ± 1.517
5.019HisLeu: 5.019 ± 0.473
0.0HisMet: 0.0 ± 0.0
1.255HisAsn: 1.255 ± 1.517
0.0HisPro: 0.0 ± 0.0
2.509HisGln: 2.509 ± 1.327
1.255HisArg: 1.255 ± 1.517
2.509HisSer: 2.509 ± 0.854
0.0HisThr: 0.0 ± 0.0
1.255HisVal: 1.255 ± 1.517
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.255IleAla: 1.255 ± 0.664
0.0IleCys: 0.0 ± 0.0
6.274IleAsp: 6.274 ± 1.044
2.509IleGlu: 2.509 ± 0.854
1.255IlePhe: 1.255 ± 0.664
1.255IleGly: 1.255 ± 0.664
0.0IleHis: 0.0 ± 0.0
6.274IleIle: 6.274 ± 1.137
0.0IleLys: 0.0 ± 0.0
3.764IleLeu: 3.764 ± 0.19
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
3.764IlePro: 3.764 ± 0.19
2.509IleGln: 2.509 ± 0.854
3.764IleArg: 3.764 ± 0.19
1.255IleSer: 1.255 ± 0.664
2.509IleThr: 2.509 ± 0.854
6.274IleVal: 6.274 ± 1.044
0.0IleTrp: 0.0 ± 0.0
2.509IleTyr: 2.509 ± 1.327
0.0IleXaa: 0.0 ± 0.0
Lys
2.509LysAla: 2.509 ± 1.327
1.255LysCys: 1.255 ± 0.664
0.0LysAsp: 0.0 ± 0.0
1.255LysGlu: 1.255 ± 0.664
3.764LysPhe: 3.764 ± 1.991
3.764LysGly: 3.764 ± 0.19
1.255LysHis: 1.255 ± 0.664
0.0LysIle: 0.0 ± 0.0
3.764LysLys: 3.764 ± 0.19
5.019LysLeu: 5.019 ± 0.473
1.255LysMet: 1.255 ± 0.437
0.0LysAsn: 0.0 ± 0.0
3.764LysPro: 3.764 ± 1.991
1.255LysGln: 1.255 ± 0.664
8.783LysArg: 8.783 ± 0.283
2.509LysSer: 2.509 ± 1.327
5.019LysThr: 5.019 ± 0.473
2.509LysVal: 2.509 ± 1.327
2.509LysTrp: 2.509 ± 1.327
1.255LysTyr: 1.255 ± 0.664
0.0LysXaa: 0.0 ± 0.0
Leu
7.528LeuAla: 7.528 ± 3.982
3.764LeuCys: 3.764 ± 0.19
5.019LeuAsp: 5.019 ± 2.654
0.0LeuGlu: 0.0 ± 0.0
0.0LeuPhe: 0.0 ± 0.0
10.038LeuGly: 10.038 ± 0.947
3.764LeuHis: 3.764 ± 4.552
0.0LeuIle: 0.0 ± 0.0
3.764LeuLys: 3.764 ± 1.991
11.292LeuLeu: 11.292 ± 0.571
2.509LeuMet: 2.509 ± 1.327
1.255LeuAsn: 1.255 ± 0.664
10.038LeuPro: 10.038 ± 3.415
2.509LeuGln: 2.509 ± 1.327
6.274LeuArg: 6.274 ± 1.044
8.783LeuSer: 8.783 ± 4.079
1.255LeuThr: 1.255 ± 0.664
7.528LeuVal: 7.528 ± 0.38
1.255LeuTrp: 1.255 ± 0.664
2.509LeuTyr: 2.509 ± 1.327
0.0LeuXaa: 0.0 ± 0.0
Met
1.255MetAla: 1.255 ± 0.664
0.0MetCys: 0.0 ± 0.0
1.255MetAsp: 1.255 ± 0.664
0.0MetGlu: 0.0 ± 0.0
1.255MetPhe: 1.255 ± 1.517
1.255MetGly: 1.255 ± 0.664
0.0MetHis: 0.0 ± 0.0
1.255MetIle: 1.255 ± 1.517
1.255MetLys: 1.255 ± 0.664
1.255MetLeu: 1.255 ± 0.664
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
3.764MetGln: 3.764 ± 0.19
3.764MetArg: 3.764 ± 2.371
3.764MetSer: 3.764 ± 0.19
0.0MetThr: 0.0 ± 0.0
1.255MetVal: 1.255 ± 0.664
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
5.019AsnAla: 5.019 ± 2.654
0.0AsnCys: 0.0 ± 0.0
1.255AsnAsp: 1.255 ± 0.664
1.255AsnGlu: 1.255 ± 1.517
1.255AsnPhe: 1.255 ± 0.664
0.0AsnGly: 0.0 ± 0.0
2.509AsnHis: 2.509 ± 0.854
0.0AsnIle: 0.0 ± 0.0
0.0AsnLys: 0.0 ± 0.0
0.0AsnLeu: 0.0 ± 0.0
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
0.0AsnPro: 0.0 ± 0.0
0.0AsnGln: 0.0 ± 0.0
1.255AsnArg: 1.255 ± 0.664
0.0AsnSer: 0.0 ± 0.0
2.509AsnThr: 2.509 ± 1.327
1.255AsnVal: 1.255 ± 1.517
1.255AsnTrp: 1.255 ± 0.664
1.255AsnTyr: 1.255 ± 0.664
0.0AsnXaa: 0.0 ± 0.0
Pro
5.019ProAla: 5.019 ± 1.708
3.764ProCys: 3.764 ± 2.371
3.764ProAsp: 3.764 ± 0.19
2.509ProGlu: 2.509 ± 0.854
3.764ProPhe: 3.764 ± 0.19
5.019ProGly: 5.019 ± 1.708
2.509ProHis: 2.509 ± 0.854
5.019ProIle: 5.019 ± 0.473
5.019ProLys: 5.019 ± 0.473
5.019ProLeu: 5.019 ± 0.473
2.509ProMet: 2.509 ± 0.854
2.509ProAsn: 2.509 ± 0.854
6.274ProPro: 6.274 ± 5.406
2.509ProGln: 2.509 ± 0.854
3.764ProArg: 3.764 ± 0.19
3.764ProSer: 3.764 ± 0.19
2.509ProThr: 2.509 ± 1.327
3.764ProVal: 3.764 ± 0.19
0.0ProTrp: 0.0 ± 0.0
1.255ProTyr: 1.255 ± 0.664
0.0ProXaa: 0.0 ± 0.0
Gln
5.019GlnAla: 5.019 ± 1.708
0.0GlnCys: 0.0 ± 0.0
2.509GlnAsp: 2.509 ± 0.854
2.509GlnGlu: 2.509 ± 1.327
2.509GlnPhe: 2.509 ± 0.854
7.528GlnGly: 7.528 ± 4.742
1.255GlnHis: 1.255 ± 1.517
1.255GlnIle: 1.255 ± 0.664
1.255GlnLys: 1.255 ± 0.664
2.509GlnLeu: 2.509 ± 1.327
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
2.509GlnPro: 2.509 ± 1.327
1.255GlnGln: 1.255 ± 0.664
6.274GlnArg: 6.274 ± 1.137
2.509GlnSer: 2.509 ± 0.854
1.255GlnThr: 1.255 ± 1.517
2.509GlnVal: 2.509 ± 1.327
0.0GlnTrp: 0.0 ± 0.0
1.255GlnTyr: 1.255 ± 0.664
0.0GlnXaa: 0.0 ± 0.0
Arg
5.019ArgAla: 5.019 ± 0.473
2.509ArgCys: 2.509 ± 1.327
3.764ArgAsp: 3.764 ± 2.371
5.019ArgGlu: 5.019 ± 2.654
3.764ArgPhe: 3.764 ± 0.19
8.783ArgGly: 8.783 ± 1.898
2.509ArgHis: 2.509 ± 0.854
7.528ArgIle: 7.528 ± 1.801
7.528ArgLys: 7.528 ± 1.801
5.019ArgLeu: 5.019 ± 0.473
0.0ArgMet: 0.0 ± 0.0
0.0ArgAsn: 0.0 ± 0.0
5.019ArgPro: 5.019 ± 1.708
2.509ArgGln: 2.509 ± 0.854
12.547ArgArg: 12.547 ± 2.274
5.019ArgSer: 5.019 ± 2.654
5.019ArgThr: 5.019 ± 1.708
1.255ArgVal: 1.255 ± 1.517
3.764ArgTrp: 3.764 ± 1.991
2.509ArgTyr: 2.509 ± 1.327
0.0ArgXaa: 0.0 ± 0.0
Ser
7.528SerAla: 7.528 ± 1.801
3.764SerCys: 3.764 ± 2.371
2.509SerAsp: 2.509 ± 3.035
2.509SerGlu: 2.509 ± 0.854
7.528SerPhe: 7.528 ± 3.982
5.019SerGly: 5.019 ± 0.473
1.255SerHis: 1.255 ± 0.664
5.019SerIle: 5.019 ± 0.473
3.764SerLys: 3.764 ± 2.371
6.274SerLeu: 6.274 ± 1.137
1.255SerMet: 1.255 ± 1.517
2.509SerAsn: 2.509 ± 1.327
3.764SerPro: 3.764 ± 2.371
2.509SerGln: 2.509 ± 0.854
11.292SerArg: 11.292 ± 1.61
1.255SerSer: 1.255 ± 0.664
5.019SerThr: 5.019 ± 0.473
6.274SerVal: 6.274 ± 1.044
0.0SerTrp: 0.0 ± 0.0
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
5.019ThrAla: 5.019 ± 1.708
1.255ThrCys: 1.255 ± 1.517
1.255ThrAsp: 1.255 ± 0.664
2.509ThrGlu: 2.509 ± 0.854
3.764ThrPhe: 3.764 ± 1.991
1.255ThrGly: 1.255 ± 0.664
0.0ThrHis: 0.0 ± 0.0
2.509ThrIle: 2.509 ± 0.854
2.509ThrLys: 2.509 ± 1.327
6.274ThrLeu: 6.274 ± 1.044
0.0ThrMet: 0.0 ± 0.0
2.509ThrAsn: 2.509 ± 1.327
7.528ThrPro: 7.528 ± 1.801
1.255ThrGln: 1.255 ± 0.664
3.764ThrArg: 3.764 ± 0.19
5.019ThrSer: 5.019 ± 0.473
2.509ThrThr: 2.509 ± 1.327
0.0ThrVal: 0.0 ± 0.0
2.509ThrTrp: 2.509 ± 0.854
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
2.509ValAla: 2.509 ± 1.327
2.509ValCys: 2.509 ± 0.854
5.019ValAsp: 5.019 ± 2.654
5.019ValGlu: 5.019 ± 1.708
1.255ValPhe: 1.255 ± 1.517
2.509ValGly: 2.509 ± 0.854
0.0ValHis: 0.0 ± 0.0
0.0ValIle: 0.0 ± 0.0
2.509ValLys: 2.509 ± 1.327
2.509ValLeu: 2.509 ± 3.035
0.0ValMet: 0.0 ± 0.0
1.255ValAsn: 1.255 ± 0.664
5.019ValPro: 5.019 ± 1.708
6.274ValGln: 6.274 ± 1.044
2.509ValArg: 2.509 ± 1.327
3.764ValSer: 3.764 ± 1.991
2.509ValThr: 2.509 ± 3.035
5.019ValVal: 5.019 ± 3.889
0.0ValTrp: 0.0 ± 0.0
3.764ValTyr: 3.764 ± 2.371
0.0ValXaa: 0.0 ± 0.0
Trp
3.764TrpAla: 3.764 ± 1.991
0.0TrpCys: 0.0 ± 0.0
1.255TrpAsp: 1.255 ± 0.664
0.0TrpGlu: 0.0 ± 0.0
1.255TrpPhe: 1.255 ± 0.664
1.255TrpGly: 1.255 ± 0.664
0.0TrpHis: 0.0 ± 0.0
1.255TrpIle: 1.255 ± 1.517
1.255TrpLys: 1.255 ± 0.664
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
2.509TrpAsn: 2.509 ± 0.854
0.0TrpPro: 0.0 ± 0.0
1.255TrpGln: 1.255 ± 0.664
0.0TrpArg: 0.0 ± 0.0
2.509TrpSer: 2.509 ± 1.327
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.255TyrAla: 1.255 ± 0.664
1.255TyrCys: 1.255 ± 0.664
1.255TyrAsp: 1.255 ± 0.664
1.255TyrGlu: 1.255 ± 0.664
1.255TyrPhe: 1.255 ± 0.664
1.255TyrGly: 1.255 ± 0.664
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
1.255TyrLys: 1.255 ± 0.664
2.509TyrLeu: 2.509 ± 0.854
1.255TyrMet: 1.255 ± 0.664
2.509TyrAsn: 2.509 ± 1.327
1.255TyrPro: 1.255 ± 0.664
1.255TyrGln: 1.255 ± 0.664
1.255TyrArg: 1.255 ± 0.664
3.764TyrSer: 3.764 ± 1.991
1.255TyrThr: 1.255 ± 0.664
1.255TyrVal: 1.255 ± 1.517
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (798 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski