Amino acid dipepetide frequency for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.897AlaAla: 5.897 ± 0.043	1.463AlaCys: 1.463 ± 0.016	2.816AlaAsp: 2.816 ± 0.019	4.418AlaGlu: 4.418 ± 0.033	2.763AlaPhe: 2.763 ± 0.023	4.29AlaGly: 4.29 ± 0.03	1.642AlaHis: 1.642 ± 0.018	2.943AlaIle: 2.943 ± 0.025	3.378AlaLys: 3.378 ± 0.029	7.158AlaLeu: 7.158 ± 0.038	1.616AlaMet: 1.616 ± 0.015	2.022AlaAsn: 2.022 ± 0.017	3.713AlaPro: 3.713 ± 0.03	3.128AlaGln: 3.128 ± 0.026	3.387AlaArg: 3.387 ± 0.023	5.743AlaSer: 5.743 ± 0.033	3.61AlaThr: 3.61 ± 0.023	4.725AlaVal: 4.725 ± 0.028	0.789AlaTrp: 0.789 ± 0.011	1.596AlaTyr: 1.596 ± 0.016	0.003AlaXaa: 0.003 ± 0.001
Cys	1.327CysAla: 1.327 ± 0.019	0.675CysCys: 0.675 ± 0.015	1.093CysAsp: 1.093 ± 0.022	1.245CysGlu: 1.245 ± 0.019	0.937CysPhe: 0.937 ± 0.012	1.772CysGly: 1.772 ± 0.028	0.726CysHis: 0.726 ± 0.013	0.986CysIle: 0.986 ± 0.012	1.175CysLys: 1.175 ± 0.016	2.287CysLeu: 2.287 ± 0.021	0.508CysMet: 0.508 ± 0.009	0.815CysAsn: 0.815 ± 0.015	1.442CysPro: 1.442 ± 0.023	1.095CysGln: 1.095 ± 0.018	1.278CysArg: 1.278 ± 0.015	2.162CysSer: 2.162 ± 0.022	1.188CysThr: 1.188 ± 0.013	1.404CysVal: 1.404 ± 0.02	0.317CysTrp: 0.317 ± 0.006	0.639CysTyr: 0.639 ± 0.011	0.001CysXaa: 0.001 ± 0.0
Asp	2.789AspAla: 2.789 ± 0.02	1.055AspCys: 1.055 ± 0.015	2.59AspAsp: 2.59 ± 0.026	3.286AspGlu: 3.286 ± 0.028	2.126AspPhe: 2.126 ± 0.019	3.13AspGly: 3.13 ± 0.027	1.163AspHis: 1.163 ± 0.014	2.668AspIle: 2.668 ± 0.024	2.466AspLys: 2.466 ± 0.02	4.933AspLeu: 4.933 ± 0.031	1.195AspMet: 1.195 ± 0.012	1.705AspAsn: 1.705 ± 0.018	2.957AspPro: 2.957 ± 0.069	1.821AspGln: 1.821 ± 0.016	2.449AspArg: 2.449 ± 0.02	4.206AspSer: 4.206 ± 0.031	2.643AspThr: 2.643 ± 0.03	3.037AspVal: 3.037 ± 0.028	0.622AspTrp: 0.622 ± 0.009	1.407AspTyr: 1.407 ± 0.014	0.001AspXaa: 0.001 ± 0.0
Glu	5.061GluAla: 5.061 ± 0.036	1.36GluCys: 1.36 ± 0.024	4.357GluAsp: 4.357 ± 0.035	8.128GluGlu: 8.128 ± 0.086	2.028GluPhe: 2.028 ± 0.018	4.059GluGly: 4.059 ± 0.032	1.535GluHis: 1.535 ± 0.013	2.926GluIle: 2.926 ± 0.024	5.189GluLys: 5.189 ± 0.041	6.249GluLeu: 6.249 ± 0.037	1.684GluMet: 1.684 ± 0.015	2.955GluAsn: 2.955 ± 0.024	3.121GluPro: 3.121 ± 0.033	3.081GluGln: 3.081 ± 0.03	3.666GluArg: 3.666 ± 0.03	4.224GluSer: 4.224 ± 0.028	3.32GluThr: 3.32 ± 0.033	4.129GluVal: 4.129 ± 0.032	0.67GluTrp: 0.67 ± 0.01	1.51GluTyr: 1.51 ± 0.019	0.002GluXaa: 0.002 ± 0.001
Phe	1.991PheAla: 1.991 ± 0.018	1.076PheCys: 1.076 ± 0.015	1.668PheAsp: 1.668 ± 0.016	1.923PheGlu: 1.923 ± 0.015	1.784PhePhe: 1.784 ± 0.023	2.258PheGly: 2.258 ± 0.022	1.074PheHis: 1.074 ± 0.015	1.973PheIle: 1.973 ± 0.017	1.774PheLys: 1.774 ± 0.017	4.449PheLeu: 4.449 ± 0.034	0.858PheMet: 0.858 ± 0.011	1.334PheAsn: 1.334 ± 0.014	2.047PhePro: 2.047 ± 0.017	1.815PheGln: 1.815 ± 0.015	1.985PheArg: 1.985 ± 0.017	3.544PheSer: 3.544 ± 0.029	2.134PheThr: 2.134 ± 0.017	2.259PheVal: 2.259 ± 0.019	0.52PheTrp: 0.52 ± 0.009	1.289PheTyr: 1.289 ± 0.015	0.001PheXaa: 0.001 ± 0.0
Gly	4.064GlyAla: 4.064 ± 0.032	1.339GlyCys: 1.339 ± 0.017	3.088GlyAsp: 3.088 ± 0.028	3.847GlyGlu: 3.847 ± 0.034	2.454GlyPhe: 2.454 ± 0.025	4.466GlyGly: 4.466 ± 0.041	1.723GlyHis: 1.723 ± 0.019	2.755GlyIle: 2.755 ± 0.022	3.78GlyLys: 3.78 ± 0.027	5.874GlyLeu: 5.874 ± 0.032	1.358GlyMet: 1.358 ± 0.014	2.348GlyAsn: 2.348 ± 0.019	3.76GlyPro: 3.76 ± 0.04	2.737GlyGln: 2.737 ± 0.022	3.53GlyArg: 3.53 ± 0.028	5.647GlySer: 5.647 ± 0.041	3.631GlyThr: 3.631 ± 0.026	3.54GlyVal: 3.54 ± 0.023	0.779GlyTrp: 0.779 ± 0.009	1.709GlyTyr: 1.709 ± 0.018	0.005GlyXaa: 0.005 ± 0.001
His	1.305HisAla: 1.305 ± 0.014	0.77HisCys: 0.77 ± 0.015	0.887HisAsp: 0.887 ± 0.01	1.285HisGlu: 1.285 ± 0.015	1.151HisPhe: 1.151 ± 0.011	1.536HisGly: 1.536 ± 0.016	0.901HisHis: 0.901 ± 0.014	1.311HisIle: 1.311 ± 0.014	1.308HisLys: 1.308 ± 0.015	3.075HisLeu: 3.075 ± 0.022	0.653HisMet: 0.653 ± 0.01	0.877HisAsn: 0.877 ± 0.01	1.671HisPro: 1.671 ± 0.021	1.349HisGln: 1.349 ± 0.018	1.645HisArg: 1.645 ± 0.018	2.42HisSer: 2.42 ± 0.021	1.691HisThr: 1.691 ± 0.026	1.525HisVal: 1.525 ± 0.015	0.374HisTrp: 0.374 ± 0.006	0.852HisTyr: 0.852 ± 0.011	0.001HisXaa: 0.001 ± 0.0
Ile	2.587IleAla: 2.587 ± 0.018	1.174IleCys: 1.174 ± 0.013	1.963IleAsp: 1.963 ± 0.017	2.407IleGlu: 2.407 ± 0.021	1.983IlePhe: 1.983 ± 0.021	2.198IleGly: 2.198 ± 0.018	1.432IleHis: 1.432 ± 0.019	2.451IleIle: 2.451 ± 0.023	2.493IleLys: 2.493 ± 0.025	4.83IleLeu: 4.83 ± 0.039	1.052IleMet: 1.052 ± 0.014	1.771IleAsn: 1.771 ± 0.016	2.65IlePro: 2.65 ± 0.021	2.252IleGln: 2.252 ± 0.018	2.378IleArg: 2.378 ± 0.022	3.732IleSer: 3.732 ± 0.026	2.623IleThr: 2.623 ± 0.03	2.619IleVal: 2.619 ± 0.023	0.533IleTrp: 0.533 ± 0.009	1.471IleTyr: 1.471 ± 0.015	0.001IleXaa: 0.001 ± 0.0
Lys	4.172LysAla: 4.172 ± 0.03	1.118LysCys: 1.118 ± 0.018	3.141LysAsp: 3.141 ± 0.027	4.981LysGlu: 4.981 ± 0.039	1.706LysPhe: 1.706 ± 0.015	3.228LysGly: 3.228 ± 0.025	1.432LysHis: 1.432 ± 0.014	2.606LysIle: 2.606 ± 0.022	4.906LysLys: 4.906 ± 0.057	5.083LysLeu: 5.083 ± 0.03	1.491LysMet: 1.491 ± 0.016	2.285LysAsn: 2.285 ± 0.021	3.047LysPro: 3.047 ± 0.03	2.581LysGln: 2.581 ± 0.022	3.273LysArg: 3.273 ± 0.026	3.842LysSer: 3.842 ± 0.027	3.106LysThr: 3.106 ± 0.022	3.559LysVal: 3.559 ± 0.031	0.587LysTrp: 0.587 ± 0.01	1.554LysTyr: 1.554 ± 0.016	0.001LysXaa: 0.001 ± 0.0
Leu	6.898LeuAla: 6.898 ± 0.04	2.386LeuCys: 2.386 ± 0.027	4.786LeuAsp: 4.786 ± 0.035	6.959LeuGlu: 6.959 ± 0.048	3.603LeuPhe: 3.603 ± 0.03	5.996LeuGly: 5.996 ± 0.032	2.816LeuHis: 2.816 ± 0.019	4.015LeuIle: 4.015 ± 0.028	5.758LeuLys: 5.758 ± 0.034	11.086LeuLeu: 11.086 ± 0.069	2.213LeuMet: 2.213 ± 0.022	3.476LeuAsn: 3.476 ± 0.022	5.901LeuPro: 5.901 ± 0.035	5.775LeuGln: 5.775 ± 0.036	5.906LeuArg: 5.906 ± 0.033	8.308LeuSer: 8.308 ± 0.043	5.238LeuThr: 5.238 ± 0.029	5.838LeuVal: 5.838 ± 0.034	1.205LeuTrp: 1.205 ± 0.015	2.608LeuTyr: 2.608 ± 0.022	0.003LeuXaa: 0.003 ± 0.001
Met	2.078MetAla: 2.078 ± 0.017	0.446MetCys: 0.446 ± 0.007	1.317MetAsp: 1.317 ± 0.015	1.918MetGlu: 1.918 ± 0.014	0.779MetPhe: 0.779 ± 0.011	1.398MetGly: 1.398 ± 0.015	0.485MetHis: 0.485 ± 0.009	0.889MetIle: 0.889 ± 0.013	1.494MetLys: 1.494 ± 0.014	2.198MetLeu: 2.198 ± 0.018	0.587MetMet: 0.587 ± 0.011	0.936MetAsn: 0.936 ± 0.011	1.166MetPro: 1.166 ± 0.015	0.959MetGln: 0.959 ± 0.011	1.073MetArg: 1.073 ± 0.011	1.711MetSer: 1.711 ± 0.015	1.22MetThr: 1.22 ± 0.014	1.56MetVal: 1.56 ± 0.017	0.258MetTrp: 0.258 ± 0.006	0.709MetTyr: 0.709 ± 0.011	0.001MetXaa: 0.001 ± 0.0
Asn	2.001AsnAla: 2.001 ± 0.018	0.857AsnCys: 0.857 ± 0.012	1.45AsnAsp: 1.45 ± 0.015	2.078AsnGlu: 2.078 ± 0.017	1.484AsnPhe: 1.484 ± 0.014	2.349AsnGly: 2.349 ± 0.022	0.946AsnHis: 0.946 ± 0.012	2.037AsnIle: 2.037 ± 0.019	2.185AsnLys: 2.185 ± 0.021	3.669AsnLeu: 3.669 ± 0.026	0.935AsnMet: 0.935 ± 0.011	1.463AsnAsn: 1.463 ± 0.019	2.247AsnPro: 2.247 ± 0.019	1.625AsnGln: 1.625 ± 0.017	1.804AsnArg: 1.804 ± 0.015	3.108AsnSer: 3.108 ± 0.022	1.999AsnThr: 1.999 ± 0.016	2.153AsnVal: 2.153 ± 0.021	0.447AsnTrp: 0.447 ± 0.008	1.089AsnTyr: 1.089 ± 0.012	0.001AsnXaa: 0.001 ± 0.0
Pro	4.323ProAla: 4.323 ± 0.038	1.229ProCys: 1.229 ± 0.023	2.753ProAsp: 2.753 ± 0.04	4.364ProGlu: 4.364 ± 0.034	1.991ProPhe: 1.991 ± 0.015	4.605ProGly: 4.605 ± 0.053	1.429ProHis: 1.429 ± 0.017	1.926ProIle: 1.926 ± 0.029	2.813ProLys: 2.813 ± 0.025	5.285ProLeu: 5.285 ± 0.035	1.192ProMet: 1.192 ± 0.012	1.804ProAsn: 1.804 ± 0.017	5.193ProPro: 5.193 ± 0.063	2.815ProGln: 2.815 ± 0.028	3.093ProArg: 3.093 ± 0.024	5.608ProSer: 5.608 ± 0.038	3.056ProThr: 3.056 ± 0.026	3.854ProVal: 3.854 ± 0.025	0.696ProTrp: 0.696 ± 0.01	1.495ProTyr: 1.495 ± 0.018	0.004ProXaa: 0.004 ± 0.001
Gln	3.473GlnAla: 3.473 ± 0.029	1.005GlnCys: 1.005 ± 0.017	2.337GlnAsp: 2.337 ± 0.015	3.824GlnGlu: 3.824 ± 0.035	1.349GlnPhe: 1.349 ± 0.014	2.844GlnGly: 2.844 ± 0.022	1.289GlnHis: 1.289 ± 0.014	1.948GlnIle: 1.948 ± 0.018	2.908GlnLys: 2.908 ± 0.023	4.753GlnLeu: 4.753 ± 0.032	1.163GlnMet: 1.163 ± 0.014	1.79GlnAsn: 1.79 ± 0.018	2.678GlnPro: 2.678 ± 0.024	2.911GlnGln: 2.911 ± 0.037	2.924GlnArg: 2.924 ± 0.029	3.146GlnSer: 3.146 ± 0.028	2.321GlnThr: 2.321 ± 0.019	2.938GlnVal: 2.938 ± 0.021	0.538GlnTrp: 0.538 ± 0.009	1.15GlnTyr: 1.15 ± 0.012	0.001GlnXaa: 0.001 ± 0.0
Arg	3.696ArgAla: 3.696 ± 0.027	1.178ArgCys: 1.178 ± 0.016	2.711ArgAsp: 2.711 ± 0.031	3.789ArgGlu: 3.789 ± 0.034	1.858ArgPhe: 1.858 ± 0.018	3.343ArgGly: 3.343 ± 0.025	1.529ArgHis: 1.529 ± 0.016	2.348ArgIle: 2.348 ± 0.018	3.654ArgLys: 3.654 ± 0.028	5.244ArgLeu: 5.244 ± 0.034	1.221ArgMet: 1.221 ± 0.014	2.111ArgAsn: 2.111 ± 0.016	2.987ArgPro: 2.987 ± 0.026	2.548ArgGln: 2.548 ± 0.021	4.02ArgArg: 4.02 ± 0.038	4.094ArgSer: 4.094 ± 0.034	2.789ArgThr: 2.789 ± 0.022	3.243ArgVal: 3.243 ± 0.025	0.677ArgTrp: 0.677 ± 0.009	1.52ArgTyr: 1.52 ± 0.014	0.003ArgXaa: 0.003 ± 0.001
Ser	5.134SerAla: 5.134 ± 0.03	1.981SerCys: 1.981 ± 0.024	3.86SerAsp: 3.86 ± 0.03	5.022SerGlu: 5.022 ± 0.031	3.171SerPhe: 3.171 ± 0.023	5.513SerGly: 5.513 ± 0.035	2.311SerHis: 2.311 ± 0.021	3.379SerIle: 3.379 ± 0.024	4.062SerLys: 4.062 ± 0.026	8.465SerLeu: 8.465 ± 0.042	1.771SerMet: 1.771 ± 0.016	2.653SerAsn: 2.653 ± 0.025	5.769SerPro: 5.769 ± 0.037	3.9SerGln: 3.9 ± 0.029	4.421SerArg: 4.421 ± 0.034	9.29SerSer: 9.29 ± 0.059	4.568SerThr: 4.568 ± 0.034	5.091SerVal: 5.091 ± 0.038	1.104SerTrp: 1.104 ± 0.013	2.187SerTyr: 2.187 ± 0.021	0.003SerXaa: 0.003 ± 0.001
Thr	3.746ThrAla: 3.746 ± 0.025	1.399ThrCys: 1.399 ± 0.02	2.499ThrAsp: 2.499 ± 0.027	3.579ThrGlu: 3.579 ± 0.036	2.22ThrPhe: 2.22 ± 0.017	3.595ThrGly: 3.595 ± 0.03	1.428ThrHis: 1.428 ± 0.018	2.47ThrIle: 2.47 ± 0.026	2.717ThrLys: 2.717 ± 0.026	5.539ThrLeu: 5.539 ± 0.029	1.205ThrMet: 1.205 ± 0.013	1.739ThrAsn: 1.739 ± 0.016	3.54ThrPro: 3.54 ± 0.031	2.398ThrGln: 2.398 ± 0.022	2.5ThrArg: 2.5 ± 0.024	4.663ThrSer: 4.663 ± 0.033	3.052ThrThr: 3.052 ± 0.033	4.068ThrVal: 4.068 ± 0.032	0.703ThrTrp: 0.703 ± 0.013	1.449ThrTyr: 1.449 ± 0.014	0.003ThrXaa: 0.003 ± 0.001
Val	4.329ValAla: 4.329 ± 0.023	1.575ValCys: 1.575 ± 0.017	2.94ValAsp: 2.94 ± 0.021	3.77ValGlu: 3.77 ± 0.03	2.602ValPhe: 2.602 ± 0.022	3.44ValGly: 3.44 ± 0.024	1.632ValHis: 1.632 ± 0.015	3.014ValIle: 3.014 ± 0.024	3.372ValLys: 3.372 ± 0.03	6.576ValLeu: 6.576 ± 0.037	1.487ValMet: 1.487 ± 0.017	2.234ValAsn: 2.234 ± 0.02	3.767ValPro: 3.767 ± 0.032	2.74ValGln: 2.74 ± 0.02	2.98ValArg: 2.98 ± 0.022	5.058ValSer: 5.058 ± 0.027	4.007ValThr: 4.007 ± 0.039	4.234ValVal: 4.234 ± 0.033	0.76ValTrp: 0.76 ± 0.013	1.694ValTyr: 1.694 ± 0.017	0.003ValXaa: 0.003 ± 0.001
Trp	0.802TrpAla: 0.802 ± 0.011	0.252TrpCys: 0.252 ± 0.006	0.657TrpAsp: 0.657 ± 0.011	0.805TrpGlu: 0.805 ± 0.011	0.462TrpPhe: 0.462 ± 0.009	0.744TrpGly: 0.744 ± 0.011	0.312TrpHis: 0.312 ± 0.006	0.547TrpIle: 0.547 ± 0.009	0.826TrpLys: 0.826 ± 0.011	1.246TrpLeu: 1.246 ± 0.015	0.319TrpMet: 0.319 ± 0.007	0.523TrpAsn: 0.523 ± 0.008	0.528TrpPro: 0.528 ± 0.009	0.528TrpGln: 0.528 ± 0.008	0.707TrpArg: 0.707 ± 0.012	0.877TrpSer: 0.877 ± 0.011	0.698TrpThr: 0.698 ± 0.011	0.76TrpVal: 0.76 ± 0.011	0.196TrpTrp: 0.196 ± 0.006	0.355TrpTyr: 0.355 ± 0.008	0.001TrpXaa: 0.001 ± 0.0
Tyr	1.422TyrAla: 1.422 ± 0.015	0.73TyrCys: 0.73 ± 0.011	1.334TyrAsp: 1.334 ± 0.017	1.623TyrGlu: 1.623 ± 0.017	1.306TyrPhe: 1.306 ± 0.014	1.664TyrGly: 1.664 ± 0.021	0.783TyrHis: 0.783 ± 0.01	1.407TyrIle: 1.407 ± 0.015	1.441TyrLys: 1.441 ± 0.018	2.774TyrLeu: 2.774 ± 0.02	0.673TyrMet: 0.673 ± 0.008	1.087TyrAsn: 1.087 ± 0.012	1.337TyrPro: 1.337 ± 0.016	1.23TyrGln: 1.23 ± 0.014	1.541TyrArg: 1.541 ± 0.016	2.267TyrSer: 2.267 ± 0.018	1.619TyrThr: 1.619 ± 0.014	1.677TyrVal: 1.677 ± 0.016	0.37TyrTrp: 0.37 ± 0.008	0.942TyrTyr: 0.942 ± 0.012	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.003XaaAla: 0.003 ± 0.001	0.001XaaCys: 0.001 ± 0.0	0.002XaaAsp: 0.002 ± 0.0	0.002XaaGlu: 0.002 ± 0.001	0.001XaaPhe: 0.001 ± 0.0	0.004XaaGly: 0.004 ± 0.001	0.001XaaHis: 0.001 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.003XaaLeu: 0.003 ± 0.001	0.001XaaMet: 0.001 ± 0.0	0.001XaaAsn: 0.001 ± 0.0	0.005XaaPro: 0.005 ± 0.001	0.001XaaGln: 0.001 ± 0.0	0.004XaaArg: 0.004 ± 0.001	0.005XaaSer: 0.005 ± 0.001	0.001XaaThr: 0.001 ± 0.0	0.002XaaVal: 0.002 ± 0.0	0.001XaaTrp: 0.001 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	2.184XaaXaa: 2.184 ± 0.227

Statistics based on 23885 proteins (8795621 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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